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List of works by Paolo Simioni

"Hypocoagulable" thromboelastography profiles in patients with cyanotic congenital heart disease: facts or technical artifacts?

scientific article

A dysfunctional factor X (factor X San Giovanni Rotondo) present at homozygous and double heterozygous level: identification of a novel microdeletion (delC556) and missense mutation (Lys(408)-->Asn) in the factor X gene. A study of an Italian family

scientific article published on 01 February 2001

A highly polymorphic microsatellite in the factor V gene is an informative tool for the study of factor V-related disorders

scientific article published on 01 September 2001

A matrix-assisted laser desorption/ionization time-of-flight based method for screening the 1691G --> A mutation in the factor V gene.

scientific article

ABO blood groups and the risk of venous thrombosis in patients with inherited thrombophilia

scientific article published on 11 October 2012

Accuracy of two newly described D-dimer tests in patients with suspected deep venous thrombosis

scientific article published on 01 April 1997

Acquired risk factors for deep-vein thrombosis in symptomatic outpatients

scientific article published on 01 January 1994

Acute oppressive chest pain in a 66-year-old woman with a recent Amplatzer device closure of patent foramen ovale.

scientific article published in October 2007

Advances in understanding the bleeding diathesis in factor V deficiency.

scientific article published on 27 April 2009

Alterations in the coagulation profile in renal pig-to-monkey xenotransplantation.

scientific article published in March 2004

An antifibrinolytic mechanism describing the prothrombotic effect associated with factor VLeiden

scientific article published on 01 September 1996

An underestimated combination of opposites resulting in enhanced thrombotic tendency.

scientific article published on 16 June 2005

Anticardiolipin antibodies, functional protein S deficiency, and fetal loss

scientific article published on 01 January 1995

Anticoagulation for the treatment of thrombotic complications in patients with cirrhosis.

scientific article published on 27 June 2012

Antiplatelet therapy and other interventions after revascularisation procedures in patients with peripheral arterial disease: a meta-analysis.

scientific article published on April 2000

Appropriateness of choice and interpretation of tests for thrombophilic defects: a practical experience

scientific article published on 01 July 2003

Association between increased FVIIa-antithrombin complex/FVIIa ratio and pre-eclampsia

scientific article published on 16 April 2013

Bortezomib, C1-inhibitor and plasma exchange do not prolong the survival of multi-transgenic GalT-KO pig kidney xenografts in baboons

scientific article

Cell Therapy for Parkinson's Disease: A Translational Approach to Assess the Role of Local and Systemic Immunosuppression.

scientific article

Cerebral sinovenous thrombosis in children: thrombophilia and clinical outcome

scientific article published on 01 August 2007

Cerebral sinus venous thrombosis with parenchymal infarcts in a newborn with severe haemophilia A and subdural haematomas.

scientific article

Changing features of proximal vein thrombosis over time

scientific article published on 01 May 1994

Characterization of an apparently synonymous F5 mutation causing aberrant splicing and factor V deficiency.

scientific article

Childhood stroke associated with familial protein S deficiency.

scientific article published in May 1994

Circulating microparticles and the risk of thrombosis in inherited deficiencies of antithrombin, protein C and protein S.

scientific article

Circulating microparticles in carriers of factor V Leiden with and without a history of venous thrombosis

scientific article published on 26 July 2012

Circulating microparticles in carriers of prothrombin G20210A mutation

scientific article published on 08 May 2014

Circulating microparticles in umbilical cord blood in normal pregnancy and pregnancy with preeclampsia

scientific article published on 28 May 2015

Circulating microparticles of glial origin and tissue factor bearing in high-grade glioma: a potential prothrombotic role.

