Search filters

List of works by Volker Thiel

2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members

scientific journal article

A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets

scientific article

A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets

A global "imaging'' view on systems approaches in immunology.

scientific article published on December 2012

A highly potent antibody effective against SARS-CoV-2 variants of concern

scientific article published on 21 September 2021

A new era of virus bioinformatics

scientific article published on 08 May 2018

A strategy for the generation of infectious RNAs and autonomously replicating RNAs based on the HCV 229E genome

scientific article published on 01 January 1998

A systems immunology approach to plasmacytoid dendritic cell function in cytopathic virus infections.

scientific article

APOBEC3-mediated restriction of RNA virus replication

scientific article

Antiviral activity of K22 against members of the order Nidovirales.

scientific article published on 11 January 2018

Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission

scientific article published in Scientific Reports

Author Correction: SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation

scientific article published on 20 October 2020

Characterization of a papain-like cysteine-proteinase encoded by gene 1 of the human coronavirus HCV 229E

article

Chimeric feline coronaviruses that encode type II spike protein on type I genetic background display accelerated viral growth and altered receptor usage

scientific article

Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro

scientific article

Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions.

scientific article published on April 2014

Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon

article by L. Cervantes-Barragan et al published 5 October 2006 in Blood

Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation

Cooperation of Th1 and Th17 cells determines transition from autoimmune myocarditis to dilated cardiomyopathy

scientific article published on 13 July 2012

Coronavirus biology and replication: implications for SARS-CoV-2

scientific article published on 28 October 2020

Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines

scientific article

Correction: Functional and Genetic Analysis of Coronavirus Replicase-Transcriptase Proteins

scientific article

Cyclosporin A inhibits the replication of diverse coronaviruses

scientific article

Dendritic Cell-Specific Antigen Delivery by Coronavirus Vaccine Vectors Induces Long-Lasting Protective Antiviral and Antitumor Immunity ⬇️

scientific article published on September 14, 2010

Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling

scientific article published on 11 January 2019

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

scientific article

Disparate temperature-dependent virus – host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

scientific article published on 28 April 2020

Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

scientific article published on 29 March 2021

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

scientific article

Effective amplification of 20-kb DNA by reverse transcription PCR.

scientific article

Efficient inactivation of SARS-CoV-2 by WHO-recommended hand rub formulations and alcohols

scientific article (preprint)

Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential

scientific article

Emergence of a C-terminal seven-amino-acid elongation of NS1 in around 1950 conferred a minor growth advantage to former seasonal influenza A viruses.

scientific article published on 7 August 2013

Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta

scientific article published in February 2022

Establishment of Primary Transgenic Human Airway Epithelial Cell Cultures to Study Respiratory Virus-Host Interactions

scientific article published on 13 August 2019

Evidence for an Ancestral Association of Human Coronavirus 229E with Bats

scientific article published on 16 September 2015

First international external quality assessment of molecular diagnostics for Mers-CoV.

scientific article published on 30 May 2015

Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5

scientific article published on 07 September 2021

Genome organization and reverse genetic analysis of a type I feline coronavirus

scientific article

Host switching pathogens, infectious outbreaks and zoonosis: A Marie Skłodowska-Curie innovative training network (HONOURs) ⬇️

scientific article published in September 2018

Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes

scientific article published on 28 December 2006

Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication

scientific article published on 24 January 2007

ISG56/IFIT1 is primarily responsible for interferon-induced changes to patterns of parainfluenza virus type 5 transcription and protein synthesis

scientific article

Identification and evaluation of coronavirus replicase inhibitors using a replicon cell line

scientific article published on January 2006

Identification of an Antiviral Compound from the Pandemic Response Box that Efficiently Inhibits SARS-CoV-2 Infection In Vitro

scientific article published on 26 November 2020

Identification of five antiviral compounds from the Pandemic Response Box targeting SARS-CoV-2

scientific article published on 18 May 2020

Identification of the mutations responsible for the phenotype of three MHV RNA-negative ts mutants

scientific article published on 01 January 2001

Immune protection against reinfection with nonprimate hepacivirus.

scientific article published on 08 March 2017

Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols

scientific article published on 13 April 2020

Inactivation of Zika virus in human breast milk by prolonged storage or pasteurization

scientific article (publication date: 2017)

Infectious RNA transcribed in vitro from a cDNA copy of the human coronavirus genome cloned in vaccinia virus.

scientific article published in June 2001

Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response.

scientific article

Interferon and cytokine responses to SARS-coronavirus infection

scientific article published on 05 March 2008

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses

scientific article published on 29 October 2013

Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism

scientific article published on 20 February 2013

LY6E impairs coronavirus fusion and confers immune control of viral disease

scientific article (preprint)

