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List of works by Francesco Fornai

(+)MK-801 prevents the DDC-induced enhancement of MPTP toxicity in mice

scientific article published on 01 December 1994

3-(Fur-2-yl)-10-(2-phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one, a novel adenosine receptor antagonist with A(2A)-mediated neuroprotective effects

scientific article

5-HT(2C) serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice

scientific article published on 2 July 2015

A Decrease of Brain MicroRNA-122 Level Is an Early Marker of Cerebrovascular Disease in the Stroke-Prone Spontaneously Hypertensive Rat.

scientific article

A New Splicing Mutation in the L1CAM Gene Responsible for X-Linked Hydrocephalus (HSAS).

scientific article

A Re-Appraisal of Pathogenic Mechanisms Bridging Wet and Dry Age-Related Macular Degeneration Leads to Reconsider a Role for Phytochemicals

scientific article published on 03 August 2020

A damage to locus coeruleus neurons converts sporadic seizures into self-sustaining limbic status epilepticus

scientific article

A hypothesis on prion disorders: are infectious, inherited, and sporadic causes so distinct?

scientific article

A small dose of apomorphine counteracts the deleterious effects of middle cerebral artery occlusion in different models

scientific article

Abnormal involuntary movements (AIMs) following pulsatile dopaminergic stimulation: severe deterioration and morphological correlates following the loss of locus coeruleus neurons.

scientific article published on 15 December 2006

Abnormal morphology of peripheral cell tissues from patients with Huntington disease

scientific article

Activation of brain metabolism and fos during limbic seizures: the role of locus coeruleus.

scientific article published on 6 March 2008

Alpha-synuclein and autophagy as common steps in neurodegeneration.

scientific article published on 25 June 2008

Ambiguous Effects of Autophagy Activation Following Hypoperfusion/Ischemia

scholarly article by Michela Ferrucci published in September 2018

Amphetamines induce ubiquitin-positive inclusions within striatal cells.

scientific article published in October 2003

An attempt to dissect a peripheral marker based on cell pathology in Parkinson's disease

scientific article published on 9 June 2021

Antitumor activity of [Pt(O,O'-acac)(γ-acac)(DMS)] in mouse xenograft model of breast cancer

scientific article

Antitumour and antiangiogenic activities of [Pt(O,O'-acac)(γ-acac)(DMS)] in a xenograft model of human renal cell carcinoma.

scientific article published on 28 June 2016

Arginine:glycine amidinotransferase deficiency: the third inborn error of creatine metabolism in humans

scientific article

Brain Overexpression of Uncoupling Protein-2 (UCP2) Delays Renal Damage and Stroke Occurrence in Stroke-Prone Spontaneously Hypertensive Rats

scientific article published on 16 June 2020

Brain diseases and tumorigenesis: The good and bad cops of pentraxin3.

scientific article

Brief and repeated noise exposure produces different morphological and biochemical effects in noradrenaline and adrenaline cells of adrenal medulla.

scientific article published in February 2002

CAPS1 regulates catecholamine loading of large dense-core vesicles

scientific journal article

Cell Clearing Systems Bridging Neuro-Immunity and Synaptic Plasticity ⬇️

scientific article published on 04 May 2019

Cell-Clearing Systems Bridging Repeat Expansion Proteotoxicity and Neuromuscular Junction Alterations in ALS and SBMA

scientific article published on 04 June 2020

Chronic alcohol administration causes expression of calprotectin and RAGE altering the distribution of zinc ions in mouse testis

scientific article

Compartment-dependent mitochondrial alterations in experimental ALS, the effects of mitophagy and mitochondriogenesis

scientific article

Continuous subcutaneous infusion of apomorphine rescues nigro-striatal dopaminergic terminals following MPTP injection in mice.

scientific article published in March 2002

Correlation between changes in CSF dopamine turnover and development of dyskinesia in Parkinson's disease.

