List of works - Victor H Engelhard

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

scientific article published oln 16 November 2016

A Listeria monocytogenes pentapeptide is presented to cytolytic T lymphocytes by the H2-M3 MHC class Ib molecule.

scientific article

A naturally processed peptide presented by HLA-A*0201 is expressed at low abundance and recognized by an alloreactive CD8+ cytotoxic T cell with apparent high affinity.

scientific article

A single amino acid substitution in HLA-A2 can alter the selection of the cytotoxic T lymphocyte repertoire that responds to influenza virus matrix peptide 55-73.

scientific article published in July 1989

Activated CD8 T cells redistribute to antigen-free lymph nodes and exhibit effector and memory characteristics.

scientific article

Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation

scientific article

Alloreactive cytotoxic T lymphocytes focus on specific major histocompatibility complex-bound peptides

scientific article published on 01 July 1997

Antibiotics Drive Microbial Imbalance and Vitiligo Development in Mice

scientific article published on 28 August 2019

Antigen density presented by dendritic cells in vivo differentially affects the number and avidity of primary, memory, and recall CD8+ T cells.

scientific article

Antigens derived from melanocyte differentiation proteins: self-tolerance, autoimmunity, and use for cancer immunotherapy

scientific article

CD8 T cells activated in distinct lymphoid organs differentially express adhesion proteins and coexpress multiple chemokine receptors

scientific article

Cancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy.

scientific article

Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

scientific article published on March 6, 1992

Class I-restricted alloreactive cytotoxic T lymphocytes recognize a complex array of specific MHC-associated peptides.

scientific article published on February 1998

Comparative Transcriptomic Analysis Identifies a Range of Immunologically Related Functional Elaborations of Lymph Node Associated Lymphatic and Blood Endothelial Cells

scientific article published on 16 April 2019

Competition among peptides in melanoma vaccines for binding to MHC molecules

scientific article

Complete primary structure of human histocompatibility antigen HLA-B7: evolutionary and functional implications

scientific article published on 01 January 1980

Construction of novel class I histocompatibility antigens by interspecies exon shuffling.

scientific article published in June 1985

Control of CD8 T-Cell Infiltration into Tumors by Vasculature and Microenvironment

scientific article

Creating new peptide antigens by slicing and splicing proteins

scientific article

Cytotoxic T lymphocyte recognition of HLA-A/B antigens introduced into EL4 cells by cell-liposome fusion.

scientific article published in January 1984

Cytotoxic T lymphocyte-defined epitope differences between HLA-A2.1 and HLA-A2.2 map to two distinct regions of the molecule.

scientific article

Cytotoxic T lymphocytes from HLA-A2 transgenic mice specific for HLA-A2 expressed on human cells.

scientific article

Cytotoxic activity and lymphokine production of T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ cytotoxic T lymphocyte (CTL) clones recognizing HLA-A2 and HLA-A2 mutants. Recognition of TCR-gamma delta+ CTL clones is affected by mutations at

scientific article published on 01 June 1990

Demonstration of a calcium influx in cytolytic T lymphocytes in response to target cell binding

scientific article published on 01 January 1987

Dendritic cell immunization route determines integrin expression and lymphoid and nonlymphoid tissue distribution of CD8 T cells.

scientific article

Derivation of cytotoxic T cell lines that express T cell receptor but exhibit reversible loss of stable antigen binding

scientific article published on 01 November 1986

Determination of intronic sequences adjacent to an exon using polymerase chain reaction and genomic DNA library constructed by TA cloning.

scientific article

Differential Expression of Homing Receptor Ligands on Tumor-Associated Vasculature that Control CD8 Effector T-cell Entry.

scientific article published on 2 November 2017

Direct identification of an endogenous peptide recognized by multiple HLA-A2.1-specific cytotoxic T cells.

scientific article

Direct identification of tumor-associated peptide antigens.

scientific article

Disparity for a newly identified minor histocompatibility antigen, HA-8, correlates with acute graft-versus-host disease after haematopoietic stem cell transplantation from an HLA-identical sibling.

