Search filters

List of works by Markus Mitterhauser

**-Postprandial pancreatic [11C]methionine uptake after pancreaticoduodenectomy mirrors basal beta cell function and insulin release

scientific article published on 7 July 2016

11C-methionine PET/CT imaging of 99mTc-MIBI-SPECT/CT-negative patients with primary hyperparathyroidism and previous neck surgery

scientific article

18F fluoroethylations: different strategies for the rapid translation of 11C-methylated radiotracers.

scientific article published on 21 September 2007

A new method measuring the interaction of radiotracers with the human P-glycoprotein (P-gp) transporter

scientific article published on 14 February 2018

A one-step microwave-assisted synthetic method for an O/S-chemoselective route to derivatives of the first adenosine A3 PET radiotracer

scientific article published on 02 April 2014

Aggression is related to frontal serotonin-1A receptor distribution as revealed by PET in healthy subjects

scientific article

Altered interregional molecular associations of the serotonin transporter in attention deficit/hyperactivity disorder assessed with PET.

scientific article published on 22 October 2016

Application of image-derived and venous input functions in major depression using [carbonyl-(11)C]WAY-100635.

scientific article published on 30 January 2013

Assessment of Ketamine Binding of the Serotonin Transporter in Humans with Positron Emission Tomography

scientific article published on 16 October 2017

Association Between Osteogenesis and Inflammation During the Progression of Calcified Plaque Evaluated by 18F-Fluoride and 18F-FDG.

scientific article published on 23 February 2017

Association of Protein Distribution and Gene Expression Revealed by PET and Post-Mortem Quantification in the Serotonergic System of the Human Brain

scientific article published on 30 November 2016

Attenuated serotonin transporter association between dorsal raphe and ventral striatum in major depression.

scientific article published on 17 January 2014

Binding Affinity of Some Endogenous and Synthetic TSPO Ligands Regarding the rs6971 Polymorphism

scientific article published on 29 January 2019

Binding studies of [18F]-fluoride and polyphosphonates radiolabelled with [111In], [99mTc], [153Sm], and [188Re] on bone compartments: a new model for the pre vivo evaluation of bone seekers?

scientific article published on 01 May 2004

Binding studies of [18F]-fluoride and polyphosphonates radiolabelled with [99mTc], [111In], [153Sm] and [188Re] on bone compartments: verification of the pre vivo model?

scientific article published in September 2005

Biological evaluation of 2'-[18F]fluoroflumazenil ([18F]FFMZ), a potential GABA receptor ligand for PET.

scientific article published in February 2004

Central serotonin 1A receptor binding in temporal lobe epilepsy: a [carbonyl-(11)C]WAY-100635 PET study.

scientific article published on 17 September 2010

Cerebral serotonin transporter asymmetry in females, males and male-to-female transsexuals measured by PET in vivo

scientific article published on 9 December 2012

Changes in Tumor Biology During Chemoradiation of Cervix Cancer Assessed by Multiparametric MRI and Hypoxia PET.

scientific article

Clinical outcome of standardized 177Lu-PSMA-617 therapy in metastatic prostate cancer patients receiving 7400 MBq every 4 weeks

scientific article published on 28 November 2019

Combining image-derived and venous input functions enables quantification of serotonin-1A receptors with [carbonyl-11C]WAY-100635 independent of arterial sampling

scientific article published on 2 May 2012

Comparative autoradiographic in vitro investigation of melanin concentrating hormone receptor 1 ligands in the central nervous system

scientific article published on 26 April 2014

Comparison of three different purification methods for the routine preparation of [11C] Metomidate.

scientific article published in August 2003

Cortisol plasma levels in social anxiety disorder patients correlate with serotonin-1A receptor binding in limbic brain regions

scientific article published on 2 June 2010

Detection of Bone Metastases Using 11C-Acetate PET in Patients with Prostate Cancer with Biochemical Recurrence.

scientific article published in December 2015

Development and automation of a novel NET-PET tracer: [11C]Me@APPI.

scientific article published on 21 December 2012

Development of a Novel Nonpeptidic (18)F-Labeled Radiotracer for in Vivo Imaging of Oxytocin Receptors with Positron Emission Tomography.

scientific article published on 21 January 2016

Development of a radiolabeled caninized anti-EGFR antibody for comparative oncology trials.

