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List of works by Nikolaos G Frangogiannis

Active interstitial remodeling: an important process in the hibernating human myocardium.

scientific article published in May 2002

Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction

scientific article

Anti-inflammatory therapies in myocardial infarction: failures, hopes, and challenges

scientific article

Authors' Reply

scientific article published on 20 July 2016

Biomarkers: hopes and challenges in the path from discovery to clinical practice.

scientific article

CD44 is critically involved in infarct healing by regulating the inflammatory and fibrotic response

scientific article published on 01 February 2008

CXCR3-independent actions of the CXC chemokine CXCL10 in the infarcted myocardium and in isolated cardiac fibroblasts are mediated through proteoglycans

scientific article

Cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions

scientific article published on 01 February 1999

Cell biological mechanisms in regulation of the post-infarction inflammatory response

scientific article published on 13 December 2017

Cell therapy for peripheral artery disease.

scientific article published on 13 February 2018

Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload.

scientific article

Chemokines and cardiac fibrosis.

scientific article published on June 2009

Chemokines in ischemia and reperfusion

scientific article published on 01 May 2007

Chemokines in myocardial infarction: translating basic research into clinical medicine

scientific article published on 01 July 2008

Chemokines in myocardial ischemia.

scientific article

Contribution of extramedullary organs in myocardial inflammation and remodeling: does the spleen cause cardiac melancholy?

scientific article published on January 2014

Critical role of endogenous thrombospondin-1 in preventing expansion of healing myocardial infarcts

scientific article published on 31 May 2005

Critical role of monocyte chemoattractant protein-1/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy

scientific article published on 01 February 2007

Crossing Into the Next Frontier of Cardiac Extracellular Matrix Research

scientific article published on October 2016

Cyclophosphamide in the treatment of toxic epidermal necrolysis.

scientific article published in October 1996

Cytokines and the microcirculation in ischemia and reperfusion

scientific article published on 01 December 1998

Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities

scientific article

Editor's Choice- Activation of the innate immune system in the pathogenesis of acute heart failure

scientific article published on 28 April 2017

Editorial commentary: Myocardial fibrosis in genetic cardiomyopathies: A cause of dysfunction, or simply an epiphenomenon?

scientific article published on 05 October 2019

Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction

scientific article published on 26 May 2006

Emerging roles for macrophages in cardiac injury: cytoprotection, repair, and regeneration

scientific article

Endocarditis and Ureaplasma urealyticum osteomyelitis in a hypogammaglobulinemic patient. A case report and review of the literature.

scientific article

Endogenous IRAK-M attenuates postinfarction remodeling through effects on macrophages and fibroblasts.

scientific article

Endogenous Thrombospondin 1 Protects the Pressure-Overloaded Myocardium by Modulating Fibroblast Phenotype and Matrix Metabolism ⬇️

scientific article published on September 26, 2011

Evidence for an active inflammatory process in the hibernating human myocardium

scientific article published on April 2002

Fact and Fiction About Fibroblast to Endothelium Conversion: Semantics and Substance of Cellular Identity

scientific article published on 26 October 2020

Fibroblast-Extracellular Matrix Interactions in Tissue Fibrosis

scientific article published on 5 February 2016

Fibroblasts and the extracellular matrix in right ventricular disease.

scientific article published in October 2017

Fibroblasts in myocardial infarction: a role in inflammation and repair

scientific article published on 07 December 2013

Fibroblasts in post-infarction inflammation and cardiac repair.

scientific article published on 7 September 2012

Guidelines for Experimental Models of Myocardial Ischemia and Infarction

scientific article published on 12 January 2018

How do endosomal Toll-like receptors sense and extend ischaemic myocardial injury?

scientific article published on 01 October 2019

IL-1 induces proinflammatory leukocyte infiltration and regulates fibroblast phenotype in the infarcted myocardium.

scientific article published on 27 September 2013

IL-10 is induced in the reperfused myocardium and may modulate the reaction to injury

scientific article published on 01 September 2000

Identification of mast cells in the cellular response to myocardial infarction.