scientific article published on 17 November 2008

Corticosterone Upregulates Gene and Protein Expression of Catecholamine Markers in Organotypic Brainstem Cultures

scientific article published on 14 June 2019

DNA fragmentation and oxidative stress in the hippocampal formation: a bridge between 3,4-methylenedioxymethamphetamine (ecstasy) intake and long-lasting behavioral alterations

scientific article

Dickkopf-3 Upregulates VEGF in Cultured Human Endothelial Cells by Activating Activin Receptor-Like Kinase 1 (ALK1) Pathway

scientific article published on 14 March 2017

Different sub-cellular localization of alpha-synuclein in the C57BL\6J mouse's central nervous system by two novel monoclonal antibodies

scientific article published on 21 December 2010

Dissecting Molecular Features of Gliomas: Genetic Loci and Validated Biomarkers

scientific article published on 20 January 2020

Dopamine stimulation via infusion in the lateral ventricle

scientific article published in August 2006

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

scientific article

Ecstasy during loud noise exposure induces dramatic ultrastructural changes in the heart

scientific article published in July 2002

Effects of bevacizumab on neuronal viability of retinal ganglion cells in rats.

scientific article published on 15 August 2012

Effects of loud noise exposure on DNA integrity in rat adrenal gland

scientific article

Effects of loud noise exposure on mouse myocardium: A comparison with the rat

scientific article published on 01 October 2002

Effects of methamphetamine on the cerebellar cortex: a preliminary study

scientific article published in August 2006

Effects of repeated low doses of MDMA on EEG activity and fluoro-jade B histochemistry.

scientific article published in October 2004

Effects of vitamin B12 on the corneal nerve regeneration in rats

scientific article published on 29 January 2014

Egas Moniz: 90 Years (1927-2017) from Cerebral Angiography

scientific article published on 19 September 2017

Endogenous 3-Iodothyronamine (T1AM) and Synthetic Thyronamine-like Analog SG-2 Act as Novel Pleiotropic Neuroprotective Agents Through the Modulation of SIRT6

scientific article published on 26 February 2020

Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.

scientific article published in January 2004

Enhanced tau phosphorylation in the hippocampus of mice treated with 3,4-methylenedioxymethamphetamine ("Ecstasy").

scientific article

Epigenetic Effects Induced by Methamphetamine and Methamphetamine-Dependent Oxidative Stress

scientific article published on 22 July 2018

Erratum to "Mitochondrial Serine Protease HTRA2 p.G399S in a Female with Di George Syndrome and Parkinson's Disease"

scientific article published on 09 September 2018

Fine ultrastructure and biochemistry of PC12 cells: a comparative approach to understand neurotoxicity

scientific article published on 6 December 2006

Four Copies of SNCA Responsible for Autosomal Dominant Parkinson's Disease in Two Italian Siblings.

scientific article published on 9 November 2015

Genetic or pharmacological blockade of noradrenaline synthesis enhances the neurochemical, behavioral, and neurotoxic effects of methamphetamine

scientific article

Genotype-, aging-dependent abnormal caspase activity in Huntington disease blood cells.

scientific article published on 26 April 2011

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

High number of striatal dopaminergic neurons during early postnatal development: correlation analysis with dopaminergic fibers

scientific article published on 29 August 2008

Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases.

scientific article published on 07 March 2013

Immunohistochemical evidence and ultrastructural compartmentalization of a new antioxidant enzyme in the rat substantia nigra.

scientific article

Impairment of the autophagic flux in astrocytes intoxicated by trimethyltin

scientific article

Inclusion Dynamics in PC12 is Comparable Between Amphetamines and MPTP

scientific article published on 01 August 2006

Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is required for the development of ischemic neuronal death.

scientific article published in March 2005

Induction of the Wnt inhibitor, Dickkopf-1, is associated with neurodegeneration related to temporal lobe epilepsy

scientific article published in April 2007

Intermittent Dopaminergic stimulation causes behavioral sensitization in the addicted brain and parkinsonism.