scientific article published on 15 September 2017

Development of potential selective and reversible pyrazoline based MAO-B inhibitors as MAO-B PET tracer precursors and reference substances for the early detection of Alzheimer's disease.

scientific article

Differential modulation of the default mode network via serotonin-1A receptors

scientific article published on 30 January 2012

EANM guideline for radionuclide therapy with radium-223 of metastatic castration-resistant prostate cancer.

scientific article published on 12 December 2017

Effects of Selective Serotonin Reuptake Inhibitors on Interregional Relation of Serotonin Transporter Availability in Major Depression.

scientific article published on 06 February 2017

Effects of Silexan on the serotonin-1A receptor and microstructure of the human brain: a randomized, placebo-controlled, double-blind, cross-over study with molecular and structural neuroimaging

scientific article

Effects of hormone replacement therapy on cerebral serotonin-1A receptor binding in postmenopausal women examined with [carbonyl-¹¹C]WAY-100635.

scientific article published on 20 March 2014

Effects of norepinephrine transporter gene variants on NET binding in ADHD and healthy controls investigated by PET

scientific article published on 17 December 2015

Erratum to: Quantitative assessment of atherosclerotic plaques on (18)F-FDG PET/MRI: comparison with a PET/CT hybrid system

scientific article published on 22 March 2016

Escitalopram enhances the association of serotonin-1A autoreceptors to heteroreceptors in anxiety disorders.

scientific article published on October 2010

Evaluation of fatty acid synthase in prostate cancer recurrence: SUV of [(11) C]acetate PET as a prognostic marker.

scientific article

Evaluation of novel tropane analogues.

scientific article published in July 2007

Expanding LogP: Present possibilities

scientific article published on 28 November 2017

Exploring the impact of BDNF Val66Met genotype on serotonin transporter and serotonin-1A receptor binding

scientific article

Gadoxetate-enhanced versus diffusion-weighted MRI for fused Ga-68-DOTANOC PET/MRI in patients with neuroendocrine tumours of the upper abdomen

scientific article

Glioma survival prediction with the combined analysis of in vivo 11C-MET-PET, ex vivo and patient features by supervised machine learning.

scientific article published on 24 November 2017

Global decrease of serotonin-1A receptor binding after electroconvulsive therapy in major depression measured by PET.

scientific article

Hide and seek: a comparative autoradiographic in vitro investigation of the adenosine A3 receptor

scientific article

High-Dose Testosterone Treatment Increases Serotonin Transporter Binding in Transgender People.

scientific article

Hypothalamic serotonin-1A receptor binding measured by PET predicts the plasma level of dehydroepiandrosterone sulfate in healthy women

scientific article

Imaging biomarkers or biomarker imaging?

scientific article

Imaging of adrenocortical metastases with [11C]metomidate.

scientific article published on 24 May 2006

Impact of COMT genotype on serotonin-1A receptor binding investigated with PET.

scientific article

Impact of electroconvulsive therapy on 5-HT1A receptor binding in major depression.

scientific article published in January 2013

Impact of hybrid PET/MR technology on multiparametric imaging and treatment response assessment of cervix cancer

scientific article published on 15 November 2017

In vitro and in vivo evaluation of [18F]ciprofloxacin for the imaging of bacterial infections with PET.

scientific article published on 4 September 2004

In vivo P-glycoprotein function before and after epilepsy surgery.

scientific article

In vivo and in vitro evaluation of [18F]FETO with respect to the adrenocortical and GABAergic system in rats.

scientific article published on 3 July 2003

In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [11C]SNAP-7941 and [18F]FE@SNAP reveal specific uptake in the ventricular system.

scientific article published on 14 August 2017

In vivo magnetic resonance imaging of pancreatic tumors using iron oxide nanoworms targeted with PTR86 peptide.

scientific article published on 06 July 2017

Influence of escitalopram treatment on 5-HT 1A receptor binding in limbic regions in patients with anxiety disorders

scientific article published on 25 March 2008

Interaction between 5-HTTLPR and 5-HT1B genotype status enhances cerebral 5-HT1A receptor binding

scientific article published on 31 January 2015

Interaction of 11C-tariquidar and 11C-elacridar with P-glycoprotein and breast cancer resistance protein at the human blood-brain barrier

scientific article published on 5 July 2013

Labelling of EDTMP (Multibone) with [111In], [99mTc] and [188Re] using different carriers for "cross complexation".

