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List of works by Majambu Mbikay

A chimeric proinsulin-CD5 protein expressed in AtT-20 cells is directed to the cell surface via the constitutive pathway

scientific article published on 01 September 1995

A targeted deletion/insertion in the mouse Pcsk1 locus is associated with homozygous embryo preimplantation lethality, mutant allele preferential transmission and heterozygous female susceptibility to dietary fat.

scientific article published in April 2007

Allelic clustering and ancestry-dependent frequencies of rs6232, rs6234, and rs6235 PCSK1 SNPs in a Northern Ontario population sample

scientific article

Altered processing of the neurotensin/neuromedin N precursor in PC2 knock down mice: a biochemical and immunohistochemical study

scientific article published in August 2002

An infant with deletion of the distal long arm of chromosome 15 (q26.1----qter) and loss of insulin-like growth factor 1 receptor gene. ⬇️

scientific article

Assignment of the gene for neuroendocrine protein 7B2 (SGNE1 locus) to mouse chromosome region 2[E3–F3] and to human chromosome region 15q11-q15

article

Association of the rs562556 PCSK9 Gene Polymorphism with Reduced Mortality in Severe Malaria among Malian Children

scientific article published on 16 September 2020

Calcium-induced aggregation of neuroendocrine protein 7B2 in vitro and its modulation by ATP.

scientific article

Characterization of a repressor element in the promoter region of proprotein convertase 2 (PC2) gene

scientific article published in June 2002

Characterization of ostrich (Struthio camelus) beta-microseminoprotein (MSP): identification of homologous sequences in EST databases and analysis of their evolution during speciation

scientific article

Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human

scientific article

Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse

scientific article

Effects of rs6234/rs6235 and rs6232/rs6234/rs6235 PCSK1 single-nucleotide polymorphism clusters on proprotein convertase 1/3 biosynthesis and activity

scientific article published on 24 September 2011

Enzymic characterization in vitro of recombinant proprotein convertase PC4.

scientific article published on October 1999

Ethnic differences in the frequency of the cardioprotective C679X PCSK9 mutation in a West African population

scientific article published in September 2008

Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.

scientific article published in December 2005

Expression of PCSK1 (PC1/3), PCSK2 (PC2) and PCSK3 (furin) in mouse small intestine.

scientific article published on 22 July 2008

Genetic mapping of the gene for SKI-1/S1P protease (locus symbol Mbtps1) to mouse chromosome 8.

scientific article published in April 2002

Immunological identification and sequence characterization of a peptide derived from the processing of neuroendocrine protein 7B2.

scientific article published on December 1991

Impaired fertility in mice deficient for the testicular germ-cell protease PC4

scientific journal article

In vitro elucidation of substrate specificity and bioassay of proprotein convertase 4 using intramolecularly quenched fluorogenic peptides.

scientific article published in June 2004

In vitro regulatory effect of epididymal serpin CRES on protease activity of proprotein convertase PC4/PCSK4.

scientific article

Increased stress-induced analgesia in mice lacking the proneuropeptide convertase PC2.

scientific article

Involvement of matrix metalloproteinases in the adipose conversion of 3T3-L1 preadipocytes.

scientific article published on June 2002

Linkage mapping of the gene for the LIM-homeoprotein LIM3 (locus Lhx3) to mouse Chromosome 2

article

Mice Fed a High-Cholesterol Diet Supplemented with Quercetin-3-Glucoside Show Attenuated Hyperlipidemia and Hyperinsulinemia Associated with Differential Regulation of PCSK9 and LDLR in their Liver and Pancreas.

scientific article published on 3 February 2018

Neuroendocrine secretory protein 7B2: structure, expression and functions

scientific article published in 2001

Novel loss-of-function PCSK9 variant is associated with low plasma LDL cholesterol in a French-Canadian family and with impaired processing and secretion in cell culture

scientific article published on 3 August 2011

Of PCSK9, cholesterol homeostasis and parasitic infections: possible survival benefits of loss-of-function PCSK9 genetic polymorphisms

scientific article published on 14 May 2007

PCSK2-null mice exhibit delayed intestinal motility, reduced refeeding response and altered plasma levels of several regulatory peptides.

scientific article published on 16 November 2010

PCSK4-null sperm display enhanced protein tyrosine phosphorylation and ADAM2 proteolytic processing during in vitro capacitation

scientific journal article

PCSK9 is phosphorylated by a Golgi casein kinase-like kinase ex vivo and circulates as a phosphoprotein in humans

scientific article

PCSK9-deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities.

scientific article published on 16 December 2009

Plasma PCSK9 levels are significantly modified by statins and fibrates in humans

scientific article published on 11 June 2008

Plasma PCSK9 levels correlate with cholesterol in men but not in women

scientific article published on 18 July 2007

Proprotein convertase subtilisin/kexin type 4 in mammalian fertility: a review.

scientific article published on 24 December 2008

Proprotein convertases as therapeutic targets

scientific article published on 01 October 2008

Recombinant proprotein convertase 4 (PC4) from Leishmania tarentolae expression system: purification, biochemical study and inhibitor design.

scientific article published on 25 March 2008

Regulation of 7B2 mRNA translation: dissecting the role of its 5'-untranslated region.

scientific article

Relationship between testosterone, estradiol and circulating PCSK9: Cross-sectional and interventional studies in humans

scientific article published on 07 April 2015

Role of pro-IGF-II processing by proprotein convertase 4 in human placental development

scientific article

Sperm from mice genetically deficient for the PCSK4 proteinase exhibit accelerated capacitation, precocious acrosome reaction, reduced binding to egg zona pellucida, and impaired fertilizing ability

scientific journal article

The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases

scientific article published on 31 August 2005

The enigma of soluble LDLR: could inflammation be the key?

scientific article published on 03 February 2020

The ever-expanding saga of the proprotein convertases and their roles in body homeostasis: emphasis on novel proprotein convertase subtilisin kexin number 9 functions and regulation

scientific article published on 15 January 2018

The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions

scientific article

The precursor to the germ cell-specific PCSK4 proteinase is inefficiently activated in transfected somatic cells: evidence of interaction with the BiP chaperone.

scientific article published on 16 November 2010

The production by alternate splicing of two mRNAs differing by one codon could be an intrinsic property of neuroendocrine protein 7B2 gene expression in man

scientific article

Therapeutic Potential of Moringa oleifera Leaves in Chronic Hyperglycemia and Dyslipidemia: A Review.

scientific article

cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases

scientific article published on April 1996

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