List of works - Webster L Santos

A method for the deprotection of alkylpinacolyl boronate esters

scientific article

Branched Peptides: Acridine and Boronic Acid Derivatives as Antimicrobial Agents

scientific article published on 12 July 2017

Branched peptide boronic acids (BPBAs): a novel mode of binding towards RNA.

scientific article

Brønsted Base-Mediated Regio- and Stereoselective trans-Silaboration of Propargylamides: Access to 1,2-Vinylborasilanes

scientific article published on 8 September 2017

Catalytic, Transition-Metal-Free Semireduction of Propiolamide Derivatives: Scope and Mechanistic Investigation

scientific article published on 26 August 2020

Copper(II)-Catalyzed Silyl Conjugate Addition to α,β-Unsaturated Conjugated Compounds: Brønsted Base-Assisted Activation of Si–B Bond in Water

article

Copper(II)-catalyzed silylation of activated alkynes in water: diastereodivergent access to E- or Z-β-silyl-α,β-unsaturated carbonyl and carboxyl compounds

scientific article

Copper-boryl mediated organic synthesis

scientific article published on 01 October 2018

Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors

scientific article

Diboration of 3-substituted propargylic alcohols using a bimetallic catalyst system: access to (Z)-allyl, vinyldiboronates

scientific article published on 06 August 2020

Discovery of a Branched Peptide that Recognizes the Rev Response Element (RRE) RNA and Blocks HIV-1 Replication

article

Discovery of a Small Side Cavity in Sphingosine Kinase 2 that Enhances Inhibitor Potency and Selectivity

scientific article published on 28 January 2020

Drugging sphingosine kinases.

scientific article

Effect of alkyl chain length on sphingosine kinase 2 selectivity

scientific article

Fluorescence lifetime based characterization of active and tunable plasmonic nanostructures

scientific article published in August 2014

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane

scientific article

Impact of lithography on the fluorescence dynamics of self-assembled fluorophores

scientific article published on 01 June 2014

In Silico Characterization of Structural Distinctions between Isoforms of Human and Mouse Sphingosine Kinases for Accelerating Drug Discovery

scientific article published on 19 March 2019

Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop

scientific article

Interaction between human serum albumin and the felbamate metabolites 4-Hydroxy-5-phenyl-[1,3]oxazinan-2-one and 2-phenylpropenal

scientific article

Light-Directed Patchy Particle Fabrication and Assembly from Isotropic Silver Nanoparticles

scientific article published on 14 September 2017

Lipid phosphate phosphatase-1 expression in cancer cells attenuates tumor growth and metastasis in mice.

scientific article

Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent.

scientific article

Mapping targetable sites on human telomerase RNA pseudoknot/template domain using 2'-OMe RNA-interacting polynucleotide (RIPtide) microarrays

scientific article

Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice

scientific article published on 14 May 2020

Molecular recognition of a branched peptide with HIV-1 Rev Response Element (RRE) RNA

scientific article published on 07 March 2019

Multi-photon patterning of photoactive o-nitrobenzyl ligands bound to gold surfaces

scientific article published on 22 October 2018

N-Terminal peptidic boronic acids selectively inhibit human ClpXP.

scientific article

Plasmon-Induced Photoreaction of o-Nitrobenzyl-Based Ligands under 550 nm Light

Reactivity of atropaldehyde, a felbamate metabolite in human liver tissue in vitro

scientific article published in November 2002

Regio- and Stereoselective Synthesis of 1,1-Diborylalkenes via Brønsted Base-Catalyzed Mixed Diboration of Alkynyl Esters and Amides with BpinBdan

scientific article published on 18 March 2020

Regio- and stereoselective copper-catalyzed β-borylation of allenoates by a preactivated diboron

scientific article

Role of glutathione S-transferases A1-1, M1-1, and P1-1 in the detoxification of 2-phenylpropenal, a reactive felbamate metabolite.

scientific article

Route to Air and Moisture Stable β-Difluoroboryl Acrylamides

scientific article published on 20 September 2019

Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors.

scientific article

Screening of a branched peptide library with HIV-1 TAR RNA.

