List of works - Montserrat Marí

A Nutraceutical Rich in Docosahexaenoic Acid Improves Portal Hypertension in a Preclinical Model of Advanced Chronic Liver Disease

scientific article published on 03 October 2019

ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.

scientific article published on 23 May 2013

Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesis

scientific article

Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis

scientific article published on March 2004

Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1.

scientific article published in April 2002

Alcohol, signaling, and ECM turnover.

scientific article published on 23 October 2009

Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer

scientific article

Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma.

scientific article published on 30 March 2018

Bone morphogenetic protein-9/activin-like kinase 1 axis a new target for hepatic regeneration and fibrosis treatment in liver injury

scientific article published in December 2017

Bradykinin attenuates hepatocellular damage and fibrosis in rats with chronic liver injury

scientific article published on 26 September 2007

CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase.

scientific article

CYP2E1-dependent toxicity and up-regulation of antioxidant genes.

scientific article

Cathepsin B overexpression due to acid sphingomyelinase ablation promotes liver fibrosis in Niemann-Pick disease

scientific article published on 18 November 2011

Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential

scientific article published on April 2009

Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility.

scientific article published on 14 April 2011

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

scientific article

Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion

scientific article published on 04 June 2018

Cholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidity

scientific journal article

Critical role of acidic sphingomyelinase in murine hepatic ischemia-reperfusion injury.

scientific article

Critical role of mitochondrial glutathione in the survival of hepatocytes during hypoxia

scientific article

Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis

scientific article published on July 2011

Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation.

scientific article

Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

scientific article

Defective TNF-α–mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

Differential Role of Cathepsins S and B In Hepatic APC-Mediated NKT Cell Activation and Cytokine Secretion.

scientific article

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

scientific article published in Journal of Biological Chemistry

Divergent role of ceramide generated by exogenous sphingomyelinases on NF-kappa B activation and apoptosis in human colon HT-29 cells.

scientific article published in August 2002

Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation

scientific article

Genetic and clinical data reinforce the role of GAS6 and TAM receptors in liver fibrosis.

scientific article published on 25 January 2016

Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans

scientific article published in March 2010

Glycosphingolipids and mitochondria: role in apoptosis and disease.

scientific article published in January 2004

Growth arrest-specific protein 6 is hepatoprotective against murine ischemia/reperfusion injury.

scientific article

Hepatocarcinogenesis and ceramide/cholesterol metabolism

scientific article published on May 2012

Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development

scientific article

Induction of catalase, alpha, and microsomal glutathione S-transferase in CYP2E1 overexpressing HepG2 cells and protection against short-term oxidative stress.

scientific article

Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense

scientific article published on 01 October 2020

Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-kappaB activation.

scientific article

Metabolic therapy: lessons from liver diseases.

scientific article published on December 2011

Mitochondrial Glutathione: Recent Insights and Role in Disease

scientific article published on 24 September 2020

Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress.

scientific article

Mitochondrial cholesterol: a connection between caveolin, metabolism, and disease

scientific article published on 25 August 2011

Mitochondrial dysfunction in non-alcoholic fatty liver disease and insulin resistance: cause or consequence?

scientific article published on 04 October 2013

Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

scientific article published on September 2006

Mitochondrial glutathione, a key survival antioxidant

scientific article

Mitochondrial glutathione: features, regulation and role in disease

scientific article

Mitochondrial permeability transition induced by reactive oxygen species is independent of cholesterol-regulated membrane fluidity

scientific article published in February 2004

Reactive oxygen species mediate liver injury through parenchymal nuclear factor-kappaB inactivation in prolonged ischemia/reperfusion

scientific article published on 06 April 2009

Recent Insights into the Mitochondrial Role in Autophagy and Its Regulation by Oxidative Stress

scientific article published on 04 November 2019

Redox control of liver function in health and disease

scientific article

Relevance of SIRT1-NF-κB Axis as Therapeutic Target to Ameliorate Inflammation in Liver Disease

scientific article published on 29 May 2020

Reply

Role of Vitamin K-Dependent Factors Protein S and GAS6 and TAM Receptors in SARS-CoV-2 Infection and COVID-19-Associated Immunothrombosis

scientific article published on 28 September 2020

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

scientific article published on 01 December 1998

Sphingolipid signalling and liver diseases

scientific article published on May 2007

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma

scientific article published on 22 January 2016

Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase.

scientific article published on November 1997

List of works by Montserrat Marí

A Nutraceutical Rich in Docosahexaenoic Acid Improves Portal Hypertension in a Preclinical Model of Advanced Chronic Liver Disease

ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.

Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesis

Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis

Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1.

Alcohol, signaling, and ECM turnover.

Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer

Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma.

Bone morphogenetic protein-9/activin-like kinase 1 axis a new target for hepatic regeneration and fibrosis treatment in liver injury

Bradykinin attenuates hepatocellular damage and fibrosis in rats with chronic liver injury

CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase.

CYP2E1-dependent toxicity and up-regulation of antioxidant genes.

Cathepsin B overexpression due to acid sphingomyelinase ablation promotes liver fibrosis in Niemann-Pick disease

Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential

Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility.

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion

Cholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidity

Critical role of acidic sphingomyelinase in murine hepatic ischemia-reperfusion injury.

Critical role of mitochondrial glutathione in the survival of hepatocytes during hypoxia

Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis

Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation.

Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

Defective TNF-α–mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

Differential Role of Cathepsins S and B In Hepatic APC-Mediated NKT Cell Activation and Cytokine Secretion.

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

Divergent role of ceramide generated by exogenous sphingomyelinases on NF-kappa B activation and apoptosis in human colon HT-29 cells.

Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation

Genetic and clinical data reinforce the role of GAS6 and TAM receptors in liver fibrosis.

Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans

Glycosphingolipids and mitochondria: role in apoptosis and disease.

Growth arrest-specific protein 6 is hepatoprotective against murine ischemia/reperfusion injury.

Hepatocarcinogenesis and ceramide/cholesterol metabolism

Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development

Induction of catalase, alpha, and microsomal glutathione S-transferase in CYP2E1 overexpressing HepG2 cells and protection against short-term oxidative stress.

Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense

Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-kappaB activation.

Metabolic therapy: lessons from liver diseases.

Mitochondrial Glutathione: Recent Insights and Role in Disease

Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress.

Mitochondrial cholesterol: a connection between caveolin, metabolism, and disease

Mitochondrial dysfunction in non-alcoholic fatty liver disease and insulin resistance: cause or consequence?

Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

Mitochondrial glutathione, a key survival antioxidant

Mitochondrial glutathione: features, regulation and role in disease

Mitochondrial permeability transition induced by reactive oxygen species is independent of cholesterol-regulated membrane fluidity

Reactive oxygen species mediate liver injury through parenchymal nuclear factor-kappaB inactivation in prolonged ischemia/reperfusion

Recent Insights into the Mitochondrial Role in Autophagy and Its Regulation by Oxidative Stress

Redox control of liver function in health and disease

Relevance of SIRT1-NF-κB Axis as Therapeutic Target to Ameliorate Inflammation in Liver Disease

Reply

Role of Vitamin K-Dependent Factors Protein S and GAS6 and TAM Receptors in SARS-CoV-2 Infection and COVID-19-Associated Immunothrombosis

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

Sphingolipid signalling and liver diseases

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma

Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase.