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List of works by Kam M Hui

A HLA class I cis-regulatory element whose activity can be modulated by hormones

scientific article published on 01 December 1994

A blood-based three-gene signature for the non-invasive detection of early human hepatocellular carcinoma.

scientific article published on 11 December 2013

A microarray study to characterize the molecular mechanism of TIMP-3-mediated tumor rejection.

scientific article published on July 2005

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

scientific article published on 12 January 2017

A paper-based microfluidic electrochemical immunodevice integrated with amplification-by-polymerization for the ultrasensitive multiplexed detection of cancer biomarkers

scientific article

A rapid HLA-DRB1*04 subtyping method using PCR and DNA heteroduplex generators.

scientific article

Acquisition of immunogenicity by AKR leukemic cells following DNA-mediated gene transfer is associated with the reduction of constitutive reactive superoxide radicals

article

An Anti-Human Lutheran Glycoprotein Phage Antibody Inhibits Cell Migration on Laminin-511: Epitope Mapping of the Antibody

scientific article

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.

scientific article published on October 2013

An improved pre-clinical patient-derived liquid xenograft mouse model for acute myeloid leukemia

scientific article published on 6 October 2017

An oncogenic role of Agrin in regulating focal adhesion integrity in hepatocellular carcinoma

scientific article

Ascochlorin Enhances the Sensitivity of Doxorubicin Leading to the Reversal of Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma

scientific article published on 07 October 2016

Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3.

scientific article

Atypical regulators of Wnt/β-catenin signaling as potential therapeutic targets in Hepatocellular Carcinoma.

scientific article

Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepatocellular carcinoma.

scientific article published on 2 May 2014

CCAAT/enhancer binding protein α predicts poorer prognosis and prevents energy starvation-induced cell death in hepatocellular carcinoma

scientific article

CDK1-mediated BCL9 phosphorylation inhibits clathrin to promote mitotic Wnt signalling

scientific article published on 14 September 2018

CIK cells – current status, clinical perspectives and future prospects – the good news ⬇️

scientific article published on April 14, 2012

Carbenoxolone enhances TRAIL-induced apoptosis through the upregulation of death receptor 5 and inhibition of gap junction intercellular communication in human glioma.

scientific article published on 26 March 2013

Characterization of the recognition and functional heterogeneity exhibited by cytokine-induced killer cell subsets against acute myeloid leukaemia target cell

scientific article published on 05 September 2008

Characterization of tumor-specific cytotoxic effector cells with a novel CD3-/Thy-1+ phenotype

scientific article published on 01 November 1995

Clinical and molecular evaluation of warming and tonic herb treatment for sibling patients of a typical kidney-yang deficiency family

scientific article published on 01 January 2006

Cytokine-induced Killer Cells: NK-like T Cells with Cytotolytic Specificity against Leukemia ⬇️

scientific article published on September 1, 2003

DEAD-box helicase DP103 defines metastatic potential of human breast cancers

scientific article

Detection of beta-thalassaemia mutations using DNA heteroduplex generator molecules

scientific article published on 01 July 1995

Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo

scientific article

Differential effect of staphylococcal enterotoxin B upon the induction of tolerance on peripheral CD4+V beta 8+ and CD8+V beta 8+ T cells

scientific article published on 01 October 1994

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells.

scientific article

Dynamics of transgene expression in human glioblastoma cells mediated by herpes simplex virus/adeno-associated virus amplicon vectors.

scientific article published in December 2002

ECT2 regulates the Rho/ERK signalling axis to promote early recurrence in human hepatocellular carcinoma.

scientific article

EDIL3 is a novel regulator of epithelial-mesenchymal transition controlling early recurrence of hepatocellular carcinoma.

scientific article published on 13 May 2015

Emergence of aspirin as a promising chemopreventive and chemotherapeutic agent for liver cancer

scientific article published on 12 October 2017

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

scientific article published on October 2013

Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

scientific article

Engineering an improved cell cycle-regulatable herpes simplex virus type 1 amplicon vector with enhanced transgene expression in proliferating cells yet attenuated activities in resting cells.

scientific article published on March 2007

Eradication of tumor growth via biolistic transformation with allogeneic MHC genes.

scientific article

Establishment of a discriminant mathematical model for diagnosis of deficiency-cold syndrome using gene expression profiling.

scientific article published in October 2006

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers.

scientific article published on March 2015

Gefitinib, cisplatin, and concurrent radiotherapy for locally advanced head and neck cancer: EGFR FISH, protein expression, and mutational status are not predictive biomarkers.