scientific article published on January 2009

Intracellular pathways underlying the effects of lithium.

scientific article published on September 2010

Involvement of dopamine receptors and beta-arrestin in metamphetamine-induced inclusions formation in PC12 cells

scientific article published on 7 February 2008

Lack of alpha 1b-adrenergic receptor protects against epileptic seizures.

scientific article published in January 2009

Lack or Inhibition of Dopaminergic Stimulation Induces a Development Increase of Striatal Tyrosine Hydroxylase-Positive Interneurons ⬇️

scientific article published on September 18, 2012

Lithium delays progression of amyotrophic lateral sclerosis

scholarly article

Lithium improves survival of PC12 pheochromocytoma cells in high-density cultures and after exposure to toxic compounds

scientific article published on 20 January 2014

Lithium in ALS: from the bench to the bedside

scientific article published on 01 April 2008

Lithium limits trimethyltin-induced cytotoxicity and proinflammatory response in microglia without affecting the concurrent autophagy impairment.

scientific article

Localization of a glutathione-dependent dehydroascorbate reductase within the central nervous system of the rat

scientific article published on 01 January 1999

Locus coeruleus and neuronal plasticity in a model of focal limbic epilepsy

scientific article

Loss of spinal motor neurons and alteration of alpha-synuclein immunostaining in MPTP induced Parkinsonism in mice.

scientific article

Loud Noise Exposure Produces DNA, Neurotransmitter and Morphological Damage within Specific Brain Areas.

scientific article published on 26 June 2017

Loud noise enhances nigrostriatal dopamine toxicity induced by MDMA in mice

scientific article published in July 2004

MDMA and seizures: a dangerous liaison?

scientific article published on August 2006

MPTP- but not methamphetamine-induced parkinsonism extends to catecholamine neurons in the gut.

scientific article

MPTP-induced Parkinsonism is associated with damage to Leydig cells and testosterone loss.

scientific article published on 8 July 2008

MPTP-induced parkinsonism extends to a subclass of TH-positive neurons in the gut.

scientific article published on 5 August 2010

Mechanisms involved in the formation of dopamine-induced intracellular bodies within striatal neurons

scientific article published on 5 February 2007

Merging the Multi-Target Effects of Phytochemicals in Neurodegeneration: From Oxidative Stress to Protein Aggregation and Inflammation

scientific article published on 20 October 2020

Methamphetamine increases Prion Protein and induces dopamine-dependent expression of protease resistant PrPsc.

scientific article published on July 2017

Methamphetamine persistently increases alpha-synuclein and suppresses gene promoter methylation within striatal neurons

scientific article published on 28 May 2019

Mitochondrial Serine Protease HTRA2 p.G399S in a Female with Di George Syndrome and Parkinson's Disease

scientific article published on 21 June 2018

Modulation of dihydroxyphenylacetaldehyde extracellular levels in vivo in the rat striatum after different kinds of pharmacological treatment

scientific article published on 01 April 2000

Morphological alterations induced by loud noise in the myocardium: the role of benzodiazepine receptors.

scientific article

Morphological effects in the mouse myocardium after methylenedioxymethamphetamine administration combined with loud noise exposure

Morphological evidence that xenon neuroprotects against N-methyl-DL-aspartic acid-induced damage in the rat arcuate nucleus: a time-dependent study

scientific article published in August 2006

Motor neuron pathology and behavioral alterations at late stages in a SMA mouse model.

scientific article published on 5 January 2012

Natale et. al.'s response to Stecco's fascial nomenclature editorial.

scientific article published on 2 July 2014

Neuronal inclusions in degenerative disorders Do they represent static features or a key to understand the dynamics of the disease?

scientific article

Neurons other than motor neurons in motor neuron disease

scientific article published on 11 April 2017

New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection

scientific article published on 12 December 2017

Noradrenaline in Parkinson's disease: from disease progression to current therapeutics.

