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List of works by Connie Jimenez

An accurate paired sample test for count data

scientific article

Analysis of AKT and ERK1/2 protein kinases in extracellular vesicles isolated from blood of patients with cancer.

scientific article published on 8 December 2014

Analysis of SecA2-dependent substrates in Mycobacterium marinum identifies protein kinase G (PknG) as a virulence effector.

scientific article

Applications in brain proteomics: 8(th) HUPO Brain Proteome Project Workshop 7 October 2007, Seoul, Korea

scientific article published in May 2008

Automated serum peptide profiling using novel magnetic C18 beads off-line coupled to MALDI-TOF-MS

scientific article published on 11 May 2007

BRI2-BRICHOS is increased in human amyloid plaques in early stages of Alzheimer's disease

scientific article published on 13 January 2014

Can agrin cerebrospinal fluid concentration be used as an early biomarker for Alzheimer's disease?

scientific article published on 29 March 2015

Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles

scientific article published on 14 June 2018

Carcinoma origin dictates differential skewing of monocyte function

scientific article published on September 2012

Cell surface proteomics identifies glucose transporter type 1 and prion protein as candidate biomarkers for colorectal adenoma-to-carcinoma progression.

scientific article

Chemoenzymatic synthesis of multivalent neoglycoconjugates carrying the helminth glycan antigen LDNF.

scientific article published on 6 June 2009

Colorectal cancer candidate biomarkers identified by tissue secretome proteome profiling

scientific article published on 10 January 2014

Combined Expression of Plasma Thrombospondin-2 and CA19-9 for Diagnosis of Pancreatic Cancer and Distal Cholangiocarcinoma: A Proteome Approach

scientific article published on 14 January 2020

Comparative Proteomics of Colon Cancer Stem Cells and Differentiated Tumor Cells Identifies BIRC6 as a Potential Therapeutic Target ⬇️

scientific article published on July 25, 2011

Comparative protein profiling reveals minichromosome maintenance (MCM) proteins as novel potential tumor markers for meningiomas

scientific article

Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells.

scientific article

Comparison of the performance of two affinity depletion spin filters for quantitative proteomics of CSF: Evaluation of sensitivity and reproducibility of CSF analysis using GeLC-MS/MS and spectral counting

scientific article published on 29 March 2010

Composition of the type VII secretion system membrane complex.

scientific article published on 27 August 2012

Computational Analysis of Phosphoproteomics Data in Multi-Omics Cancer Studies

scientific article published on 01 September 2020

Consensus Guidelines for CSF and Blood Biobanking for CNS Biomarker Studies

scientific article

Consensus molecular subtype classification of colorectal adenomas

scientific article published on 31 August 2018

Correction: Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

scientific article

Current status of cancer proteomics, how far are we from clinical applications? ⬇️

scientific article published on 06 August 2010

DPHL: A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discovery

scientific article published on 11 August 2020

Detection of breast cancer by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry tissue and serum protein profiling

scientific article

Diagnostic cerebrospinal fluid biomarkers for Parkinson's disease: a pathogenetically based approach

scientific article published on 06 May 2010

Differential detergent extraction of mycobacterium marinum cell envelope proteins identifies an extensively modified threonine-rich outer membrane protein with channel activity.

scientific article published on March 2013

Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan

scientific article published on 01 April 2011

Endogeneous peptide profiling of cerebrospinal fluid by MALDI-TOF mass spectrometry: Optimization of magnetic bead-based peptide capture and analysis of preanalytical variables

scientific article published on 16 October 2007

EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF

scientific article published on 13 August 2018

Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria

scientific article published on 4 May 2015

Evaluation of potential circulating biomarkers for prediction of response to chemoradiation in patients with glioblastoma

scientific article published on 21 July 2016

Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients

scientific article published on 23 December 2013

Exosomal sorting of the viral oncoprotein LMP1 is restrained by TRAF2 association at signalling endosomes

scientific article published on 10 April 2015

Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis

scientific article

Exploration of the platelet proteome in patients with early-stage cancer.

scientific article published on 9 February 2018

Feasibility of label-free phosphoproteomics and application to base-line signaling of colorectal cancer cell lines.

