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List of works by Dylan W de Lange

A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention

scientific article published on 02 May 2019

A quarter of admitted poisoned patients have a mild poisoning and require no treatment: An observational study

scientific article published on 18 May 2019

Active von Willebrand factor predicts 28-day mortality in patients with systemic inflammatory response syndrome

scientific article published on 23 January 2014

Acute renal failure due to tobramycin intoxication during selective digestive tract decontamination

scientific article published on May 13, 2011

Adjusting for Disease Severity Across ICUs in Multicenter Studies

scientific article published on 01 August 2019

Alcohol and polyphenolic grape extract inhibit platelet adhesion in flowing blood.

scientific article published in December 2004

Association between administered oxygen, arterial partial oxygen pressure and mortality in mechanically ventilated intensive care unit patients.

scientific article published on 10 December 2008

Association of Whole Blood Tacrolimus Concentrations with Kidney Injury in Heart Transplantation Patients

scientific article published on 13 December 2017

Attitudes of physicians towards the care of critically ill elderly patients - a European survey

scientific article published on 26 October 2017

Baseline thrombospondin-1 concentrations are not associated with mortality in septic patients: a single-center cohort study on the intensive care unit.

scientific article published on 25 January 2017

Blood glucose amplitude variability as predictor for mortality in surgical and medical intensive care unit patients: a multicenter cohort study

scientific article published on 09 January 2012

Can we predict septic shock in patients with hospital-acquired pneumonia?

scientific article published on 11 November 2005

Candidemic complications in patients with intravascular catheters colonized with Candida species: an indication for preemptive antifungal therapy?

scientific article published on May 6, 2011

Cardiotoxicity screening of illicit drugs and new psychoactive substances (NPS) in human iPSC-derived cardiomyocytes using microelectrode array (MEA) recordings

scientific article published on 14 September 2019

Caring for the critically ill patients over 80: a narrative review

scientific article published on 26 November 2018

Comparing intensive care units by size or level

scientific article

Correction to: Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit

scientific article published on 01 September 2018

Cost-effectiveness of procalcitonin testing to guide antibiotic treatment duration in critically ill patients: results from a randomised controlled multicentre trial in the Netherlands

scientific article published on 13 November 2018

Cumulative Prognostic Score Predicting Mortality in Patients Older Than 80 Years Admitted to the ICU.

scientific article

Determinants of self-reported unacceptable outcome of intensive care treatment 1 year after discharge

scientific article published on 06 March 2019

Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUN gal infections Definitions in ICU patients ( FUNDICU ) project

scientific article published on 22 January 2019

Development and Validation of an Abbreviated Questionnaire to Easily Measure Cognitive Failure in ICU Survivors: A Multicenter Study.

scientific article published on 24 October 2017

Development of a Simple and Rapid Method to Measure the Free Fraction of Tacrolimus in Plasma Using Ultrafiltration and LC-MS/MS.

scientific article published on 31 October 2016

Differential effects of psychoactive substances on human wildtype and polymorphic T356M dopamine transporters (DAT)

scientific article published on 19 April 2019

Do corticosteroids have a role in preventing or reducing acute toxic lung injury caused by inhalation of chemical agents?

scientific article published on February 1, 2011

Do intensive care data on respiratory infections reflect influenza epidemics?

scientific article

Do we need new trials of procalcitonin-guided antibiotic therapy? A response

scientific article published on 23 March 2018

Does platelet hyperfunction explain grim survival rates after out-of-hospital cardiac arrest?

scientific article published in March 2009

Dose Reduction of Caspofungin in Intensive Care Unit Patients with Child Pugh B Will Result in Suboptimal Exposure.

scientific article published on 09 December 2015

Drink to prevent: review on the cardioprotective mechanisms of alcohol and red wine polyphenols.

scientific article

Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis.

scientific article published on 13 October 2017

Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial.

