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List of works by Zandrea Ambrose

A Novel Phenotype Links HIV-1 Capsid Stability to cGAS-Mediated DNA Sensing

scientific article published on 30 July 2019

A macaque model of HIV-1 infection

scholarly article

A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host.

scientific article

CA Mutation N57A Has Distinct Strain-Specific HIV-1 Capsid Uncoating and Infectivity Phenotypes

scientific article published on 17 April 2019

CG Dinucleotide Removal in Bioluminescent and Fluorescent Reporters Improves HIV-1 Replication and Reporter Gene Expression for Dual Imaging in Humanized Mice

scientific article published on 09 September 2021

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.

scientific article published on May 2007

Direct visualization of HIV-1 with correlative live-cell microscopy and cryo-electron tomography.

scientific article

Dysregulation of multiple inflammatory molecules in lymph node and ileum of macaques during RT-SHIV infection with or without antiretroviral therapy

scientific article

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.

scientific article published on 29 June 2016

Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay

scientific article published on 09 July 2013

Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV89.6 ⬇️

scientific article published on March 30, 2003

Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy

scientific article

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

scientific article published on 20 February 2014

HIV/AIDS: in search of an animal model.

scientific article published on 18 June 2007

Human Immunodeficiency Virus Type 1 Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection ⬇️

scientific article published on February 1, 2012

Immune Control of SHIV in Macaques Upon Mucosal Infection of Immunization ⬇️

doctoral thesis by Zandrea Ambrose, 2001

Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon.

scientific article published on 9 August 2017

Long-Acting Rilpivirine (RPV) Preexposure Prophylaxis Does Not Inhibit Vaginal Transmission of RPV-Resistant HIV-1 or Select for High-Frequency Drug Resistance in Humanized Mice

scientific article published on 31 March 2020

Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase

scientific article

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis

scientific article published on 17 December 2020

Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model

scientific article (publication date: 2013)

RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy

scientific article

Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants

scientific article published on 16 February 2016

Rilpivirine and Doravirine Have Complementary Efficacies Against NNRTI-Resistant HIV-1 Mutants.

scientific article

SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis

scientific article published on 30 July 2020

Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy

scientific article

The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs

scientific article published on 04 February 2009

Two Coselected Distal Mutations in HIV-1 Reverse Transcriptase (RT) Alter Susceptibility to Nonnucleoside RT Inhibitors and Nucleoside Analogs.

scientific article published on 15 May 2019

Ultrasensitive allele-specific PCR reveals rare preexisting drug-resistant variants and a large replicating virus population in macaques infected with a simian immunodeficiency virus containing human immunodeficiency virus reverse transcriptase

scientific article

Visualization and quantification of simian immunodeficiency virus-infected cells using non-invasive molecular imaging.

scientific article

Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy

scientific article

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