LY6E impairs coronavirus fusion and confers immune control of viral disease

scientific article published on 23 July 2020

Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry

scientific article published on 18 March 2020

Link of a ubiquitous human coronavirus to dromedary camels

scientific article published on 15 August 2016

Long distance reverse-transcription PCR.

scientific article

Major genetic marker of nidoviruses encodes a replicative endoribonuclease

scholarly article

Mechanisms and enzymes involved in SARS coronavirus genome expression

scientific article

Multigene RNA vector based on coronavirus transcription.

scientific article

Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase

scientific article

Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis

scientific article

Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants

scientific article published in 2023

New insights on the role of paired membrane structures in coronavirus replication.

scientific article published on 27 December 2014

No Evidence for Human Monocyte-Derived Macrophage Infection and Antibody-Mediated Enhancement of SARS-CoV-2 Infection

scientific article published in 2021

Nucleocapsid Protein Expression Facilitates Coronavirus Replication

scientific article published on 01 January 2006

Organ-specific attenuation of murine hepatitis virus strain A59 by replacement of catalytic residues in the putative viral cyclic phosphodiesterase ns2.

scientific article published on 28 January 2009

Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry

scientific article published on 15 September 2017

Phages bearing affinity peptides to severe acute respiratory syndromes-associated coronavirus differentiate this virus from other viruses.

scientific article

Plasmacytoid dendritic cells control T-cell response to chronic viral infection.

scientific article published on 6 February 2012

Proteolytic processing at the amino terminus of human coronavirus 229E gene 1-encoded polyproteins: identification of a papain-like proteinase and its substrate.

scientific article published on February 1998

Proximity Labeling for the Identification of Coronavirus-Host Protein Interactions

scientific article published on 01 January 2020

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

scientific article (preprint)

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

scientific article published on 04 May 2020

Regulatory T Cells Selectively Preserve Immune Privilege of Self-Antigens during Viral Central Nervous System Infection

scientific article published on 09 March 2012

Replication and transcription of HCV 229E replicons. p6.

scientific article

Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506.

scientific article published on 10 February 2012

Research Models and Tools for the Identification of Antivirals and Therapeutics against Zika Virus Infection

scholarly article by Marco P. Alves et al published 30 October 2018 in Viruses

Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination

scientific article

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

scientific article

SARS-CoV and IFN: Too Little, Too Late.

scientific article

SARS-CoV-2 Inhibition by Sulfonated Compounds

scientific article published on 30 November 2020

SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation

scientific article published on 09 September 2020

SARS-CoV-2 spike D614G change enhances replication and transmission

scientific article

Selective replication of coronavirus genomes that express nucleocapsid protein

scientific article

Sequestration by IFIT1 impairs translation of 2'O-unmethylated capped RNA.

scientific article

Synthetic viruses-Anything new?

scholarly article published by Volker Thiel in 2018

Systems biology of viral infection.

scientific article published in June 2016

TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium

scientific article published on 27 March 2013

Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus

scientific article published in May 2014

Temperature-dependent surface stability of SARS-CoV-2

scientific article published on 03 June 2020

The ADP-ribose-1''-monophosphatase domains of severe acute respiratory syndrome coronavirus and human coronavirus 229E mediate resistance to antiviral interferon responses

scientific article published on 27 April 2011

The International Virus Bioinformatics Meeting 2020

scientific article published on 06 December 2020

The Role of Stress Granules and the Nonsense-mediated mRNA Decay Pathway in Antiviral Defence

scientific article published on 01 May 2019

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors

scientific article

The Small-Compound Inhibitor K22 Displays Broad Antiviral Activity against Different Members of the Family Flaviviridae and Offers Potential as a Panviral Inhibitor

scientific article published on 24 October 2018

The Third Annual Meeting of the European Virus Bioinformatics Center

scientific article published on 05 May 2019

The autocatalytic release of a putative RNA virus transcription factor from its polyprotein precursor involves two paralogous papain-like proteases that cleave the same peptide bond.

scientific article

The differentiated airway epithelium infected by influenza viruses maintains the barrier function despite a dramatic loss of ciliated cells.

scientific article published on 22 December 2016

The quorum sensing com system regulates pneumococcal colonisation and invasive disease in a pseudo-stratified airway tissue model

scientific article published in 2023

The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

scientific article published in 2022

To sense or not to sense viral RNA--essentials of coronavirus innate immune evasion.

scientific article published on 5 June 2014

Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells.

scientific article

Translation of the MHV sM protein is mediated by the internal entry of ribosomes on mRNA 5.

scientific article published on January 1995

Type I IFN-mediated protection of macrophages and dendritic cells secures control of murine coronavirus infection

scientific article

Viral RNA in an m6A disguise

scientific article published on 01 April 2020

Virologists-Heroes need weapons.

scientific article published on 8 February 2018

Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses

scientific article

Paulina is supported by:

About Paulina

Help