scientific article

Emergency Department to ICU Time Is Associated With Hospital Mortality: A Registry Analysis of 14,788 Patients From Six University Hospitals in The Netherlands

scientific article published on 01 November 2019

Estimating severity of influenza epidemics from severe acute respiratory infections (SARI) in intensive care units

article

Extracorporeal membrane oxygenation in the treatment of poisoned patients.

scientific article

From red wine to polyphenols and back: a journey through the history of the French Paradox.

scientific article published on 12 July 2006

Getting it right first time in a patient with Candida peritonitis

scientific article published on 01 December 2011

Healthcare-related costs in very elderly intensive care patients

scientific article published on 25 September 2018

High Variability of Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation

scientific article published on 01 February 2020

High tacrolimus blood concentrations early after lung transplantation and the risk of kidney injury

scientific article published on 28 January 2017

Hospital mortality is associated with ICU admission time.

scientific article

Huge variation in obtaining ethical permission for a non-interventional observational study in Europe

scientific article published on 03 June 2019

ICU beds: less is more? No

scientific article published on 26 May 2020

ICU respiratory admissions data for influenza severity surveillance?

In-hospital mortality and long-term survival of patients with acute intoxication admitted to the ICU

scientific article published on 01 June 2014

Increased mortality in systemic inflammatory response syndrome patients with high levels of coagulation factor VIIa

scientific article published on 01 December 2013

Influence of a strict glucose protocol on serum potassium and glucose concentrations and their association with mortality in intensive care patients

scientific article

Influence of mild therapeutic hypothermia after cardiac arrest on hospital mortality

scientific article published on 01 January 2011

Inhalational Methanol Intoxication: Emerging Issues in the Netherlands Resulting From Illegal Drug Production

scientific article published on 01 November 2019

Intoxication with Monkshood (Aconitum napellus)

scientific article

Is a Single Initial Procalcitonin Test Sufficient in Septic, Critically Ill Patients to Minimize Antibiotic Use?

scientific article published on 01 July 2017

Is it really safe to withhold folinic acid when less than 1000 mg/m2 methotrexate is ingested?

scientific article published on 26 April 2017

Long-Term Mental Health Problems After Delirium in the ICU.

scientific article

Long-Term Self-Reported Cognitive Problems After Delirium in the Intensive Care Unit and the Effect of Systemic Inflammation.

scientific article published on 24 March 2017

Long-term outcome of delirium during intensive care unit stay in survivors of critical illness: a prospective cohort study.

scientific article

Monocyte hyporesponsiveness and Toll-like receptor expression profiles in coronary artery bypass grafting and its clinical implications for postoperative inflammatory response and pneumonia: An observational cohort study

scientific article published on March 2015

Myeloperoxidase can differentiate between sepsis and non-infectious SIRS and predicts mortality in intensive care patients with SIRS

scientific article published on 15 September 2017

Neuropsychiatric outcome in subgroups of Intensive Care Unit survivors: Implications for after-care

scientific article published on 12 November 2019

Neutrophil CD64 expression as a longitudinal biomarker for severe disease and acute infection in critically ill patients.

scientific article

Outcome after hydrogen sulphide intoxication

scientific article published on 18 March 2016

Paroxysmal autonomic instability with dystonia in a patient with tuberculous meningitis: a case report

scientific article published on 10 September 2010

Perioperative glucocorticosteroid supplementation is not supported by evidence.

scientific article published on 04 February 2008

Pharmacokinetics of Anidulafungin in Critically Ill Intensive Care Unit Patients with Suspected or Proven Invasive Fungal Infections

scientific article

Pharmacokinetics of caspofungin in ICU patients

scientific article published on 19 August 2014

Pharmacokinetics of oseltamivir carboxylate in critically ill patients: each patient is unique

scientific article published on 27 February 2013

Population Pharmacokinetic Model and Pharmacokinetic Target Attainment of Micafungin in Intensive Care Unit Patients

scientific article published on 31 January 2017

Preventing persistent organ support in ICU patients

scientific article published in May 2017

Procalcitonin to guide antibiotic stewardship in intensive care - Authors'reply

scientific article published on 01 August 2016

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections.