scientific article

Site-specific incorporation of diamondoids on DNA using click chemistry

scientific article published on 11 January 2012

Small Molecule Mitochondrial Uncouplers and Their Therapeutic Potential

scientific article published on 20 November 2017

Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate

scientific article

Structure and reactivity of a preactivated sp2-sp3 diboron reagent: catalytic regioselective boration of α,β-unsaturated conjugated compounds

scientific article published on 28 April 2011

Structure of a DNA glycosylase searching for lesions

scientific article

Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.

scientific article

Structure-activity relationship studies of the lipophilic tail region of sphingosine kinase 2 inhibitors

scientific article

Structure-activity relationships of furazano[3,4-b]pyrazines as mitochondrial uncouplers.

scientific article

Substrate-Assisted, Transition-Metal-Free Diboration of Alkynamides with Mixed Diboron: Regio- and Stereoselective Access to trans-1,2-Vinyldiboronates

scientific article published on 29 March 2017

Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding

scientific article

Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid

scientific article

Targeting folded RNA: a branched peptide boronic acid that binds to a large surface area of HIV-1 RRE RNA

scientific article

The chemistry, toxicology, and identification in rat and human urine of 4-hydroxy-5-phenyl-1,3-oxazaperhydroin-2-one: a reactive metabolite in felbamate bioactivation.

scientific article

The human cytomegalovirus UL44 C clamp wraps around DNA.

scientific article

The positively charged surface of herpes simplex virus UL42 mediates DNA binding

scientific article

The role of the gap junction perinexus in cardiac conduction: Potential as a novel anti-arrhythmic drug target

scholarly article by Daniel T. Hoagland published in September 2018

Toward targeting RNA structure: branched peptides as cell-permeable ligands to TAR RNA.

scientific article published on 28 October 2011

Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity

scientific article

Transition Metal-Free Trans Hydroboration of Alkynoic Acid Derivatives: Experimental and Theoretical Studies

scientific article published on 20 July 2018

Unexpected copper(II) catalysis: catalytic amine base promoted β-borylation of α,β-unsaturated carbonyl compounds in water

scientific article

[1,2,5]Oxadiazolo[3,4-b]pyrazine-5,6-diamine Derivatives as Mitochondrial Uncouplers for the Potential Treatment of Nonalcoholic Steatohepatitis

scientific article published on 17 February 2020

sp2−sp3Hybridized Mixed Diboron: Synthesis, Characterization, and Copper-Catalyzed β-Boration of α,β-Unsaturated Conjugated Compounds

scientific article published on 01 August 2009

trans-Hydroboration of Propiolamides: Access to Primary and Secondary (E)-β-Borylacrylamides

scientific article published on 08 August 2019

List of works by Webster L Santos

A method for the deprotection of alkylpinacolyl boronate esters

Branched Peptides: Acridine and Boronic Acid Derivatives as Antimicrobial Agents

Branched peptide boronic acids (BPBAs): a novel mode of binding towards RNA.

Brønsted Base-Mediated Regio- and Stereoselective trans-Silaboration of Propargylamides: Access to 1,2-Vinylborasilanes

Catalytic, Transition-Metal-Free Semireduction of Propiolamide Derivatives: Scope and Mechanistic Investigation

Copper(II)-Catalyzed Silyl Conjugate Addition to α,β-Unsaturated Conjugated Compounds: Brønsted Base-Assisted Activation of Si–B Bond in Water

Copper(II)-catalyzed silylation of activated alkynes in water: diastereodivergent access to E- or Z-β-silyl-α,β-unsaturated carbonyl and carboxyl compounds

Copper-boryl mediated organic synthesis

Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors

Diboration of 3-substituted propargylic alcohols using a bimetallic catalyst system: access to (Z)-allyl, vinyldiboronates

Discovery of a Branched Peptide that Recognizes the Rev Response Element (RRE) RNA and Blocks HIV-1 Replication

Discovery of a Small Side Cavity in Sphingosine Kinase 2 that Enhances Inhibitor Potency and Selectivity

Drugging sphingosine kinases.

