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List of works by Pascale Varlet

A case report of pseudoprogression followed by complete remission after proton-beam irradiation for a low-grade glioma in a teenager: the value of dynamic contrast-enhanced MRI.

scientific article

A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma

scientific article published on 28 December 2016

ATRT-10. SPATIO-TEMPORAL DELETION OF SMARCB1 DETERMINES MOUSE AT/RT SUBTYPES.

scientific article published on 22 June 2018

Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling

scientific article published on 01 September 2018

An Unusual Case of Constitutional Mismatch Repair Deficiency Syndrome With Anaplastic Ganglioglioma, Colonic Adenocarcinoma, Osteosarcoma, Acute Myeloid Leukemia, and Signs of Neurofibromatosis Type 1: Case Report.

scientific article published on July 2015

Arterial Spin Labeling MRI: a step forward in non-invasive delineation of focal cortical dysplasia in children

scientific article published on 13 October 2014

Arterial Spin Labeling to Predict Brain Tumor Grading in Children: Correlations between Histopathologic Vascular Density and Perfusion MR Imaging

scientific article

Astrocytes reverted to a neural progenitor-like state with transforming growth factor alpha are sensitized to cancerous transformation.

scientific article published on October 2009

Atypical teratoid rhabdoid tumor mimicking beta-catenin-positive nodular medulloblastoma ⬇️

scientific article published on January 13, 2011

Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics

scientific article published in May 2009

CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors

scientific article

CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity

scientific article

CSIG-15. PROTEOMIC AND PHOSPHOPROTEOMIC ANALYSIS OF HUMAN MEDULLOBLASTOMA REVEALS DISTINCT ACTIVATED PATHWAYS BETWEEN SUBGROUPS

CT and Multimodal MR Imaging Features of Embryonal Tumors with Multilayered Rosettes in Children

scientific article published on 07 March 2019

Candidate genes on chromosome 9q33-34 involved in the progression of childhood ependymomas.

scientific article

Childhood gangliogliomas with ependymal differentiation.

scientific article

Choroid Plexus Neoplasms: Toward a Distinction between Carcinoma and Papilloma Using Arterial Spin-Labeling.

scientific article

Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1

scientific article published on 14 December 2020

Clinical relevance of tumor cells with stem-like properties in pediatric brain tumors.

scientific article

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

scientific article

Clinicopathologic prognostic factors in childhood atypical teratoid and rhabdoid tumor of the central nervous system ⬇️

scientific article published on December 16, 2011

Co-occurrence of histone H3 K27M and BRAF V600E mutations in paediatric midline grade I ganglioglioma.

scientific article published on 16 December 2016

Combining intraoperative carmustine wafers and Stupp regimen in multimodal first-line treatment of primary glioblastomas

scientific article published on 27 February 2015

Copy number gain of 1q25 predicts poor progression-free survival for pediatric intracranial ependymomas and enables patient risk stratification: a prospective European clinical trial cohort analysis on behalf of the Children's Cancer Leukaemia Group

scientific article published on 14 February 2012

Cortical GABAergic excitation contributes to epileptic activities around human glioma.

scientific article published on July 2014

DNA methylation-based classification of central nervous system tumours

scientific article published on 14 March 2018

Deep intronic hotspot variant explaining rhabdoid tumor predisposition syndrome in two patients with atypical teratoid and rhabdoid tumor

scientific article published on 19 July 2017

Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease

scientific article published on 21 January 2017

Diagnostics of Paediatric Supratentorial RELA Ependymomas: Integration of information from Histopathology, Genetics, DNA Methylation and Imaging

article

Differential proteomic analysis of human glioblastoma and neural stem cells reveals HDGF as a novel angiogenic secreted factor.

scientific article

Dynamic imaging response following radiation therapy predicts long-term outcomes for diffuse low-grade gliomas

scientific article published on 13 March 2012

Dysembryoplastic neuroepithelial tumors: nonspecific histological forms -- a study of 40 cases.

scientific article

EPN-12PEDIATRIC SUPRATENTORIAL EPENDYMOMA: COMPARISON BETWEEN IMMUNOHISTOCHEMISTRY, FISH AND DNA METHYLATION ANALYSIS FOR RELA REARRANGEMENT AND HISTOLOGICAL CORRELATION.

scientific article published on 30 May 2016

Embryonic signature distinguishes pediatric and adult rhabdoid tumors from other SMARCB1-deficient cancers

scientific article

Epileptic seizures in anaplastic gangliogliomas.

scientific article published on 23 August 2016

Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma

scientific article published on 14 October 2019

HGG-24. MOLECULAR, PATHOLOGICAL, RADIOLOGICAL AND IMMUNE PROFILING OF NON-BRAINSTEM PAEDIATRIC HIGH GRADE GLIOMA FROM THE HERBY PHASE II RANDOMISED TRIAL

scientific article published on 22 June 2018

High frequency of germline SUFU mutations in children with desmoplastic/nodular medulloblastoma younger than 3 years of age.

scientific article

Highly vascular solitary plasmacytoma of the calvarium

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes

scientific article

Histopathologic and ultrastructural features and claudin expression in papillary tumors of the pineal region: a multicenter analysis

scientific article published on 01 June 2012

Imaging growth and isocitrate dehydrogenase 1 mutation are independent predictors for diffuse low-grade gliomas

scientific article

Imaging of gliomas at 1.5 and 3 Tesla - A comparative study

scientific article published on 18 December 2014

Imaging of non-tumorous and tumorous human brain tissues with full-field optical coherence tomography

scientific article

Improving the time-machine: estimating date of birth of grade II gliomas.

