List of works - Michelle Monje

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG).

scientific article

A comparative study of brain tumor cells from different age and anatomical locations using 3D biomimetic hydrogels

scientific article published on 07 September 2020

ALK2 inhibitors display beneficial effects in preclinical models of mutant diffuse intrinsic pontine glioma

article

ANGIOGENESIS AND INVASION

Abstracts

article by L. Bie et al published 1 April 2013 in Neuro-Oncology

Activity Shapes Neural Circuit Form and Function: A Historical Perspective

scientific article published on 01 January 2020

An Active Role for Neurons in Glioma Progression: Making Sense of Scherer's Structures.

scientific article

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

scientific article published on 18 July 2019

Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication

scientific article published in 2022

BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

scientific article published in 2022

BSTM-04. NEURONAL-ACTIVITY SECRETED BDNF INCREASES DIPG PROLIFERATION

scientific article published on 23 April 2019

BT-02FUNCTIONALLY-DEFINED THERAPEUTIC TARGETS IN DIFFUSE INTRINSIC PONTINE GLIOMA.

scientific article published on 21 April 2015

BT-05FUNCTIONAL DIVERSITY AND CO-OPERATIVITY OF SUBCLONAL POPULATIONS OF PAEDIATRIC GLIOBLASTOMA AND DIFFUSE INTRINSIC PONTINE GLIOMA CELLS.

scientific article published on 21 April 2015

Bad wrap: Myelin and myelin plasticity in health and disease

scientific article published on 7 October 2017

Bespoke myelin tailored to neuron type

scientific article published on 01 December 2020

Brain Perfusion and Diffusion Abnormalities in Children Treated for Posterior Fossa Brain Tumors

scientific article

CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors

scientific article published on 17 January 2019

CBIO-48DECODING THE CELLULAR HETEROGENEITY OF MALIGNANT GLIOMA.

scientific article

CELL BIOLOGY AND SIGNALING

article

CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma

scientific article published on 31 March 2020

Calbindin overexpression buffers hippocampal cultures from the energetic impairments caused by glutamate

scientific article published in August 2001

Chemoradiation impairs normal developmental cortical thinning in medulloblastoma

scientific article published on 22 May 2017

Clinical patterns and biological correlates of cognitive dysfunction associated with cancer therapy

scientific article

Cognitive side effects of cancer therapy demonstrate a functional role for adult neurogenesis

scientific article published on 23 May 2011

Complete ocular paresis in a child with posterior fossa syndrome

scientific article published on 15 August 2012

Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study

scientific article published in September 2017

Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma

scientific article published on 01 January 2019

Cranial radiation therapy and damage to hippocampal neurogenesis

scientific article published on January 2008

DIPG-03. EXCITATORY SYNAPSES BETWEEN PRESYNAPTIC NEURONS AND POSTSYNAPTIC GLIOMA CELLS PROMOTE DIPG PROGRESSION

scientific article published on 22 June 2018

DIPG-03. TARGETING PI3K USING THE BLOOD BRAIN BARRIER PENETRABLE INHIBITOR, GDC-0084, FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

DIPG-09. HDAC INHIBITION IN THALAMIC AND SPINAL CORD H3K27M+ DIFFUSE MIDLINE GLIOMA

DIPG-11. NEURAL PRECURSOR CELL:GLIOMA INTERACTIONS MEDIATE TUMOR COLONIZATION OF THE SUBVENTRICULAR ZONE BY DIPG.

scientific article

DIPG-13. TRANSCRIPTIONAL DEPENDENCIES IN DIFFUSE INTRINSIC PONTINE GLIOMA.

scientific article

DIPG-21. ELECTRICAL INTEGRATION OF GLIOMA INTO NEURAL CIRCUITRY

scientific article published on 23 April 2019

DIPG-22. A PHASE 1 TRIAL OF THE HISTONE DEACETYLASE INHIBITOR PANOBINOSTAT IN PEDIATRIC PATIENTS WITH RECURRENT OR REFRACTORY DIFFUSE INTRINSIC PONTINE GLIOMA: A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY

DIPG-22. IDENTIFICATION OF THERAPEUTIC TARGETS IN DIPGS USING LARGE-SCALE RNAI SCREENING.

