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List of works by Joseph R. Hume

"Creep currents" in single frog atrial cells may be generated by electrogenic Na/Ca exchange

scientific article

A novel anionic inward rectifier in native cardiac myocytes

scientific article published on 01 March 2000

A plethora of cardiac chloride conductances: molecular diversity or a related gene family

scientific article published on April 1995

A serine residue in ClC-3 links phosphorylation-dephosphorylation to chloride channel regulation by cell volume

scientific article

A time- and voltage-dependent K+ current in single cardiac cells from bullfrog atrium

scientific article

A whole-cell patch clamp technique which minimizes cell dialysis

scientific article published in March 1988

ATPo but not cAMPi activates a chloride conductance in mouse ventricular myocytes

scientific article published on 01 March 1995

Action potentials and membrane currents of isolated single smooth muscle cells of cat and rabbit colon

scientific article

Actions of phencyclidine on the action potential and membrane currents of single guinea-pig myocytes.

scientific article

Active and passive electrical properties of single bullfrog atrial cells

scientific article

Altered properties of volume-sensitive osmolyte and anion channels (VSOACs) and membrane protein expression in cardiac and smooth muscle myocytes from Clcn3-/- mice

scientific article published on 12 March 2004

Alternative splicing of CFTR Cl- channels in heart ⬇️

scientific article published on 01 June 1993

An intrinsic potential-dependent inactivation mechanism associated with calcium channels in guinea-pig myocytes

scientific article published in August 1987

Anchoring protein is required for cAMP-dependent stimulation of L-type Ca(2+) channels in rabbit portal vein

scientific article published on 01 October 1999

Anion and cation modulation of the guinea-pig ventricular action potential during beta-adrenoceptor stimulation

scientific article published on 01 June 1993

Anion transport in heart

scientific article (publication date: 2000)

Autonomic regulation of a chloride current in heart

scientific article published on 01 May 1989

Autonomic regulation of delayed rectifier K+ current in mammalian heart involves G proteins

scientific article published on 01 September 1989

Block by 4-aminopyridine of a Kv1.2 delayed rectifier K+ current expressed in Xenopus oocytes

scientific article published in December 1994

CFTR chloride channels in human and simian heart

scientific article

CLC-3 chloride channels in the pulmonary vasculature

scientific article published on January 2010

Caffeine inhibits InsP3 responses and capacitative calcium entry in canine pulmonary arterial smooth muscle cells ⬇️

scientific article

Calcium channel antagonist properties of Bay K 8644 in single guinea pig ventricular cells

scientific article published in January 1988

Cardiac-specific overexpression of the human short CLC-3 chloride channel isoform in mice

scientific article

Cardiac-specific, inducible ClC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice

scientific article

Cell culture alters Ca2+ entry pathways activated by store-depletion or hypoxia in canine pulmonary arterial smooth muscle cells

scientific article published on 31 October 2007

Chloride conductance pathways in heart

scientific article published on September 1991

Chloride current in mammalian cardiac myocytes. Novel mechanism for autonomic regulation of action potential duration and resting membrane potential

scientific article

ClC-3 chloride channel is upregulated by hypertrophy and inflammation in rat and canine pulmonary artery

scientific article

ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytes

scientific article

Cloning and characterization of a Kv1.5 delayed rectifier K+ channel from vascular and visceral smooth muscles

scientific article published in November 1994

Cloning and expression of a Kv1.2 class delayed rectifier K+ channel from canine colonic smooth muscle

scientific article published on October 1993

Comparative capacitative calcium entry mechanisms in canine pulmonary and renal arterial smooth muscle cells

scientific article published in September 2002

Comparative interactions of organic Ca++ channel antagonists with myocardial Ca++ and K+ channels

scientific article published on 01 July 1985

Comparison of K+ channels in mammalian atrial and ventricular myocytes

scientific article published on 01 January 1990

Component of whole cell Ca current due to electrogenic Na-Ca-exchange in cardiac myocytes

scientific article published on 01 March 1987

Cromakalim and lemakalim activate Ca(2+)-dependent K+ channels in canine colon

scientific article published on 01 May 1992

Cystic fibrosis gene encodes a cAMP-dependent chloride channel in heart

scientific article published on June 1996

D 600 block of L-type Ca2+ channel in vascular smooth muscle cells: comparison with permanently charged derivative, D 890.

scientific article published on October 1989

Differential expression and alternative splicing of TRP channel genes in smooth muscles

scientific article published on 01 May 2001

Dihydropyridine-sensitive calcium channels expressed in canine colonic smooth muscle cells ⬇️

scientific article published on March 1, 1993

Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction

scientific article published on April 1, 1992

Do catecholamines directly modulate the delayed plateau potassium current in frog atrium?