scientific article published in November 2003

Distinct role for CD8 T cells toward cutaneous tumors and visceral metastases

scientific article published on 01 January 2008

Diversity and dominance among TCR recognizing HLA-A2.1+ influenza matrix peptide in human MHC class I transgenic mice.

scientific article

Effect of membrane phospholipid compositional changes on adenylate cyclase in LM cells.

scientific article published on August 1978

Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity

scientific article

Enhanced in vitro potency and in vivo immunogenicity of a CTL epitope from hepatitis C virus core protein following amino acid replacement at secondary HLA-A2.1 binding positions

scientific article

Evaluation of peptide vaccine immunogenicity in draining lymph nodes and peripheral blood of melanoma patients.

scientific article

Fas-independent apoptosis of activated T cells induced by antibodies to the HLA class I alpha1 domain

scientific article published on 01 November 1997

Feasibility of using genetic linkage analysis to identify the genes encoding T cell-defined minor histocompatibility antigens.

scientific article

Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma

scientific article published on 06 August 2018

HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation

scientific article published on March 6, 1992

How cells process antigens.

scientific article

Human melanoma patients recognize an HLA-A1-restricted CTL epitope from tyrosinase containing two cysteine residues: implications for tumor vaccine development.

scientific article

Identification and Characterization of Complex Glycosylated Peptides Presented by the MHC Class II Processing Pathway in Melanoma.

scientific article

Identification and Characterization of Tertiary Lymphoid Structures in Murine Melanoma

scientific article published on 01 January 2018

Identification by mass spectrometry of CD8(+)-T-cell Mycobacterium tuberculosis epitopes within the Rv0341 gene product

scientific article

Identification by site-directed mutagenesis of amino acid residues contributing to serologic and CTL-defined epitope differences between HLA-A2.1 and HLA-A2.3.

scientific article published on 01 October 1988

Identification of a graft versus host disease-associated human minor histocompatibility antigen

scientific article published in Science

Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines.

scientific article

Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism.

scientific article

Identification of a shared epitope recognized by melanoma-specific, HLA-A3-restricted cytotoxic T lymphocytes

scientific article

Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy

scientific article published on 25 September 2006

Identification of endogenous peptides recognized by in vivo or in vitro generated alloreactive cytotoxic T lymphocytes: distinct characteristics correlated with CD8 dependence

scientific article published on 01 February 2001

Identification of novel and widely expressed cancer/testis gene isoforms that elicit spontaneous cytotoxic T-lymphocyte reactivity to melanoma

scientific article

Immune Cell Infiltration and Tertiary Lymphoid Structures as Determinants of Antitumor Immunity

scientific article published in January 2018

Immune responses in a mouse model of vitiligo with spontaneous epidermal de- and repigmentation.

scientific article

Immune responses to the HLA-A0201-restricted epitopes of tyrosinase and glycoprotein 100 enable control of melanoma outgrowth in HLA-A0201-transgenic mice.

scientific article

Immunity to melanoma antigens: from self-tolerance to immunotherapy

scientific article

Importance of MHC class 1 alpha2 and alpha3 domains in the recognition of self and non-self MHC molecules.

scientific article

Induction of secondary cytotoxic T lymphocytes by liposomes containing HLA-DR antigens.

scientific article published in January 1980

Induction of secondary cytotoxic T lymphocytes by purified HLA-A and HLA-B antigens reconstituted into phospholipid vesicles ⬇️

scientific article published on November 1, 1978

Influenza A-specific, HLA-A2.1-restricted cytotoxic T lymphocytes from HLA-A2.1 transgenic mice recognize fragments of the M1 protein ⬇️

scientific article published on February 15, 1991

Inhibition of T cell activation by a monoclonal antibody reactive against the alpha 3 domain of human MHC class I molecules

scientific article published on 01 August 1994

Insights into antigen processing gained by direct analysis of the naturally processed class I MHC associated peptide repertoire

scientific article

Introduction of HLA-A/B antigens into lymphoid cell membranes by cell-liposome fusion

scientific article published on 01 January 1984

Isolation and characterization of monoclonal mouse cytotoxic T lymphocytes with specificity for HLA-A,B or -DR alloantigens

scientific article published on 01 December 1982

Limited infiltration of exogenous dendritic cells and naive T cells restricts immune responses in peripheral lymph nodes.