scientific article published on 27 June 2013

Clinical Data of Neonatal Systemic Thrombosis

scientific article

Clinical and laboratory expression of associated thrombophilic conditions (homozygous/heterozygous factor V Leiden mutation and heterozygous prothrombin variant 20210A) in an Italian family

scientific article published on 01 June 2000

Clotting inhibitors and fibronectin as potential markers in preeclampsia

scientific article published on 01 December 1994

Combined inherited protein S and heparin co-factor II deficiency in a patient with upper limb thrombosis: a family study

scientific article published on 01 July 1992

D-dimer evaluation of hemorrhagic orbital lymphangioma

scientific article published on 01 May 2010

Dalteparin for pregnant women with thrombophilia

scientific article published on 20 February 2015

Detection of IgG anti-Domain I beta2 Glycoprotein I antibodies by chemiluminescence immunoassay in primary antiphospholipid syndrome.

scientific article

Differential effects of high prothrombin levels on thrombin generation depending on the cause of the hyperprothrombinemia

scientific article published on 01 May 2007

Discrepancies between clotting and amidolytic assay in congenital clotting disorders

scientific article published on 01 August 1990

Duration of anticoagulation and risk of recurrent thromboembolism in carriers of factor V Leiden or prothrombin mutation

scientific article published on 01 October 2008

Dynamics of circulating microparticles in obesity after weight loss.

scientific article published on 2 February 2016

Early cerebral sinovenous thrombosis in a child with acute lymphoblastic leukemia carrying the prothrombin G20210A variant: a case report and review of the literature.

scientific article

Effect on thrombin generation of the "in vitro" addition of low-dose LMWH to plasma of healthy pregnant and nonpregnant women

scientific article published on 01 June 2012

Effects of Long-term Administration of High-dose Recombinant Human Antithrombin in Immunosuppressed Primate Recipients of Porcine Xenografts

scientific article published on 01 November 2005

Effects of long-term administration of recombinant human protein C in xenografted primates

scientific article published on 01 January 2011

Endocytosis of exogenous factor V by ex-vivo differentiated megakaryocytes from patients with severe parahaemophilia

scientific article published on 22 July 2016

Endothelial, platelet, and tissue factor-bearing microparticles in cancer patients with and without venous thromboembolism

scientific article published on 22 January 2011

Evaluation of a procoagulant phospholipid functional assay as a routine test for measuring circulating microparticle activity

scientific article published on 01 July 2014

Evaluation of activated protein C resistance in stored plasma

scientific article published on 01 May 1994

Expression of the normal factor V allele modulates the APC resistance phenotype in heterozygous carriers of the factor V Leiden mutation

scientific article published on 01 December 2005

Factor IX activity/antigen ratio and the risk of first unprovoked venous thromboembolism

scientific article published on 28 February 2013

Factor IX-Padua enhances the fibrinolytic resistance of plasma clots

scientific article published on 17 October 2013

Factor V Leiden is associated with more distal location of deep vein thrombosis of the leg

scientific article published on 25 December 2007

Factor V Leiden pseudo-homozygotes have a more pronounced hypercoagulable state than factor V Leiden homozygotes

scientific article published on 01 April 2011

Factor VIIa-AT complex plasma levels and arterial thrombosis

scientific article published on 11 October 2011

Factor VIIa-antithrombin complexes in children with ischemic stroke

scientific article published on 25 June 2011

Factor VIIa-antithrombin complexes in patients with arterial and venous thrombosis

scientific article published on 29 April 2010

Factor VIIa-antithrombin complexes plasma levels in cancer patients with and without thrombosis

scientific article published on 22 March 2012

Fibrinogen γ' increases the sensitivity to activated protein C in normal and factor V Leiden plasma

scientific article published on 20 June 2014

Fibronectin and antithrombin as markers of pre-eclampsia in pregnancy

scientific article published on 01 December 1996

Folate status and homocysteine level in Italian patients aged under 60 on oral anticoagulant therapy

scientific article

Freedom solo stentless aortic valve: quantitative and qualitative assessment of thrombocytopenia

scientific article published on 31 October 2011

Gender and the risk of venous thromboembolism.