scientific article published on 18 July 2011

Gene regulation profile reveals consistent anticancer properties of progesterone in hormone-independent breast cancer cells transfected with progesterone receptor.

scientific article published on November 2005

Generation of allo-reactive cytotoxic T lymphocytes by particle bombardment-mediated gene transfer

scientific article published on 01 May 1994

Generation of cytokine-induced killer cells from leukaemic samples with in vitro cytotoxicity against autologous and allogeneic leukaemic blasts

scientific article published on 01 January 2002

Generation of potent and specific cellular immune responses via in vivo stimulation of dendritic cells by pNGVL3-hFLex plasmid DNA and immunogenic peptides.

scientific article

Genetic and functional relationship of the HLA-DR and HLA-DQ antigens

scientific article published on 01 January 1985

Genetic polymorphism within HLA-A*02: significant allelic variation revealed in different populations.

scientific article published on April 1995

Glioma-specific and cell cycle-regulated herpes simplex virus type 1 amplicon viral vector.

scientific article published on May 2004

HLA and TAP associations in Chinese systemic lupus erythematosus patients

scientific article published on 01 September 1995

HLA genotyping of colorectal carcinoma in the Chinese population

scientific article published on May 1, 1992

HLA-DR genotyping by restriction fragment length polymorphism analyses

scientific article published on 01 January 1985

HLA-DRB1*01 subtyping by heteroduplex analysis

scientific article published on 01 February 1995

HSV-1 amplicon viral vector-mediated gene transfer to human bone marrow-derived mesenchymal stem cells.

scientific article

Highly specific and ultrasensitive graphene-enhanced electrochemical detection of low-abundance tumor cells using silica nanoparticles coated with antibody-conjugated quantum dots

scientific article published on 27 February 2013

Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis.

scientific article

Human mesenchymal stem cells preferentially migrate toward highly oncogenic human hepatocellular carcinoma cells with activated EpCAM signaling.

scientific article published on 5 May 2017

Identification and characterization of genes involved in the carcinogenesis of human squamous cell cervical carcinoma.

scientific article

Identification and characterization of novel human glioma-specific peptides to potentiate tumor-specific gene delivery.

scientific article published in August 2004

Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.

scientific article published on 8 April 2010

Identification of unique and common low abundance tumour-specific transcripts by suppression subtractive hybridization and oligonucleotide probe array analysis.

scientific article published on 10 March 2008

Induction of alloreactive cytotoxic T lymphocytes by intra-splenic immunization with allogeneic class I Major Histocompatibility Complex DNA and DC-chol cationic liposomes

scientific article published in January 1994

Induction of potent TRAIL-mediated tumoricidal activity by hFLEX/Furin/TRAIL recombinant DNA construct

scientific article published on May 2004

Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model

scientific article published on 20 July 2011

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

scientific article

Insights into the etiology-associated gene regulatory networks in hepatocellular carcinoma from The Cancer Genome Atlas

scientific article published on 19 April 2018

Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme.

scientific article published on 4 December 2017

Locus-specific transcriptional control of HLA genes ⬇️

scientific article published on September 15, 1992

MELK is an oncogenic kinase essential for early hepatocellular carcinoma recurrence

scientific article published on 28 September 2016

Matrix metalloproteinase 1 is necessary for the migration of human bone marrow-derived mesenchymal stem cells toward human glioma.

scientific article published on June 2009

Matrix metalloproteinase-1-mediated mesenchymal stem cell tumor tropism is dependent on crosstalk with stromal derived growth factor 1/C-X-C chemokine receptor 4 axis

scientific article published on 30 June 2014

Mechanism of cancer drug resistance and the involvement of noncoding RNAs

scientific article published on January 2014

Metronomic vinorelbine (oral) in combination with sorafenib in advanced non-small cell lung cancer.

scientific article published on 13 April 2015

MiR-214 targets β-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma.

scientific article

MicroRNA-216a/217-Induced Epithelial-Mesenchymal Transition Targets Pten and SMAD7 to Promote Drug Resistance and Recurrence of Liver Cancer ⬇️

scientific article published on June 25, 2013

MicroRNAs involved in regulating epithelial-mesenchymal transition and cancer stem cells as molecular targets for cancer therapeutics.

scientific article published on 14 September 2012

Modifiable chromatophore proteins in photosynthetic bacteria ⬇️

scientific article published on April 1, 1979

Modulation of iron-regulatory genes in human hepatocellular carcinoma and its physiological consequences.