scientific article

Lipopeptide-based melanoma cancer vaccine induced a strong MART-27-35-cytotoxic T lymphocyte response in a preclinal study.

scientific article published on March 2002

Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

scientific article

Lymphatic endothelial cells - key players in regulation of tolerance and immunity

scientific article

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

scientific article

MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia.

scientific article

MHC class II presentation of gp100 epitopes in melanoma cells requires the function of conventional endosomes and is influenced by melanosomes.

scientific article

MHC-restricted phosphopeptide antigens: preclinical validation and first-in-humans clinical trial in participants with high-risk melanoma

scientific article published on 01 May 2020

MHC-restricted phosphopeptides from insulin receptor substrate-2 and CDC25b offer broad-based immunotherapeutic agents for cancer

scientific article

Mass-spectrometric evaluation of HLA-A*0201-associated peptides identifies dominant naturally processed forms of CTL epitopes from MART-1 and gp100.

scientific article

Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase-specific TCR transgenic mice

scientific article

Melanomas with concordant loss of multiple melanocytic differentiation proteins: immune escape that may be overcome by targeting unique or undefined antigens.

scientific article

Modification of adenylate cyclase activity in LM cells by manipulation of the membrane phospholipid composition in vivo ⬇️

scientific article published on December 1, 1976

Multiple epitopes on human and murine cells expressing HLA-B7 as defined by specific murine cytotoxic T cell clones

scientific article published on 01 August 1985

N-glycosylation enhances presentation of a MHC class I-restricted epitope from tyrosinase

scientific article

Negative cooperativity exhibited by prostaglandin E1 stimulated adenylate cyclase in LM cells

scientific article published on November 28, 1978

Patterns of immune-cell infiltration in murine models of melanoma: roles of antigen and tissue site in creating inflamed tumors

scientific article published on 27 May 2019

Peptide and dendritic cell vaccines

scientific article

Perforin-dependent cytotoxic activity and lymphokine secretion by CD4+ T cells are regulated by CD8+ T cells ⬇️

scientific article published on September 1, 1997

Peripheral tissue homing receptor control of naïve, effector, and memory CD8 T cell localization in lymphoid and non-lymphoid tissues

scientific article

Peripheral tissue homing receptors enable T cell entry into lymph nodes and affect the anatomical distribution of memory cells

scientific article

Phase I trial of a melanoma vaccine with gp100(280-288) peptide and tetanus helper peptide in adjuvant: immunologic and clinical outcomes.

scientific article

Phosphorylated peptides are naturally processed and presented by major histocompatibility complex class I molecules in vivo

scientific article

Post-translational modifications of naturally processed MHC-binding epitopes

scientific article

Preventing the spontaneous modification of an HLA-A2-restricted peptide at an N-terminal glutamine or an internal cysteine residue enhances peptide antigenicity

scientific article

Prevention of diabetes in BB rats. I. Evidence suggesting a requirement for mature T cells in bone marrow inoculum of neonatally injected rats

scientific article published on 01 September 1986

Prevention of diabetes in the BB rat by injection of major histocompatibility complex- (MHC-) compatible bone marrow cells.

scientific article

Probing HLA-B7 conformational shifts induced by peptide-binding groove mutations and bound peptide with anti-HLA monoclonal antibodies.

scientific article published on September 1996

Processing of a class I-restricted epitope from tyrosinase requires peptide N-glycanase and the cooperative action of endoplasmic reticulum aminopeptidase 1 and cytosolic proteases.

scientific article

Production of cyclic AMP from extracellular ATP by intact LM cells ⬇️

scientific article published on February 19, 1979

Prophylactic DNA vaccine for hepatitis C virus (HCV) infection: HCV-specific cytotoxic T lymphocyte induction and protection from HCV-recombinant vaccinia infection in an HLA-A2.1 transgenic mouse model.