scientific article

Genetic modulation of the FV(Leiden)/normal FV ratio and risk of venous thrombosis in factor V Leiden heterozygotes

scientific article published on 01 January 2012

Hemorrhagic and thrombotic disorders due to factor V deficiencies and abnormalities: an updated classification

scientific article published on 01 March 1998

Hereditary and acquired protein S deficiencies are associated with low TFPI levels in plasma

scientific article published on 30 November 2009

Heterozygous carrier of G20210A prothrombin mutation used oral contraceptive treatment for 23 years without thrombotic events, and developed cerebral venous thrombosis 1 month after resumption of the medication at the age of 50

scientific article published on 01 March 2001

Heterozygous protein C deficiency associated with multiple congenital hemangiomas--a case report

scientific article published on 01 April 1991

High dose of human plasma-derived FVIII-VWF as first-line therapy in patients affected by acquired haemophilia A and concomitant cardiovascular disease: four case reports and a literature review.

scientific article published on 11 October 2012

High prevalence of inherited thrombophilia in 'presumed peri-neonatal' ischemic stroke.

scientific article published on 19 November 2007

Homozygous F5 deep-intronic splicing mutation resulting in severe factor V deficiency and undetectable thrombin generation in platelet-rich plasma

scientific article published on 01 May 2011

Hypercoagulability detected by circulating microparticles in patients with hepatocellular carcinoma and cirrhosis.

scientific article

Hypercoagulability detected by whole blood thromboelastometry (ROTEM®) and impedance aggregometry (MULTIPLATE®) in obese patients

scientific article published on 07 January 2015

Hypercoagulability in overweight and obese subjects who are asymptomatic for thrombotic events

scientific article published on 16 October 2014

Identification of a novel frameshift mutation causing a premature stop codon in a young Nigerian man with type I antithrombin deficiency.

scientific article published on 18 February 2013

Impact of inherited thrombophilia on venous thromboembolism in children: a systematic review and meta-analysis of observational studies.

scientific article published on 08 September 2008

Impact of thrombophilia on risk of arterial ischemic stroke or cerebral sinovenous thrombosis in neonates and children: a systematic review and meta-analysis of observational studies.

scientific article

In vitro and in vivo effects of the carbon monoxide-releasing molecule, CORM-3, in the xenogeneic pig-to-primate context.

scientific article published in March 2009

Incidence of venous thromboembolism in asymptomatic family members who are carriers of factor V Leiden: a prospective cohort study.

scientific article published in March 2002

Increased anticoagulant response to low‐molecular‐weight heparin in plasma from patients with advanced cirrhosis ⬇️

scientific article published on September 1, 2012

Increased thrombin generation in liver transplant recipients: does immunosuppressive therapy play a role?

scientific article published on 01 March 2011

Increased tissue factor-initiated prothrombin activation as a result of the Arg506 --> Gln mutation in factor VLEIDEN

scientific article

Influence of proband's characteristics on the risk for venous thromboembolism in relatives with factor V Leiden or prothrombin G20210A polymorphisms.

scientific article published on 2 August 2013

Influence of single nucleotide polymorphisms on thrombin generation in factor V Leiden heterozygotes.

scientific article

Inherited thrombophilia and venous thromboembolism

scientific article published on 01 October 2006

Levels of angiogenic proteins in plasma and platelets are not different between patients with hepatitis B/C-related cirrhosis and patients with cirrhosis and hepatocellular carcinoma

scientific article published on 02 October 2014

Life-threatening coagulopathy and hypofibrinogenaemia induced by tigecycline in a patient with advanced liver cirrhosis

scientific article

Long-term use of oral contraceptive therapy in women with the prothrombin 20210 G-A polymorphism without thrombotic complications: a study of 13 women (12 heterozygotes and 1 homozygote)

scientific article published on 01 May 2001

Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency.

scientific article published on 11 August 2008

Management of severe bleeding in a ruptured extrauterine pregnancy: a theragnostic approach.

scientific article published in March 2014

Megakaryocytes endocytose and subsequently modify human factor V in vivo to form the entire pool of a unique platelet-derived cofactor

scientific article published on 01 March 2005

Microparticles as biomarkers of venous thromboembolic events

scientific article published on 24 June 2016

New Prothrombin Mutation (Arg596Trp, Prothrombin Padua 2) Associated With Venous Thromboembolism

scientific article

No evidence for increased platelet activation in patients with hepatitis B- or C-related cirrhosis and hepatocellular carcinoma.

