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List of works by Markos Koutmos

Antivitamin B12 Inhibition of the Human B12 -Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate

scientific article

Autoinhibition and Signaling by the Switch II Motif in the G-protein Chaperone of a Radical B12 Enzyme

scientific article

Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase

scientific article

Borohydride, azide, and chloride anions as terminal ligands on Fe/Mo/S clusters. Synthesis, structure and characterization of [(Cl4-cat)(PPr3) MoFe3S4(X)2]2(Bu4N)4 and [(Cl4-cat)(PPr3)MoFe3S4 (PPr3)(X)]2(Bu4N)2 (X = N3-, BH4-, Cl-) double-fused cuba

scientific article published on 01 May 2006

Differential substrate recognition by isozymes of plant protein-only Ribonuclease P

scientific article published on 10 March 2016

Dynamics of an [Fe4S4(SPh)4]2- cluster explored via IR, Raman, and nuclear resonance vibrational spectroscopy (NRVS)-analysis using 36S substitution, DFT calculations, and empirical force fields.

scientific article published on 9 February 2006

Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes

scientific article (publication date: 2015)

Insights into the reactivation of cobalamin-dependent methionine synthase

scientific article

Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair

scientific article published on 01 November 2019

Loss of the mitochondrial protein-only ribonuclease P complex causes aberrant tRNA processing and lethality in Drosophila

scientific article published on 30 April 2016

Metal active site elasticity linked to activation of homocysteine in methionine synthases

scientific article

Metal clusters as ligands. Substitution of fe ions in Fe/Mo/S clusters by thiophilic CuI ions

scientific article published on 01 February 2006

Metal clusters as ligands: substitution of Fe ions in Fe/Mo/S clusters by thiophilic Cu(I) ions to give clusters with [Cu4Mo2Fe2S8]4+ and [Cu5Mo3Fe4S11]6+ cores

scientific article published on 01 March 2005

Mitochondrial ribonuclease P structure provides insight into the evolution of catalytic strategies for precursor-tRNA 5' processing

scientific article

Mobile loop dynamics in adenosyltransferase control binding and reactivity of coenzyme B12

scientific article published on 16 November 2020

Molecular recognition of pre-tRNA by Arabidopsis protein-only Ribonuclease P.

scientific article published on 5 September 2017

Normal-mode analysis of FeCl4- and Fe2S2Cl42- via vibrational mössbauer, resonance Raman, and FT-IR spectroscopies.

scientific article published in August 2005

Nuclear Protein-Only Ribonuclease P2 Structure and Biochemical Characterization Provide Insight into the Conserved Properties of tRNA 5' End Processing Enzymes.

scientific article published on 3 December 2015

RNase P enzymes: divergent scaffolds for a conserved biological reaction.

scientific article published on April 2013

Rational synthesis of high nuclearity Mo/Fe/S clusters: the reductive coupling approach in the convenient synthesis of (Cl(4)-cat)(2)Mo(2)Fe(6)S(8)(PR(3))(6) [R = Et, (n)Pr, (n)Bu] and the new [(Cl(4)-cat)(2)Mo(2)Fe(2)S(3)O(PEt(3))(3)Cl]-1/2(Fe(PEt(

scientific article published on 01 November 2001

Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase

scientific article

Splicing variants of the porcine betaine-homocysteine S-methyltransferase gene: implications for mammalian metabolism.

scientific article published on 13 August 2013

Structural Basis of Multifunctionality in a Vitamin B12-processing Enzyme

scientific article

Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine  -synthase

scientific article

Structure of Human B12 Trafficking Protein CblD Reveals Molecular Mimicry and Identifies a New Subfamily of Nitro-FMN Reductases

scientific article

Superclusters: a host-guest complex with a cyclic array of three bridged MoFe3S4 clusters

scientific article published on 01 September 2004

Systematic synthesis of heterometallic Ni/Fe/S and Cu/Fe/S clusters with a pentlandite-like M8S6 core

scientific article published on 01 March 2005

The folate-binding module of Thermus thermophilus cobalamin-dependent methionine synthase displays a distinct variation of the classical TIM barrel: a TIM barrel with a `twist'.

scientific article