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List of works by Joleen Masschelein

A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics ⬇️

scientific article

A combination of polyunsaturated fatty acid, nonribosomal peptide and polyketide biosynthetic machinery is used to assemble the zeamine antibiotics. ⬇️

scientific article

A conserved motif flags acyl carrier proteins for β-branching in polyketide synthesis

scientific article

A dual transacylation mechanism for polyketide synthase chain release in enacyloxin antibiotic biosynthesis

scientific article published on 23 September 2019

An unusual Burkholderia gladioli double chain-initiating nonribosomal peptide synthetase assembles ‘fungal’ icosalide antibiotics

scientific article published on 25 April 2019

Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights.

scientific article published on 26 June 2017

Artificial intelligence for natural product drug discovery ⬇️

scientific article from 2023

Discovery and Biosynthesis of Gladiolin: A Burkholderia gladioli Antibiotic with Promising Activity against Mycobacterium tuberculosis ⬇️

scientific article published on 22 May 2017

Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics

scientific article published on 11 July 2017

Genome Sequence of Serratia plymuthica RVH1, Isolated from a Raw Vegetable-Processing Line

scientific article published on 06 February 2014

Genomics-driven discovery of a novel glutarimide antibiotic from Burkholderia gladioli reveals an unusual polyketide synthase chain release mechanism ⬇️

scientific article published on 12 September 2020

Isolation and purification of a new kalimantacin/batumin-related polyketide antibiotic and elucidation of its biosynthesis gene cluster

scientific article

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

Pentamycin Biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-Catalyzed Installation of the C-14 Hydroxyl Group ⬇️

scientific article published on 31 May 2019

Structural basis for chain release from the enacyloxin polyketide synthase

scientific article published on 23 September 2019

Systematic analysis of the kalimantacin assembly line NRPS module using an adapted targeted mutagenesis approach.

scientific article published on 15 December 2015

The kalimantacin polyketide antibiotics inhibit fatty acid biosynthesis in Staphylococcus aureus by targeting the enoyl-acyl carrier protein binding site of FabI

scientific article published on 24 March 2020

The kalimantacin/batumin biosynthesis operon encodes a self-resistance isoform of the FabI bacterial target

scientific article published on October 2010

The zeamine antibiotics affect the integrity of bacterial membranes.

scientific article published in December 2014

Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis

scientific article published on 22 August 2016

Total Synthesis of Kalimantacin A

scientific article published on 10 August 2020

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