scientific article published on 31 May 2017

DIPG-26. NON-INFLAMMATORY EFFECT OF DIPG ON TUMOR-ASSOCIATED MICROGLIA.

scientific article published on 31 May 2017

DIPG-27. OPTIMIZING CLINICAL TRIAL DESIGN: PHARMACOKINETICS OF MARIZOMIB AND PANOBINOSTAT IN A NON-HUMAN PRIMATE MODEL

scientific article published on 23 April 2019

DIPG-29. GENOMIC LANDSCAPE OF DIFFUSE INTRINSIC PONTINE GLIOMA: AN ANALYSIS OF THE DIPG-BATS COHORT.

scientific article published on 31 May 2017

DIPG-36. ANTI-GD2 CHIMERIC ANTIGEN RECEPTOR T CELLS AS A POTENT IMMUNOTHERAPY REGIMEN IN XENOGRAFT MODELS OF HISTONE 3 K27M MUTANT DIFFUSE MIDLINE GLIOMA.

scientific article

DIPG-41. IDENTIFICATION OF BIRC5 AS A NOVEL THERAPEUTIC TARGET FOR DIFFUSE INTRINSIC PONTINE GLIOMA

scientific article published on 22 June 2018

DIPG-48. DIFFUSE INTRINSIC PONTINE GLIOMA CELLS ARE INTERCONNECTED BY ‘TUMOR MICROTUBES’

DIPG-52. ACTIVE CHROMATIN IN H3K27M DIPG REVEALS DISTINCT EPIGENETIC SUBTYPES AND SUBTYPE-SPECIFIC MECHANISMS OF PATHOGENESIS

DIPG-55. TARGETING SENESCENT CELLS WITH ABT-263 ENHANCES CELL DEATH INDUCED BY BMI1 INHIBITION AND IONIZING RADIATION IN DIPG

scientific article published on 22 June 2018

DIPG-69. CHARACTERISTICS OF PATIENTS ≥ 10 YEARS OF AGE WITH DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY

DIPG-70. CLINICAL, RADIOLOGICAL, PATHOLOGICAL AND MOLECULAR CHARACTERISTICS OF CHILDREN <3 YEARS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A REPORT FROM THE INTERNATIONAL DIPG REGISTRY

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.

scientific article published on March 2017

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

scientific article published in April 2018

Developmental origins and emerging therapeutic opportunities for childhood cancer

Diffuse Intrinsic Pontine Glioma: From Diagnosis to Next-Generation Clinical Trials

scientific article published on 10 July 2019

Diffuse Intrinsic Pontine Glioma: New Pathophysiological Insights and Emerging Therapeutic Targets

scientific article

Diffuse intrinsic pontine glioma: molecular landscape and emerging therapeutic targets

scientific article published on 01 November 2019

Diffusion-weighted MRI derived apparent diffusion coefficient identifies prognostically distinct subgroups of pediatric diffuse intrinsic pontine glioma

scientific article published on 13 February 2014

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors.

scientific article

Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice

scientific article published on 18 November 2019

Durable response of a radiation-induced, high-grade cerebellar glioma to temozolomide.

scientific article published in March 2007

EPID-12PSYCHIATRIC SYMPTOMS IN CHILDREN WITH CRANIOPHARYNGIOMA.

scientific article

EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY

article

Effect of cancer therapy on neural stem cells: implications for cognitive function

scientific article

Electrical and synaptic integration of glioma into neural circuits

scientific article published on 18 September 2019

Emerging mechanistic underpinnings and therapeutic targets for chemotherapy-related cognitive impairment

scientific article published on 01 November 2019

Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition

scientific article

Excitation-neurogenesis coupling in adult neural stem/progenitor cells

scientific article

Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas ⬇️

scientific article published on March 2, 2012

Extreme sensitivity of adult neurogenesis to low doses of X-irradiation.

scientific article

Free radicals are involved in the damage to protein synthesis after anoxia/aglycemia and NMDA exposure

scientific article published on 01 February 2000

Functional and structural differences in the hippocampus associated with memory deficits in adult survivors of acute lymphoblastic leukemia

scientific article published on 8 August 2012

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.

scientific article

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

scientific article (publication date: June 2015)

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.

scientific article

GC-21PSYCHIATRIC SYMPTOMS IN CHILDREN WITH SUPRASELLAR TUMORS.