scientific article published in May 2004

Lateralization of the serotonin-1A receptor distribution in language areas revealed by PET.

scientific article

Light-dependent alteration of serotonin-1A receptor binding in cortical and subcortical limbic regions in the human brain.

scientific article published on 23 November 2011

LogP, a yesterday's value?

scientific article published on 21 March 2017

Metabolic and pharmacokinetic considerations in the design of 2-phenyl substituted metyrapone derivatives: 2-methoxyphenylmetyrapone as a radioligand for functional diagnosis of adrenal pathology

scientific article published on 01 November 1995

Metabolism and autoradiographic evaluation of [(18)F]FE@CIT: a Comparison with [(123)I]beta-CIT and [(123)I]FP-CIT.

scientific article published in May 2008

Microfluidic 68Ga-labeling: a proof of principle study.

scientific article published on 17 April 2018

Microfluidic preparation of [18F]FE@SUPPY and [18F]FE@SUPPY:2 — comparison with conventional radiosyntheses

scientific article published on 03 December 2010

Multimodal imaging of human early visual cortex by combining functional and molecular measurements with fMRI and PET.

scientific article

Multiparametric [11C]Acetate positron emission tomography-magnetic resonance imaging in the assessment and staging of prostate cancer

scientific article

Multiparametric [18F]Fluorodeoxyglucose/ [18F]Fluoromisonidazole Positron Emission Tomography/ Magnetic Resonance Imaging of Locally Advanced Cervical Cancer for the Non-Invasive Detection of Tumor Heterogeneity: A Pilot Study

scientific article

NCA nucleophilic radiofluorination on substituted benzaldehydes for the preparation of [18F]fluorinated aromatic amino acids

scientific article published on 23 November 2005

Nebivolol treatment increases splanchnic blood flow and portal pressure in cirrhotic rats via modulation of nitric oxide signalling

scientific article published on 20 January 2013

New approaches for the reliable in vitro assessment of binding affinity based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics

scientific article

New aspects on the preparation of [11C]acetate--a simple and fast approach via distillation.

scientific article published in December 2004

Normative database of the serotonergic system in healthy subjects using multi-tracer PET.

scientific article published on 10 July 2012

Optimization of [11C]DASB-synthesis: Vessel-based and flow-through microreactor methods

scientific article published on 09 August 2012

Optimization of the Automated Synthesis of [11C]mHED—Administered and Apparent Molar Activities

scientific article published on 14 January 2019

Optimization of the radiosynthesis of the Alzheimer tracer 2-(4-N-[11C]methylaminophenyl)-6-hydroxybenzothiazole ([11C]PIB).

scientific article published on 29 April 2011

PSMA Ligand PET/MRI for Primary Prostate Cancer: Staging Performance and Clinical Impact

scientific article published on 23 August 2018

Parameter evaluation and fully-automated radiosynthesis of [(11)C]harmine for imaging of MAO-A for clinical trials.

scientific article published on 7 January 2015

Pgp-mediated interaction between (R)-[11C]verapamil and tariquidar at the human blood-brain barrier: a comparison with rat data

scientific article

Pharmacokinetics of 2-methoxyphenylmetyrapone and 2-bromophenylmetyrapone in rats

scientific article published on 01 January 1999

Pioglitazone decreases portosystemic shunting by modulating inflammation and angiogenesis in cirrhotic and non-cirrhotic portal hypertensive rats

scientific article published on 13 February 2014

Positron emission tomography imaging of adrenal masses: (18)F-fluorodeoxyglucose and the 11beta-hydroxylase tracer (11)C-metomidate.

scientific article

Pre vivo, ex vivo and in vivo evaluations of [68Ga]-EDTMP.

scientific article published on May 2007

Preclinical In Vitro and In Vivo Evaluation of [18F]FE@SUPPY for Cancer PET Imaging: Limitations of a Xenograft Model for Colorectal Cancer.

scientific article published on 13 February 2018

Preclinical in vitro &in vivo evaluation of [(11)C]SNAP-7941 - the first PET tracer for the melanin concentrating hormone receptor 1.

