List of works - Kelley W Moremen

13C-sialic acid labeling of glycans on glycoproteins using ST6Gal-I.

scientific article published on 14 August 2008

A PEGylated photocleavable auxiliary mediates the sequential enzymatic glycosylation and native chemical ligation of peptides

scientific article published on 15 May 2015

A genetic model of substrate reduction therapy for mucopolysaccharidosis

scientific article

A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships

scientific article published on 30 October 2018

A practical synthesis of kifunensine analogues as inhibitors of endoplasmic reticulum alpha-mannosidase I.

scientific article

An automated platform for the enzyme-mediated assembly of complex oligosaccharides

Association mapping, transcriptomics, and transient expression identify candidate genes mediating plant-pathogen interactions in a tree

article published in the Proceedings of the National Academy of Sciences of the United States of America

Author Correction: Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase

scientific article published on 09 June 2020

B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan

scientific article

Biochemical characterization of functional domains of the chaperone Cosmc

scientific article

Characterization of a human core-specific lysosomal {alpha}1,6-mannosidase involved in N-glycan catabolism

scientific article

Characterizing human α-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases

scientific article published on 01 October 2020

Comparison of human poly-N-acetyl-lactosamine synthase structure with GT-A fold glycosyltransferases supports a modular assembly of catalytic subsites

scientific article published on 23 November 2020

Direct determination of multiple ligand interactions with the extracellular domain of the calcium-sensing receptor

scientific article

Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase

scientific article published in Scientific Reports

ERManI (Endoplasmic Reticulum Class I α-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway

scientific article

Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multi-omics integration

scientific article published on 04 May 2022

Elucidation of the molecular logic by which misfolded alpha 1-antitrypsin is preferentially selected for degradation.

scientific article

Emerging structural insights into glycosyltransferase-mediated synthesis of glycans

scientific article published on 19 August 2019

Energetics of substrate binding and catalysis by class 1 (glycosylhydrolase family 47) alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control

scientific article published on 23 May 2005

Enzymatic Basis for N-Glycan Sialylation: STRUCTURE OF RAT 2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATION

scientific article

Essential and mutually compensatory roles of {alpha}-mannosidase II and {alpha}-mannosidase IIx in N-glycan processing in vivo in mice

scientific journal article

Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II.

scientific article published on November 2011

Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses

scientific article published on 14 September 2021

Golgi alpha-mannosidase II deficiency in vertebrate systems: implications for asparagine-linked oligosaccharide processing in mammals

scientific article

Golgi localization of ERManI defines spatial separation of the mammalian glycoprotein quality control system

scientific article

Helicobacter pylori chronic infection and mucosal inflammation switches the human gastric glycosylation pathways

scientific article

Heparan sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells

scientific article

High Yield Expression of Recombinant Human Proteins with the Transient Transfection of HEK293 Cells in Suspension

scientific article published on 28 December 2015

High structural resolution hydroxyl radical protein footprinting reveals an extended Robo1-heparin binding interface

scientific article published on 9 March 2015

Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins

scientific article

Human Lysosomal and Jack Bean α-Mannosidases Are Retaining Glycosidases ⬇️

scientific article published on September 29, 1997

Human N-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite

scientific article published on 16 April 2018

IDAWG: Metabolic incorporation of stable isotope labels for quantitative glycomics of cultured cells

scientific article

Mapping the glycosyltransferase fold landscape using interpretable deep learning

scientific article published on 27 September 2021

Mechanistic insights into a Ca2+-dependent family of α-mannosidases in a human gut symbiont

scientific article

Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine

scientific article published on 25 May 2013

Mucin-type O-glycosylation is controlled by short- and long-range glycopeptide substrate recognition that varies among members of the polypeptide GalNAc transferase family.

scientific article published on 26 November 2015

Mutations in the alpha 1,2-mannosidase gene, MAN1B1, cause autosomal-recessive intellectual disability.

scientific article

N-linked glycan recognition and processing: the molecular basis of endoplasmic reticulum quality control

scientific article published on 30 August 2006

NMR characterization of immunoglobulin G Fc glycan motion on enzymatic sialylation

scientific article

Organizational diversity among distinct glycoprotein endoplasmic reticulum-associated degradation programs

scientific article

Probing the Substrate Specificity of Golgi α-Mannosidase II by Use of Synthetic Oligosaccharides and a Catalytic Nucleophile Mutant

scientific article

Probing the impact of GFP tagging on Robo1-heparin interaction

scientific article

Proteomic identification of glycosylphosphatidylinositol anchor-dependent membrane proteins elevated in breast carcinoma

scientific article

Regulation of glycan structures in animal tissues: transcript profiling of glycan-related genes

scientific article published on 14 April 2008

Regulation of glycan structures in murine embryonic stem cells: combined transcript profiling of glycan-related genes and glycan structural analysis.

scientific article

Selective Exo-Enzymatic Labeling Detects Increased Cell Surface Sialoglycoprotein Expression upon Megakaryocytic Differentiation

scientific article published on 5 January 2016

Sparse labeling of proteins: structural characterization from long range constraints

scientific article

Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy

Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.

scientific article published on 27 May 2016

Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells

scientific article published on 2 October 2012

Substrate specificities of recombinant murine Golgi 1,2-mannosidases IA and IB and comparison with endoplasmic reticulum and Golgi processing 1,2-mannosidases ⬇️

scientific article published on 01 October 1998

The C-terminal fragment of axon guidance molecule Slit3 binds heparin and neutralizes heparin's anticoagulant activity

scientific article

The X-lectins: a new family with homology to the Xenopus laevis oocyte lectin XL-35.

