List of works - Edward A Botchwey

Abluminal stimulation of sphingosine 1-phosphate receptors 1 and 3 promotes and stabilizes endothelial sprout formation

scientific article

Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD.

scientific article

Advances in Local Drug Release and Scaffolding Design to Enhance Cell Therapy for Diabetes

scientific article

Alignment and composition of laminin-polycaprolactone nanofiber blends enhance peripheral nerve regeneration

scientific article

An engineered macroencapsulation membrane releasing FTY720 to precondition pancreatic islet transplantation.

scientific article

Aspirin-Triggered Resolvin D1-modified materials promote the accumulation of pro-regenerative immune cell subsets and enhance vascular remodeling

scientific article

Bioactive lipid coating of bone allografts directs engraftment and fate determination of bone marrow-derived cells in rat GFP chimeras

scientific article

Bioreactor-based bone tissue engineering: the influence of dynamic flow on osteoblast phenotypic expression and matrix mineralization

scientific article

Collagen nanofibres are a biomimetic substrate for the serum-free osteogenic differentiation of human adipose stem cells

scientific article

Comparative effects of scaffold pore size, pore volume, and total void volume on cranial bone healing patterns using microsphere-based scaffolds

scientific article

Delivery of S1P receptor‐targeted drugs via biodegradable polymer scaffolds enhances bone regeneration in a critical size cranial defect ⬇️

scientific article published on October 17, 2013

Delivery of bioactive lipids from composite microgel-microsphere injectable scaffolds enhances stem cell recruitment and skeletal repair

scientific article

Dual Affinity Heparin-Based Hydrogels Achieve Pro-Regenerative Immunomodulation and Microvascular Remodeling.

scientific article published on 20 February 2017

Emerging ideas: treatment of precollapse osteonecrosis using stem cells and growth factors

scientific article

Engineering in vivo gradients of sphingosine-1-phosphate receptor ligands for localized microvascular remodeling and inflammatory cell positioning

scientific article

Engineering vascularized tissues using natural and synthetic small molecules

scientific article

Enhanced osseous integration of human trabecular allografts following surface modification with bioactive lipids

scientific article

Enrichment of endogenous fractalkine and anti-inflammatory cells via aptamer-functionalized hydrogels

scientific article published on 10 July 2017

Erratum to: Enhanced osseous integration of human trabecular allografts following surface modification with bioactive lipids

scientific article

Evaluating Angiogenic Potential of Small Molecules Using Genetic Network Approaches

Evaluation of angiogenesis and osteogenesis

scientific article

Expansion of microvascular networks in vivo by phthalimide neovascular factor 1 (PNF1)

scientific article

FTY720 promotes local microvascular network formation and regeneration of cranial bone defects

scientific article

Harnessing lipid signaling pathways to target specialized pro-angiogenic neutrophil subsets for regenerative immunotherapy

scientific article published on 30 October 2020

Harnessing systems biology approaches to engineer functional microvascular networks

scientific article

Human osteoblast-like cells in three-dimensional culture with fluid flow.

scientific article published in January 2003

Immunotherapy via PD-L1-presenting biomaterials leads to long-term islet graft survival

scientific article published on 28 August 2020

Influence of poly(D,L-lactic-co-glycolic acid) microsphere degradation on arteriolar remodeling in the mouse dorsal skinfold window chamber

scientific article

Integrin-specific hydrogels modulate transplanted human bone marrow-derived mesenchymal stem cell survival, engraftment, and reparative activities

scientific article published on 08 January 2020

Laminin nanofiber meshes that mimic morphological properties and bioactivity of basement membranes

scientific article

Laminin- and basement membrane-polycaprolactone blend nanofibers as a scaffold for regenerative medicine

scientific article

Local delivery of FTY720 accelerates cranial allograft incorporation and bone formation ⬇️

scientific article published on August 24, 2011

Mechanistic exploration of phthalimide neovascular factor 1 using network analysis tools

scientific article

Modulating local S1P Receptor signaling as a regenerative immunotherapy after volumetric muscle loss injury

scientific article published on 30 June 2020

Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design

scientific article published on May 2016

Multilayer cell-seeded polymer nanofiber constructs for soft-tissue reconstruction

scientific article

Nanomedicine: Addressing Cardiovascular Disease and Cardiovascular Tissue Regeneration.

