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List of works by Tiina Kelkka

A robust pipeline with high replication rate for detection of somatic variants in the adaptive immune system as a source of common genetic variation in autoimmune disease

scientific article published on 01 April 2019

A6.02 Somatic mutations in clonally expanded CD8+T cells in patients with newly diagnosed rheumatoid arthritis

scholarly article by Tiina Kelkka et al published February 2016 in Annals of the Rheumatic Diseases

Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target.

scientific article published on 19 April 2018

Bacillus calmette-guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation

scientific article

Chronic active arthritis driven by macrophages without involvement of T cells

scientific article published on 7 March 2018

Clever-1/stabilin-1 controls cancer growth and metastasis.

scientific article published on 15 October 2014

Clonal hematopoiesis in patients with rheumatoid arthritis

scholarly article by Paula Savola et al published 26 July 2018 in Blood Cancer Journal

Enhancement of Antibody-Induced Arthritis via Toll-Like Receptor 2 Stimulation Is Regulated by Granulocyte Reactive Oxygen Species

scientific article published on 27 May 2012

Finemapping of the arthritis QTL Pia7 reveals co-localization with Oia2 and the APLEC locus

article

Hydrogen peroxide as an immunological transmitter regulating autoreactive T cells

scientific article published on 17 August 2012

Hyperinflammation of chronic granulomatous disease is abolished by NOX2 reconstitution in macrophages and dendritic cells

scientific article published on 26 July 2012

Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice

scientific article

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors

scientific article

Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice.

scientific article

NOX2 complex-derived ROS as immune regulators.

scientific article published on 11 April 2011

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

scientific article

Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature.

scientific article

Reactive oxygen species produced by the NADPH oxidase 2 complex in monocytes protect mice from bacterial infections.

scientific article published on 9 April 2012

Sex bias in MHC I-associated shaping of the adaptive immune system.

scientific article published on 12 February 2018

Somatic STAT3 mutations in the Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia

scientific article published on 7 December 2017

Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis.

scientific article

Superoxide dismutase 3 limits collagen-induced arthritis in the absence of phagocyte oxidative burst

scientific article published on 5 March 2012

The Macrophage Mannose Receptor Regulate Mannan-Induced Psoriasis, Psoriatic Arthritis, and Rheumatoid Arthritis-Like Disease Models.

scientific article published on 6 February 2018