scientific article published on 13 October 2017

Raising awareness for a low health-related quality of life in intoxicated ICU patients.

scientific article published on 15 May 2015

Rapid intake of alcohol (binge drinking) inhibits platelet adhesion to fibrinogen under flow.

scientific article published in October 2004

Red wine and red wine polyphenolic compounds but not alcohol inhibit ADP-induced platelet aggregation

scientific article published on 01 October 2003

Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study

scientific article published in July 2021

Sepsis at ICU admission does not decrease 30-day survival in very old patients: a post-hoc analysis of the VIP1 multinational cohort study

scientific article published on 13 May 2020

Short- and long-term outcome of HIV-infected patients admitted to the intensive care unit

scientific article published on 18 February 2011

Should this elderly patient be admitted to the ICU?

scientific article published on 22 January 2018

Should we deny ICU admission to the elderly? Ethical considerations in times of COVID-19

scientific article published on 09 June 2020

Single-center large-cohort study into quality of life in Dutch intensive care unit subgroups, 1 year after admission, using EuroQoL EQ-6D-3L.

scientific article published on 22 September 2014

Soluble P-selectin as a Biomarker for Infection and Survival in Patients With a Systemic Inflammatory Response Syndrome on the Intensive Care Unit

scientific article

Stop Antibiotics on guidance of Procalcitonin Study (SAPS): a randomised prospective multicenter investigator-initiated trial to analyse whether daily measurements of procalcitonin versus a standard-of-care approach can safely shorten antibiotic dur

scientific article

Survival and quality of life in patients acquiring acute kidney injury in the first 24 hours of ICU admission.

scientific article published on 17 March 2014

The ability of intensive care unit physicians to estimate long-term prognosis in survivors of critical illness.

scientific article published on 6 September 2017

The authors reply

scientific article published in January 2015

The effect of ICU-tailored drug-drug interaction alerts on medication prescribing and monitoring: protocol for a cluster randomized stepped-wedge trial

scientific article published on 13 August 2019

The etiology and outcome of non-traumatic coma in critical care: a systematic review.

scientific article published on 29 April 2015

The healthcare costs of intoxicated patients who survive ICU admission are higher than non-intoxicated ICU patients: a retrospective study combining healthcare insurance data and data from a Dutch national quality registry

article

The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years).

scientific article

The need for ICU admission in intoxicated patients: a prediction model

scientific article

The pitfalls of benchmarking ICUs*

scientific article published on 01 February 2015

The predictive value of early acute kidney injury for long-term survival and quality of life of critically ill patients

scientific article published on 03 August 2016

The status of intensive care medicine research and a future agenda for very old patients in the ICU.

scientific article published on 25 February 2017

The use of linked registries to assess long-term mortality of ICU patients.

scientific article published on January 2012

Treatment of Immunocompromised, Critically Ill Patients with Influenza A H1N1 Infection with a Combination of Oseltamivir, Amantadine, and Zanamivir.

scientific article published on 9 August 2015

Trends in short-term and 1-year mortality in very elderly intensive care patients in the Netherlands: a retrospective study from 2008 to 2014.

scientific article published on 13 July 2017

True changes in patient characteristics and outcomes or partially a reflection of different study populations?

article

Unbound Plasma, Total Plasma, and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation

scientific article published on 16 December 2019

Unusual cardiac tamponade

scientific article published on 22 February 2013

Validation of the clinical frailty score (CFS) in French language

scientific article published on 21 November 2019

Why would procalcitonin perform better in patients with a SOFA-score less than 8?

scientific article published on 01 October 2019

Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit.

scientific article

[Too old for the intensive care unit? Backgrounds and challenges]

scientific article published on 29 October 2019