scientific article published on January 2007

Noradrenergic Modulation of Methamphetamine‐Induced Striatal Dopamine Depletion ⬇️

scientific article published on May 30, 1998

Noradrenergic loss enhances MDMA toxicity and induces ubiquitin-positive striatal whorls.

scientific article published on September 2002

Norepinephrine loss exacerbates methamphetamine-induced striatal dopamine depletion in mice

scientific article published on 01 September 1995

Occurrence of neuronal inclusions combined with increased nigral expression of alpha-synuclein within dopaminergic neurons following treatment with amphetamine derivatives in mice

scientific article published in May 2005

Overexpression of alpha-synuclein following methamphetamine: is it good or bad?

scientific article published on August 2006

PAR1 activation affects the neurotrophic properties of Schwann cells

scientific article published on 4 January 2017

PCR-based approach for qualitative molecular analysis of six neurotropic pathogens

scientific article published on January 2017

Parallel manifestations of neuropathologies in the enteric and central nervous systems

scientific article

Parkinson's disease and the gut: a well known clinical association in need of an effective cure and explanation

scientific article published on July 2008

Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

scientific article

Pathways of methamphetamine toxicity.

scientific article

Pentraxin 3 Induces Vascular Endothelial Dysfunction Through a P-selectin/Matrix Metalloproteinase-1 Pathway

scientific article published on 6 March 2015

Phytochemicals Bridging Autophagy Induction and Alpha-Synuclein Degradation in Parkinsonism

scientific article published on 03 July 2019

Plastic changes in the spinal cord in motor neuron disease

scientific article published on 16 April 2014

Potential Antidepressant Effects of Scutellaria baicalensis, Hericium erinaceus and Rhodiola rosea

scientific article published on 12 March 2020

Presence of beta-arrestin in cellular inclusions in metamphetamine-treated PC12 cells.

scientific article published on October 2003

Previous exposure to (+/-) 3,4-methylenedioxymethamphetamine produces long-lasting alteration in limbic brain excitability measured by electroencephalogram spectrum analysis, brain metabolism and seizure susceptibility.

scientific article

Prion Protein in Glioblastoma Multiforme

scientific article published on 15 October 2019

Prion-like mechanisms in epileptogenesis.

scientific article

Promiscuous Roles of Autophagy and Proteasome in Neurodegenerative Proteinopathies

scientific article published on 24 April 2020

Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.

scientific article published on August 2003

Quantitative Ultrastructural Morphometry and Gene Expression of mTOR-Related Mitochondriogenesis within Glioblastoma Cells ⬇️

scientific article published on 27 June 2020

Rapamycin inhibits the growth of glioblastoma.

scientific article

Rapamycin promotes differentiation increasing βIII-tubulin, NeuN, and NeuroD while suppressing nestin expression in glioblastoma cells

scientific article published on 4 March 2017

Region-specific DNA alterations in focally induced seizures

scientific article published on 20 April 2014

Resistance to striatal dopamine depletion induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice expressing human mutant Cu,Zn superoxide dismutase.

scientific article published in June 2002

Reversible brain creatine deficiency in two sisters with normal blood creatine level

scientific article published on 01 April 2000

Role of autophagy inhibitors and inducers in modulating the toxicity of trimethyltin in neuronal cell cultures.

scientific article published on 14 March 2012

Selective lesion of the nigrostriatal dopaminergic pathway by MPTP and acetaldehyde or diethyldithiocarbamate

scientific article published on March 1, 1992

Severe and rapidly-progressive Lafora disease associated with NHLRC1 mutation: a case report.

scientific article published on 30 May 2017

Severe ultrastructural mitochondrial changes in lymphoblasts homozygous for Huntington disease mutation

scientific article published on 9 November 2005

Similar increases in extracellular lactic acid in the limbic system during epileptic and/or olfactory stimulation.

scientific article published in January 2000

Similarities between methamphetamine toxicity and proteasome inhibition.

