Search filters

List of works by Sarina Piha-Paul

A Deep Learning Framework for Predicting Response to Therapy in Cancer

scientific article published on 01 December 2019

A Phase I Trial of Combined Ridaforolimus and MK-2206 in Patients with Advanced Malignancies

scientific article published on 17 July 2015

A decision support framework for genomically informed investigational cancer therapy

scientific article

A non-pregnant woman with elevated beta-HCG: A case of para-neoplastic syndrome in ovarian cancer

scientific article published on 21 May 2016

A phase 1 study of anti-TGFβ receptor type-II monoclonal antibody LY3022859 in patients with advanced solid tumors.

scientific article published on 09 March 2017

A phase 1 study of gemcitabine combined with dasatinib in patients with advanced solid tumors.

scientific article

A phase 1 study of intermittently administered pazopanib in combination with continuous daily dosing of lapatinib in patients with solid tumors.

scientific article

A phase I clinical trial of hepatic arterial infusion of oxaliplatin and oral capecitabine, with or without intravenous bevacizumab, in patients with advanced cancer and predominant liver involvement

scientific article published on 04 September 2018

Aberrations in the epidermal growth factor receptor gene in 958 patients with diverse advanced tumors: implications for therapy.

scientific article

Advanced gynecologic malignancies treated with a combination of the VEGF inhibitor bevacizumab and the mTOR inhibitor temsirolimus

scientific article

Advances in HER2-Targeted Therapy: Novel Agents and Opportunities Beyond Breast and Gastric Cancer

scientific article published on 15 November 2018

Author Correction: HER kinase inhibition in patients with HER2- and HER3-mutant cancers

scientific article published on 01 February 2019

BRAF inhibitor dabrafenib in patients with metastatic BRAF-mutant thyroid cancer

scientific article

Body composition and survival in the early clinical trials setting.

scientific article published on 15 July 2013

Cancer-Related Internet Use and its Association with Patient Decision Making and Trust in Physicians among Patients in an Early Drug Development Clinic (Preprint)

article

Characteristics and outcomes of patients with advanced sarcoma enrolled in early phase immunotherapy trials.

scientific article published on 19 December 2017

Clinical pharmacodynamic/exposure characterisation of the multikinase inhibitor ilorasertib (ABT-348) in a phase 1 dose-escalation trial.

scientific article

Co-administration of vismodegib with rosiglitazone or combined oral contraceptive in patients with locally advanced or metastatic solid tumors: a pharmacokinetic assessment of drug-drug interaction potential

scientific article

Corrigendum to "Predicting outcomes in patients with advanced non-small cell lung cancer enrolled in early phase immunotherapy trials" [Lung Cancer 120 (June) (2018) 137-141]

scientific article published on 21 August 2019

Cutaneous Metastasis of a Mucoepidermoid Carcinoma of the Pancreas: First Reported Case

scientific article published on 29 March 2016

Cytokines Produced by Dendritic Cells Administered Intratumorally Correlate with Clinical Outcome in Patients with Diverse Cancers

article

Development of a prognostic scoring system for patients with advanced cancer enrolled in immune checkpoint inhibitor phase 1 clinical trials

scientific article published on 20 February 2018

Dose-finding study of hepatic arterial infusion of irinotecan-based treatment in patients with advanced cancers metastatic to the liver

scientific article

Dose-finding study of hepatic arterial infusion of oxaliplatin-based treatment in patients with advanced solid tumors metastatic to the liver

scientific article published on 11 November 2012

Dual inhibition of the vascular endothelial growth factor pathway: a phase 1 trial evaluating bevacizumab and AZD2171 (cediranib) in patients with advanced solid tumors

scientific article

Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Cervical Cancer: Results From the Phase II KEYNOTE-158 Study

scientific article published on 03 April 2019

Efficacy and safety of pembrolizumab for the treatment of advanced biliary cancer: Results from the KEYNOTE-158 and KEYNOTE-028 studies

scientific article published on 02 May 2020

Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair-Deficient Cancer: Results From the Phase II KEYNOTE-158 Study

scientific article published on 04 November 2019

Erratum to: First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors.