scientific article published on 23 November 2014

Obstetric complications and pregnancy-related venous thromboembolism: The effect of low-molecular-weight heparin on their prevention in carriers of factor V Leiden or prothrombin G20210A mutation

scientific article published on 25 January 2012

Origin and levels of circulating microparticles in normal pregnancy: A longitudinal observation in healthy women.

scientific article published on 12 June 2015

Outcome of long-term prophylaxis after cerebral hemorrhage in a patient with severe hemophilia B.

scientific article published on 15 November 2010

Paediatric arterial ischaemic stroke and cerebral sinovenous thrombosis. First report from the Italian Registry of Pediatric Thrombosis (R. I. T. I., Registro Italiano Trombosi Infantili).

scientific article published on 12 March 2015

Perioperative coagulation assessment of patients undergoing major elective orthopedic surgery.

scientific article published on 7 March 2016

Phenotype and genotype expression in pseudohomozygous R2 factor V

scientific article published on 01 September 2001

Platelet factor V levels in moderate to severe congenital factor V deficiency.

scientific article published on 19 December 2011

Procoagulant activity in children with community acquired pneumonia, pleural effusion and empyema

scientific article published on 01 May 2008

Promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene: a novel risk factor for arterial ischemic stroke among young adults and children.

scientific article published on 22 November 2006

Prospective evaluation of anticoagulation and transjugular intrahepatic portosystemic shunt for the management of portal vein thrombosis in cirrhosis.

scientific article published on 21 March 2012

Prothrombin and the prothrombin 20210 G to A polymorphism: their relationship with hypercoagulability and thrombosis.

scientific article

Prothrombin antigen levels in symptomatic and asymptomatic carriers of the 20210A prothrombin variant

scientific article published on 01 December 1998

Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis.

scientific article

Reference values for thromboelastometry (ROTEM®) in cynomolgus monkeys (Macaca fascicularis).

scientific article published on 11 August 2010

Reprint of: Factor VIIa-AT complex plasma levels and arterial thrombosis

scientific article published on 01 August 2012

Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms

scientific article published on 27 October 2009

Reversal of hypercoagulability in patients with HCV-related cirrhosis after treatment with direct-acting antivirals

scientific article published on 21 May 2018

Risk of recurrent venous thromboembolism and thrombophilia: does discrepancy make complexity or vice versa?

scientific article published on 01 January 2003

Role of factor V Leiden polymorphism or G20210A prothrombin variant in patients with sudden sensorineural hearing loss: a meta-analysis of the literature

scientific article published on 13 December 2014

Screening for thrombophilia and antithrombotic prophylaxis in pregnancy: Guidelines of the Italian Society for Haemostasis and Thrombosis (SISET).

scientific article published on 11 August 2009

Screening for thrombophilia in children: a puzzling decision with unclear implications

scientific article published on 01 July 2004

Secondary parenchymal and vascular changes after middle cerebral artery stroke in children.

scientific article published on 3 August 2013

Selective modulation of protein C affinity for EPCR and phospholipids by Gla domain mutation.

scientific article published in January 2005

Sex-related type of venous thromboembolism in patients with and without thrombophilia

scientific article published on 01 July 2009

Short-term exposure to high levels of air pollution (nickel) and the risk of acute unprovoked proximal deep vein thrombosis in the legs

scientific article published on 08 December 2015

Short-term exposure to high levels of air pollution as a risk factor for acute isolated pulmonary embolism

scientific article published on 14 May 2014

Soluble endothelial protein C receptor (sEPCR) levels and venous thromboembolism in carriers of two dysfunctional protein C variants

scientific article published on 01 January 2006

Studies on coagulation incompatibilities for xenotransplantation

scientific article published on 01 January 2012

Synergistic antitumour activity of RAF265 and ZSTK474 on human TT medullary thyroid cancer cells

scientific article

The Coagulative Profile of Cyanotic Children Undergoing Cardiac Surgery: The Role of Whole Blood Preoperative Thromboelastometry on Postoperative Transfusion Requirement.

scientific article published on 27 November 2015

The G20210A prothrombin gene mutation: is there room for screening families?