scientific article published on 01 August 1985

Effect of cromakalim and lemakalim on slow waves and membrane currents in colonic smooth muscle

scientific article published on 01 February 1991

Effects of autonomic neurotransmitters on automaticity in ventricular myocardium

scientific article published on January 1, 1977

Electrophysiological mechanisms of minoxidil sulfate-induced vasodilation of rabbit portal vein

scientific article published on 01 October 1989

Evidence that outwardly rectifying Cl- channels underlie volume-regulated Cl- currents in heart

scientific article published on January 1997

Expression of cystic fibrosis transmembrane regulator Cl- channels in heart

scientific article published on October 1, 1992

Functional and molecular expression of volume‐regulated chloride channels in canine vascular smooth muscle cells ⬇️

scientific article published on March 15, 1998

Functional and molecular identification of a novel chloride conductance in canine colonic smooth muscle ⬇️

scientific article published on 01 October 1998

Functional characterization of novel alternatively spliced ClC-2 chloride channel variants in the heart

scientific article published on 9 May 2005

Functional effects of novel anti-ClC-3 antibodies on native volume-sensitive osmolyte and anion channels in cardiac and smooth muscle cells

scientific article published on 19 June 2003

Functional inhibition of native volume-sensitive outwardly rectifying anion channels in muscle cells and Xenopus oocytes by anti-ClC-3 antibody

scientific article published on March 2001

Functional role of amino terminus in ClC-3 chloride channel regulation by phosphorylation and cell volume

scientific article published on May 2006

Functional role of anion channels in cardiac diseases

scientific article

Heterogeneity of calcium stores and elementary release events in canine pulmonary arterial smooth muscle cells

scientific article

Hypotonic activation of short ClC3 isoform is modulated by direct interaction between its cytosolic C-terminal tail and subcortical actin filaments

scientific article published on 17 April 2007

Hypotonic activation of volume-sensitive outwardly rectifying anion channels (VSOACs) requires coordinated remodeling of subcortical and perinuclear actin filaments

scientific article published in November 2005

Hypotonic activation of volume-sensitive outwardly rectifying chloride channels in cultured PASMCs is modulated by SGK.

scientific article published on 15 April 2004

Inactivation of calcium current in bull-frog atrial myocytes

scientific article

Inhibition of ryanodine receptors by 4-(2-aminopropyl)-3,5-dichloro-N,N-dimethylaniline (FLA 365) in canine pulmonary arterial smooth muscle cells

scientific article

Inhibitory effects of glibenclamide on cystic fibrosis transmembrane regulator, swelling-activated, and Ca(2+)-activated Cl- channels in mammalian cardiac myocytes

scientific article published in July 1997

Interactions of organic calcium channel antagonists with calcium channels in single frog atrial cells

scientific article

Intracellular Na+ modulates the cAMP-dependent regulation of ion channels in the heart

scientific article published on August 1991

Intracellular cyclic AMP inhibits native and recombinant volume-regulated chloride channels from mammalian heart

scientific article published on March 2000

Intracellular divalent cations block smooth muscle K+ channels ⬇️

scientific article published on July 1, 1993

Ionic basis for spontaneous depolarizations in isolated smooth muscle cells of canine colon

scientific article published in September 1992

Ionic basis of the different action potential configurations of single guinea-pig atrial and ventricular myocytes

scientific article published in November 1985

Ionic currents in single isolated bullfrog atrial cells

scientific article

Ionic currents in single smooth muscle cells of the canine renal artery

scientific article published on October 1, 1992

Isoproterenol activates a chloride current, not the transient outward current, in rabbit ventricular myocytes

scientific article published in December 1989

Low osmolarity transforms ventricular fibrillation from complex to highly organized, with a dominant high-frequency source

scientific article published on 8 July 2006

Lysophosphatidylcholine triggers intracellular calcium release and activation of non-selective cation channels in renal arterial smooth muscle cells

scientific article published on 01 February 2000

Macroscopic K+ currents in single smooth muscle cells of the rabbit portal vein.

scientific article

Membrane electrical properties of vesicular Na-Ca exchange inhibitors in single atrial myocytes

scientific article

Mobilization of sarcoplasmic reticulum stores by hypoxia leads to consequent activation of capacitative Ca2+ entry in isolated canine pulmonary arterial smooth muscle cells

scientific article published on 21 December 2004

Modulation of Ca 2+ Channels by Cyclic Nucleotide Cross Activation of Opposing Protein Kinases in Rabbit Portal Vein ⬇️

scientific article published on March 23, 1998

Modulation of K+ and Ca2+ channels by histamine H1-receptor stimulation in rabbit coronary artery cells.

scientific article

Molecular distribution of volume-regulated chloride channels (ClC-2 and ClC-3) in cardiac tissues

scientific article published on 01 November 2000

Molecular identification of a volume-regulated chloride channel ⬇️

scientific article published on November 27, 1997

Molecular mechanisms of regulation of fast-inactivating voltage-dependent transient outward K+ current in mouse heart by cell volume changes

scientific article

Molecular physiology of CFTR Cl- channels in heart.

