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List of works by Nicola Baker

An improved small-molecule inhibitor of FtsZ with superior in vitro potency, drug-like properties, and in vivo efficacy

scientific article published on 31 October 2012

Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes

scientific article

Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity

scientific article

Chemogenomic Profiling of Antileishmanial Efficacy and Resistance in the Related Kinetoplastid Parasite Trypanosoma brucei

scientific article published on 25 July 2019

Chimerization at the AQP2-AQP3 locus is the genetic basis of melarsoprol-pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates

scientific article published on 7 May 2015

Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense

scientific article published on 14 March 2016

Design, synthesis and structure-activity relationships of substituted oxazole-benzamide antibacterial inhibitors of FtsZ.

scientific article published on 13 November 2013

Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story ⬇️

scientific article published on January 30, 2013

Genetic dissection of drug resistance in trypanosomes

scientific article

Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes

scientific article published on 11 December 2014

Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6 ⬇️

scientific article published on November 18, 2010

High-throughput decoding of antitrypanosomal drug efficacy and resistance

scientific article published on 25 January 2012

Method for assessing IFN-γ responses in guinea pigs during TB vaccine trials

scientific article published on 17 August 2012

Pentamidine Is Not a Permeant but a Nanomolar Inhibitor of the Trypanosoma brucei Aquaglyceroporin-2

scientific article

Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival

scientific article published on 23 February 2021

Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs

scientific article

Vacuolar ATPase depletion affects mitochondrial ATPase function, kinetoplast dependency, and drug sensitivity in trypanosomes

scientific article published on 6 July 2015

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