scientific article published on 30 May 2016

GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas

scientific article published on 07 February 2022

Gene therapy effectiveness differs for neuronal survival and behavioral performance

scientific article published in April 2001

HG-04NEURONAL ACTIVITY-REGULATED SECRETION OF NEUROLIGIN-3 PROMOTES GLIOMA GROWTH.

scientific article published on 21 April 2015

HG-109CONTEMPORARY SURVIVAL ENDPOINTS: AN INTERNATIONAL DIFFUSE INTRINSIC PONTINE GLIOMA REGISTRY STUDY.

scientific article published on 30 May 2016

HG-110SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HEMISPHERIC AND MIDLINE HIGH-GRADE GLIOMAS.

scientific article published on 30 May 2016

HG-16CDK7 INHIBITION IN DIFFUSE INTRINSIC PONTINE GLIOMA.

scientific article published on 30 May 2016

HG-23BET INHIBITORS WORK SYNERGISTICALLY WITH PANOBINOSTAT IN TREATING DIFFUSE INTRINSIC PONTINE GLIOMA.

scientific article published on 30 May 2016

HG-72DIPG CELLS ESCAPE THE PONS EARLY DURING TUMOUR EVOLUTION.

scientific article published on 30 May 2016

HG-73SAFETY AND FEASIBILITY OF A MULTI-INSTITUTIONAL PHASE II TRIAL INCOPORATING BIOPSY AND MOLECULARLY DETERMINED TREATMENT OF CHILDREN AND YOUNG ADULTS WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPG).

scientific article published on 30 May 2016

HG-78SYNTHETIC LETHAL EPIGENETIC INTERACTIONS IN K27M MUTATED DIPG.

scientific article published on 30 May 2016

HG-97PAEDIATRIC GBM AND DIPG SUBCLONES CO-OPERATE TO PROMOTE TUMORIGENESIS.

scientific article published on 30 May 2016

HG-99A PATIENT-DERIVED PAEDIATRIC HIGH GRADE GLIOMA AND DIPG CELL CULTURE PANEL RECAPITULATING THE GENOTYPIC AND PHENOTYPIC DIVERSITY OF THE DISEASE.

scientific article published on 30 May 2016

HGG-20. NEURONAL ACTIVITY PROMOTES PEDIATRIC GLIOMA INVASION.

scientific article published on 31 May 2017

HGG-21. MALIGNANT SYNAPTIC PLASTICITY IN PEDIATRIC HIGH-GRADE GLIOMAS

article by Kathryn Taylor et al published 1 June 2021 in Neuro-Oncology

HGG-22. TARGETING NEURONAL ACTIVITY-REGULATED NEUROLIGIN-3 DEPENDENCY FOR HIGH-GRADE GLIOMA THERAPY.

scientific article published on 31 May 2017

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma

scientific article

Hedgehogs, flies, Wnts and MYCs: the time has come for many things in medulloblastoma.

scientific article

High Grade Gliomas and DIPG

scholarly article

Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State

scientific article published on 03 October 2019

Human pontine glioma cells can induce murine tumors

scientific article

IM-04DELTA-24-RDG AS AN ALTERNATIVE THERAPEUTIC TOOL FOR pHGG/DIPG.

scientific article published on 21 April 2015

IMMU-19. LSD1 MODULATES NK CELL IMMUNOTHERAPY THROUGH AN ONCO-IMMUNOGENIC GENE SIGNATURE IN DIPG

IMMU-32. NON-INFLAMMATORY EFFECT OF DIPG ON TUMOR-ASSOCIATED MICROGLIA

Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies.

scientific article

Inflaming glioma growth

scientific article published on 01 October 2019

Inflammatory Blockade Restores Adult Hippocampal Neurogenesis ⬇️

scientific article (publication date: 5 December 2003)

Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer’s model

scientific article published on 21 March 2022

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

scientific article published on 26 September 2017

International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma

scientific article published on 16 November 2018

Irradiation induces neural precursor-cell dysfunction

scientific article

Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors

scientific article published on 27 April 2020

Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment

scientific article published on 20 May 2019

ME-04SUBVENTRICULAR SPREAD OF DIFFUSE INTRINSIC PONTINE GLIOMA.