scientific article published on 7 April 2017

Evaluating for Pseudoprogression in Colorectal and Pancreatic Tumors Treated With Immunotherapy

scientific article published on 17 April 2018

Expanded analysis of secondary germline findings from matched tumor/normal sequencing identifies additional clinically significant mutations

scientific article published on 11 April 2019

Factors affecting symptom presentation in an early-phase clinical trials clinic patient population

scientific article published on 25 November 2019

Factors related to biopsy willingness in patients with advanced cancer in a phase 1 clinic for molecularly targeted therapy ⬇️

scientific article published on March 2, 2013

Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials

scientific article

First-in-Human Study of Mivebresib (ABBV-075), an Oral Pan-Inhibitor of Bromodomain and Extra Terminal Proteins, in Patients with Relapsed/Refractory Solid Tumors

scientific article published on 16 August 2019

First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors

scientific article

HER kinase inhibition in patients with HER2- and HER3-mutant cancers

scientific article published on 31 January 2018

HER2 somatic mutation analysis in breast cancer: correlation with clinicopathological features

scientific article published on 24 July 2019

IFN-γ-related mRNA profile predicts clinical response to PD-1 blockade.

scientific article

Impact of FDG PET Imaging for Expanding Patient Eligibility and Measuring Treatment Response in a Genome-Driven Basket Trial of the Pan-HER Kinase Inhibitor, Neratinib

scientific article published on 23 September 2019

Impact of microRNAs in resistance to chemotherapy and novel targeted agents in non-small cell lung cancer.

scientific article published on January 2014

Incidence of immune-related adverse events and its association with treatment outcomes: the MD Anderson Cancer Center experience

scientific article published on 21 November 2017

Liquid Biopsies Using Plasma Exosomal Nucleic Acids and Plasma Cell-Free DNA Compared with Clinical Outcomes of Patients with Advanced Cancers

scientific article published on 19 October 2017

Long-term overall survival and prognostic score predicting survival: the IMPACT study in precision medicine

scientific article published on 30 December 2019

Melanoma patients in a phase I clinic: molecular aberrations, targeted therapy and outcomes.

scientific article

Multiplex KRASG12/G13 mutation testing of unamplified cell-free DNA from the plasma of patients with advanced cancers using droplet digital polymerase chain reaction

scientific article published on 19 December 2016

Mutation-Enrichment Next-Generation Sequencing for Quantitative Detection of KRAS Mutations in Urine Cell-Free DNA from Patients with Advanced Cancers

scientific article published on 17 January 2017

Outcome analysis of Phase I trial patients with metastatic and/or mutant non-small cell lung cancer

Outcomes of patients with sarcoma enrolled in clinical trials of pazopanib combined with histone deacetylase, mTOR, Her2, or MEK inhibitors.

scientific article

PIK3CA mutation H1047R is associated with response to PI3K/AKT/mTOR signaling pathway inhibitors in early-phase clinical trials

scientific article published on 12 October 2012

Pembrolizumab for advanced prostate adenocarcinoma: findings of the KEYNOTE-028 study

scientific article published on 01 August 2018

Pembrolizumab for the Treatment of Advanced Salivary Gland Carcinoma: Findings of the Phase 1b KEYNOTE-028 Study

scientific article published on 16 February 2018

Pembrolizumab in patients with programmed death ligand 1-positive advanced ovarian cancer: Analysis of KEYNOTE-028

scientific article published on 03 December 2018

Phase 1 study of the combination of vemurafenib, carboplatin, and paclitaxel in patients With BRAF-mutated melanoma and other advanced malignancies

scientific article published on 01 November 2018

Phase I Study of LY2606368, a Checkpoint Kinase 1 Inhibitor, in Patients With Advanced Cancer

scientific article

Phase I clinical trial of bendamustine and bevacizumab for patients with advanced cancer

scientific article

Phase I clinical trial of combination imatinib and ipilimumab in patients with advanced malignancies