scientific article

Non-classical monocytes are biased progenitors of wound healing macrophages during soft tissue injury.

scientific article

Novel Lipid Signaling Mediators for Mesenchymal Stem Cell Mobilization during Bone Repair

Novel pathway compendium analysis elucidates mechanism of pro-angiogenic synthetic small molecule

scientific article

Phthalimide neovascular factor 1 (PNF1) modulates MT1-MMP activity in human microvascular endothelial cells

scientific article

Quantitative analysis of three-dimensional fluid flow in rotating bioreactors for tissue engineering

scientific article

Regulation of Angiogenesis and Bone Regeneration with Natural and Synthetic Small Molecules ⬇️

scientific article published on January 1, 2013

Regulation of osteoclast structure and function by FAK family kinases ⬇️

scientific article published on August 31, 2012

Selective Activation of Sphingosine 1-Phosphate Receptors 1 and 3 Promotes Local Microvascular Network Growth ⬇️

scientific article published on November 9, 2010

Selective recruitment of non-classical monocytes promotes skeletal muscle repair

scientific article published on 16 November 2016

Sickle cell disease promotes sex-dependent pathological bone loss through enhanced cathepsin proteolytic activity in mice

scientific article published on 01 March 2022

Small molecule inducers of angiogenesis for tissue engineering

scientific article

Spatiotemporal oxygen sensing using dual emissive boron dye-polylactide nanofibers

scientific article

Sphingosine-1-Phosphate Receptor-3 Supports Hematopoietic Stem and Progenitor Cell Residence Within the Bone Marrow Niche

scientific article

Sustained release of sphingosine 1-phosphate for therapeutic arteriogenesis and bone tissue engineering

scientific article

The enhancement of bone allograft incorporation by the local delivery of the sphingosine 1-phosphate receptor targeted drug FTY720.

scientific article

The promotion of mandibular defect healing by the targeting of S1P receptors and the recruitment of alternatively activated macrophages

scientific article

Tissue engineered bone: Measurement of nutrient transport in three‐dimensional matrices ⬇️

scientific article published on October 1, 2003

Xylan hemicellulose improves chitosan hydrogel for bone tissue regeneration

scientific article

List of works by Edward A Botchwey

Abluminal stimulation of sphingosine 1-phosphate receptors 1 and 3 promotes and stabilizes endothelial sprout formation

Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD.

Advances in Local Drug Release and Scaffolding Design to Enhance Cell Therapy for Diabetes

Alignment and composition of laminin-polycaprolactone nanofiber blends enhance peripheral nerve regeneration

An engineered macroencapsulation membrane releasing FTY720 to precondition pancreatic islet transplantation.

Aspirin-Triggered Resolvin D1-modified materials promote the accumulation of pro-regenerative immune cell subsets and enhance vascular remodeling

Bioactive lipid coating of bone allografts directs engraftment and fate determination of bone marrow-derived cells in rat GFP chimeras

Bioreactor-based bone tissue engineering: the influence of dynamic flow on osteoblast phenotypic expression and matrix mineralization

Collagen nanofibres are a biomimetic substrate for the serum-free osteogenic differentiation of human adipose stem cells

Comparative effects of scaffold pore size, pore volume, and total void volume on cranial bone healing patterns using microsphere-based scaffolds

Delivery of S1P receptor‐targeted drugs via biodegradable polymer scaffolds enhances bone regeneration in a critical size cranial defect ⬇️

Delivery of bioactive lipids from composite microgel-microsphere injectable scaffolds enhances stem cell recruitment and skeletal repair

Dual Affinity Heparin-Based Hydrogels Achieve Pro-Regenerative Immunomodulation and Microvascular Remodeling.