retracted scientific article

Recognition of human melanoma cells by HLA-A2.1-restricted cytotoxic T lymphocytes is mediated by at least six shared peptide epitopes ⬇️

scientific article published on April 1, 1993

Reconstitution of purified detergent-soluble HLA-A and HLA-B antigens into phospholipid vesicles ⬇️

scientific article published on July 1, 1978

Regulated folding of tyrosinase in the endoplasmic reticulum demonstrates that misfolded full-length proteins are efficient substrates for class I processing and presentation.

scientific article

Regulation of T-cell Tolerance by Lymphatic Endothelial Cells.

scientific article

Regulatory T cells and vasectomy

scientific article

Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity

scientific article

Reorientation and fusion of cytotoxic T lymphocyte granules after interaction with target cells as determined by high resolution cinemicrography

scientific article published on 01 January 1986

Retraction

scientific article published on 01 May 2001

Role of endogenous peptide in human alloreactive cytotoxic T cell responses

scientific article published on March 1, 1992

Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction

scientific article

Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control

scientific article

Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition.

scientific article

Self-tolerance to the murine homologue of a tyrosinase-derived melanoma antigen: implications for tumor immunotherapy

scientific article

Several HLA alleles share overlapping peptide specificities.

scientific article published on January 1995

Species specificity and augmentation of responses to class II major histocompatibility complex molecules in human CD4 transgenic mice ⬇️

scientific article published on June 1, 1992

Species specificity in the interaction of CD8 with the alpha 3 domain of MHC class I molecules ⬇️

scientific article published on July 1, 1992

Specificity of mouse cytotoxic T lymphocytes stimulated with either HLA-A and -B or HLA-DR antigens reconstituted into phospholipid vesicles

scientific article published on 01 August 1980

Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720

scientific journal article

Strategies and challenges in eliciting immunity to melanoma

scientific article

Structural basis for the presentation of tumor-associated MHC class II-restricted phosphopeptides to CD4+ T cells

scientific article

Structure of peptides associated with MHC class I molecules.

scientific article

Subcellular location of adenylate cyclase in rat cardiac muscle ⬇️

scientific article published on November 18, 1976

Tapasin is a facilitator, not an editor, of class I MHC peptide binding.

scientific article

Targeting Fel d 1 to FcgammaRI induces a novel variation of the T(H)2 response in subjects with cat allergy.

scientific article

Targeting allergen to FcgammaRI reveals a novel T(H)2 regulatory pathway linked to thymic stromal lymphopoietin receptor.

scientific article

Terminal modifications inhibit proteolytic degradation of an immunogenic MART-1(27-35) peptide: implications for peptide vaccines.

scientific article

The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein.

scientific article

The PANE1 gene encodes a novel human minor histocompatibility antigen that is selectively expressed in B-lymphoid cells and B-CLL.

scientific article

The ability of cytotoxic T cells to recognize HLA-A2.1 or HLA-B7 antigens expressed on murine cells correlates with their epitope specificity.

scientific article

The contributions of mass spectrometry to understanding of immune recognition by T lymphocytes

scientific article

The immunodominant antigen of an ultraviolet-induced regressor tumor is generated by a somatic point mutation in the DEAD box helicase p68

scientific article

The minor histocompatibility antigen HA-1: a diallelic gene with a single amino acid polymorphism.

scientific article

The minor histocompatibility antigen HA-3 arises from differential proteasome-mediated cleavage of the lymphoid blast crisis (Lbc) oncoprotein

scientific article (publication date: 15 July 2003)

The peptide recognized by HLA-A68.2-restricted, squamous cell carcinoma of the lung-specific cytotoxic T lymphocytes is derived from a mutated elongation factor 2 gene.

scientific article published on November 1998

The role of K+ in the regulation of the increase in intracellular Ca2+ mediated by the T lymphocyte antigen receptor

scientific article published on 01 July 1987

Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment

scientific article

Tumor masses support naive T cell infiltration, activation, and differentiation into effectors

scientific article

Tyrosinase degradation via two pathways during reverse translocation to the cytosol.

scientific article published in July 2001

Xenogeneic cytotoxic T-cell clones recognize alloantigenic determinants on HLA-A2 ⬇️

scientific article published on January 1, 1983

List of works by Victor H Engelhard

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

A Listeria monocytogenes pentapeptide is presented to cytolytic T lymphocytes by the H2-M3 MHC class Ib molecule.

