List of works by Richard A. Mathies

A digital microfluidic platform for the automation of quantitative biomolecular assays

scientific article

A forensic laboratory tests the Berkeley microfabricated capillary array electrophoresis device

scientific article

An in situ cell for characterization of solids by soft x-ray absorption

article published in 2004

An integrated microfluidic processor for single nucleotide polymorphism-based DNA computing

scientific article published on 11 August 2005

Analysis of carbonaceous biomarkers with the Mars Organic Analyzer microchip capillary electrophoresis system: Aldehydes and ketones ⬇️

scientific article published on October 21, 2010

Analysis of carbonaceous biomarkers with the Mars Organic Analyzer microchip capillary electrophoresis system: carboxylic acids

scientific article published on 26 July 2011

Analysis of neuroactive amines in fermented beverages using a portable microchip capillary electrophoresis system

scientific article published on 25 September 2007

Analysis of the mode-specific excited-state energy distribution and wavelength-dependent photoreaction quantum yield in rhodopsin

scientific article

Anharmonic vibrational calculations modeling the raman spectra of intermediates in the photoactive yellow protein (PYP) photocycle

scientific article

Anti-stokes Raman study of vibrational cooling dynamics in the primary photochemistry of rhodopsin

scientific article

Application of the Mars Organic Analyzer to nucleobase and amine biomarker detection.

scientific article

Capillary array electrophoresis: an approach to high-speed, high-throughput DNA sequencing

scientific article published in Nature

Capillary electrophoresis analysis of organic amines and amino acids in saline and acidic samples using the Mars organic analyzer

scientific article

Capillary electrophoresis chips with a sheath-flow supported electrochemical detection system

scientific article published in July 2004

Cellular microfabrication: observing intercellular interactions using lithographically-defined DNA capture sequences

scientific article

Characterization of a conical intersection in a charge-transfer dimer with two-dimensional time-resolved stimulated Raman spectroscopy.

scientific article published on 27 June 2014

Characterization of functional heme domains from soluble guanylate cyclase

scientific article published on December 2005

Characterization of nitrosoalkane binding and activation of soluble guanylate cyclase

scientific article

Chiral separation of fluorescamine-labeled amino acids using microfabricated capillary electrophoresis devices for extraterrestrial exploration

scientific article published in December 2003

Chromophore dynamics in the PYP photocycle from femtosecond stimulated Raman spectroscopy

scientific article

Conformational homogeneity and excited-state isomerization dynamics of the bilin chromophore in phytochrome Cph1 from resonance Raman intensities

scientific article published on 7 February 2012

Conical intersection dynamics of the primary photoisomerization event in vision

scientific article published on September 2010

Controlling Conformational Flexibility of an O 2 -Binding H-NOX Domain

scientific article

Critical Role of Methylammonium Librational Motion in Methylammonium Lead Iodide (CH3NH3PbI3) Perovskite Photochemistry.

scientific article published on 31 May 2017

DNA-barcode directed capture and electrochemical metabolic analysis of single mammalian cells on a microelectrode array

scientific article

Dependence of line shapes in femtosecond broadband stimulated Raman spectroscopy on pump-probe time delay

scientific article published on January 2005

Design and operation of a portable scanner for high performance microchip capillary array electrophoresis

scientific article

Detection of mitochondrial deoxyribonucleic acid alterations in urine from urothelial cell carcinoma patients

scientific article published on 30 August 2011

Determinants of the heme-CO vibrational modes in the H-NOX family

scientific article published on 11 July 2011

Development and evaluation of a microdevice for amino acid biomarker detection and analysis on Mars

scientific article

Development and multiplexed control of latching pneumatic valves using microfluidic logical structures

scientific article published on 6 April 2006

Development of a tunable femtosecond stimulated raman apparatus and its application to beta-carotene

scientific article

Difference Bands in Time-Resolved Femtosecond Stimulated Raman Spectra of Photoexcited Intermolecular Electron Transfer from Chloronaphthalene to Tetracyanoethylene.

scientific article published on 21 March 2018

Digitally programmable microfluidic automaton for multiscale combinatorial mixing and sample processing

scientific article

Direct attachment of microbial organisms to material surfaces through sequence-specific DNA hybridization

scientific article published on 19 March 2012

Direct cell surface modification with DNA for the capture of primary cells and the investigation of myotube formation on defined patterns

scientific article

Direct observation of anharmonic coupling in the time domain with femtosecond stimulated Raman scattering.