scientific article published in January 2006

Immune cells in repair of the infarcted myocardium

scientific article

Impact of myocardial structure and function postinfarction on diastolic strain measurements: implications for assessment of myocardial viability.

scientific article published on 23 September 2005

Increased myocardial susceptibility to repetitive ischemia with high-fat diet-induced obesity

scientific article

Induction and suppression of interferon-inducible protein 10 in reperfused myocardial infarcts may regulate angiogenesis

scientific article published on 01 June 2001

Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction.

scientific article published on 24 September 2009

Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges.

scientific article published on 17 July 2015

Inflammation in cardiac injury, repair and regeneration.

scientific article published on May 2015

Inflammatory Cytokines and Chemokines as Therapeutic Targets in Heart Failure

scientific article published on 09 September 2020

Inflammatory mechanisms in myocardial infarction.

scientific article published on September 2003

Integrated multimodal-catheter imaging unveils principal relationships among ventricular electrical activity, anatomy, and function

scientific article published on 14 December 2007

Interleukin-1 in cardiac injury, repair, and remodeling: pathophysiologic and translational concepts

scientific article published on January 2015

Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling.

scientific article published on 5 June 2008

Left atrial remodeling, hypertrophy, and fibrosis in mouse models of heart failure.

scientific article published on 21 June 2017

MCP-1/CCL2 as a therapeutic target in myocardial infarction and ischemic cardiomyopathy.

scientific article published on June 2007

MCSF expression is induced in healing myocardial infarcts and may regulate monocyte and endothelial cell phenotype.

scientific article published on 10 April 2003

Macrophages in the Remodeling Failing Heart

scientific article published on September 2016

Mast cell tryptase may modulate endothelial cell phenotype in healing myocardial infarcts

scientific article published on January 2005

Matricellular Proteins in Cardiac Adaptation and Disease ⬇️

scientific article published on April 1, 2012

Mechanisms of Fibroblast Activation in the Remodeling Myocardium

scientific article published on 22 April 2017

Mediators secreted by myeloid cells may protect and repair the infarcted myocardium

scientific article published on 01 June 2015

MicroRNAs and endothelial function: many challenges and early hopes for clinical applications.

scientific article

Microvascular structural correlates of myocardial contrast echocardiography in patients with coronary artery disease and left ventricular dysfunction: implications for the assessment of myocardial hibernation.

scientific article published in August 2002

Monocyte chemoattractant protein-1/CCL2 as a biomarker in acute coronary syndromes.

scientific article published on March 2009

Monocyte subsets as predictors of adverse events in patients with atherosclerosis

scientific article published on 01 September 2019

Morphological characteristics of the microvasculature in healing myocardial infarcts

scientific article published in January 2002

Myocardial Galectin-3 Expression Is Associated with Remodeling of the Pressure-Overloaded Heart and May Delay the Hypertrophic Response without Affecting Survival, Dysfunction, and Cardiac Fibrosis.

scientific article published on 3 March 2016

Myocardial extracellular matrix: an ever-changing and diverse entity.

scientific article published on February 2014

Myofibroblasts in reperfused myocardial infarcts express the embryonic form of smooth muscle myosin heavy chain (SMemb)

scientific article published on 01 October 2000

Obesity, metabolic dysfunction, and cardiac fibrosis: pathophysiological pathways, molecular mechanisms, and therapeutic opportunities

scientific article

Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction.

scientific article

Opposing Actions of Fibroblast and Cardiomyocyte Smad3 Signaling in the Infarcted Myocardium.

scientific article published on 11 December 2017

Pathophysiology of Myocardial Infarction

scientific article published on 20 September 2015

Pemphigus of the larynx and esophagus

scientific article published on 01 May 1995

Phagocytes in ischemia injury.