scientific article published on 14 December 2011

Incomplete penetrance of the predisposition to medulloblastoma associated with germ-line SUFU mutations

scientific article published on 14 October 2009

Innovative Therapies for Children with Cancer pediatric phase I study of erlotinib in brainstem glioma and relapsing/refractory brain tumors

scientific article

Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification

scientific article

Intracerebral small round cell tumor: An unusual case with EWS-WT1 translocation

scientific article published on 01 October 2008

Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course

scientific article published on 28 September 2019

K27M mutation in H3F3A in ganglioglioma grade I with spontaneous malignant transformation extends the histopathological spectrum of the histone H3 oncogenic pathway

scientific article published in April 2017

LG-02MYB-QKI REARRANGEMENTS IN ANGIOCENTRIC GLIOMA DRIVE TUMORIGENICITY THROUGH A TRIPARTITE MECHANISM.

scientific article published on 30 May 2016

Letter to the Editor. Expression of tissue (pro)renin receptor and concentrations of its soluble form in CSF in adult diffuse gliomas

scientific article published on 21 July 2017

Loss of SMARCE1 expression is a specific diagnostic marker of clear cell meningioma: a comprehensive immunophenotypical and molecular analysis

scientific article

MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism

scientific article

Meningeal SWI/SNF related, matrix-associated, actin-dependent regulator of chromatin, subfamily B member 1 (SMARCB1)-deficient tumours: an emerging group of meningeal tumours

scientific article published on 12 October 2016

Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas

scientific article

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups

scientific article published on 28 January 2016

Modulated release of IdUrd from poly (D,L-lactide-co-glycolide) microspheres by addition of poly (D,L-lactide) oligomers.

scientific article published in April 1999

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial.

scientific article published in May 2018

Multimodal Magnetic Resonance Imaging of Treatment-Induced Changes to Diffuse Infiltrating Pontine Gliomas in Children and Correlation to Patient Progression-Free Survival.

scientific article published on 11 April 2017

Multimodal optical analysis discriminates freshly extracted human sample of gliomas, metastases and meningiomas from their appropriate controls ⬇️

scientific article published on 02 February 2017

Multimodal optical analysis of meningioma and comparison with histopathology

scientific article

NG2+/Olig2+ cells are the major cycle-related cell population of the adult human normal brain

scientific article

Natural course and prognosis of anaplastic gangliogliomas: a multicenter retrospective study of 43 cases from the French Brain Tumor Database.

scientific article published on May 2017

Neuronal differentiation distinguishes supratentorial and infratentorial childhood ependymomas

scientific article

Neuronal immunoexpression and a distinct subtype of adult primary supratentorial glioblastoma with a better prognosis.

scientific article published on 22 June 2012

Neuropathological and neuroradiological spectrum of pediatric malignant gliomas: correlation with outcome.

scientific article

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

scientific article

Oedema-based model for diffuse low-grade gliomas: application to clinical cases under radiotherapy

scientific article

Oligodendrogliomas. Part I: Patterns of growth, histological diagnosis, clinical and imaging correlations: a study of 153 cases.

scientific article published in August 1997

Oligodendrogliomas. Part II: A new grading system based on morphological and imaging criteria

scientific article published on August 1, 1997

Outcome and prognostic factors in cerebellar glioblastoma multiforme in adults: a retrospective study from the Rare Cancer Network.

scientific article published on 11 July 2006

Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA

scientific article published on 13 February 2019

Pediatric infratentorial ganglioglioma.

scientific article published on 09 September 2015

Pineocytoma and pineal parenchymal tumors of intermediate differentiation presenting cytologic pleomorphism: a multicenter study

scientific article published on 26 March 2008

Portrait of ependymoma recurrence in children: biomarkers of tumor progression identified by dual-color microarray-based gene expression analysis

scientific article

Primary intracranial melanocytic tumor simulating pituitary macroadenoma: case report and review of the literature.

scientific article

Proteomic analysis of oligodendrogliomas expressing a mutant isocitrate dehydrogenase-1.

scientific article published on 22 September 2011

Quantitative characterization of the imaging limits of diffuse low-grade oligodendrogliomas.

scientific article published on 14 June 2013

Radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma

scientific article

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

scientific article published on 05 August 2021

Solitary fibrous tumors and hemangiopericytomas of the meninges: overlapping pathological features and common prognostic factors suggest the same spectrum of tumors

scientific article

Spectral and fluorescence lifetime endoscopic system using a double-clad photonic crystal fiber.

scientific article published in November 2016

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

scientific article

Suprasellar paraganglioma: a case report and review of the literature.

scientific article

Supratentorial hemangioblastoma in the neonatal period

scientific article published on 25 March 2009

Surgery for dysembryoplastic neuroepithelial tumors and gangliogliomas in eloquent areas. Functional results and seizure control.

scientific article published on 12 May 2017

The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway

scientific article

The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation

scientific article published on 28 January 2016

Three-tesla functional MR language mapping: comparison with direct cortical stimulation in gliomas

scientific article published on February 2015

Tolerance to Dose Escalation in Minibeam Radiation Therapy Applied to Normal Rat Brain: Long-Term Clinical, Radiological and Histopathological Analysis

scientific article published on 18 August 2015

Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas.

scientific article

[Intraparenchymal hemorrhage disclosing a primary angiitis of the central nervous system]

scientific article published on 17 March 2009

[Nontumoral epileptogenic lesions]

scientific article published on 28 April 2008

[Radiation-induced DNA fragmentation evaluated by anti-poly(ADP-ribose)immunolabeling in CHO cells. Standardization with pulsed-field electrophoresis]

scientific article published on 01 April 1998

[Thoracic aortic dissection revealed by systemic cholesterol embolism]

scientific article published on 01 October 2006

Épilepsie et lésions focales chez l’enfant. Traitement chirurgical

scientific article published on 25 April 2008

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