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List of works by Jesse Engreitz

A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression.

scientific article

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

article published in 2021

Activity-by-contact model of enhancer-promoter regulation from thousands of CRISPR perturbations

scientific article published on 29 November 2019

Activity-dependent regulome of human GABAergic neurons reveals new patterns of gene regulation and neurological disease heritability

scientific article published on 04 February 2021

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets ⬇️

journal article from 'Nature' published in 2021

CRISPR Tools for Systematic Studies of RNA Regulation

scientific article published on 01 August 2019

CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data

scientific article published on 01 December 2018

Cohesin Loss Eliminates All Loop Domains

scientific article published in October 2017

Compatibility rules of human enhancer and promoter sequences

scientific article published in July 2022

Content-based microarray search using differential expression profiles ⬇️

scientific article published on December 21, 2010

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

article published in 2017

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.

scientific article

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

scientific article published in Nature Communications

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

Discovering metabolic disease gene interactions by correlated effects on cellular morphology

article

Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

scientific article published on 24 October 2016

Erratum: Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

scientific article published in September 2017

Functional disease architectures reveal unique biological role of transposable elements

scientific article published on 06 September 2019

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis

scientific article published on 09 May 2019

Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

scientific article published on 9 August 2017

Genome-wide enhancer maps link risk variants to disease genes

scientific article published on 07 April 2021

HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes

scientific article published on 21 December 2020

Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics

scientific article

Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics

scientific article published on 29 September 2022

Independent component analysis: mining microarray data for fundamental human gene expression modules

scientific article

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

scientific article published on 14 October 2020

Local regulation of gene expression by lncRNA promoters, transcription and splicing.

scientific article published on 26 October 2016

Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression

scientific article

Neuregulin autocrine signaling promotes self-renewal of breast tumor-initiating cells by triggering HER2/HER3 activation.

scientific article published on 31 October 2013

Positional specificity of different transcription factor classes within enhancers

article published in the Proceedings of the National Academy of Sciences of the United States of America

Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features

scientific article published on 06 March 2020

ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression ⬇️

scientific article published on October 3, 2011

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

scientific article published in Nature Communications

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

scientific article published on 01 April 2020

Publisher Correction: The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

scientific article published in Nature

RNA antisense purification (RAP) for mapping RNA interactions with chromatin

scientific article published on January 2015

RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites

scientific article

Recurrent and functional regulatory mutations in breast cancer

scientific article published on 28 June 2017

Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

scientific article published on 9 March 2018

Systematic dissection of genomic features determining transcription factor binding and enhancer function

scientific article published on 30 January 2017

Systematic mapping of functional enhancer-promoter connections with CRISPR interference

scientific article

The Lin28/let-7 axis regulates glucose metabolism

scientific article

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

scientific article published in Nature

The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome

scientific article

Three-Dimensional Genome Architecture Influences Partner Selection for Chromosomal Translocations in Human Disease ⬇️

scientific article published on September 28, 2012

Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre

scientific article

Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA.

scientific article

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