List of works - Hon-Cheong So

10-year outcome study of an early intervention program for psychosis compared with standard care service.

scientific article

A unifying framework for evaluating the predictive power of genetic variants based on the level of heritability explained

scientific article

ASPM-lexical tone association in speakers of a tone language: Direct evidence for the genetic-biasing hypothesis of language evolution

scientific article published on 27 May 2020

Admission Rates and Psychiatric Beds in Hong Kong, 1999–2014: A Population-Based Study

scientific article published on 01 May 2016

An association study of RGS4 polymorphisms with clinical phenotypes of schizophrenia in a Chinese population

article

Analysis of genome-wide association data highlights candidates for drug repositioning in psychiatry

scientific article published on 14 August 2017

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Causal relationships between blood lipids and depression phenotypes: A Mendelian randomization analysis

Causal relationships between blood lipids and depression phenotypes: a Mendelian randomisation analysis

scientific article published on 24 April 2020

Common variants on Xq28 conferring risk of schizophrenia in Han Chinese

scientific article

Differential associations of depression-related phenotypes with cardiometabolic risks: Polygenic analyses and exploring shared genetic variants and pathways

scientific article published on 06 December 2018

Differential associations of various depression-related phenotypes with cardiometabolic risks: Identification of shared genetic factors and implications for drug repositioning

Drug repositioning for schizophrenia and depression/anxiety disorders: A machine learning approach leveraging expression data

scientific article published on 16 July 2018

Effect size measures in genetic association studies and age-conditional risk prediction

scientific article published on 13 September 2010

Estimating the total number of susceptibility variants underlying complex diseases from genome-wide association studies.

scientific article

Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases

scientific article published on 03 March 2011

Exploring Diseases/Traits and Blood Proteins Causally Related to Expression of ACE2, the Putative Receptor of SARS-CoV-2: A Mendelian Randomization Analysis Highlights Tentative Relevance of Diabetes-Related Traits

scientific article published on 19 May 2020

Exploring repositioning opportunities and side-effects of statins: a Mendelian randomization study of HMG-CoA reductase inhibition with 55 complex traits

Exploring shared genetic bases and causal relationships of schizophrenia and bipolar disorder with 28 cardiovascular and metabolic traits

scientific article published on 26 July 2018

Exploring the predictive power of polygenic scores derived from genome-wide association studies: a study of 10 complex traits

scientific article published on 8 January 2017

Genetics of schizophrenia spectrum disorders: looking back and peering ahead

article

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.

scientific article

Implications of de novo mutations in guiding drug discovery: A study of four neuropsychiatric disorders

scientific article published on 14 December 2018

Improving polygenic risk prediction from summary statistics by an empirical Bayes approach

scientific article published on February 2017

Leveraging genome-wide association and clinical data in revealing schizophrenia subgroups

scientific article published on 22 September 2018

Low copy number of the salivary amylase gene predisposes to obesity.

scientific article published on 30 March 2014

Multiple testing and power calculations in genetic association studies

scientific article published on January 2011

Newspaper coverage of mental illness in Hong Kong between 2002 and 2012: impact of introduction of a new Chinese name of psychosis.

scientific article published on 23 November 2015

Risk prediction of complex diseases from family history and known susceptibility loci, with applications for cancer screening

scientific article

Robust association tests under different genetic models, allowing for binary or quantitative traits and covariates

scientific article

SumVg: Total heritability explained by all variants in genome-wide association studies based on summary statistics with standard error estimates

article

Sustainability of treatment effect of a 3-year early intervention programme for first-episode psychosis

scientific article published on 6 April 2017

Translating GWAS Findings Into Therapies For Depression And Anxiety Disorders: Drug Repositioning Using Gene-Set Analyses Reveals Enrichment Of Psychiatric Drug Classes

article

Translating GWAS findings into therapies for depression and anxiety disorders: gene-set analyses reveal enrichment of psychiatric drug classes and implications for drug repositioning

scientific article published on 20 December 2018

Uncovering Clinical Risk Factors and Predicting Severe COVID-19 Cases Using UK Biobank Data: Machine Learning Approach

scientific article published on 30 September 2021

Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study

scientific article published on 26 May 2011

Using Drug Expression Profiles and Machine Learning Approach for Drug Repurposing

scientific article published on 01 January 2019

List of works by Hon-Cheong So

10-year outcome study of an early intervention program for psychosis compared with standard care service.

