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List of works by Sahil Seth

A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases

scientific article published on 01 July 2018

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

scientific article published on 8 May 2017

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

scientific article

A functional genomic approach to actionable gene fusions for precision oncology

scientific article published on 09 February 2022

Allosteric SHP2 inhibitor IACS-13909 overcomes EGFR-dependent and EGFR-independent resistance mechanisms towards osimertinib

scientific article published on 14 September 2020

Characterization of HPV and host genome interactions in primary head and neck cancers

scientific article

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma

scientific article published on 23 April 2018

Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.

scientific article

Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation

scientific article published on 01 January 2019

Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer

scientific article published on 3 March 2015

Global impact of somatic structural variation on the DNA methylome of human cancers

scientific article published on 15 October 2019

High-resolution clonal mapping of multi-organ metastasis in triple negative breast cancer

scientific article published in Nature Communications

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

scientific article published in October 2014

In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.

scientific article published on 16 June 2016

Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma

scientific article published on 26 May 2021

Mutational landscape of aggressive cutaneous squamous cell carcinoma

scientific article

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

scientific article

Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors

scientific article published on 01 February 2019

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

scientific article

Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state

scientific article published on 01 April 2019

Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure

scientific article published on 05 October 2020

Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer

scientific article published on 27 March 2019

Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.

scientific article published on 8 February 2017

Systematic analysis of telomere length and somatic alterations in 31 cancer types.

scientific article published on 30 January 2017

The somatic genomic landscape of chromophobe renal cell carcinoma

scientific article (publication date: 8 September 2014)

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