List of works by Ming Chen

Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling

scientific article published on 18 September 2019

An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.

scientific article published on 15 January 2018

Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis

scientific article published on 26 November 2018

DOK2 inhibits EGFR-mutated lung adenocarcinoma

scientific article

Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism.

scientific article published on 15 January 2018

Designer monotransregulators provide a basis for a transcriptional therapy for de novo endocrine-resistant breast cancer.

scientific article

Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms

scientific article published on 8 January 2018

ERAP75 functions as a coactivator to enhance estrogen receptor alpha transactivation in prostate stromal cells

scientific journal article

Endosome and INPP4B.

scientific article published on 18 December 2015

Generation and characterization of a complete null estrogen receptor alpha mouse using Cre/LoxP technology.

scientific article

In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes

scientific article published on 16 April 2015

Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis

scientific article published on 16 August 2019

Loss of LDAH associated with prostate cancer and hearing loss

scientific article published on 01 December 2018

Loss of epithelial oestrogen receptor α inhibits oestrogen-stimulated prostate proliferation and squamous metaplasia via in vivo tissue selective knockout models

scientific article published on 9 November 2011

Pills of PTEN? In and out for tumor suppression.

scientific article published on 6 August 2013

Preclinical and Coclinical Studies in Prostate Cancer

scientific article published on 16 October 2017

RRR-alpha-vitamin E succinate potentiates the antitumor effect of calcitriol in prostate cancer without overt side effects

scientific article

Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway

scientific article published on 01 May 2019

Reduced prostate branching morphogenesis in stromal fibroblast, but not in epithelial, estrogen receptor α knockout mice

scientific article published on 21 May 2012

SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression.

scientific article published on 27 December 2018

Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis

scientific article

The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function

scientific article published on 7 February 2017

The expanded role of fatty acid metabolism in cancer: new aspects and targets

scientific article published on 01 September 2019

The functions and regulation of the PTEN tumour suppressor: new modes and prospects

scientific article published on 01 September 2018

The therapeutic and preventive effect of RRR-alpha-vitamin E succinate on prostate cancer via induction of insulin-like growth factor binding protein-3

scientific article published on 01 April 2007

Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway

scientific article published on November 2005

Vulnerabilities in mIDH2 AML confer sensitivity to APL-like targeted combination therapy

scientific article published on 25 April 2019

Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition.

scientific article