Emerging ideas: treatment of precollapse osteonecrosis using stem cells and growth factors

Engineering in vivo gradients of sphingosine-1-phosphate receptor ligands for localized microvascular remodeling and inflammatory cell positioning

Engineering vascularized tissues using natural and synthetic small molecules

Enhanced osseous integration of human trabecular allografts following surface modification with bioactive lipids

Enrichment of endogenous fractalkine and anti-inflammatory cells via aptamer-functionalized hydrogels

Erratum to: Enhanced osseous integration of human trabecular allografts following surface modification with bioactive lipids

Evaluating Angiogenic Potential of Small Molecules Using Genetic Network Approaches

Evaluation of angiogenesis and osteogenesis

Expansion of microvascular networks in vivo by phthalimide neovascular factor 1 (PNF1)

FTY720 promotes local microvascular network formation and regeneration of cranial bone defects

Harnessing lipid signaling pathways to target specialized pro-angiogenic neutrophil subsets for regenerative immunotherapy

Harnessing systems biology approaches to engineer functional microvascular networks

Human osteoblast-like cells in three-dimensional culture with fluid flow.

Immunotherapy via PD-L1-presenting biomaterials leads to long-term islet graft survival

Influence of poly(D,L-lactic-co-glycolic acid) microsphere degradation on arteriolar remodeling in the mouse dorsal skinfold window chamber

Integrin-specific hydrogels modulate transplanted human bone marrow-derived mesenchymal stem cell survival, engraftment, and reparative activities

Laminin nanofiber meshes that mimic morphological properties and bioactivity of basement membranes

Laminin- and basement membrane-polycaprolactone blend nanofibers as a scaffold for regenerative medicine

Local delivery of FTY720 accelerates cranial allograft incorporation and bone formation ⬇️

Mechanistic exploration of phthalimide neovascular factor 1 using network analysis tools

Modulating local S1P Receptor signaling as a regenerative immunotherapy after volumetric muscle loss injury

Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design

Multilayer cell-seeded polymer nanofiber constructs for soft-tissue reconstruction

Nanomedicine: Addressing Cardiovascular Disease and Cardiovascular Tissue Regeneration.

Non-classical monocytes are biased progenitors of wound healing macrophages during soft tissue injury.

Novel Lipid Signaling Mediators for Mesenchymal Stem Cell Mobilization during Bone Repair

Novel pathway compendium analysis elucidates mechanism of pro-angiogenic synthetic small molecule

Phthalimide neovascular factor 1 (PNF1) modulates MT1-MMP activity in human microvascular endothelial cells

Quantitative analysis of three-dimensional fluid flow in rotating bioreactors for tissue engineering

Regulation of Angiogenesis and Bone Regeneration with Natural and Synthetic Small Molecules ⬇️

Regulation of osteoclast structure and function by FAK family kinases ⬇️

Selective Activation of Sphingosine 1-Phosphate Receptors 1 and 3 Promotes Local Microvascular Network Growth ⬇️

Selective recruitment of non-classical monocytes promotes skeletal muscle repair

Sickle cell disease promotes sex-dependent pathological bone loss through enhanced cathepsin proteolytic activity in mice

Small molecule inducers of angiogenesis for tissue engineering

Spatiotemporal oxygen sensing using dual emissive boron dye-polylactide nanofibers

Sphingosine-1-Phosphate Receptor-3 Supports Hematopoietic Stem and Progenitor Cell Residence Within the Bone Marrow Niche

Sustained release of sphingosine 1-phosphate for therapeutic arteriogenesis and bone tissue engineering

The enhancement of bone allograft incorporation by the local delivery of the sphingosine 1-phosphate receptor targeted drug FTY720.

The promotion of mandibular defect healing by the targeting of S1P receptors and the recruitment of alternatively activated macrophages

Tissue engineered bone: Measurement of nutrient transport in three‐dimensional matrices ⬇️

Xylan hemicellulose improves chitosan hydrogel for bone tissue regeneration