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List of works by Kurt Bachman

A mechanism of T cell dependent selection of antigen engaged Germinal Center B cells ⬇️

journal article from 'PLOS ONE' published in 2018

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

scientific article

Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth

scientific article

Catalogue, cause, complexity and cure; the many uses of cancer genome sequence

scientific article published on 09 April 2010

Combination bortezomib and rituximab treatment affects multiple survival and death pathways to promote apoptosis in mantle cell lymphoma

scientific article published on January 2009

Combined Phosphatase and Tensin Homolog (PTEN) Loss and Fatty Acid Synthase (FAS) Overexpression Worsens the Prognosis of Chinese Patients with Hepatocellular Carcinoma ⬇️

scientific article published on August 10, 2012

Comprehensive Predictive Biomarker Analysis for MEK Inhibitor GSK1120212 ⬇️

scientific article published on December 14, 2011

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes.

scientific article

DNA methylation, chromatin inheritance, and cancer

scientific article

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

scientific article (publication date: 4 April 2002)

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

scientific article

De novo CpG island methylation in human cancer cells

scientific article

Decreased expression of the gut-enriched Krüppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients

scientific article

Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells

scientific article published on 20 October 2009

Deletion of p53 in human mammary epithelial cells causes chromosomal instability and altered therapeutic response

scientific article

Detection of Tumor PIK3CA Status in Metastatic Breast Cancer Using Peripheral Blood ⬇️

scientific article published on March 15, 2012

Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin

scientific article published on 26 June 2001

Duel nature of TGF-beta signaling: tumor suppressor vs. tumor promoter

scientific article

Enzymatic regional methylation assay: a novel method to quantify regional CpG methylation density

scientific article

Epigenetic control of gene expression in human cancer ⬇️

Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden

scientific article published on 4 December 2017

FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death ⬇️

scientific article published on October 31, 2011

High chromosome number in hematological cancer cell lines is a negative predictor of response to the inhibition of Aurora B and C by GSK1070916.

scientific article published on 15 July 2011

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

scientific article published in January 2003

Identification and validation of human DNA ligase inhibitors using computer-aided drug design

scientific article published on 17 July 2008

Identification of compounds that inhibit growth of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine-resistant cancer cells

scientific article published on June 2005

Interleukin-1 alpha mediates the growth proliferative effects of transforming growth factor-beta in p21 null MCF-10A human mammary epithelial cells

scientific article published on 17 April 2006

Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation

scientific article

Knockin of mutant PIK3CA activates multiple oncogenic pathways

scientific article

Lapatinib inhibits the growth of esophageal squamous cell carcinoma and synergistically interacts with 5-fluorouracil in patient-derived xenograft models

scientific article published on 27 May 2013

Loss and reduced expression of PTEN correlate with advanced-stage gastric carcinoma ⬇️

scientific article published on October 15, 2012

MCT-1 protein interacts with the cap complex and modulates messenger RNA translational profiles

scientific article published on September 2006

Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers

scientific article published in February 1999

Molecular target class is predictive of in vitro response profile

scientific article published on 20 April 2010

Mutation and copy number detection in human cancers using a custom genotyping assay ⬇️

scientific article published on May 7, 2011

Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells

scientific article

Mutation of the PIK3CA oncogene in human cancers

scientific article

P21 gene knock down does not identify genetic effectors seen with gene knock out.

scientific article published on July 2007

Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability

scientific article published on 22 June 2010

Subtype and pathway specific responses to anticancer compounds in breast cancer

scientific article published on 14 October 2011

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

scientific article (publication date: 1999)

The Methyl-CpG Binding Protein MBD1 Interacts with the p150 Subunit of Chromatin Assembly Factor 1 ⬇️

scientific article published on May 1, 2003

The PIK3CA gene is mutated with high frequency in human breast cancers.

scientific article

The RUNX2 transcription factor cooperates with the YES-associated protein, YAP65, to promote cell transformation

scientific article published on March 2007

The consensus coding sequences of human breast and colorectal cancers

scientific article

p21(WAF1/CIP1) mediates the growth response to TGF-beta in human epithelial cells

scientific article published in February 2004

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