scientific article published on 15 June 2006

Direct observation of the ultrafast intersystem crossing in tris(2,2′-bipyridine)ruthenium(II) using femtosecond stimulated Raman spectroscopy

Disposable roll-to-roll hot embossed electrophoresis chip for detection of antibiotic resistance gene mecA in bacteria.

scientific article published on 29 November 2011

Electron Transfer Dynamics of Triphenylamine Dyes Bound to TiO2 Nanoparticles from Femtosecond Stimulated Raman Spectroscopy

article

End-to-end automated microfluidic platform for synthetic biology: from design to functional analysis

scientific article

Enhanced amine and amino acid analysis using Pacific Blue and the Mars Organic Analyzer microchip capillary electrophoresis system

scientific article published on April 2009

Evidence for a vibrational phase-dependent isotope effect on the photochemistry of vision

scientific article published on 19 March 2018

Excited-state structure and dynamics of cis- and trans-Azobenzene from resonance Raman intensity analysis

scientific article

Excited-state vibrational dynamics toward the polaron in methylammonium lead iodide perovskite.

scientific article

Exciton Mobility in Organic Photovoltaic Heterojunctions from Femtosecond Stimulated Raman.

scientific article published on 13 July 2015

Fabrication of high-quality glass microfluidic devices for bioanalytical and space flight applications

scientific article published on 27 August 2020

Feasibility of Detecting Bioorganic Compounds in Enceladus Plumes with the Enceladus Organic Analyzer

scientific article published on September 2017

Feasibility of Enceladus plume biosignature analysis: Successful capture of organic ice particles in hypervelocity impacts

scholarly article

Femtosecond Stimulated Raman Exposes the Role of Vibrational Coherence in Condensed-Phase Photoreactivity

scientific article published on 22 March 2016

Femtosecond Stimulated Raman Spectroscopy.

scientific article published on 26 February 2016

Femtosecond Time-Resolved Stimulated Raman Spectroscopy of the S(2) (1B(u)) Excited State of beta-Carotene

scientific article

Femtosecond Time-Resolved Stimulated Raman Spectroscopy: Application to the Ultrafast Internal Conversion in beta-Carotene

scientific article

Femtosecond broadband stimulated Raman spectroscopy: Apparatus and methods

scientific article

Femtosecond broadband stimulated Raman: a new approach for high-performance vibrational spectroscopy

scientific article

Femtosecond stimulated Raman spectroscopy

scientific article published on January 2007

Femtosecond stimulated Raman spectroscopy

scientific article published in September 2006

Femtosecond stimulated Raman study of excited-state evolution in bacteriorhodopsin

scientific article published on May 2005

Femtosecond time-resolved optical and Raman spectroscopy of photoinduced spin crossover: temporal resolution of low-to-high spin optical switching

scientific article published on 01 October 2008

Femtosecond time-resolved stimulated Raman reveals the birth of bacteriorhodopsin's J and K intermediates.

scientific article published in June 2009

Flowing liquid sample jet for resonance Raman and ultrafast optical spectroscopy

scientific article published in November 2003

Fluorescence energy transfer-labeled primers for high-performance forensic DNA profiling

scientific article published on June 2008

Fluorescence labeling methods for microchannel plate capillary electrophoresis DNA sizing

scientific article published on 01 January 2002

Fluoro derivatives of retinal illuminate the decisive role of the C(12)-H element in photoisomerization and rhodopsin activation

scientific article published in December 2009

Function of extracellular loop 2 in rhodopsin: glutamic acid 181 modulates stability and absorption wavelength of metarhodopsin II.