A unifying framework for evaluating the predictive power of genetic variants based on the level of heritability explained

ASPM-lexical tone association in speakers of a tone language: Direct evidence for the genetic-biasing hypothesis of language evolution

Admission Rates and Psychiatric Beds in Hong Kong, 1999–2014: A Population-Based Study

An association study of RGS4 polymorphisms with clinical phenotypes of schizophrenia in a Chinese population

Analysis of genome-wide association data highlights candidates for drug repositioning in psychiatry

Analysis of shared heritability in common disorders of the brain

Causal relationships between blood lipids and depression phenotypes: A Mendelian randomization analysis

Causal relationships between blood lipids and depression phenotypes: a Mendelian randomisation analysis

Common variants on Xq28 conferring risk of schizophrenia in Han Chinese

Differential associations of depression-related phenotypes with cardiometabolic risks: Polygenic analyses and exploring shared genetic variants and pathways

Differential associations of various depression-related phenotypes with cardiometabolic risks: Identification of shared genetic factors and implications for drug repositioning

Drug repositioning for schizophrenia and depression/anxiety disorders: A machine learning approach leveraging expression data

Effect size measures in genetic association studies and age-conditional risk prediction

Estimating the total number of susceptibility variants underlying complex diseases from genome-wide association studies.

Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases

Exploring Diseases/Traits and Blood Proteins Causally Related to Expression of ACE2, the Putative Receptor of SARS-CoV-2: A Mendelian Randomization Analysis Highlights Tentative Relevance of Diabetes-Related Traits

Exploring repositioning opportunities and side-effects of statins: a Mendelian randomization study of HMG-CoA reductase inhibition with 55 complex traits

Exploring shared genetic bases and causal relationships of schizophrenia and bipolar disorder with 28 cardiovascular and metabolic traits

Exploring the predictive power of polygenic scores derived from genome-wide association studies: a study of 10 complex traits

Genetics of schizophrenia spectrum disorders: looking back and peering ahead

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.

Implications of de novo mutations in guiding drug discovery: A study of four neuropsychiatric disorders

Implications of de novo mutations in guiding drug discovery: A study of four neuropsychiatric disorders

Improving polygenic risk prediction from summary statistics by an empirical Bayes approach

Leveraging genome-wide association and clinical data in revealing schizophrenia subgroups

Low copy number of the salivary amylase gene predisposes to obesity.

Multiple testing and power calculations in genetic association studies

Newspaper coverage of mental illness in Hong Kong between 2002 and 2012: impact of introduction of a new Chinese name of psychosis.

Risk prediction of complex diseases from family history and known susceptibility loci, with applications for cancer screening

Robust association tests under different genetic models, allowing for binary or quantitative traits and covariates

SumVg: Total heritability explained by all variants in genome-wide association studies based on summary statistics with standard error estimates

Sustainability of treatment effect of a 3-year early intervention programme for first-episode psychosis

Translating GWAS Findings Into Therapies For Depression And Anxiety Disorders: Drug Repositioning Using Gene-Set Analyses Reveals Enrichment Of Psychiatric Drug Classes

Translating GWAS findings into therapies for depression and anxiety disorders: gene-set analyses reveal enrichment of psychiatric drug classes and implications for drug repositioning

Uncovering Clinical Risk Factors and Predicting Severe COVID-19 Cases Using UK Biobank Data: Machine Learning Approach

Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study

Using Drug Expression Profiles and Machine Learning Approach for Drug Repurposing

When GWAS meets the Connectivity Map: drug repositioning for seven psychiatric disorders