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List of works by Alexander Swarbrick

A niche-dependent myeloid transcriptome signature defines dormant myeloma cells

scientific article published on 25 April 2019

A single-cell and spatially resolved atlas of human breast cancers

scientific article published on 06 September 2021

Annexin A6 is a scaffold for PKCα to promote EGFR inactivation ⬇️

scientific article published on July 16, 2012

Antiprogestin inhibition of cell cycle progression in T-47D breast cancer cells is accompanied by induction of the cyclin-dependent kinase inhibitor p21.

scientific article published on January 1997

Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancer

scientific article

Cooperation of p27(Kip1) and p18(INK4c) in progestin-mediated cell cycle arrest in T-47D breast cancer cells.

scientific article

Could the properties of IL-27 make it an ideal adjuvant for anticancer immunotherapy?

scientific article published on July 2013

Development and validation of a targeted gene sequencing panel for application to disparate cancers

scientific article published on 19 November 2019

Discovering cancer vulnerabilities using high-throughput micro-RNA screening

scientific article published on 16 November 2017

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells

scientific article (publication date: December 2015)

ELF5 modulates the estrogen receptor cistrome in breast cancer

scientific article published on 02 January 2020

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.

scientific article

Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression

scientific article published on 06 June 2014

Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models

scientific article published on 03 August 2021

Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer.

scientific article

High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

scientific article published on 16 July 2019

Hormonal regulation of the Grb14 signal modulator and its role in cell cycle progression of MCF-7 human breast cancer cells.

scientific article

ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities

scientific article published on 14 May 2014

ID4 controls luminal lineage commitment in normal mammary epithelium and inhibits BRCA1 function in basal-like breast cancer

scientific article

ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype

scientific article

Interleukin-27 signaling promotes immunity against endogenously arising murine tumors

scientific article

Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway

scientific article published on February 2013

Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells ⬇️

scientific article published on June 4, 1998

Mechanisms of cyclin-dependent kinase inactivation by progestins

scientific article

Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens.

scientific article published in June 2002

MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene

scientific article published on 13 June 2015

MicroRNA-Related DNA Repair/Cell-Cycle Genes Independently Associated With Relapse After Radiation Therapy for Early Breast Cancer

scientific article published on 3 September 2015

MicroRNAs as potential therapeutics to enhance chemosensitivity in advanced prostate cancer.

scientific article

MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells

scientific article

New insights into signalling networks regulating breast cancer stem cells.

scientific article

New insights into the role of ID proteins in breast cancer metastasis: a MET affair

scientific article

Nucleotide variation in the cytidine triphosphate synthetase gene of Giardia duodenalis

scientific article published on 01 November 1997

Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways.

scientific article

Programmed death ligand 1 expression in triple-negative breast cancer is associated with tumour-infiltrating lymphocytes and improved outcome.

scientific article published on 20 November 2015

Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer

scientific article published on 11 June 2020

Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer

scientific article

Redefining the expression and function of the inhibitor of differentiation 1 in mammary gland development

scientific article

Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer

scientific article

Stromal cell diversity associated with immune evasion in human triple-negative breast cancer

scientific article published on 13 August 2020

The Hedgehog signalling pathway as a therapeutic target in early breast cancer development.

scientific article published on September 2009

The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy ⬇️

scientific article published on March 28, 2013

The helix-loop-helix protein Id1 requires cyclin D1 to promote the proliferation of mammary epithelial cell acini.

scientific article published in April 2008

Therapeutic targets in triple negative breast cancer ⬇️

scientific article published on February 22, 2013

Tumour Stroma Ratio Assessment Using Digital Image Analysis Predicts Survival in Triple Negative and Luminal Breast Cancer

scientific article published on 13 December 2020

Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells.

scientific article published on 21 September 2010

Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growth

scientific article

c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer.

scientific article published on 23 September 2013

miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma.

scientific article

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