List of works - Maria Monti

A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6

scientific article

A new subfamily of fungal subtilases: structural and functional analysis of a Pleurotus ostreatus member

scientific article

A novel ErbB2 epitope targeted by human antitumor immunoagents

scientific article published on 01 March 2011

A nucleotide insertion and frameshift cause albumin Kenitra, an extended and O-glycosylated mutant of human serum albumin with two additional disulfide bridges

scholarly article by Lorenzo Minchiotti published in January 2001

Apolipoprotein A-I amyloidogenic variant L174S, expressed and isolated from stably transfected mammalian cells, is associated with fatty acids

scientific article published in February 2012

Chromobox protein homologue 7 protein, with decreased expression in human carcinomas, positively regulates E-cadherin expression by interacting with the histone deacetylase 2 protein

scientific journal article

Effects of a lipid environment on the fibrillogenic pathway of the N-terminal polypeptide of human apolipoprotein A-I, responsible for in vivo amyloid fibril formation

scientific article published on 25 February 2010

Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I

article published in 2018

Exploring the mechanism of formation of native-like and precursor amyloid oligomers for the native acylphosphatase from Sulfolobus solfataricus.

scientific article published in June 2006

Functional amyloids in insect immune response.

scientific article published on 22 December 2011

Functional proteomics

scientific article

HDAC6 mediates the acetylation of TRIM50.

scientific article published on 2 December 2013

Identification of p38 MAPK and JNK as new targets for correction of Wilson disease-causing ATP7B mutants

scientific article (publication date: June 2016)

Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation

scientific article

Interaction proteomics.

scientific article

Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function.

scientific article published on 2 August 2016

Limited Proteolysis Mass Spectrometry of Protein Complexes

article published in 2006

Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis.

scientific article

Mitochondrial chaperone Trap1 and the calcium binding protein Sorcin interact and protect cells against apoptosis induced by antiblastic agents.

scientific article published on 20 July 2010

Modulation of Amyloidogenic Peptide Aggregation by Photoactivatable CO-Releasing Ruthenium(II) Complexes

scientific article published on 29 July 2020

Molecular and functional analysis of the large 5' promoter region of CFTR gene revealed pathogenic mutations in CF and CFTR-related disorders

scientific article published on 5 March 2013

Multistep, sequential control of the trafficking and function of the multiple sulfatase deficiency gene product, SUMF1 by PDI, ERGIC-53 and ERp44.

scientific article published on 28 May 2008

Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes

scientific journal article

New label-free methods for protein relative quantification applied to the investigation of an animal model of Huntington Disease

scientific article published on 04 September 2020

Novel binding partners of Ldb1 are required for haematopoietic development

scientific article published on 15 November 2006

Osteopontin binds ICOSL promoting tumor metastasis

scientific article published on 26 October 2020

PED interacts with Rac1 and regulates cell migration/invasion processes in human non-small cell lung cancer cells.

scientific article published on October 2010

PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment

scientific article

Phosphorylation-regulated degradation of the tumor-suppressor form of PED by chaperone-mediated autophagy in lung cancer cells.

scientific article

Platinum(II) , Complexes Inhibit the Aggregation of Amyloid Model Systems

scientific article published in 2019

Protein conformational perturbations in hereditary amyloidosis: Differential impact of single point mutations in ApoAI amyloidogenic variants

scholarly article by Rita Del Giudice published in February 2016

Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis

scientific article

Proteomics of beta2-microglobulin amyloid fibrils.

scientific article

Purification, structural characterization, cloning and immunocytochemical localization of chemoreception proteins from Schistocerca gregaria

scientific article (publication date: June 1999)

Puzzle of protein complexes in vivo: a present and future challenge for functional proteomics

scientific article

Recombinant amyloidogenic domain of ApoA-I: Analysis of its fibrillogenic potential

article

Role of GALNT2 in the modulation of ENPP1 expression, and insulin signaling and action: GALNT2: a novel modulator of insulin signaling.

scientific article

S-Glutathionylation at Cys328 and Cys542 impairs STAT3 phosphorylation.

scientific article

S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia

scientific article published on 7 February 2018

Structural determinants in ApoA-I amyloidogenic variants explain improved cholesterol metabolism despite low HDL levels

scientific article published on 5 September 2017

Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum

scientific article

Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum

scientific article published on December 2016

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome

scientific article

The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP

scientific article

The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets

scientific article

The gene of an archaeal alpha-L-fucosidase is expressed by translational frameshifting

scientific article published on 18 August 2006

The molecular chaperone Hsp90 is a component of the cap-binding complex and interacts with the translational repressor Cup during Drosophila oogenesis

scientific article

The regions of the sequence most exposed to the solvent within the amyloidogenic state of a protein initiate the aggregation process.

scientific article published in February 2004

The two tryptophans of β2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure

scientific article

Topological investigation of amyloid fibrils obtained from beta2-microglobulin.

