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List of works by Lucas B Sullivan

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

scientific article

Altered metabolite levels in cancer: implications for tumour biology and cancer therapy.

scientific article published on 23 September 2016

Aspartate is an endogenous metabolic limitation for tumour growth

scientific article published on 25 June 2018

Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes.

scientific article published on February 2016

Biophysical changes reduce energetic demand in growth factor–deprived lymphocytes.

scientific article published in March 2016

Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited

scientific article published in 2022

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin

scientific article published on 12 October 2016

Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer

scientific article published on 3 February 2016

Extracellular vesicles: Taking metabolism on the road.

scientific article published in August 2017

Free Asparagine or Die: Cancer Cells Require Proteasomal Protein Breakdown to Survive Asparagine Depletion

scientific article published on 01 November 2020

Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy

scientific article published on 11 December 2017

MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme

scientific article published on 24 September 2020

Metabolic Frugality Marks Cancer Cells for Immune Targeting

scientific article published on 01 September 2018

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

scientific article

Mitochondria and telomeres: the promiscuous roles of TIN2.

scientific article published in September 2012

Mitochondrial metabolism in TCA cycle mutant cancer cells.

scientific article published on 13 December 2013

Mitochondrial reactive oxygen species and cancer.

scientific article

Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.

scientific article

Reductive carboxylation supports growth in tumour cells with defective mitochondria.

scientific article published on 20 November 2011

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.

scientific article published on July 2015

The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling.

scientific article

Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy

scientific article

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