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List of works by Christian K Holm

Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes

scientific article published on 12 October 2011

An innate antiviral pathway acting before interferons at epithelial surfaces

scientific article

Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

scientific article published on 21 October 2020

Corrigendum to “Interleukin-21 mRNA expression during virus infections” [Cytokine 33;2006:41–5]

scholarly article published in Cytokine

DNA recognition in immunity and disease ⬇️

scientific article published on 09 January 2013

Global transcriptional changes in response to cGAMP depend on STING in human THP-1 cells

scholarly article by Anne Louise Hansen et al published November 2018 in Cellular and Molecular Immunology

IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP

scientific article

Increased Interleukin 21 (IL-21) and IL-23 Are Associated with Increased Disease Activity and with Radiographic Status in Patients with Early Rheumatoid Arthritis

scientific article published on 03 August 2010

Increased plasma levels of IL-21 and IL-23 in spondyloarthritis are not associated with clinical and MRI findings

scientific article published on 30 November 2010

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses.

scientific article published on 19 February 2016

Interleukin-21 mRNA expression during virus infections

scientific article

Interleukin-21 receptor signalling is important for innate immune protection against HSV-2 infections.

scientific article

Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro

scientific article published on 25 November 2020

NKT cell activation by local α-galactosylceramide administration decreases susceptibility to HSV-2 infection

scientific article published on 21 January 2015

Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling

article published in the Proceedings of the National Academy of Sciences of the United States of America

Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming

scientific article published in Nature Communications

Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus

scientific article published on 9 June 2015

Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

scientific article published on 23 January 2013

SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

scientific article published on 02 October 2020

T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication

scientific article published on 3 January 2014

TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection

scientific article published on 01 March 2022

TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice

scientific article published on 19 March 2012

The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy

scientific article

Toll-like receptor 2 and 4 induced interleukin-19 dampens immune reactions and associates inversely with spondyloarthritis disease activity

scientific article

Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING.

scientific article published on 17 June 2012

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