scientific article published on 3 July 2013

Prediction of SSRI treatment response in major depression based on serotonin transporter interplay between median raphe nucleus and projection areas

scientific article published on 22 July 2012

Prediction of response and survival after standardized treatment with 7400 MBq 177Lu-PSMA-617 every 4 weeks in patients with metastatic castration-resistant prostate cancer

scientific article published on 30 October 2020

Preparation and First Preclinical Evaluation of [(18)F]FE@SNAP: A Potential PET Tracer for the Melanin-Concentrating Hormone Receptor-1 (MCHR1)

scientific article published on July 2013

Preparation and first evaluation of [(18)F]FE@SUPPY: a new PET tracer for the adenosine A(3) receptor.

scientific article published in January 2008

Preparation and pre-vivo evaluation of no-carrier-added, carrier-added and cross-complexed [68Ga]-EDTMP formulations

scientific article published on 07 June 2007

Probing the association between serotonin-1A autoreceptor binding and amygdala reactivity in healthy volunteers

scientific article published on 29 December 2017

Progesterone level predicts serotonin-1a receptor binding in the male human brain

scientific article

Quantification of Task-Specific Glucose Metabolism with Constant Infusion of 18F-FDG.

scientific article published on 7 July 2016

Quantification of the radio-metabolites of the serotonin-1A receptor radioligand [carbonyl-11C]WAY-100635 in human plasma: An HPLC-assay which enables measurement of two patients in parallel

scientific article published on 13 September 2012

Radiolabeling of [18F]altanserin — a microfluidic approach

scientific article published on 23 May 2012

Radiopharmaceutical considerations on bone seeker uptake: should we learn from therapeutical targets of bisphosphonates?

scientific article published on 30 March 2011

Radiosynthesis and first preclinical evaluation of the novel norepinephrine transporter pet-ligand [(11)C]ME@HAPTHI

scientific article

Radiosynthesis of [11C]SNAP-7941--the first PET-tracer for the melanin concentrating hormone receptor 1 (MCHR1).

scientific article published on 20 July 2012

Reconsider logP!

scientific article

Reduced serotonin-1A receptor binding in social anxiety disorder

scientific article

Reduced task durations in functional PET imaging with [18F]FDG approaching that of functional MRI

scientific article published on 30 June 2018

Regional differences in SERT occupancy after acute and prolonged SSRI intake investigated by brain PET.

scientific article published on 11 October 2013

Relation of progesterone and DHEAS serum levels to 5-HT1A receptor binding potential in pre- and postmenopausal women.

scientific article published on 21 April 2014

Reliable set-up for in-loop ¹¹C-carboxylations using Grignard reactions for the preparation of [carbonyl-¹¹C]WAY-100635 and [¹¹C]-(+)-PHNO.

scientific article published on 3 August 2013

Response assessment using 68Ga-PSMA ligand PET in patients undergoing 177Lu-PSMA radioligand therapy for metastatic castration-resistant prostate cancer.

scientific article published on 19 December 2018

SNAPshots of the MCHR1: a Comparison Between the PET-Tracers [18F]FE@SNAP and [11C]SNAP-7941

scientific article published on 01 April 2019

Serotonin-1A receptor binding is positively associated with gray matter volume -- a multimodal neuroimaging study combining PET and structural MRI.

scientific article published on 23 July 2012

Simple and rapid preparation of [11C]DASB with high quality and reliability for routine applications

scientific article

Simple and rapid quantification of serotonin transporter binding using [11C]DASB bolus plus constant infusion

scientific article published on 21 January 2017

Simultaneous analysis of 2-methoxyphenylmetyrapone and its seven potential metabolites by high-performance liquid chromatography

scientific article published on 01 December 1997

Some new methods for the synthesis of cardiac neurotransmission PET radiotracers.

scientific article published on November 1995

Sorafenib attenuates the portal hypertensive syndrome in partial portal vein ligated rats.

