List of works - Margaret de Castro

A Single Nucleotide Variant in the Promoter Region of 17β-HSD Type 5 Gene Influences External Genitalia Virilization in Females with 21-Hydroxylase Deficiency.

scientific article

A novel ADIPOQ mutation (p.M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome

scientific article published on 16 January 2014

A novel homozygous splice acceptor site mutation of KISS1R in two siblings with normosmic isolated hypogonadotropic hypogonadism

scientific article published on 06 April 2010

A rational, non-radioactive strategy for the molecular diagnosis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

scientific article published on 06 April 2013

AIP expression in sporadic somatotropinomas is a predictor of the response to octreotide LAR therapy independent of SSTR2 expression

scientific article published on 24 May 2012

Absence of TERT promoter mutations in pituitary adenomas.

scientific article

Adiponectin: serum levels, promoter polymorphism, and associations with birth size and cardiometabolic outcome in young adults born large for gestational age.

scientific article published on 19 October 2009

Altered functioning of the HPA axis in depressed postpartum women

scientific article published on 31 December 2015

Central precocious puberty that appears to be sporadic caused by paternally inherited mutations in the imprinted gene makorin ring finger 3.

scientific article

Clinical assessment and molecular analysis of GnRHR and KAL1 genes in males with idiopathic hypogonadotrophic hypogonadism.

scientific article published in February 2007

Clinical features and genetic analysis of four Brazilian kindreds with resistance to thyroid hormone

scientific article published on 04 July 2007

Comments to "a rational, non-radioactive strategy for the molecular diagnosis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency".

scientific article published on 4 October 2013

Corticotrophin-releasing factor mediates hypophagia after adrenalectomy, increasing meal-related satiety responses ⬇️

scientific article published on August 3, 2010

Dopamine receptor subtype 2 expression profile in nonfunctioning pituitary adenomas and in vivo response to cabergoline therapy.

scientific article published on 8 January 2015

Expression of hypothalamic neuropeptides and the desensitization of pituitary-adrenal axis and hypophagia in the endotoxin tolerance

scientific journal article

Expression profile of apoptosis-related genes in childhood adrenocortical tumors: low level of expression of BCL2 and TNF genes suggests a poor prognosis

scientific article published on 22 May 2012

Ghrelin and PYY(3-36) in gastrectomized and vagotomized patients: relations with appetite, energy intake and resting energy expenditure.

scientific article published on 19 May 2010

Glucocorticoid modulation of atrial natriuretic peptide, oxytocin, vasopressin and Fos expression in response to osmotic, angiotensinergic and cholinergic stimulation.

scientific article

Glucocorticoid resistance in dialysis patients reduces long-term graft survival after kidney transplantation

scientific article published on 16 April 2014

Glucocorticoid sensitivity and proinflammatory cytokines pattern in pemphigus.

scientific article

HPA axis dysregulation, NR3C1 polymorphisms and glucocorticoid receptor isoforms imbalance in metabolic syndrome.

scientific article

Heterogeneity in the molecular basis of ACTH resistance syndrome.

scientific article

Hypothalamic-pituitary axis and peripheral tissue responses to TRH stimulation and liothyronine suppression tests in normal subjects evaluated by current methods.

scientific article published in April 2008

Inflammation, myocardial dysfunction, and mortality in children with septic shock: an observational study

scientific article published on 4 October 2013

Letter to the Editor: Comments on "LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal" by Shaikh L.H., et al

scientific article published on 01 December 2015

Long-term treatment of familial male-limited precocious puberty (testotoxicosis) with cyproterone acetate or ketoconazole.

scientific article

Loss-of-Function Mutations in the Genes Encoding Prokineticin-2 or Prokineticin Receptor-2 Cause Autosomal Recessive Kallmann Syndrome

article

Low expression of HLA-DRA, HLA-DPA1, and HLA-DPB1 is associated with poor prognosis in pediatric adrenocortical tumors (ACT)

scientific article published on 23 August 2014

P27/CDKN1B Translational Regulators in Pituitary Tumorigenesis.

scientific article published on 7 November 2016

Peripheral parameters of thyroid hormone action in resistance to thyroid hormone syndrome: a focus on mineral metabolism.

scientific article published in July 2009

Phenotypic diversity and glucocorticoid sensitivity in patients with familial partial lipodystrophy type 2

scientific article published on 15 April 2019

Postnatal growth and cardiometabolic profile in young adults born large for gestational age

scientific article published on 01 September 2011

Postnatal ontogeny of the circadian expression of the adrenal clock genes and corticosterone rhythm in male rats.

scientific article

Prostaglandin mediates endotoxaemia-induced hypophagia by activation of pro-opiomelanocortin and corticotrophin-releasing factor neurons in rats.

scientific article

Quantitative magnetic resonance imaging evaluation of the olfactory system in Kallmann syndrome: correlation with a clinical smell test.

scientific article published on 21 May 2011

Regulation of aryl hydrocarbon receptor interacting protein (AIP) protein expression by MiR-34a in sporadic somatotropinomas

scientific article

Reply to the editor

Sonic Hedgehog mutations are not a common cause of congenital hypopituitarism in the absence of complex midline cerebral defects

scientific article published on 22 September 2014

Sonic hedgehog signaling is active in human adrenal cortex development and deregulated in adrenocortical tumors

scientific article published on 8 April 2014

Spindle assembly checkpoint gene expression in childhood adrenocortical tumors (ACT): Overexpression of Aurora kinases A and B is associated with a poor prognosis.

scientific article published on 20 June 2013

TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood

scientific article

Telomere length and telomerase expression in pituitary tumors.

scientific article

The functioning of the hypothalamic-pituitary-adrenal (HPA) axis in postpartum depressive states: a systematic review

scientific article published on 06 July 2017

Transcriptome Analysis Showed a Differential Signature between Invasive and Non-invasive Corticotrophinomas

scientific article published on 22 March 2017

Unraveling the expression of the oncogene YAP1, a Wnt/beta-catenin target, in adrenocortical tumors and its association with poor outcome in pediatric patients.

scientific article published on October 2016

List of works by Margaret de Castro

A Single Nucleotide Variant in the Promoter Region of 17β-HSD Type 5 Gene Influences External Genitalia Virilization in Females with 21-Hydroxylase Deficiency.