scientific article published on April 2015

Feasibility of phosphoproteomics to uncover oncogenic signalling in secreted extracellular vesicles using glioblastoma-EGFRVIII cells as a model

scientific article published on 08 December 2020

Feasibility of urinary extracellular vesicle proteome profiling using a robust and simple, clinically applicable isolation method

scientific article published on 28 April 2017

GPx2 suppression of H2O2 stress links the formation of differentiated tumor mass to metastatic capacity in colorectal cancer

scientific article published on 26 September 2014

Gene set based integrated data analysis reveals phenotypic differences in a brain cancer model

scientific article

High-throughput and targeted in-depth mass spectrometry-based approaches for biofluid profiling and biomarker discovery

scientific article

Human Testis Phosphoproteome Reveals Kinases as Potential Targets in Spermatogenesis and Testicular Cancer

scientific article published on 25 January 2019

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

scientific article published on 12 April 2019

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

scientific article published on 24 May 2019

Identification of differentially expressed splice variants by the proteogenomic pipeline Splicify

scientific article

Identification of novel cerebrospinal fluid biomarker candidates for dementia with Lewy bodies: a proteomic approach

scientific article published on 18 June 2020

Influence of variations in sample handling on SELDI-TOF MS serum protein profiles for colorectal cancer

scientific article published on 01 June 2008

Integrating Phenotypic Search and Phosphoproteomic Profiling of Active Kinases for Optimization of Drug Mixtures for RCC Treatment

scientific article published on 21 September 2020

Interaction between KDELR2 and HSP47 as a Key Determinant in Osteogenesis Imperfecta Caused by Bi-allelic Variants in KDELR2

scientific article published on 09 October 2020

Intermittent administration of morphine alters protein expression in rat nucleus accumbens

scientific article published in March 2006

Label-free mass spectrometry-based proteomics for biomarker discovery and validation

scientific article published on May 2012

MALDI-TOF serum profiling using semiautomated serum peptide capture with magnetic reversed phase (C18) beads

scientific article

Mass spectrometry-based proteomics: from cancer biology to protein biomarkers, drug targets, and clinical applications

scientific article published on January 2014

MicroRNA-124 and -137 cooperativity controls caspase-3 activity through BCL2L13 in hippocampal neural stem cells

scientific article published on 24 July 2015

Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression

scientific article published on 30 August 2019

Molecular tests for colorectal cancer screening

scientific article published on March 2011

Multi-omics profile of the mouse dentate gyrus after kainic acid-induced status epilepticus

scientific article

Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis

scientific article published on 15 January 2018

Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes

scientific article published on 18 October 2016

Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study.

scientific article published on 21 November 2017

Novel diagnostic cerebrospinal fluid biomarkers for pathologic subtypes of frontotemporal dementia identified by proteomics.

scientific article published on 19 January 2016

Omics Analysis of Educated Platelets in Cancer and Benign Disease of the Pancreas

scientific article published on 29 December 2020

On the beta-binomial model for analysis of spectral count data in label-free tandem mass spectrometry-based proteomics

scientific article

Optimized Combination of HDACI and TKI Efficiently Inhibits Metabolic Activity in Renal Cell Carcinoma and Overcomes Sunitinib Resistance

scientific article published on 28 October 2020

Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment

scientific article published on 05 October 2020

PPIB mutations cause severe osteogenesis imperfecta

scientific article published on 24 September 2009

Peptidergic modulation of male sexual behavior inLymnaea stagnalis: structural and functional characterization of –FVamide neuropeptides ⬇️

scientific article published on December 1, 2003

Phosphotyrosine-based phosphoproteomics for target identification and drug response prediction in AML cell lines

scientific article published on 26 February 2020

Postoperative serum proteomic profiles may predict recurrence-free survival in high-risk primary breast cancer

scientific article

Prediction of outcome of non-small cell lung cancer patients treated with chemotherapy and bortezomib by time-course MALDI-TOF-MS serum peptide profiling

scientific article published on 3 September 2009

Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression

scientific article published on 13 January 2020

Proteome analysis of non-small cell lung cancer cell line secretomes and patient sputum reveals biofluid biomarker candidates for cisplatin response prediction

scientific article published on 30 January 2019

Proteomic Analysis of miR-195 and miR-497 Replacement Reveals Potential Candidates that Increase Sensitivity to Oxaliplatin in MSI/P53wt Colorectal Cancer Cells

scientific article published on 19 September 2019

Proteomic analysis of gemcitabine-resistant pancreatic cancer cells reveals that microtubule-associated protein 2 upregulation associates with taxane treatment

scientific article published on 10 May 2019

Proteomic profiling of Mycobacterium tuberculosis identifies nutrient-starvation-responsive toxin-antitoxin systems

scientific article published on 23 January 2013

Proteomics analysis of rat brain postsynaptic density. Implications of the diverse protein functional groups for the integration of synaptic physiology

scientific article

Proteomics in colorectal cancer translational research: biomarker discovery for clinical applications.

