List of works - Matthew L Edin

Basal and inducible anti-inflammatory epoxygenase activity in endothelial cells.

scientific article published on 13 March 2014

CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice

scientific article

CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure.

scientific article published on 21 October 2013

CYP450-derived oxylipins mediate inflammatory resolution.

scientific article published on 25 May 2016

Characterization of the Cytochrome P450 epoxyeicosanoid pathway in non-alcoholic steatohepatitis

scientific article published on 8 July 2016

Commercial scale production of RvD4 opens the resolving door to new research

scientific article published on 30 March 2018

Contribution of alveolar type II cell-derived cyclooxygenase-2 to basal airway function, lung inflammation, and lung fibrosis

scientific article

Cyclooxygenase-2 regulates Th17 cell differentiation during allergic lung inflammation

scientific article

Cytochrome P450 2C8 ω3-long-chain polyunsaturated fatty acid metabolites increase mouse retinal pathologic neovascularization--brief report

scientific article published on 23 January 2014

Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization

scientific article published on 21 August 2017

Cytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patients

scientific article

Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice.

scientific article published on 16 August 2012

Effect of ciprofloxacin on the proliferation of osteoblast‐like MG‐63 human osteosarcoma cells in vitro ⬇️

scientific article published on July 1, 1998

Endogenous epoxygenases are modulators of monocyte/macrophage activity

scientific article

Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice

scientific article

Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart

scientific article

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.

scientific article

Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia

scientific article published on 3 January 2018

Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function

scientific article published on 17 December 2020

Epoxyeicosanoids promote organ and tissue regeneration.

scientific article published on 29 July 2013

Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity

scientific article

Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice

scientific article

Inducible CYP2J2 and its product 11,12-EET promotes bacterial phagocytosis: a role for CYP2J2 deficiency in the pathogenesis of Crohn's disease?

scientific article

Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation.

scientific article

Inhibition of PKA blocks fibroblast migration in response to growth factors.

scientific article published on November 2001

Integrin regulation of cell signalling and motility.

scientific article published on June 2004

Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins

scientific article

Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A2 Proves Renal Origins of Urinary PGI-M and TX-M.

scientific article published on 3 January 2018

Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation

scientific article published on 23 April 2016

Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy

scientific article

Oviductal estrogen receptor α signaling prevents protease-mediated embryo death

scientific article

Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2j Subfamily: Tissue Distribution and Regulation

scientific article published on 20 May 2015

Raf-1 serine 338 phosphorylation plays a key role in adhesion-dependent activation of extracellular signal-regulated kinase by epidermal growth factor.

scientific article

Regulation of T helper cell subsets by cyclooxygenases and their metabolites

scientific article

Role of cyclooxygenase-2 in exacerbation of allergen-induced airway remodeling by multiwalled carbon nanotubes.

scientific article published on October 2013

Role of endothelial soluble epoxide hydrolase in cerebrovascular function and ischemic injury.

scientific article

Roles of the epoxygenase CYP2J2 in the endothelium.

scientific article published on 06 March 2013

Rosuvastatin attenuates the elevation in blood pressure induced by overexpression of human C-reactive protein.

scientific article

Sinus Surgery Is Associated with a Decrease in Aspirin-Induced Reaction Severity in Patients with Aspirin Exacerbated Respiratory Disease

scientific article published on 21 December 2018

The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease.

scientific article

Tissue kallikrein reverses insulin resistance and attenuates nephropathy in diabetic rats by activation of phosphatidylinositol 3-kinase/protein kinase B and adenosine 5'-monophosphate-activated protein kinase signaling pathways

scientific article

Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids

scientific article published on 29 April 2020

Vascular actions of 20-HETE

scientific article

Vascular characterization of mice with endothelial expression of cytochrome P450 4F2.

scientific article

List of works by Matthew L Edin

Basal and inducible anti-inflammatory epoxygenase activity in endothelial cells.

CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice

CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure.

CYP450-derived oxylipins mediate inflammatory resolution.

Characterization of the Cytochrome P450 epoxyeicosanoid pathway in non-alcoholic steatohepatitis

Commercial scale production of RvD4 opens the resolving door to new research

Contribution of alveolar type II cell-derived cyclooxygenase-2 to basal airway function, lung inflammation, and lung fibrosis

Cyclooxygenase-2 regulates Th17 cell differentiation during allergic lung inflammation

Cytochrome P450 2C8 ω3-long-chain polyunsaturated fatty acid metabolites increase mouse retinal pathologic neovascularization--brief report

Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization

Cytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patients

Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice.

Effect of ciprofloxacin on the proliferation of osteoblast‐like MG‐63 human osteosarcoma cells in vitro ⬇️

Endogenous epoxygenases are modulators of monocyte/macrophage activity

Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice

Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.

Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia

Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function

Epoxyeicosanoids promote organ and tissue regeneration.

Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity

Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice

Inducible CYP2J2 and its product 11,12-EET promotes bacterial phagocytosis: a role for CYP2J2 deficiency in the pathogenesis of Crohn's disease?

Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation.

Inhibition of PKA blocks fibroblast migration in response to growth factors.

Integrin regulation of cell signalling and motility.

Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins

Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A2 Proves Renal Origins of Urinary PGI-M and TX-M.

Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation

Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy

Oviductal estrogen receptor α signaling prevents protease-mediated embryo death

Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2j Subfamily: Tissue Distribution and Regulation

Raf-1 serine 338 phosphorylation plays a key role in adhesion-dependent activation of extracellular signal-regulated kinase by epidermal growth factor.

Regulation of T helper cell subsets by cyclooxygenases and their metabolites

Role of cyclooxygenase-2 in exacerbation of allergen-induced airway remodeling by multiwalled carbon nanotubes.

Role of endothelial soluble epoxide hydrolase in cerebrovascular function and ischemic injury.

Roles of the epoxygenase CYP2J2 in the endothelium.

Rosuvastatin attenuates the elevation in blood pressure induced by overexpression of human C-reactive protein.

Sinus Surgery Is Associated with a Decrease in Aspirin-Induced Reaction Severity in Patients with Aspirin Exacerbated Respiratory Disease

The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease.

Tissue kallikrein reverses insulin resistance and attenuates nephropathy in diabetic rats by activation of phosphatidylinositol 3-kinase/protein kinase B and adenosine 5'-monophosphate-activated protein kinase signaling pathways

Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids

Vascular actions of 20-HETE

Vascular characterization of mice with endothelial expression of cytochrome P450 4F2.