scientific article

The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition

scientific article

The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation

scientific article published on 20 May 2013

Transcript Analysis of Stem Cells ⬇️

scientific article published on January 1, 2010

Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies

scientific article

Transcriptional regulation of the protocadherin β cluster during Her-2 protein-induced mammary tumorigenesis results from altered N-glycan branching

scientific article

Two Arabidopsis proteins synthesize acetylated xylan in vitro

scientific article

Vertebrate protein glycosylation: diversity, synthesis and function ⬇️

scientific article published on June 22, 2012

List of works by Kelley W Moremen

13C-sialic acid labeling of glycans on glycoproteins using ST6Gal-I.

A PEGylated photocleavable auxiliary mediates the sequential enzymatic glycosylation and native chemical ligation of peptides

A genetic model of substrate reduction therapy for mucopolysaccharidosis

A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships

A practical synthesis of kifunensine analogues as inhibitors of endoplasmic reticulum alpha-mannosidase I.

An automated platform for the enzyme-mediated assembly of complex oligosaccharides

Association mapping, transcriptomics, and transient expression identify candidate genes mediating plant-pathogen interactions in a tree

Author Correction: Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase

B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan

Biochemical characterization of functional domains of the chaperone Cosmc

Characterization of a human core-specific lysosomal {alpha}1,6-mannosidase involved in N-glycan catabolism

Characterizing human α-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases

Comparison of human poly-N-acetyl-lactosamine synthase structure with GT-A fold glycosyltransferases supports a modular assembly of catalytic subsites

Direct determination of multiple ligand interactions with the extracellular domain of the calcium-sensing receptor

Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase

ERManI (Endoplasmic Reticulum Class I α-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway

Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multi-omics integration

Elucidation of the molecular logic by which misfolded alpha 1-antitrypsin is preferentially selected for degradation.

Emerging structural insights into glycosyltransferase-mediated synthesis of glycans

Energetics of substrate binding and catalysis by class 1 (glycosylhydrolase family 47) alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control

Enzymatic Basis for N-Glycan Sialylation: STRUCTURE OF RAT 2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATION

Essential and mutually compensatory roles of {alpha}-mannosidase II and {alpha}-mannosidase IIx in N-glycan processing in vivo in mice

Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II.

Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses

Golgi alpha-mannosidase II deficiency in vertebrate systems: implications for asparagine-linked oligosaccharide processing in mammals

Golgi localization of ERManI defines spatial separation of the mammalian glycoprotein quality control system

Helicobacter pylori chronic infection and mucosal inflammation switches the human gastric glycosylation pathways

Heparan sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells

High Yield Expression of Recombinant Human Proteins with the Transient Transfection of HEK293 Cells in Suspension

High structural resolution hydroxyl radical protein footprinting reveals an extended Robo1-heparin binding interface

Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins

Human Lysosomal and Jack Bean α-Mannosidases Are Retaining Glycosidases ⬇️

Human N-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite

IDAWG: Metabolic incorporation of stable isotope labels for quantitative glycomics of cultured cells

Mapping the glycosyltransferase fold landscape using interpretable deep learning

Mechanistic insights into a Ca2+-dependent family of α-mannosidases in a human gut symbiont

Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine

Mucin-type O-glycosylation is controlled by short- and long-range glycopeptide substrate recognition that varies among members of the polypeptide GalNAc transferase family.

Mutations in the alpha 1,2-mannosidase gene, MAN1B1, cause autosomal-recessive intellectual disability.

N-linked glycan recognition and processing: the molecular basis of endoplasmic reticulum quality control

NMR characterization of immunoglobulin G Fc glycan motion on enzymatic sialylation

Organizational diversity among distinct glycoprotein endoplasmic reticulum-associated degradation programs

Probing the Substrate Specificity of Golgi α-Mannosidase II by Use of Synthetic Oligosaccharides and a Catalytic Nucleophile Mutant

Probing the impact of GFP tagging on Robo1-heparin interaction

Proteomic identification of glycosylphosphatidylinositol anchor-dependent membrane proteins elevated in breast carcinoma

Regulation of glycan structures in animal tissues: transcript profiling of glycan-related genes

Regulation of glycan structures in murine embryonic stem cells: combined transcript profiling of glycan-related genes and glycan structural analysis.

Selective Exo-Enzymatic Labeling Detects Increased Cell Surface Sialoglycoprotein Expression upon Megakaryocytic Differentiation

Sparse labeling of proteins: structural characterization from long range constraints

Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy

Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.

Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells

Substrate specificities of recombinant murine Golgi 1,2-mannosidases IA and IB and comparison with endoplasmic reticulum and Golgi processing 1,2-mannosidases ⬇️

The C-terminal fragment of axon guidance molecule Slit3 binds heparin and neutralizes heparin's anticoagulant activity

The X-lectins: a new family with homology to the Xenopus laevis oocyte lectin XL-35.

The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition

The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation

Transcript Analysis of Stem Cells ⬇️

Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies

Transcriptional regulation of the protocadherin β cluster during Her-2 protein-induced mammary tumorigenesis results from altered N-glycan branching

Two Arabidopsis proteins synthesize acetylated xylan in vitro

Vertebrate protein glycosylation: diversity, synthesis and function ⬇️