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List of works by John M Asara

A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain

scientific article

A secreted tyrosine kinase acts in the extracellular environment

scientific article

AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions

scientific article published on 28 January 2019

An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.

scientific article published on 15 January 2018

An automated method for the analysis of stable isotope labeling data in proteomics

scientific article

An enolase inhibitor for the targeted treatment of ENO1-deleted cancers

scientific article published on 23 November 2020

Analyses of soft tissue from Tyrannosaurus rex suggest the presence of protein

scientific article published in April 2007

Author Correction: An enolase inhibitor for the targeted treatment of ENO1-deleted cancers

scientific article published on 18 December 2020

Author Correction: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

scientific article published on 01 May 2019

Author Correction: Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle

scientific article published on 28 August 2020

Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide

scientific article

Behavioral extremes of trait anxiety in mice are characterized by distinct metabolic profiles.

scientific article published on 30 July 2014

Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis

scientific article (publication date: May 2009)

C3b deposition on human erythrocytes induces the formation of a membrane skeleton-linked protein complex

scientific article

CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base

scientific article

Casein Kinase 1 Proteomics Reveal Prohibitin 2 Function in Molecular Clock ⬇️

scientific article published on February 27, 2012

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

scientific article

Centriole distal appendages promote membrane docking, leading to cilia initiation

scientific article

Characterization and analysis of the composition and dynamics of the mammalian riboproteome.

scientific article published on 19 September 2013

Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1

scientific article

Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer

scientific article published on 22 August 2012

Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling

scientific article published in December 2017

Data pre-processing in liquid chromatography-mass spectrometry-based proteomics

scientific article

Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors

scientific article

Direct stimulation of NADP+ synthesis through Akt-mediated phosphorylation of NAD kinase

scientific article published on 01 March 2019

Erratum: Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

article

Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon–mediated immunity ⬇️

scientific article published on July 10, 2011

Fetal deficiency of lin28 programs life-long aberrations in growth and glucose metabolism

scientific article published on August 2013

Fluoxetine Treatment Rescues Energy Metabolism Pathway Alterations in a Posttraumatic Stress Disorder Mouse Model

scientific article published on 30 April 2016

Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation

scientific article published on 01 January 2019

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.

scientific article published on 27 March 2013

Identification of immunoreactive material in mammoth fossils

scientific article

IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway

scientific article

Influence of threonine metabolism on S-adenosylmethionine and histone methylation

scientific article published on November 2012

Intercellular transfer of proteins as identified by stable isotope labeling of amino acids in cell culture

scientific article

Interpreting sequences from mastodon and T. rex.

scientific article

IsoSearch: An Untargeted and Unbiased Metabolite and Lipid Isotopomer Tracing Strategy from HR-LC-MS/MS Datasets

scientific article published on 30 July 2020

Ketamine's Effects on the Glutamatergic and GABAergic Systems: A Proteomics and Metabolomics Study in Mice

scientific article published on 15 November 2018

Ketamine's antidepressant effect is mediated by energy metabolism and antioxidant defense system

scientific article

LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control

scientific article published on 03 February 2020

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency

scientific article

Lin28 enhances tissue repair by reprogramming cellular metabolism

scientific article

Loss of RBF1 changes glutamine catabolism

scientific article (publication date: 15 January 2013)

Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival

scientific article

Metabolomic Profiling from Formalin-Fixed, Paraffin-Embedded Tumor Tissue Using Targeted LC/MS/MS: Application in Sarcoma ⬇️

scientific article published on October 3, 2011

Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells

scientific article

Molecular phylogenetics of mastodon and Tyrannosaurus rex.

scientific article

NextGen Brain Microdialysis: Applying Modern Metabolomics Technology to the Analysis of Extracellular Fluid in the Central Nervous System

scientific article

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.

scientific article

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

scientific article

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

scientific article

PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage

scientific article published on 19 June 2019

Perfusion decellularization of human and porcine lungs: bringing the matrix to clinical scale.

scientific article

Phosphoinositide 3-kinase pathway activation in phosphate and tensin homolog (PTEN)-deficient prostate cancer cells is independent of receptor tyrosine kinases and mediated by the p110beta and p110delta catalytic subunits

scientific article

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase

scientific article

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

scientific article (publication date: 28 January 2011)

Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation

scientific article

Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry

scientific article

Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor

scientific journal article

Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate

scientific journal article

Proteomic screening method for phosphopeptide motif binding proteins using peptide libraries

scientific article published on 2 August 2011

Purine and pyrimidine metabolism: Convergent evidence on chronic antidepressant treatment response in mice and humans

scientific article published on 12 October 2016

Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis

scientific article published on 28 March 2024

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

scientific article

Pyruvate kinase M2 is a phosphotyrosine-binding protein

scientific article

Raptor is phosphorylated by cdc2 during mitosis

scientific article

Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylation

scientific article

SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.

scientific article

SF2312 is a natural phosphonate inhibitor of enolase

scientific article

SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive

scientific article

SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression.

scientific article published on 2 September 2015

Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo

scientific article published on 16 November 2015

Serial-omics characterization of equine urine

scientific article

Serum proteomics and biomarkers in hepatocellular carcinoma and chronic liver disease

scientific article

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

scientific article published on 27 October 2013

Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle

scientific article published on 15 July 2020

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.

scientific article published on April 2016

Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells

scientific article published on 20 May 2022

TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1 ⬇️

scientific article published on July 12, 2012

Targeted deletion of PD-1 in myeloid cells induces antitumor immunity

scientific article published on 01 January 2020

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

scientific article

The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.

scientific article

The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3

scientific article

Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.

scientific article published on 8 March 2011

Vibrio cholerae ensures function of host proteins required for virulence through consumption of luminal methionine sulfoxide.

scientific article

Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition.

scientific article

mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR

scientific article

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