scientific article published in November 2014

ME-08NEURONS PROMOTE GLIOMA GROWTH IN AN ACTIVITY-DEPENDENT MANNER

scientific article published in November 2014

MR Imaging features of Diffuse Intrinsic Pontine Glioma (DIPG) and Relationship to Overall Survival: Report from the International DIPG Registry

scientific article published on 06 June 2020

Maladaptive myelination promotes generalized epilepsy progression

scientific article published on 02 May 2022

Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment

scientific article published on 06 December 2018

Monosynaptic tracing maps brain-wide afferent oligodendrocyte precursor cell connectivity

scientific article published on 18 October 2019

Myelin Plasticity and Nervous System Function

scientific article published on 01 July 2018

Myelin plasticity in the central nervous system

scientific article published on 14 August 2015

NCI-CONNECT: Comprehensive Oncology Network Evaluating Rare CNS Tumors-Histone Mutated Midline Glioma Workshop Proceedings

scientific article published on 16 January 2020

Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma

scientific article published on 12 August 2017

Neurological complications following treatment of children with brain tumors

scientific article published on January 2011

Neurological complications in adults

scientific article published on January 2009

Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion

scientific article (publication date: 7 May 2015)

Neuronal Activity in Ontogeny and Oncology

scientific article

Neuronal activity in the glioma microenvironment.

scientific article published on 30 October 2017

Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.

scientific article

Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1

scientific article published on 19 May 2022

Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma.

scientific article

Open questions: why are babies rarely born with cancer?

scientific article published on 01 November 2018

PDTM-29. TRANSCRIPTIONAL DEPENDENCIES IN DIFFUSE INTRINSIC PONTINE GLIOMA

PDTM-39. GD2-DIRECTED CHIMERIC ANTIGEN RECEPTOR T CELLS AS A POTENT IMMUNOTHERAPY REGIMEN IN XENOGRAFT MODELS OF DIFFUSE INTRINSIC PONTINE GLIOMA

PEDIATRICS LABORATORY RESEARCH

PM-04DECODING THE CELLULAR HETEROGENEITY OF PEDIATRIC HIGH GRADE GLIOMA.

scientific article published on 21 April 2015

PTPS-24MECHANISMS OF DIFFUSE INTRINSIC PONTINE GLIOMA METASTASIS TO THE SUBVENTRICULAR ZONE.

scientific article

Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma

scientific article published on 02 July 2021

Pediatric Brain Tumors

scientific article published on 01 December 2020

Pediatric high-grade glioma: biologically and clinically in need of new thinking

scientific article

Pharmacologic inhibition of lysine specific demethylase-1 (LSD1) as a therapeutic and immune-sensitization strategy in diffuse intrinsic pontine glioma (DIPG)

Pharmacologic inhibition of lysine specific demethylase-1 (LSD1) as a therapeutic and immune-sensitization strategy in pediatric high grade glioma (pHGG)

scientific article published on 13 March 2020

Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas.

scientific article published on 16 April 2018

Radiation injury and neurogenesis

scientific article

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

scientific article (publication date: May 2014)

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

scientific article

Roadmap for the Emerging Field of Cancer Neuroscience

scientific article published on 01 April 2020

STMC-01. OLIGODENDROCYTE PRECURSOR CELL HYPERCELLULARITY IN A MOUSE MODEL OF NEUROFIBROMATOSIS TYPE (NF1) RESEMBLES PRENEOPLASTIC LESIONS.

scientific article

Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG

scientific article published on 01 October 2020

Settling a Nervous Stomach: The Neural Regulation of Enteric Cancer

scientific article published on 01 January 2017

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

scientific article published on 2 November 2016

Subventricular spread of diffuse intrinsic pontine glioma

scientific article

Synaptic communication in brain cancer

scientific article published on 07 May 2020

TERT and DNMT1 expression predict sensitivity to decitabine in gliomas

scientific article published on 03 September 2020

THER-31. TARGETING THE HISTONE DEMETHYLASE LSD1 FOR SELECTIVE APOPTOSIS AND IMMUNE-SENSITIZATION IN PEDIATRIC DIPG

TMIC-09. EXCITATORY SYNAPSES BETWEEN PRESYNAPTIC NEURONS AND POSTSYNAPTIC GLIOMA CELLS PROMOTE GLIOMA PROGRESSION

scientific article published on 5 November 2018

Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.

