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List of works by Craig R. Lee

Activation of the acute inflammatory response alters cytochrome P450 expression and eicosanoid metabolism

scientific article

Association between the EPHX2 p.Lys55Arg polymorphism and prognosis following an acute coronary syndrome

scientific article published on 07 August 2018

Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding

scientific article published on 23 January 2017

CYP2C19 Genotype-Guided Antiplatelet Therapy and 30-Day Outcomes After Percutaneous Coronary Intervention

scientific article published on 01 February 2019

CYP2C19-guided antiplatelet therapy: a cost-effectiveness analysis of 30-day and 1-year outcomes following percutaneous coronary intervention

scientific article published on 26 July 2017

CYP2J2 targeting to endothelial cells attenuates adiposity and vascular dysfunction in mice fed a high-fat diet by reprogramming adipocyte phenotype.

scientific article

Characterization of the Cytochrome P450 epoxyeicosanoid pathway in non-alcoholic steatohepatitis

scientific article published on 8 July 2016

Clinical Evidence Supports a Protective Role for CXCL5 in Coronary Artery Disease.

scientific article published on 15 November 2017

Clinical Utility of CYP2C19 Genotype-Guided Antiplatelet Therapy in Patients at Risk of Adverse Cardiovascular and Cerebrovascular Events: A Review of Emerging Evidence

scientific article published on 27 July 2020

Clinical Utility of CYP2C19 Genotyping to Guide Antiplatelet Therapy in Patients With an Acute Coronary Syndrome or Undergoing Percutaneous Coronary Intervention

scientific article published on 01 April 2019

Clinical outcomes of CYP2C19 genotype-guided antiplatelet therapy: existing evidence and future directions

article

Cost-effectiveness of CYP2C19-guided antiplatelet therapy in patients with acute coronary syndrome and percutaneous coronary intervention informed by real-world data

scientific article published on 11 February 2020

Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study

scientific article

Cytochrome P-450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-alpha via MAPK and PI3K/Akt signaling pathways.

scientific article

Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data.

scientific article

Cytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patients

scientific article

Cytochrome P450-derived epoxyeicosatrienoic acids and coronary artery disease in humans: a targeted metabolomics study

scientific article

Enalapril reverses high-fat diet-induced alterations in cytochrome P450-mediated eicosanoid metabolism.

scientific article published on 20 December 2011

Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice

scientific article

Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart

scientific article

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.

scientific article

Epoxyeicosanoids promote organ and tissue regeneration.

scientific article published on 29 July 2013

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice

scientific article published on 19 December 2011

Epoxyeicosatrienoic acids and cardioprotection: the road to translation

scientific article

Evaluation of cytochrome P4502C9 metabolic activity with tolbutamide in CYP2C91 heterozygotes.

scientific article published in November 2002

Frequency and clinical outcomes of CYP2C19 genotype-guided escalation and de-escalation of antiplatelet therapy in a real-world clinical setting

scientific article published on 18 July 2019

Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity

scientific article

Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study

journal article published in 2006

Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with forearm vasodilator responses in humans

scientific article

Genetic variation in the cytochrome P450 epoxygenase pathway and cardiovascular disease risk.

scientific article published on October 2007

High-impact articles related to the pharmacotherapeutic management of systolic heart failure.

scientific article

Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1).

scientific article

Implementation of inpatient models of pharmacogenetics programs.

scientific article published in December 2016

Multisite Investigation of Strategies for the Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy.

scientific article published on 26 December 2017

Oral Anticoagulant Use After Bariatric Surgery: A Literature Review and Clinical Guidance

scientific article

Polymorphisms in the transcription factor NRF2 and forearm vasodilator responses in humans.

scientific article published on August 2012

Precision Dosing: Public Health Need, Proposed Framework, and Anticipated Impact.

scientific article published on 10 August 2017

Projected impact of a multigene pharmacogenetic test to optimize medication prescribing in cardiovascular patients

scientific article published on 25 May 2018

Projected impact of pharmacogenomic testing on medications beyond antiplatelet therapy in percutaneous coronary intervention patients

scientific article published on 28 April 2020

Relation Between Digital Peripheral Arterial Tonometry and Brachial Artery Ultrasound Measures of Vascular Function in Patients With Coronary Artery Disease and in Healthy Volunteers ⬇️

scientific article published on December 6, 2011

Relation of sex to morbidity and mortality in patients with heart failure and reduced or preserved left ventricular ejection fraction

scientific article published on 01 June 2007

Relationship of serum digoxin concentration to mortality and morbidity in women in the digitalis investigation group trial: a retrospective analysis

scientific article published on 01 August 2005

Research Highlights: Highlights from the latest articles in personalized cardiovascular medicine

scientific article published on 01 June 2012

Resolvin Infectious Inflammation by Targeting the Host Response

scientific article

Role of endothelial soluble epoxide hydrolase in cerebrovascular function and ischemic injury.

scientific article

Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function

scientific article

Roles of chemokines CCL2 and CCL5 in the pharmacokinetics of PEGylated liposomal doxorubicin in vivo and in patients with recurrent epithelial ovarian cancer

scientific article published on 17 June 2015

Sex- and isoform-specific mechanism of neuroprotection by transgenic expression of P450 epoxygenase in vascular endothelium

scientific article

Soluble epoxide hydrolase null mice exhibit female and male differences in regulation of vascular homeostasis

scientific article

The IGNITE Pharmacogenetics Working Group: An Opportunity for Building Evidence with Pharmacogenetic Implementation in a Real-World Setting.

scientific article

The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease.

scientific article

The impact of ezetimibe on endothelial function and other markers of cardiovascular risk.

scientific article

Twenty-four hour tolbutamide plasma concentration as a phenotypic measure of CYP2C9 activity.

scientific article published on 4 May 2005

Urinary 11-dehydro-thromboxane B2 levels are associated with vascular inflammation and prognosis in atherosclerotic cardiovascular disease.

scientific article published on 16 November 2017

Vascular characterization of mice with endothelial expression of cytochrome P450 4F2.

scientific article

Vasopressin: a new target for the treatment of heart failure

scientific article

Warfarin dosing and the promise of pharmacogenomics.

scientific article published on January 2007

Warfarin initiation and the potential role of genomic-guided dosing.

scientific article published on November 2005

beta-Adrenergic receptor polymorphisms and responses during titration of metoprolol controlled release/extended release in heart failure.

scientific article published in March 2005

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