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List of works by Wael Y Mansour

5-Azacitidine Exerts Prolonged Pro-Apoptotic Effects and Overcomes Cisplatin-Resistance in Non-Seminomatous Germ Cell Tumor Cells ⬇️

scientific article published on 21 December 2018

5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair

scientific article published on May 2015

A functional ex vivo assay to detect PARP1-EJ repair and radiosensitization by PARP-inhibitor in prostate cancer.

scientific article published on 5 January 2019

BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy.

scientific article published on 8 March 2018

DNA Repair.

scientific article published in January 2016

Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair

scientific article

Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer.

scientific article published on 27 May 2016

Functional crosstalk between DNA damage response proteins 53BP1 and BRCA1 regulates double strand break repair choice.

scientific article published on 23 November 2015

High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation

scientific article published on 28 August 2015

Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1.

scientific article

Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells

scientific article

Interplay between Epigenetics, Expression of Estrogen Receptor- α, HER2/ERBB2 and Sensitivity of Triple Negative Breast Cancer Cells to Hormonal Therapy

scientific article published on 21 December 2018

Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness

scientific article published on 5 September 2016

Loss of PTEN-assisted G2/M checkpoint impedes homologous recombination repair and enhances radio-curability and PARP inhibitor treatment response in prostate cancer.

scientific article

PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response

scientific article published on 19 January 2016

The absence of Ku but not defects in classical non-homologous end-joining is required to trigger PARP1-dependent end-joining

scientific article published on 7 November 2013

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