A naturally processed peptide presented by HLA-A*0201 is expressed at low abundance and recognized by an alloreactive CD8+ cytotoxic T cell with apparent high affinity.

A single amino acid substitution in HLA-A2 can alter the selection of the cytotoxic T lymphocyte repertoire that responds to influenza virus matrix peptide 55-73.

Activated CD8 T cells redistribute to antigen-free lymph nodes and exhibit effector and memory characteristics.

Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation

Alloreactive cytotoxic T lymphocytes focus on specific major histocompatibility complex-bound peptides

Antibiotics Drive Microbial Imbalance and Vitiligo Development in Mice

Antigen density presented by dendritic cells in vivo differentially affects the number and avidity of primary, memory, and recall CD8+ T cells.

Antigens derived from melanocyte differentiation proteins: self-tolerance, autoimmunity, and use for cancer immunotherapy

CD8 T cells activated in distinct lymphoid organs differentially express adhesion proteins and coexpress multiple chemokine receptors

Cancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy.

Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

Class I-restricted alloreactive cytotoxic T lymphocytes recognize a complex array of specific MHC-associated peptides.

Comparative Transcriptomic Analysis Identifies a Range of Immunologically Related Functional Elaborations of Lymph Node Associated Lymphatic and Blood Endothelial Cells

Competition among peptides in melanoma vaccines for binding to MHC molecules

Complete primary structure of human histocompatibility antigen HLA-B7: evolutionary and functional implications

Construction of novel class I histocompatibility antigens by interspecies exon shuffling.

Control of CD8 T-Cell Infiltration into Tumors by Vasculature and Microenvironment

Creating new peptide antigens by slicing and splicing proteins

Cytotoxic T lymphocyte recognition of HLA-A/B antigens introduced into EL4 cells by cell-liposome fusion.

Cytotoxic T lymphocyte-defined epitope differences between HLA-A2.1 and HLA-A2.2 map to two distinct regions of the molecule.

Cytotoxic T lymphocytes from HLA-A2 transgenic mice specific for HLA-A2 expressed on human cells.

Cytotoxic activity and lymphokine production of T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ cytotoxic T lymphocyte (CTL) clones recognizing HLA-A2 and HLA-A2 mutants. Recognition of TCR-gamma delta+ CTL clones is affected by mutations at

Demonstration of a calcium influx in cytolytic T lymphocytes in response to target cell binding

Dendritic cell immunization route determines integrin expression and lymphoid and nonlymphoid tissue distribution of CD8 T cells.

Derivation of cytotoxic T cell lines that express T cell receptor but exhibit reversible loss of stable antigen binding

Determination of intronic sequences adjacent to an exon using polymerase chain reaction and genomic DNA library constructed by TA cloning.

Differential Expression of Homing Receptor Ligands on Tumor-Associated Vasculature that Control CD8 Effector T-cell Entry.

Direct identification of an endogenous peptide recognized by multiple HLA-A2.1-specific cytotoxic T cells.

Direct identification of tumor-associated peptide antigens.

Disparity for a newly identified minor histocompatibility antigen, HA-8, correlates with acute graft-versus-host disease after haematopoietic stem cell transplantation from an HLA-identical sibling.

Distinct role for CD8 T cells toward cutaneous tumors and visceral metastases

Diversity and dominance among TCR recognizing HLA-A2.1+ influenza matrix peptide in human MHC class I transgenic mice.

Effect of membrane phospholipid compositional changes on adenylate cyclase in LM cells.

Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity

Enhanced in vitro potency and in vivo immunogenicity of a CTL epitope from hepatitis C virus core protein following amino acid replacement at secondary HLA-A2.1 binding positions

Evaluation of peptide vaccine immunogenicity in draining lymph nodes and peripheral blood of melanoma patients.