scientific article published in January 1994

NO and the regulation of VSOACs

scientific article published on 01 October 2000

Orai1 interacts with STIM1 and mediates capacitative Ca2+ entry in mouse pulmonary arterial smooth muscle cells ⬇️

scientific article published on August 25, 2010

P2Y purinergic receptor regulation of CFTR chloride channels in mouse cardiac myocytes

scientific article published on 20 February 2004

Paradoxical positive inotropic effect of K+ in the rat heart

scientific article published in May 1987

Permeability of time-dependent K+ channel in guinea pig ventricular myocytes to Cs+, Na+, NH4+, and Rb+.

scientific article

Physiological role of endogenous amines in the modulation of ventricular automaticity in the guinea-pig

scientific article published on December 1980

Presynaptic and postsynaptic actions of cadmium in cardiac muscle

scientific article published on 01 October 1983

Prominent role of intracellular Ca2+ release in hypoxic vasoconstriction of canine pulmonary artery ⬇️

scientific article published on September 1, 1997

Properties of "creep currents" in single frog atrial cells

scientific article

Purinoceptor-coupled Cl- channels in mouse heart: a novel, alternative pathway for CFTR regulation

Re-examination of Na+-dependent regulation of cAMP-dependent Cl- currents in the heart

scientific article published on 01 March 1997

Regulation of Ca2+ channels by cAMP and cGMP in vascular smooth muscle cells

scientific article published on 01 December 1993

Regulation of L-type Ca2+ channels in rabbit portal vein by G protein alphas and betagamma subunits

scientific article published on 01 May 1999

Regulation of cardiac and smooth muscle Ca(2+) channels (Ca(V)1.2a,b) by protein kinases

scientific article published in December 2001

Regulation of recombinant cardiac cystic fibrosis transmembrane conductance regulator chloride channels by protein kinase C.

scientific article

Regulation of volume-sensitive outwardly rectifying anion channels in pulmonary arterial smooth muscle cells by PKC.

scientific article published on 7 August 2002

Relationship between calcium current and cytosolic calcium in canine gastric smooth muscle cells

scientific article published on May 1991

Release of calcium from guinea pig cardiac sarcoplasmic reticulum induced by sodium-calcium exchange

scientific article

Reversal potential of the calcium current in bull-frog atrial myocytes

scientific article published in September 1988

Role of InsP3 and ryanodine receptors in the activation of capacitative Ca2+ entry by store depletion or hypoxia in canine pulmonary arterial smooth muscle cells

scientific article published on 25 June 2007

Role of basal extracellular Ca2+ entry during 5-HT-induced vasoconstriction of canine pulmonary arteries

scientific article

Role of reverse-mode Na(+)-Ca2+ exchange in excitation-contraction coupling in the heart.

scientific article

Sodium current depression by lidocaine and quinidine in isolated ventricular cells ⬇️

scientific article published on May 28, 1981

Sodium current-induced release of calcium from cardiac sarcoplasmic reticulum

scientific article

TRPC1 and Orai1 interact with STIM1 and mediate capacitative Ca2+ entry caused by acute hypoxia in mouse pulmonary arterial smooth muscle cells ⬇️

scientific article published on October 3, 2012

TRPC1 and STIM1 mediate capacitative Ca2+ entry in mouse pulmonary arterial smooth muscle cells

scientific article

The contribution of TRPC1 and STIM1 to capacitative Ca(2+) entry in pulmonary artery

scientific article published on January 2010

The effects of alpha- and beta-adrenergic agonists upon depolarization induced ventricular automaticity

scientific article published on January 1, 1978

Unitary Cl- channels activated by cytoplasmic Ca2+ in canine ventricular myocytes

scientific article published in May 1996

Unitary chloride channels activated by protein kinase C in guinea pig ventricular myocytes.

scientific article

Voltage clamp comparison of the organic calcium channel blockers D-600 and nisoldipine

scientific article published on 01 January 1984

Voltage-dependent action of tetrodotoxin in mammalian cardiac myocytes

scientific article published in August 1986

[Ca2+]i inhibition of K+ channels in canine pulmonary artery. Novel mechanism for hypoxia-induced membrane depolarization

scientific article published on 01 July 1995

[Ca2+]i inhibition of K+ channels in canine renal artery. Novel mechanism for agonist-induced membrane depolarization

scientific article published on 01 July 1995

beta-Adrenergic receptor stimulation of L-type Ca2+ channels in rabbit portal vein myocytes involves both alphas and betagamma G protein subunits

scientific article

pH regulation of voltage-dependent K+ channels in canine pulmonary arterial smooth muscle cells

scientific article published on 01 April 1997

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