scientific article

Platelet-monocyte complex formation: effect of blocking PSGL-1 alone, and in combination with alphaIIbbeta3 and alphaMbeta2, in coronary stenting

scientific article published on 01 January 2003

Regulation of the inflammatory response in cardiac repair

scientific article published on January 2012

Regulatory T cells are recruited in the infarcted mouse myocardium and may modulate fibroblast phenotype and function

scientific article

Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion

scientific article published on 01 August 1998

Smad3 Signaling Promotes Fibrosis While Preserving Cardiac and Aortic Geometry in Obese Diabetic Mice

scientific article published on 18 May 2015

Stem cell factor induction is associated with mast cell accumulation after canine myocardial ischemia and reperfusion

scientific article published on 01 August 1998

Stromal cell-derived factor-1-mediated angiogenesis for peripheral arterial disease: ready for prime time?

scientific article published on 14 March 2011

TGF-β signaling in fibrosis ⬇️

scientific article published on July 11, 2011

Targeting inflammatory pathways in myocardial infarction.

scientific article published on 17 June 2013

Targeting the chemokines in cardiac repair.

scientific article published on January 2014

Targeting the chemokines in myocardial inflammation

scientific article published on 01 September 2004

Targeting the transforming growth factor (TGF)-β cascade in the remodeling heart: benefits and perils

scientific article published on 11 September 2014

The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis.

scientific article published on June 2016

The Cellular Origin of Activated Fibroblasts in the Infarcted and Remodeling Myocardium.

scientific article published in February 2018

The Functional Pluralism of Fibroblasts in the Infarcted Myocardium

scientific article published on October 2016

The Stromal Cell–Derived Factor-1/CXCR4 Axis in Cardiac Injury and Repair ⬇️

scientific article published on November 29, 2011

The cellular specificity of leptin-mediated actions in the infarcted heart.

scientific article published on 9 November 2010

The extracellular matrix in myocardial injury, repair, and remodeling.

scientific article

The immune system and cardiac repair.

scientific article published on 24 June 2008

The immune system and the remodeling infarcted heart: cell biological insights and therapeutic opportunities.

scientific article published on March 2014

The inflammatory response in myocardial injury, repair, and remodelling.

scientific article published on 25 March 2014

The mechanistic basis of infarct healing.

scientific article published on November 2006

The pathogenesis of cardiac fibrosis.

scientific article published on 07 May 2013

The prognostic value of monocyte chemoattractant protein-1/CCL2 in acute coronary syndromes

scientific article published on 13 November 2007

The reparative function of cardiomyocytes in the infarcted myocardium.

scientific article published in June 2015

The role of IL-1 in the pathogenesis of heart disease.

scientific article published on 29 May 2009

The role of Interleukin Receptor Associated Kinase (IRAK)-M in regulation of myofibroblast phenotype in vitro, and in an experimental model of non-reperfused myocardial infarction.

scientific article

The role of TGF-beta signaling in myocardial infarction and cardiac remodeling

scientific article published on 7 October 2006

The role of endogenous Smad7 in regulating macrophage phenotype following myocardial infarction

scientific article published in 2022

The role of inflammatory and fibrogenic pathways in heart failure associated with aging.

scientific article

The role of platelet-derived growth factor signaling in healing myocardial infarcts.

scientific article published on 13 November 2006

The role of the chemokines in myocardial ischemia and reperfusion

scientific article published on 01 April 2004

The role of thrombospondin (TSP)-1 in obesity and diabetes

scientific article published on 5 November 2013

The role of transforming growth factor (TGF)-β in the infarcted myocardium

scientific article

The role of α-smooth muscle actin in fibroblast-mediated matrix contraction and remodeling.

scientific article published on 4 November 2016

Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation

scientific article published on 30 September 2013

Tirofiban for cocaine-induced coronary artery thrombosis: a novel therapeutic approach.

scientific article published in November 1999

Tissue transglutaminase in the pathogenesis of heart failure

scientific article published on 13 December 2017

Tissue transglutaminase induction in the pressure-overloaded myocardium regulates matrix remodelling.

scientific article

Transforming growth factor (TGF)-β signaling in cardiac remodeling.

scientific article

Transforming growth factor-β in tissue fibrosis

scientific article published on 13 February 2020

Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.

scientific article published on 18 September 2017

Vascular mural cells in healing canine myocardial infarcts

scientific article published on 01 August 2004

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