scientific article published on 20 September 2017

The bright and the dark side of myelin plasticity: Neuron-glial interactions in health and disease

scientific article published on 05 December 2020

The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease.

scientific article

The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

scientific article published in 2022

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

scientific article published on 28 May 2019

Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening

scientific article published on 01 November 2019

Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma

scientific article published on 11 April 2017

Treating cancer therapy-related cognitive impairment

scientific article published on 30 July 2020

Understanding the Deadly Silence of Posterior Fossa A Ependymoma

scientific article published on 01 June 2020

Wrapped to Adapt: Experience-Dependent Myelination

scientific article

c-Jun overexpression in CAR T cells induces exhaustion resistance

scientific article published on 04 December 2019

List of works by Michelle Monje

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG).

A comparative study of brain tumor cells from different age and anatomical locations using 3D biomimetic hydrogels

ALK2 inhibitors display beneficial effects in preclinical models of mutant diffuse intrinsic pontine glioma

ANGIOGENESIS AND INVASION

Abstracts

Activity Shapes Neural Circuit Form and Function: A Historical Perspective

An Active Role for Neurons in Glioma Progression: Making Sense of Scherer's Structures.

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication

BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

BSTM-04. NEURONAL-ACTIVITY SECRETED BDNF INCREASES DIPG PROLIFERATION

BT-02FUNCTIONALLY-DEFINED THERAPEUTIC TARGETS IN DIFFUSE INTRINSIC PONTINE GLIOMA.

BT-05FUNCTIONAL DIVERSITY AND CO-OPERATIVITY OF SUBCLONAL POPULATIONS OF PAEDIATRIC GLIOBLASTOMA AND DIFFUSE INTRINSIC PONTINE GLIOMA CELLS.

Bad wrap: Myelin and myelin plasticity in health and disease

Bespoke myelin tailored to neuron type

Brain Perfusion and Diffusion Abnormalities in Children Treated for Posterior Fossa Brain Tumors

CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors

CBIO-48DECODING THE CELLULAR HETEROGENEITY OF MALIGNANT GLIOMA.

CELL BIOLOGY AND SIGNALING

CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma

Calbindin overexpression buffers hippocampal cultures from the energetic impairments caused by glutamate

Chemoradiation impairs normal developmental cortical thinning in medulloblastoma

Clinical patterns and biological correlates of cognitive dysfunction associated with cancer therapy

Cognitive side effects of cancer therapy demonstrate a functional role for adult neurogenesis

Complete ocular paresis in a child with posterior fossa syndrome

Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study

Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma

Cranial radiation therapy and damage to hippocampal neurogenesis

DIPG-03. EXCITATORY SYNAPSES BETWEEN PRESYNAPTIC NEURONS AND POSTSYNAPTIC GLIOMA CELLS PROMOTE DIPG PROGRESSION

DIPG-03. TARGETING PI3K USING THE BLOOD BRAIN BARRIER PENETRABLE INHIBITOR, GDC-0084, FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

DIPG-09. HDAC INHIBITION IN THALAMIC AND SPINAL CORD H3K27M+ DIFFUSE MIDLINE GLIOMA

DIPG-11. NEURAL PRECURSOR CELL:GLIOMA INTERACTIONS MEDIATE TUMOR COLONIZATION OF THE SUBVENTRICULAR ZONE BY DIPG.

DIPG-13. TRANSCRIPTIONAL DEPENDENCIES IN DIFFUSE INTRINSIC PONTINE GLIOMA.

DIPG-21. ELECTRICAL INTEGRATION OF GLIOMA INTO NEURAL CIRCUITRY

DIPG-22. A PHASE 1 TRIAL OF THE HISTONE DEACETYLASE INHIBITOR PANOBINOSTAT IN PEDIATRIC PATIENTS WITH RECURRENT OR REFRACTORY DIFFUSE INTRINSIC PONTINE GLIOMA: A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY

DIPG-22. IDENTIFICATION OF THERAPEUTIC TARGETS IN DIPGS USING LARGE-SCALE RNAI SCREENING.

DIPG-26. NON-INFLAMMATORY EFFECT OF DIPG ON TUMOR-ASSOCIATED MICROGLIA.