scientific article

High throughput DNA sequencing with a microfabricated 96-lane capillary array electrophoresis bioprocessor

scientific article

High-performance detection of somatic D-loop mutation in urothelial cell carcinoma patients by polymorphism ratio sequencing

scientific article published on 31 March 2016

High-performance single cell genetic analysis using microfluidic emulsion generator arrays

scientific article

High-temperature microfluidic synthesis of CdSe nanocrystals in nanoliter droplets

scientific article

High-throughput single copy DNA amplification and cell analysis in engineered nanoliter droplets

scientific article published on 15 April 2008

High-throughput single-strand conformation polymorphism analysis on a microfabricated capillary array electrophoresis device

scientific article published in May 2005

Homogeneity of phytochrome Cph1 vibronic absorption revealed by resonance Raman intensity analysis

scientific article

Homogeneous immunoassay for detection of TNT and its analogues on a microfabricated capillary electrophoresis chip

scientific article published in March 2003

Identification of hydroperoxy species as reaction intermediates in the electrochemical evolution of oxygen on gold

scientific article published in June 2010

Immunomagnetic bead-based cell concentration microdevice for dilute pathogen detection

scientific article published in December 2008

Improving efficiency of a small forensic DNA laboratory: validation of robotic assays and evaluation of microcapillary array device.

scientific article published on August 2005

Inline injection microdevice for attomole-scale sanger DNA sequencing

scientific article

Insights into the structural changes occurring upon photoconversion in the orange carotenoid protein from broadband two-dimensional electronic spectroscopy

scientific article published on 9 May 2014

Integrated DNA purification, PCR, sample cleanup, and capillary electrophoresis microchip for forensic human identification.

scientific article published on 4 February 2011

Integrated affinity capture, purification, and capillary electrophoresis microdevice for quantitative double-stranded DNA analysis

scientific article

Integrated capillary electrophoresis microsystem for multiplex analysis of human respiratory viruses

scientific article

Integrated capture, concentration, polymerase chain reaction, and capillary electrophoretic analysis of pathogens on a chip

scientific article

Integrated hydrogenated amorphous Si photodiode detector for microfluidic bioanalytical devices

scientific article published in October 2003

Integrated microfluidic bioprocessor for single-cell gene expression analysis

scholarly article

Integrated microfluidic bioprocessor for solid phase capture immunoassays

scientific article

Integrated microfluidic systems for high-performance genetic analysis

scientific article published on 24 August 2009

Integrated portable polymerase chain reaction-capillary electrophoresis microsystem for rapid forensic short tandem repeat typing.

scientific article

Integrated sample cleanup and capillary array electrophoresis microchip for forensic short tandem repeat analysis ⬇️

scientific article published on November 10, 2010

Integrated sample cleanup and microchip capillary array electrophoresis for high-performance forensic STR profiling

scientific article published in January 2012

Integrated sample cleanup-capillary electrophoresis microchip for high-performance short tandem repeat genetic analysis

scientific article

Lifting gate polydimethylsiloxane microvalves and pumps for microfluidic control

scientific article published in February 2012

Low frequency resonant impulsive Raman modes reveal inversion mechanism for azobenzene.

scientific article published in November 2013

Mapping GFP structure evolution during proton transfer with femtosecond Raman spectroscopy.

scientific article

Microchip bioprocessor for integrated nanovolume sample purification and DNA sequencing

scientific article

Microfabricated 384-lane capillary array electrophoresis bioanalyzer for ultrahigh-throughput genetic analysis

scientific article published in October 2002

Microfabricated bioprocessor for integrated nanoliter-scale Sanger DNA sequencing

scholarly article

Microfabricated linear hydrogel microarray for single-nucleotide polymorphism detection

scientific article published on 30 December 2011

Microfabricated two-dimensional electrophoresis device for differential protein expression profiling

scientific article published on 7 September 2007

Microfluidic System for Detection of Viral RNA in Blood Using a Barcode Fluorescence Reporter and a Photocleavable Capture Probe.

scientific article published on 26 October 2017

Microfluidic device for electric field-driven single-cell capture and activation

scientific article published in November 2005

Microfluidic devices for DNA sequencing: sample preparation and electrophoretic analysis

scientific article

Microfluidic hydrogel arrays for direct genotyping of clinical samples

scientific article published on 21 December 2015

Microfluidic linear hydrogel array for multiplexed single nucleotide polymorphism (SNP) detection

scientific article published on 23 February 2015

Microfluidic serial dilution circuit

scientific article published on November 2006

Microvalve Enabled Digital Microfluidic Systems for High Performance Biochemical and Genetic Analysis

scientific article

Millisecond kinetics of nanocrystal cation exchange using microfluidic X-ray absorption spectroscopy

scientific article

Minimizing inhibition of PCR-STR typing using digital agarose droplet microfluidics

scientific article

Modular integration of electronics and microfluidic systems using flexible printed circuit boards