scientific article

Topology of the thyroid transcription factor 1 homeodomain-DNA complex.

scientific article

Towards the standardization of mitochondrial proteomics: the Italian mt-HPP initiative

scientific article

Transcriptional activity of the murine retinol-binding protein gene is regulated by a multiprotein complex containing HMGA1, p54 nrb/NonO, protein-associated splicing factor (PSF) and steroidogenic factor 1 (SF1)/liver receptor homologue 1 (LRH-1)

scientific journal article

Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi

scientific article published on 4 August 2013

What Antarctic Plants Can Tell Us about Climate Changes: Temperature as a Driver for Metabolic Reprogramming

scientific article published in 2021

List of works by Maria Monti

A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6

A new subfamily of fungal subtilases: structural and functional analysis of a Pleurotus ostreatus member

A novel ErbB2 epitope targeted by human antitumor immunoagents

A nucleotide insertion and frameshift cause albumin Kenitra, an extended and O-glycosylated mutant of human serum albumin with two additional disulfide bridges

Apolipoprotein A-I amyloidogenic variant L174S, expressed and isolated from stably transfected mammalian cells, is associated with fatty acids

Chromobox protein homologue 7 protein, with decreased expression in human carcinomas, positively regulates E-cadherin expression by interacting with the histone deacetylase 2 protein

Effects of a lipid environment on the fibrillogenic pathway of the N-terminal polypeptide of human apolipoprotein A-I, responsible for in vivo amyloid fibril formation

Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I

Exploring the mechanism of formation of native-like and precursor amyloid oligomers for the native acylphosphatase from Sulfolobus solfataricus.

Functional amyloids in insect immune response.

Functional proteomics

HDAC6 mediates the acetylation of TRIM50.

Identification of p38 MAPK and JNK as new targets for correction of Wilson disease-causing ATP7B mutants

Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation

Interaction proteomics.

Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function.

Limited Proteolysis Mass Spectrometry of Protein Complexes

Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis.

Mitochondrial chaperone Trap1 and the calcium binding protein Sorcin interact and protect cells against apoptosis induced by antiblastic agents.

Modulation of Amyloidogenic Peptide Aggregation by Photoactivatable CO-Releasing Ruthenium(II) Complexes

Molecular and functional analysis of the large 5' promoter region of CFTR gene revealed pathogenic mutations in CF and CFTR-related disorders

Multistep, sequential control of the trafficking and function of the multiple sulfatase deficiency gene product, SUMF1 by PDI, ERGIC-53 and ERp44.

Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes

New label-free methods for protein relative quantification applied to the investigation of an animal model of Huntington Disease

Novel binding partners of Ldb1 are required for haematopoietic development

Osteopontin binds ICOSL promoting tumor metastasis

PED interacts with Rac1 and regulates cell migration/invasion processes in human non-small cell lung cancer cells.

PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment

Phosphorylation-regulated degradation of the tumor-suppressor form of PED by chaperone-mediated autophagy in lung cancer cells.

Platinum(II) , Complexes Inhibit the Aggregation of Amyloid Model Systems

Protein conformational perturbations in hereditary amyloidosis: Differential impact of single point mutations in ApoAI amyloidogenic variants

Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis

Proteomics of beta2-microglobulin amyloid fibrils.

Purification, structural characterization, cloning and immunocytochemical localization of chemoreception proteins from Schistocerca gregaria

Puzzle of protein complexes in vivo: a present and future challenge for functional proteomics

Recombinant amyloidogenic domain of ApoA-I: Analysis of its fibrillogenic potential

Role of GALNT2 in the modulation of ENPP1 expression, and insulin signaling and action: GALNT2: a novel modulator of insulin signaling.

S-Glutathionylation at Cys328 and Cys542 impairs STAT3 phosphorylation.

S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia

Structural determinants in ApoA-I amyloidogenic variants explain improved cholesterol metabolism despite low HDL levels

Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum

Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome

The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP

The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets

The gene of an archaeal alpha-L-fucosidase is expressed by translational frameshifting

The molecular chaperone Hsp90 is a component of the cap-binding complex and interacts with the translational repressor Cup during Drosophila oogenesis

The regions of the sequence most exposed to the solvent within the amyloidogenic state of a protein initiate the aggregation process.

The two tryptophans of β2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure

Topological investigation of amyloid fibrils obtained from beta2-microglobulin.

Topology of the thyroid transcription factor 1 homeodomain-DNA complex.

Towards the standardization of mitochondrial proteomics: the Italian mt-HPP initiative

Transcriptional activity of the murine retinol-binding protein gene is regulated by a multiprotein complex containing HMGA1, p54 nrb/NonO, protein-associated splicing factor (PSF) and steroidogenic factor 1 (SF1)/liver receptor homologue 1 (LRH-1)

Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi

What Antarctic Plants Can Tell Us about Climate Changes: Temperature as a Driver for Metabolic Reprogramming