scientific article published in October 2004

Species differences in the role of excitatory amino acids in experimental parkinsonism

scientific article published on July 1997

Spinal cord and parkinsonism: Neuromorphological evidences in humans and experimental studies ⬇️

scientific article published on March 22, 2011

Stereoselective inhibition of muscarinic receptor subtypes by the eight stereoisomers related to rociverine

scientific article published on 01 July 1995

Striatal MPP+ levels do not necessarily correlate with striatal dopamine levels after MPTP treatment in mice

scientific article published on 01 June 1996

Striatal dopamine metabolism in monoamine oxidase B-deficient mice: a brain dialysis study

scientific article published on 01 December 1999

Striatal increase of neurotrophic factors as a mechanism of nicotine protection in experimental parkinsonism

scientific article published on January 1997

Subcellular localization of a glutathione-dependent dehydroascorbate reductase within specific rat brain regions

scientific journal article

Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine

scientific article

Systematic Morphometry of Catecholamine Nuclei in the Brainstem.

scientific article published on 2 November 2017

TREM Receptors Connecting Bowel Inflammation to Neurodegenerative Disorders

scientific article published on 21 September 2019

The "Parkinsonian heart": from novel vistas to advanced therapeutic approaches in Parkinson's disease.

scientific article published on January 2007

The Autophagoproteasome a Novel Cell Clearing Organelle in Baseline and Stimulated Conditions.

scientific article published on 21 July 2016

The Autophagy Status of Cancer Stem Cells in Gliobastoma Multiforme: From Cancer Promotion to Therapeutic Strategies

scientific article published on 05 August 2019

The Monoamine Brainstem Reticular Formation as a Paradigm for Re-Defining Various Phenotypes of Parkinson's Disease Owing Genetic and Anatomical Specificity.

scientific article

The Neuroanatomy of the Reticular Nucleus Locus Coeruleus in Alzheimer's Disease

scientific article published on 19 September 2017

The chemical neuroanatomy of vagus nerve stimulation.

scientific article published on 16 December 2010

The connections of Locus Coeruleus with hypothalamus: potential involvement in Alzheimer's disease

scientific article published in May 2021

The emerging role of m-TOR up-regulation in brain Astrocytoma

scientific article published on 24 October 2016

The inflammatory protein Pentraxin 3 in cardiovascular disease

scientific article

The nature of catecholamine-containing neurons in the enteric nervous system in relationship with organogenesis, normal human anatomy and neurodegeneration.

scientific article published in September 2017

The neurotoxicity of amphetamines: bridging drugs of abuse and neurodegenerative disorders.

scientific article

The role of autophagy in epileptogenesis and in epilepsy-induced neuronal alterations

scientific article published on 14 September 2014

The role of locus coeruleus in the antiepileptic activity induced by vagus nerve stimulation

scientific article published on 03 May 2011

The role of nitric oxide in focally-evoked limbic seizures

scientific article published on 01 February 1997

The role of norepinephrine in epilepsy: from the bench to the bedside.

scientific article published in September 2004

Time-dependent changes in adrenal cortex ultrastructure and corticosterone levels after noise exposure in male rats.

scientific article published in July 2001

Transmission of prions within the gut and towards the central nervous system

scientific article published on July 2011

Ultrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesis

scientific article

Vacuolar Protein Sorting Genes in Parkinson's Disease: A Re-appraisal of Mutations Detection Rate and Neurobiology of Disease

scientific article

beta,beta'-Iminodipropionitrile-induced persistent dyskinetic syndrome in mice is transiently modified by MPTP.

scientific article published in March 1993

mTOR Modulates Methamphetamine-Induced Toxicity through Cell Clearing Systems

scientific article published on 29 October 2018

mTOR-Dependent Cell Proliferation in the Brain.

scientific article published on 13 November 2017

mTOR-Related Brain Dysfunctions in Neuropsychiatric Disorders

scientific article published on 30 July 2018

mTOR-Related Cell-Clearing Systems in Epileptic Seizures, an Update

scientific article published on 28 February 2020

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