scientific article

Proteomics in studying cancer stem cell biology ⬇️

scientific article published on June 1, 2012

Proteomics of Colorectal Cancer in a Genomic Context: First Large-scale Mass Spectrometry-Based Analysis from the Cancer Genome Atlas

scientific article published on 26 February 2015

Proteomics of colorectal cancer: overview of discovery studies and identification of commonly identified cancer-associated proteins and candidate CRC serum markers.

scientific article published on 23 June 2010

Proteomics of genetically engineered mouse mammary tumors identifies fatty acid metabolism members as potential predictive markers for cisplatin resistance

scientific article published on 8 February 2013

Proteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancer

scientific article

Proteomics strategies for target identification and biomarker discovery in cancer.

scientific article published on January 2009

Proximal fluid proteome profiling of mouse colon tumors reveals biomarkers for early diagnosis of human colorectal cancer.

scientific article

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

scientific article published on 16 January 2018

Quantitative analysis of CDX2 protein expression improves its clinical utility as a prognostic biomarker in stage II and III colon cancer

scientific article published on 17 December 2020

Re-assessment of the high-grade serous ovarian cancer phosphoproteome - Identification of kinase candidates in TCGA tumors for future clinical intervention

Response and toxicity prediction by MALDI-TOF-MS serum peptide profiling in patients with non-small cell lung cancer

scientific article published on 4 April 2016

Secreted protein markers in oral squamous cell carcinoma (OSCC)

scientific article published on 08 February 2022

Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer

scientific article published on 23 August 2016

Specific chaperones for the type VII protein secretion pathway.

scientific article

Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies

scientific article published on 16 October 2020

Subnuclear proteomics in colorectal cancer: identification of proteins enriched in the nuclear matrix fraction and regulation in adenoma to carcinoma progression.

scientific article published on 20 January 2010

Support vector machine approach to separate control and breast cancer serum samples

scientific article

The Hippo Pathway Transducers YAP1/TEAD Induce Acquired Resistance to Trastuzumab in HER2-Positive Breast Cancer

scientific article published on 29 April 2020

The cancer proteomic landscape and the HUPO Cancer Proteome Project.

scientific article published on 25 January 2018

The cancer secretome, current status and opportunities in the lung, breast and colorectal cancer context ⬇️

scientific article published on January 31, 2013

The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies

scientific article published on 21 August 2019

The proteome of the locus ceruleus in Parkinson's disease: relevance to pathogenesis

scientific article published on 8 November 2011

The secretome of colon cancer stem cells contains drug-metabolizing enzymes

scientific article published on 5 July 2013

Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer

scientific article published on 01 June 2019

Ultramicroanalysis of Peptide Profiles in Biological Samples Using MALDI Mass Spectrometry ⬇️

scientific article published on 01 September 1998

Unravelling the nuclear matrix proteome

scientific article published on 14 October 2008

Urinary exosomal proteins as (pan-)cancer biomarkers: insights from the proteome

scientific article published on 01 July 2019

Vemurafenib plus cobimetinib in unresectable stage IIIc or stage IV melanoma: response monitoring and resistance prediction with positron emission tomography and tumor characteristics (REPOSIT): study protocol of a phase II, open-label, multicenter s

scientific article published on 15 September 2017

Whole gel processing procedure for GeLC-MS/MS based proteomics ⬇️

scientific article published on April 23, 2013

cNEUPRO: Novel Biomarkers for Neurodegenerative Diseases

scientific article

iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype

scientific article published on 12 August 2009

iq: an R package to estimate relative protein abundances from ion quantification in DIA-MS-based proteomics

scientific article published on 07 January 2020

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