DIPG-27. OPTIMIZING CLINICAL TRIAL DESIGN: PHARMACOKINETICS OF MARIZOMIB AND PANOBINOSTAT IN A NON-HUMAN PRIMATE MODEL

DIPG-29. GENOMIC LANDSCAPE OF DIFFUSE INTRINSIC PONTINE GLIOMA: AN ANALYSIS OF THE DIPG-BATS COHORT.

DIPG-36. ANTI-GD2 CHIMERIC ANTIGEN RECEPTOR T CELLS AS A POTENT IMMUNOTHERAPY REGIMEN IN XENOGRAFT MODELS OF HISTONE 3 K27M MUTANT DIFFUSE MIDLINE GLIOMA.

DIPG-41. IDENTIFICATION OF BIRC5 AS A NOVEL THERAPEUTIC TARGET FOR DIFFUSE INTRINSIC PONTINE GLIOMA

DIPG-48. DIFFUSE INTRINSIC PONTINE GLIOMA CELLS ARE INTERCONNECTED BY ‘TUMOR MICROTUBES’

DIPG-52. ACTIVE CHROMATIN IN H3K27M DIPG REVEALS DISTINCT EPIGENETIC SUBTYPES AND SUBTYPE-SPECIFIC MECHANISMS OF PATHOGENESIS

DIPG-55. TARGETING SENESCENT CELLS WITH ABT-263 ENHANCES CELL DEATH INDUCED BY BMI1 INHIBITION AND IONIZING RADIATION IN DIPG

DIPG-69. CHARACTERISTICS OF PATIENTS ≥ 10 YEARS OF AGE WITH DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY

DIPG-70. CLINICAL, RADIOLOGICAL, PATHOLOGICAL AND MOLECULAR CHARACTERISTICS OF CHILDREN <3 YEARS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A REPORT FROM THE INTERNATIONAL DIPG REGISTRY

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

Developmental origins and emerging therapeutic opportunities for childhood cancer

Diffuse Intrinsic Pontine Glioma: From Diagnosis to Next-Generation Clinical Trials

Diffuse Intrinsic Pontine Glioma: New Pathophysiological Insights and Emerging Therapeutic Targets

Diffuse intrinsic pontine glioma: molecular landscape and emerging therapeutic targets

Diffusion-weighted MRI derived apparent diffusion coefficient identifies prognostically distinct subgroups of pediatric diffuse intrinsic pontine glioma

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors.

Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice

Durable response of a radiation-induced, high-grade cerebellar glioma to temozolomide.

EPID-12PSYCHIATRIC SYMPTOMS IN CHILDREN WITH CRANIOPHARYNGIOMA.

EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY

Effect of cancer therapy on neural stem cells: implications for cognitive function

Electrical and synaptic integration of glioma into neural circuits

Emerging mechanistic underpinnings and therapeutic targets for chemotherapy-related cognitive impairment

Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition

Excitation-neurogenesis coupling in adult neural stem/progenitor cells

Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas ⬇️

Extreme sensitivity of adult neurogenesis to low doses of X-irradiation.

Free radicals are involved in the damage to protein synthesis after anoxia/aglycemia and NMDA exposure

Functional and structural differences in the hippocampus associated with memory deficits in adult survivors of acute lymphoblastic leukemia

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.

GC-21PSYCHIATRIC SYMPTOMS IN CHILDREN WITH SUPRASELLAR TUMORS.

GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas

Gene therapy effectiveness differs for neuronal survival and behavioral performance

HG-04NEURONAL ACTIVITY-REGULATED SECRETION OF NEUROLIGIN-3 PROMOTES GLIOMA GROWTH.

HG-109CONTEMPORARY SURVIVAL ENDPOINTS: AN INTERNATIONAL DIFFUSE INTRINSIC PONTINE GLIOMA REGISTRY STUDY.

HG-110SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HEMISPHERIC AND MIDLINE HIGH-GRADE GLIOMAS.

HG-16CDK7 INHIBITION IN DIFFUSE INTRINSIC PONTINE GLIOMA.

HG-23BET INHIBITORS WORK SYNERGISTICALLY WITH PANOBINOSTAT IN TREATING DIFFUSE INTRINSIC PONTINE GLIOMA.

HG-72DIPG CELLS ESCAPE THE PONS EARLY DURING TUMOUR EVOLUTION.