scientific article published on 2 December 2009

Monitoring transient cell-to-cell interactions in a multi-layered and multi-functional allergy-on-a-chip system

scientific article published on 09 May 2019

Multichannel PCR-CE microdevice for genetic analysis

scientific article published in August 2006

Multichannel capillary electrophoresis microdevice and instrumentation for in situ planetary analysis of organic molecules and biomarkers

scientific article

Multichannel homogeneous immunoassay for detection of 2,4,6-trinitrotoluene (TNT) using a microfabricated capillary array electrophoresis chip

scientific article

Multichannel reverse transcription-polymerase chain reaction microdevice for rapid gene expression and biomarker analysis

scientific article

New strategies to detect life on Mars

Nitric oxide binding to prokaryotic homologs of the soluble guanylate cyclase beta1 H-NOX domain

scientific article published on 25 May 2006

Non-Bonded Interactions Drive the Sub-Picosecond Bilin Photoisomerization in the P(fr) State of Phytochrome Cph1.

scientific article published on 2 December 2015

Novel energy transfer fluorescence labeling cassette

scientific article published in February 2002

On the Feasibility of Informative Biosignature Measurements Using an Enceladus Plume Organic Analyzer

scholarly article

Optimally shaped narrowband picosecond pulses for femtosecond stimulated Raman spectroscopy.

scientific article published in September 2013

Organic amine biomarker detection in the Yungay region of the Atacama Desert with the Urey instrument

scientific article published in 2007

Origin of Negative and Dispersive Features in Resonance Femtosecond Stimulated Raman Spectroscopy

Origin of negative and dispersive features in anti-Stokes and resonance femtosecond stimulated Raman spectroscopy.

scientific article published in August 2008

PMMA/PDMS valves and pumps for disposable microfluidics

scientific article published on 20 August 2009

Photoactivated bioconjugation between ortho-azidophenols and anilines: a facile approach to biomolecular photopatterning

scientific article published on 29 August 2014

Photochemistry: A coherent picture of vision

scientific article published in November 2015

Photoexcited structural dynamics of an azobenzene analog 4-nitro-4'-dimethylamino-azobenzene from femtosecond stimulated Raman.

scientific article published on 28 February 2012

Picosecond Dynamics of G-Protein Coupled Receptor Activation in Rhodopsin from Time-Resolved UV Resonance Raman Spectroscopy ⬇️

scientific article published on May 13, 2003

Pneumatically actuated microvalve circuits for programmable automation of chemical and biochemical analysis

scientific article published on 11 February 2016

Polarization dependence of vibrational coupling signals in femtosecond stimulated Raman spectroscopy

scientific article published in September 2007

Polycyclic aromatic hydrocarbon analysis with the Mars organic analyzer microchip capillary electrophoresis system

scientific article published on January 2009

Polymerase chain reaction-capillary electrophoresis genetic analysis microdevice with in-line affinity capture sample injection

scientific article published in February 2009

Polymorphism ratio sequencing: a new approach for single nucleotide polymorphism discovery and genotyping

scientific article

Probing interfacial electron transfer in coumarin 343 sensitized TiO2 nanoparticles with femtosecond stimulated Raman

scientific article published in November 2009

Probing structural evolution along multidimensional reaction coordinates with femtosecond stimulated Raman spectroscopy

scientific article

Programmable cell adhesion encoded by DNA hybridization

scientific article published on January 2006

Rapid and Fully Microfluidic Ebola Virus Detection with CRISPR-Cas13a

scientific article published on 21 March 2019

Rapid and high-throughput forensic short tandem repeat typing using a 96-lane microfabricated capillary array electrophoresis microdevice

scientific article published in July 2006

Rapid determination of monozygous twinning with a microfabricated capillary array electrophoresis genetic-analysis device.

scientific article

Rapid fabrication of nickel molds for prototyping embossed plastic microfluidic devices

scientific article

Rapid on-column analysis of glucosamine and its mutarotation by microchip capillary electrophoresis

scientific article published on 21 August 2006

Reactive and unreactive pathways in a photochemical ring opening reaction from 2D femtosecond stimulated Raman.