scientific article

Phase I clinical trial of lenalidomide in combination with 5-fluorouracil, leucovorin, and oxaliplatin in patients with advanced cancer

scientific article

Phase I clinical trial of lenalidomide in combination with sorafenib in patients with advanced cancer

scientific article

Phase I clinical trial of lenalidomide in combination with temsirolimus in patients with advanced cancer

scientific article

Phase I combination of pazopanib and everolimus in PIK3CA mutation positive/PTEN loss patients with advanced solid tumors refractory to standard therapy

scientific article

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy

scientific article

Phase I study of nab-paclitaxel, gemcitabine, and bevacizumab in patients with advanced cancers

scientific article published on 26 April 2018

Phase I study of pazopanib and vorinostat: a therapeutic approach for inhibiting mutant p53-mediated angiogenesis and facilitating mutant p53 degradation.

scientific article

Phase I study of the combination of crizotinib (as a MET inhibitor) and dasatinib (as a c-SRC inhibitor) in patients with advanced cancer

scientific article published on 19 October 2017

Phase I trial of MEK 1/2 inhibitor pimasertib combined with mTOR inhibitor temsirolimus in patients with advanced solid tumors

scientific article

Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with BRAFV600E Mutation

scientific article published on 11 October 2016

Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation

scientific article published on 05 July 2019

Photoallergic reaction in a patient receiving vandetanib for metastatic follicular thyroid carcinoma: a case report.

scientific article

Predicting outcomes in patients with advanced non-small cell lung cancer enrolled in early phase immunotherapy trials.

scientific article published on 11 April 2018

Prevalence of MDM2 amplification and coalterations in 523 advanced cancer patients in the MD Anderson phase 1 clinic

Response of Lymphangioleiomyomatosis to a Mammalian Target of Rapamycin Inhibitor (Temsirolimus) –Based Treatment ⬇️

scientific article published on January 24, 2011

Results of a phase 1 trial combining ridaforolimus and MK-0752 in patients with advanced solid tumours

scientific article

Retreatment with anti-EGFR based therapies in metastatic colorectal cancer: impact of intervening time interval and prior anti-EGFR response

scientific article published on 16 October 2015

STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trial

scholarly article by Matthew J Reilley et al published 16 November 2018 in Journal for Immunotherapy of Cancer

Safety and Antitumor Activity of Pembrolizumab in Patients with Estrogen Receptor‒Positive/Human Epidermal Growth Factor Receptor 2‒Negative Advanced Breast Cancer.

scientific article published on 20 March 2018

Safety and Efficacy of Pembrolizumab in Advanced, Programmed Death Ligand 1-Positive Cervical Cancer: Results From the Phase Ib KEYNOTE-028 Trial.

scientific article published on 2 November 2017

Safety and antitumor activity of the anti-PD-1 antibody pembrolizumab in patients with advanced colorectal carcinoma.

scientific article published on 28 December 2017

Safety and antitumor activity of the anti-PD-1 antibody pembrolizumab in patients with recurrent carcinoma of the anal canal.

scientific article

Salivary Duct Carcinoma: Targeting the Phosphatidylinositol 3-Kinase Pathway by Blocking Mammalian Target of Rapamycin With Temsirolimus ⬇️

scientific article published on August 15, 2011

T-Cell-Inflamed Gene-Expression Profile, Programmed Death Ligand 1 Expression, and Tumor Mutational Burden Predict Efficacy in Patients Treated With Pembrolizumab Across 20 Cancers: KEYNOTE-028

scientific article published on 13 December 2018

Target-based therapeutic matching in early-phase clinical trials in patients with advanced colorectal cancer and PIK3CA mutations

scientific article

Targeted methylation sequencing of plasma cell-free DNA for cancer detection and classification

scientific article published on 01 June 2018

The prognostic significance of left ventricular ejection fraction in patients with advanced cancer treated in phase I clinical trials.

scientific article published on January 2014

Paulina is supported by:

About Paulina

Help