scientific article published on 23 March 2009

Molecular targets and anti-cancer potential of escin

scientific article published on 20 February 2018

N'-Alkylaminosulfonyl Analogues of 6-Fluorobenzylideneindolinones with Desirable Physicochemical Profiles and Potent Growth Inhibitory Activities on Hepatocellular Carcinoma.

scientific article

Nanosized bioceramic particles could function as efficient gene delivery vehicles with target specificity for the spleen.

scientific article

Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model.

scientific article published on 9 December 2015

Optimal purification method for Herpes-based viral vectors that confers minimal cytotoxicity for systemic route of vector administration.

scientific article

Organelle Specific O-Glycosylation Drives MMP14 Activation, Tumor Growth, and Metastasis.

scientific article published in November 2017

Paper-based microfluidic electrochemical immunodevice integrated with nanobioprobes onto graphene film for ultrasensitive multiplexed detection of cancer biomarkers

scientific article published on 27 August 2013

Paracrine factors of human fetal MSCs inhibit liver cancer growth through reduced activation of IGF-1R/PI3K/Akt signaling

scientific article

Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA–liposome complexes ⬇️

scientific article published on August 1, 1997

Phenotypic and functional alterations of Vgamma2Vdelta2 T cell subsets in patients with active nasopharyngeal carcinoma.

scientific article

Preclinical evaluation of transcriptional targeting strategy for human hepatocellular carcinoma in an orthotopic xenograft mouse model.

scientific article published on 29 May 2013

Re-expression of major histocompatibility complex (MHC) class I molecules on malignant tumor cells and its effect on host-tumor interaction.

scientific article

Redox-Active Mn Porphyrin-based Potent SOD Mimic, MnTnBuOE-2-PyP(5+), Enhances Carbenoxolone-Mediated TRAIL-Induced Apoptosis in Glioblastoma Multiforme.

scientific article published on 10 October 2015

Rejection of transplantable AKR leukaemia cells following MHC DNA-mediated cell transformation ⬇️

scientific article published on October 25, 1984

Single-layer MoS2 nanosheet grafted upconversion nanoparticles for near-infrared fluorescence imaging-guided deep tissue cancer phototherapy.

scientific article published on April 2016

Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivo

scientific article published on 03 December 2010

Synthesis of a novel series of cationic lipids that can act as efficient gene delivery vehicles through systematic heterocyclic substitution of cholesterol derivatives.

scientific article

Systemically delivered measles virus-infected mesenchymal stem cells can evade host immunity to inhibit liver cancer growth.

scientific article

Targeting human glioma cells using HSV-1 amplicon peptide display vector.

scientific article published on 8 October 2009

Targeting transcription factor STAT3 for cancer prevention and therapy.

scientific article

Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression

scientific article published on 19 September 2016

The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma

scientific article published on 16 March 2022

The innovative evolution of cancer gene and cellular therapies ⬇️

scientific article published on February 1, 2013

The microtubule-associated protein PRC1 promotes early recurrence of hepatocellular carcinoma in association with the Wnt/β-catenin signalling pathway.

scientific article published on 03 March 2016

The nucleotide sequence of the H-2K gene of C3Hf/HeN mice

scientific article published on 01 January 1988

The over-expression of survivin enhances the chemotherapeutic efficacy of YM155 in human hepatocellular carcinoma.

scientific article published on March 2015

The relevance of oncogenes as prognostic markers in cervical cancer

scientific article published on 01 September 2002

The tumor suppressor function of LECT2 in human hepatocellular carcinoma makes it a potential therapeutic target.

scientific article published on 11 March 2011

Transcriptional down-regulation of IGFBP-3 in human hepatocellular carcinoma cells is mediated by the binding of TIA-1 to its AT-rich element in the 3'-untranslated region.

scientific article published on 6 July 2010

Transgenic Animals and the Study of the Immune System

scientific article published on January 1, 1993

Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma.

scientific article

Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice ⬇️

scientific article published on April 5, 2011

Ursolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathways

scientific article

Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model.

scientific article

p16INK4A-silencing augments DNA damage-induced apoptosis in cervical cancer cells.

scientific article published on 19 March 2007

pH-Sensitive Pt Nanocluster Assembly Overcomes Cisplatin Resistance and Heterogeneous Stemness of Hepatocellular Carcinoma

scientific article published on 17 October 2016

pH-sensitive nanoformulated triptolide as a targeted therapeutic strategy for hepatocellular carcinoma.

scientific article

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