scientific article published on 01 August 2004

The G20210A prothrombin variant and the risk of venous thromboembolism or fetal loss in pregnant women: a family study.

scientific article

The Risk of Recurrent Venous Thromboembolism in Patients with an Arg506→Gln Mutation in the Gene for Factor V (Factor V Leiden)

article

The antiproliferative effects of ouabain and everolimus on adrenocortical tumor cells

scientific article published on 24 October 2013

The biological inertia of coumarin-induced pre-factors (so called PIVKAs)

scientific article published on 01 December 1991

The clinical performance of a chemiluminescent immunoassay in detecting anti-cardiolipin and anti-β2 glycoprotein I antibodies. A comparison with a homemade ELISA method

scientific article published on 01 June 2015

The efficacy and the risk of immunogenicity of FIX Padua (R338L) in hemophilia B dogs treated by AAV muscle gene therapy.

scientific article

The hazard of comparing apples and oranges: the proper indication for the use of recombinant activated clotting factor VII in cardiac surgery

scientific article published on 01 December 2011

The incidence of venous thromboembolism in thrombophilic children: a prospective cohort study

scientific article published on 01 October 2002

The long term clinical course of acute deep vein thrombosis of the arm: prospective cohort study

scientific article (publication date: 28 August 2004)

The molecular genetics of familial venous thrombosis

scientific article published on 01 September 1999

The risk of cancer progression in women with gynecological malignancies and thrombophilic polymorphisms: a pilot case-control study

scientific article

The risk of recurrent venous thromboembolism after discontinuing anticoagulation in patients with acute proximal deep vein thrombosis or pulmonary embolism. A prospective cohort study in 1,626 patients

scientific article published on 01 February 2007

The role of antiphospholipid antibodies toward the protein C/protein S system in venous thromboembolic disease

scientific article published on 01 September 2009

Thrombin activatable fibrinolysis inhibitor in cancer patients with and without venous thromboembolism.

scientific article published on 9 September 2013

Thrombin generation in Cushing's Syndrome: do the conventional clotting indices tell the whole truth?

scientific article published on 01 February 2014

Thrombin generation-based assays to measure the activity of the TFPI-protein S pathway in plasma from normal and protein S-deficient individuals.

scientific article published on 17 January 2010

Thromboelastographic evaluation of coagulative profiles in pig-to-monkey kidney xenotransplantation.

scientific article published on 14 February 2013

Thromboelastometry profiles in patients undergoing thrombolytic therapy for acute ischaemic stroke

scientific article published on 11 February 2016

Thromboelastometry-guided therapy of massive gastrointestinal bleeding in a 12-year old boy with severe Graft-versus-Host disease

scientific article

Thrombophilia as a predictor of persistent residual vein thrombosis.

scientific article

Thrombophilic risk of individuals with rare compound factor V Leiden and prothrombin G20210A polymorphisms: an international case series of 100 individuals

scientific article published on 16 January 2016

Thrombophilic screening in young patients (< 40 years) with idiopathic ischemic stroke: a controlled study

scientific article

Thrombosis and thrombophilia in children: a systematic review.

scientific article

Thrombosis risk in purely obstetric APS ⬇️

scientific article published on March 15, 2012

Two additional homozygous patients for the 20210 prothrombin polymorphism with no venous thrombosis

scientific article published on 01 December 1999

Upper extremity deep vein thrombosis

scientific article published on 26 September 2009

Varicella and stroke in children: good outcome without steroids

scientific article published on 15 December 2010

Whole blood coagulation assessment using rotation thrombelastogram thromboelastometry in patients with acute deep vein thrombosis

scientific article published on 01 July 2008

Whole blood rotation thrombelastometry in subjects undergoing vitamin K antagonist treatment: hypo- or hypercoagulable profiles?

scientific article published on 04 June 2008

Whole blood rotation thromboelastometry (ROTEM®) profiles in subjects with non-neoplastic portal vein thrombosis.

scientific article published on 28 June 2013

Whole blood thromboelastometry profiles in women with preeclampsia

scientific article published on 18 March 2015

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