Fas-independent apoptosis of activated T cells induced by antibodies to the HLA class I alpha1 domain

Feasibility of using genetic linkage analysis to identify the genes encoding T cell-defined minor histocompatibility antigens.

Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma

HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation

How cells process antigens.

Human melanoma patients recognize an HLA-A1-restricted CTL epitope from tyrosinase containing two cysteine residues: implications for tumor vaccine development.

Identification and Characterization of Complex Glycosylated Peptides Presented by the MHC Class II Processing Pathway in Melanoma.

Identification and Characterization of Tertiary Lymphoid Structures in Murine Melanoma

Identification by mass spectrometry of CD8(+)-T-cell Mycobacterium tuberculosis epitopes within the Rv0341 gene product

Identification by site-directed mutagenesis of amino acid residues contributing to serologic and CTL-defined epitope differences between HLA-A2.1 and HLA-A2.3.

Identification of a graft versus host disease-associated human minor histocompatibility antigen

Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines.

Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism.

Identification of a shared epitope recognized by melanoma-specific, HLA-A3-restricted cytotoxic T lymphocytes

Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy

Identification of endogenous peptides recognized by in vivo or in vitro generated alloreactive cytotoxic T lymphocytes: distinct characteristics correlated with CD8 dependence

Identification of novel and widely expressed cancer/testis gene isoforms that elicit spontaneous cytotoxic T-lymphocyte reactivity to melanoma

Immune Cell Infiltration and Tertiary Lymphoid Structures as Determinants of Antitumor Immunity

Immune responses in a mouse model of vitiligo with spontaneous epidermal de- and repigmentation.

Immune responses to the HLA-A*0201-restricted epitopes of tyrosinase and glycoprotein 100 enable control of melanoma outgrowth in HLA-A*0201-transgenic mice.

Immunity to melanoma antigens: from self-tolerance to immunotherapy

Importance of MHC class 1 alpha2 and alpha3 domains in the recognition of self and non-self MHC molecules.

Induction of secondary cytotoxic T lymphocytes by liposomes containing HLA-DR antigens.

Induction of secondary cytotoxic T lymphocytes by purified HLA-A and HLA-B antigens reconstituted into phospholipid vesicles ⬇️

Influenza A-specific, HLA-A2.1-restricted cytotoxic T lymphocytes from HLA-A2.1 transgenic mice recognize fragments of the M1 protein ⬇️

Inhibition of T cell activation by a monoclonal antibody reactive against the alpha 3 domain of human MHC class I molecules

Insights into antigen processing gained by direct analysis of the naturally processed class I MHC associated peptide repertoire

Introduction of HLA-A/B antigens into lymphoid cell membranes by cell-liposome fusion

Isolation and characterization of monoclonal mouse cytotoxic T lymphocytes with specificity for HLA-A,B or -DR alloantigens

Limited infiltration of exogenous dendritic cells and naive T cells restricts immune responses in peripheral lymph nodes.

Lipopeptide-based melanoma cancer vaccine induced a strong MART-27-35-cytotoxic T lymphocyte response in a preclinal study.

Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

Lymphatic endothelial cells - key players in regulation of tolerance and immunity

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia.

MHC class II presentation of gp100 epitopes in melanoma cells requires the function of conventional endosomes and is influenced by melanosomes.

MHC-restricted phosphopeptide antigens: preclinical validation and first-in-humans clinical trial in participants with high-risk melanoma

MHC-restricted phosphopeptides from insulin receptor substrate-2 and CDC25b offer broad-based immunotherapeutic agents for cancer

Mass-spectrometric evaluation of HLA-A*0201-associated peptides identifies dominant naturally processed forms of CTL epitopes from MART-1 and gp100.

Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase-specific TCR transgenic mice

Melanomas with concordant loss of multiple melanocytic differentiation proteins: immune escape that may be overcome by targeting unique or undefined antigens.

Immune responses to the HLA-A0201-restricted epitopes of tyrosinase and glycoprotein 100 enable control of melanoma outgrowth in HLA-A0201-transgenic mice.