scientific article

Real-time forensic DNA analysis at a crime scene using a portable microchip analyzer

scientific article

Resonance Raman Characterization of Tetracene Monomer and Nanocrystals: Excited State Lattice Distortions With Implications For Efficient Singlet Fission

scientific article published on 23 April 2019

Resonance Raman Spectra of an O2-Binding H-NOX Domain Reveal Heme Relaxation upon Mutation

Resonance Raman analysis of the mechanism of energy storage and chromophore distortion in the primary visual photoproduct

scientific article published in August 2004

Resonance Raman cross-sections and vibronic analysis of rhodamine 6G from broadband stimulated Raman spectroscopy

scientific article

Resonance Raman spectra of an O2-binding H-NOX domain reveal heme relaxation upon mutation

scientific article published on September 2009

Resonance Raman spectra of electrons solvated in liquid alcohols

scientific article published in March 2004

Retinal counterion switch in the photoactivation of the G protein-coupled receptor rhodopsin

scientific article

Science Objectives for Flagship-Class Mission Concepts for the Search for Evidence of Life at Enceladus

scientific article published in June 2022

Selected technologies for measuring acquired genetic damage in humans ⬇️

scientific article published on October 1, 2010

Self-assembled cellular microarrays patterned using DNA barcodes

scientific article published on 19 September 2007

Single cell measurement of telomerase expression and splicing using microfluidic emulsion cultures

scientific article published on 21 July 2015

Single molecule quantitation and sequencing of rare translocations using microfluidic nested digital PCR.

scientific article published on 19 July 2013

Single-cell forensic short tandem repeat typing within microfluidic droplets

scientific article published on 22 November 2013

Single-cell multiplex gene detection and sequencing with microfluidically generated agarose emulsions

scientific article published on January 2011

Size-Controlled Growth of CdSe Nanocrystals in Microfluidic Reactors

article published in 2003

Sparsely cross-linked "nanogel" matrixes as fluid, mechanically stabilized polymer networks for high-throughput microchannel DNA sequencing

scientific article

Spectroscopic characterization of the soluble guanylate cyclase-like heme domains from Vibrio cholerae and Thermoanaerobacter tengcongensis

scientific article

Structural and functional modularity of the orange carotenoid protein: distinct roles for the N- and C-terminal domains in cyanobacterial photoprotection

scientific article published on 7 January 2014

Structural dynamics of a noncovalent charge transfer complex from femtosecond stimulated Raman spectroscopy

scientific article published on 11 April 2012

Structural observation of the primary isomerization in vision with femtosecond-stimulated Raman

scientific article

Structure and dynamics of the solvated electron in alcohols from resonance Raman spectroscopy

scientific article

Structure of the aqueous solvated electron from resonance Raman spectroscopy: lessons from isotopic mixtures.

scientific article published in February 2003

Sulfate minerals and organic compounds on Mars

scholarly article

Supramolecular Ga4L6(12-) Cage Photosensitizes 1,3-Rearrangement of Encapsulated Guest via Photoinduced Electron Transfer.

scientific article published on 10 August 2015

Surface multiheme c-type cytochromes from Thermincola potens and implications for respiratory metal reduction by Gram-positive bacteria

scientific article published on 17 January 2012

The Urey instrument: an advanced in situ organic and oxidant detector for Mars exploration

scientific article

Theory of femtosecond stimulated Raman spectroscopy

scientific article published on August 2004

Time-resolved resonance Raman analysis of chromophore structural changes in the formation and decay of rhodopsin's BSI intermediate.

scientific article published in May 2002

Time-resolved resonance raman structural studies of the pB' intermediate in the photocycle of photoactive yellow protein

scientific article

Ultrafast excited-state isomerization in phytochrome revealed by femtosecond stimulated Raman spectroscopy ⬇️

scholarly article

Universal microfluidic automaton for autonomous sample processing: application to the Mars Organic Analyzer

scientific article published on 29 July 2013

Venus, an Astrobiology Target

scientific article published in October 2021

Vibrational Relaxation in beta-Carotene Probed by Picosecond Stokes and Anti-Stokes Resonance Raman Spectroscopy

scientific article published on June 2002

Vibrational structure of the S2 (1Bu) excited state of diphenyloctatetraene observed by femtosecond stimulated Raman spectroscopy

article

Wavepacket Splitting and Two-Pathway Deactivation in the Photoexcited Visual Pigment Isorhodopsin

scientific article published on 31 January 2014

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