List of works - Aina E Cohen

A capillary-based microfluidic device enables primary high-throughput room-temperature crystallographic screening

scientific article published on 14 June 2021

Acoustic Injectors for Drop-On-Demand Serial Femtosecond Crystallography.

scientific article

Allosteric control in a metalloprotein dramatically alters function ⬇️

scientific article published on December 27, 2012

An automated system to mount cryo-cooled protein crystals on a synchrotron beam line, using compact sample cassettes and a small-scale robot

scientific article (publication date: December 2002)

Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis

scientific article

Assessment of microcrystal quality by transmission electron microscopy for efficient serial femtosecond crystallography

scientific article published on March 2016

AutoDrug: fully automated macromolecular crystallography workflows for fragment-based drug discovery ⬇️

scientific article published on April 11, 2013

Beamstop with integrated X-ray sensor.

scientific article published on 25 April 2003

Blu-Ice and the Distributed Control System: software for data acquisition and instrument control at macromolecular crystallography beamlines

scientific article

Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array

scientific article

Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals

scientific article published on 26 February 2020

Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble

scientific article

Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2

scientific article

Crystal structure of the pristine peroxidase ferryl center and its relevance to proton-coupled electron transfer

scientific article published on 19 January 2016

Crystallization of Pichia pastoris lysyl oxidase

scientific article published on 23 November 2002

Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC.

scientific article

Electrostatic Fields near the Active Site of Human Aldose Reductase: 2. New Inhibitors and Complications Caused by Hydrogen Bonds

scientific article

Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking

scientific article published on 24 November 2020

Goniometer-based femtosecond X-ray diffraction of mutant 30S ribosomal subunit crystals.

scientific article published on 30 April 2015

Goniometer-based femtosecond crystallography with X-ray free electron lasers

scientific article

High-density grids for efficient data collection from multiple crystals

scientific article

How directed evolution reshapes the energy landscape in an enzyme to boost catalysis

scientific article published on 19 November 2020

Identifying, studying and making good use of macromolecular crystals.

scientific article

MAD phasing with krypton.

scientific article published in February 2001

MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone

scientific article

Mutation of the His ligand in mitoNEET stabilizes the 2Fe–2S cluster despite conformational heterogeneity in the ligand environment

scientific article

New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection

scientific article

Observation of correlated X-ray scattering at atomic resolution

scientific article

Remote access to crystallography beamlines at SSRL: novel tools for training, education and collaboration.

scientific article published on 3 August 2010

Strategies for sample delivery for femtosecond crystallography

scientific article published on 19 February 2019

Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC.

scientific article published on 26 November 2016

Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope

scientific article published on 28 March 2018

Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine

scientific article

Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine

scientific article

The 1.23 Angstrom structure of Pichia pastoris lysyl oxidase reveals a lysine-lysine cross-link

scientific article published on 19 August 2006

The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography.

scientific article

The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction

scientific article

The New Macromolecular Femtosecond Crystallography (MFX) Instrument at LCLS.

scientific article published on February 2016

The Stanford Automated Mounter: Enabling High-Throughput Protein Crystal Screening at SSRL.

scientific article published on December 2008

The Stanford Automated Mounter: pushing the limits of sample exchange at the SSRL macromolecular crystallography beamlines.

scientific article

The crystal structure of Pichia pastoris lysyl oxidase

scientific article

The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature

scientific article published on 27 May 2022

The novel 2Fe–2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain

scientific article

Transmission electron microscopy as a tool for nanocrystal characterization pre- and post-injector

scientific article

Transmission electron microscopy for the evaluation and optimization of crystal growth

scientific article

Use of transmission electron microscopy to identify nanocrystals of challenging protein targets

scientific article

Using xenon as a probe for dioxygen-binding sites in copper amine oxidases.

scientific article published in November 2004

List of works by Aina E Cohen

A capillary-based microfluidic device enables primary high-throughput room-temperature crystallographic screening

Acoustic Injectors for Drop-On-Demand Serial Femtosecond Crystallography.

Allosteric control in a metalloprotein dramatically alters function ⬇️

An automated system to mount cryo-cooled protein crystals on a synchrotron beam line, using compact sample cassettes and a small-scale robot

Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis

Assessment of microcrystal quality by transmission electron microscopy for efficient serial femtosecond crystallography

AutoDrug: fully automated macromolecular crystallography workflows for fragment-based drug discovery ⬇️

Beamstop with integrated X-ray sensor.

Blu-Ice and the Distributed Control System: software for data acquisition and instrument control at macromolecular crystallography beamlines

Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array

Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals

Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble

Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2

Crystal structure of the pristine peroxidase ferryl center and its relevance to proton-coupled electron transfer

Crystallization of Pichia pastoris lysyl oxidase

Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC.

Electrostatic Fields near the Active Site of Human Aldose Reductase: 2. New Inhibitors and Complications Caused by Hydrogen Bonds

Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking

Goniometer-based femtosecond X-ray diffraction of mutant 30S ribosomal subunit crystals.

Goniometer-based femtosecond crystallography with X-ray free electron lasers

High-density grids for efficient data collection from multiple crystals

How directed evolution reshapes the energy landscape in an enzyme to boost catalysis

Identifying, studying and making good use of macromolecular crystals.

MAD phasing with krypton.

MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone

Mutation of the His ligand in mitoNEET stabilizes the 2Fe–2S cluster despite conformational heterogeneity in the ligand environment

New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection

Observation of correlated X-ray scattering at atomic resolution

Remote access to crystallography beamlines at SSRL: novel tools for training, education and collaboration.

Strategies for sample delivery for femtosecond crystallography

Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC.

Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope

Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine

Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine

The 1.23 Angstrom structure of Pichia pastoris lysyl oxidase reveals a lysine-lysine cross-link

The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography.

The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction

The New Macromolecular Femtosecond Crystallography (MFX) Instrument at LCLS.

The Stanford Automated Mounter: Enabling High-Throughput Protein Crystal Screening at SSRL.

The Stanford Automated Mounter: pushing the limits of sample exchange at the SSRL macromolecular crystallography beamlines.

The crystal structure of Pichia pastoris lysyl oxidase

The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature

The novel 2Fe–2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain

Transmission electron microscopy as a tool for nanocrystal characterization pre- and post-injector

Transmission electron microscopy for the evaluation and optimization of crystal growth

Use of transmission electron microscopy to identify nanocrystals of challenging protein targets

Using xenon as a probe for dioxygen-binding sites in copper amine oxidases.