A novel ADIPOQ mutation (p.M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome

A novel homozygous splice acceptor site mutation of KISS1R in two siblings with normosmic isolated hypogonadotropic hypogonadism

A rational, non-radioactive strategy for the molecular diagnosis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

AIP expression in sporadic somatotropinomas is a predictor of the response to octreotide LAR therapy independent of SSTR2 expression

Absence of TERT promoter mutations in pituitary adenomas.

Adiponectin: serum levels, promoter polymorphism, and associations with birth size and cardiometabolic outcome in young adults born large for gestational age.

Altered functioning of the HPA axis in depressed postpartum women

Central precocious puberty that appears to be sporadic caused by paternally inherited mutations in the imprinted gene makorin ring finger 3.

Clinical assessment and molecular analysis of GnRHR and KAL1 genes in males with idiopathic hypogonadotrophic hypogonadism.

Clinical features and genetic analysis of four Brazilian kindreds with resistance to thyroid hormone

Comments to "a rational, non-radioactive strategy for the molecular diagnosis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency".

Corticotrophin-releasing factor mediates hypophagia after adrenalectomy, increasing meal-related satiety responses ⬇️

Dopamine receptor subtype 2 expression profile in nonfunctioning pituitary adenomas and in vivo response to cabergoline therapy.

Expression of hypothalamic neuropeptides and the desensitization of pituitary-adrenal axis and hypophagia in the endotoxin tolerance

Expression profile of apoptosis-related genes in childhood adrenocortical tumors: low level of expression of BCL2 and TNF genes suggests a poor prognosis

Ghrelin and PYY(3-36) in gastrectomized and vagotomized patients: relations with appetite, energy intake and resting energy expenditure.

Glucocorticoid modulation of atrial natriuretic peptide, oxytocin, vasopressin and Fos expression in response to osmotic, angiotensinergic and cholinergic stimulation.

Glucocorticoid resistance in dialysis patients reduces long-term graft survival after kidney transplantation

Glucocorticoid sensitivity and proinflammatory cytokines pattern in pemphigus.

HPA axis dysregulation, NR3C1 polymorphisms and glucocorticoid receptor isoforms imbalance in metabolic syndrome.

Heterogeneity in the molecular basis of ACTH resistance syndrome.

Hypothalamic-pituitary axis and peripheral tissue responses to TRH stimulation and liothyronine suppression tests in normal subjects evaluated by current methods.

Inflammation, myocardial dysfunction, and mortality in children with septic shock: an observational study

Letter to the Editor: Comments on "LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal" by Shaikh L.H., et al

Long-term treatment of familial male-limited precocious puberty (testotoxicosis) with cyproterone acetate or ketoconazole.

Loss-of-Function Mutations in the Genes Encoding Prokineticin-2 or Prokineticin Receptor-2 Cause Autosomal Recessive Kallmann Syndrome

Low expression of HLA-DRA, HLA-DPA1, and HLA-DPB1 is associated with poor prognosis in pediatric adrenocortical tumors (ACT)

P27/CDKN1B Translational Regulators in Pituitary Tumorigenesis.

Peripheral parameters of thyroid hormone action in resistance to thyroid hormone syndrome: a focus on mineral metabolism.

Phenotypic diversity and glucocorticoid sensitivity in patients with familial partial lipodystrophy type 2

Postnatal growth and cardiometabolic profile in young adults born large for gestational age

Postnatal ontogeny of the circadian expression of the adrenal clock genes and corticosterone rhythm in male rats.

Prostaglandin mediates endotoxaemia-induced hypophagia by activation of pro-opiomelanocortin and corticotrophin-releasing factor neurons in rats.

Quantitative magnetic resonance imaging evaluation of the olfactory system in Kallmann syndrome: correlation with a clinical smell test.

Regulation of aryl hydrocarbon receptor interacting protein (AIP) protein expression by MiR-34a in sporadic somatotropinomas

Reply to the editor

Sonic Hedgehog mutations are not a common cause of congenital hypopituitarism in the absence of complex midline cerebral defects

Sonic hedgehog signaling is active in human adrenal cortex development and deregulated in adrenocortical tumors

Spindle assembly checkpoint gene expression in childhood adrenocortical tumors (ACT): Overexpression of Aurora kinases A and B is associated with a poor prognosis.

TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood

Telomere length and telomerase expression in pituitary tumors.

The functioning of the hypothalamic-pituitary-adrenal (HPA) axis in postpartum depressive states: a systematic review

Transcriptome Analysis Showed a Differential Signature between Invasive and Non-invasive Corticotrophinomas

Unraveling the expression of the oncogene YAP1, a Wnt/beta-catenin target, in adrenocortical tumors and its association with poor outcome in pediatric patients.