scientific article published on 4 August 2009

Spatial analysis and high resolution mapping of the human whole-brain transcriptome for integrative analysis in neuroimaging

scientific article published in August 2018

Spectral and chromatographic properties of 2-methoxyphenylmetyrapone and its potential metabolites

scientific article published on 01 January 1997

Speed matters to raise molar radioactivity: Fast HPLC shortens the quality control of C-11 PET-tracers

scientific article published on 21 November 2017

Syntheses of precursors and reference compounds of the melanin-concentrating hormone receptor 1 (MCHR1) tracers [¹¹C]SNAP-7941 and [¹⁸F]FE@SNAP for positron emission tomography.

scientific article published on 30 September 2013

Synthesis and biodistribution of [18F]FE@CIT, a new potential tracer for the dopamine transporter.

scientific article published in February 2005

Synthesis and in silico evaluation of novel compounds for PET-based investigations of the norepinephrine transporter.

scientific article published on 20 January 2015

Synthesis, radiosynthesis and first in vitro evaluation of novel PET-tracers for the dopamine transporter: [(11)C]IPCIT and [(18)F]FE@IPCIT.

scientific article published on 7 November 2013

Task-relevant brain networks identified with simultaneous PET/MR imaging of metabolism and connectivity.

scientific article published on 13 November 2017

The influence of the rs6295 gene polymorphism on serotonin-1A receptor distribution investigated with PET in patients with major depression applying machine learning

scientific article published on 13 June 2017

The labelling of Nanocoll® with [111In] for dual-isotope scanning

scientific article published on November 1, 2003

The norepinephrine transporter in attention-deficit/hyperactivity disorder investigated with positron emission tomography.

scientific article

The serotonin-1A receptor distribution in healthy men and women measured by PET and [carbonyl-11C]WAY-100635.

scientific article published on 10 June 2008

The stability of methyl-, ethyl- and fluoroethylesters against carboxylesterases in vitro: there is no difference

scientific article published on 01 September 2010

The value of [11C]-acetate PET and [18F]-FDG PET in hepatocellular carcinoma before and after treatment with transarterial chemoembolization and bevacizumab.

scientific article published on 29 May 2017

Toward the Optimization of (+)-[11C]PHNO Synthesis: Time Reduction and Process Validation

scientific article published on 30 September 2019

Uptake of bone-seekers is solely associated with mineralisation! A study with 99mTc-MDP, 153Sm-EDTMP and 18F-fluoride on osteoblasts.

scientific article published on 17 January 2006

Urinary metabolic profile in rat of 1-(2-methoxyphenyl)-2-methyl-2-(3-pyridyl)-1-propanone: a potential radioligand for functional diagnosis of adrenal pathology

scientific article published on 01 February 1996

Visual and semiquantitative 11C-methionine PET: An independent prognostic factor for survival of newly diagnosed and treatment naive gliomas.

scientific article published on 9 September 2017

What to consider in the development of new bone seekers: mechanistic and tracer-related aspects.

scientific article

[(18)F]FE@SNAP-a specific PET tracer for melanin-concentrating hormone receptor 1 imaging?

scientific article published on April 2016

[(18)F]FMeNER-D2: A systematic in vitro analysis of radio-metabolism

scientific article published on 13 May 2016

[11C]acetate PET as a tool for diagnosis of liver steatosis

scientific article published on 11 April 2018

[18F]Ciprofloxacin, a new positron emission tomography tracer for noninvasive assessment of the tissue distribution and pharmacokinetics of ciprofloxacin in humans.

scientific article published on October 2004

[18F]FE@SUPPY and [18F]FE@SUPPY:2--metabolic considerations.

scientific article published on 6 March 2010

[18F]FE@SUPPY: a suitable PET tracer for the adenosine A3 receptor? An in vivo study in rodents

scientific article

[18F]FETO: metabolic considerations

scientific article published on 11 May 2006

[18F]FMeNER-D2: reliable fully-automated synthesis for visualization of the norepinephrine transporter

scientific article published on 05 October 2013

[68Ga]Pentixafor-PET/MRI for the detection of Chemokine receptor 4 expression in atherosclerotic plaques.

scientific article published on 21 September 2017

[F]FEPPA: Improved Automated Radiosynthesis, Binding Affinity, and Preliminary in Vitro Evaluation in Colorectal Cancer

scientific article published on 21 February 2018

[¹⁸F]FE@SNAP-A new PET tracer for the melanin concentrating hormone receptor 1 (MCHR1): microfluidic and vessel-based approaches

scientific article