Effect of alkyl chain length on sphingosine kinase 2 selectivity

Fluorescence lifetime based characterization of active and tunable plasmonic nanostructures

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane

Impact of lithography on the fluorescence dynamics of self-assembled fluorophores

In Silico Characterization of Structural Distinctions between Isoforms of Human and Mouse Sphingosine Kinases for Accelerating Drug Discovery

Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop

Interaction between human serum albumin and the felbamate metabolites 4-Hydroxy-5-phenyl-[1,3]oxazinan-2-one and 2-phenylpropenal

Light-Directed Patchy Particle Fabrication and Assembly from Isotropic Silver Nanoparticles

Lipid phosphate phosphatase-1 expression in cancer cells attenuates tumor growth and metastasis in mice.

Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent.

Mapping targetable sites on human telomerase RNA pseudoknot/template domain using 2'-OMe RNA-interacting polynucleotide (RIPtide) microarrays

Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice

Molecular recognition of a branched peptide with HIV-1 Rev Response Element (RRE) RNA

Multi-photon patterning of photoactive o-nitrobenzyl ligands bound to gold surfaces

N-Terminal peptidic boronic acids selectively inhibit human ClpXP.

Plasmon-Induced Photoreaction of o-Nitrobenzyl-Based Ligands under 550 nm Light

Reactivity of atropaldehyde, a felbamate metabolite in human liver tissue in vitro

Regio- and Stereoselective Synthesis of 1,1-Diborylalkenes via Brønsted Base-Catalyzed Mixed Diboration of Alkynyl Esters and Amides with BpinBdan

Regio- and stereoselective copper-catalyzed β-borylation of allenoates by a preactivated diboron

Role of glutathione S-transferases A1-1, M1-1, and P1-1 in the detoxification of 2-phenylpropenal, a reactive felbamate metabolite.

Route to Air and Moisture Stable β-Difluoroboryl Acrylamides

Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors.

Screening of a branched peptide library with HIV-1 TAR RNA.

Site-specific incorporation of diamondoids on DNA using click chemistry

Small Molecule Mitochondrial Uncouplers and Their Therapeutic Potential

Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate

Structure and reactivity of a preactivated sp2-sp3 diboron reagent: catalytic regioselective boration of α,β-unsaturated conjugated compounds

Structure of a DNA glycosylase searching for lesions

Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.

Structure-activity relationship studies of the lipophilic tail region of sphingosine kinase 2 inhibitors

Structure-activity relationships of furazano[3,4-b]pyrazines as mitochondrial uncouplers.

Substrate-Assisted, Transition-Metal-Free Diboration of Alkynamides with Mixed Diboron: Regio- and Stereoselective Access to trans-1,2-Vinyldiboronates

Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding

Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid

Targeting folded RNA: a branched peptide boronic acid that binds to a large surface area of HIV-1 RRE RNA

The chemistry, toxicology, and identification in rat and human urine of 4-hydroxy-5-phenyl-1,3-oxazaperhydroin-2-one: a reactive metabolite in felbamate bioactivation.

The human cytomegalovirus UL44 C clamp wraps around DNA.

The positively charged surface of herpes simplex virus UL42 mediates DNA binding

The role of the gap junction perinexus in cardiac conduction: Potential as a novel anti-arrhythmic drug target

Toward targeting RNA structure: branched peptides as cell-permeable ligands to TAR RNA.

Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity

Transition Metal-Free Trans Hydroboration of Alkynoic Acid Derivatives: Experimental and Theoretical Studies

Unexpected copper(II) catalysis: catalytic amine base promoted β-borylation of α,β-unsaturated carbonyl compounds in water

[1,2,5]Oxadiazolo[3,4-b]pyrazine-5,6-diamine Derivatives as Mitochondrial Uncouplers for the Potential Treatment of Nonalcoholic Steatohepatitis

sp2−sp3Hybridized Mixed Diboron: Synthesis, Characterization, and Copper-Catalyzed β-Boration of α,β-Unsaturated Conjugated Compounds

trans-Hydroboration of Propiolamides: Access to Primary and Secondary (E)-β-Borylacrylamides