List of works - Yuet-Kin Leung

A community survey on knowledge of the impact of environmental and epigenetic factors on health and disease

scientific article

AP-2 regulates the transcription of estrogen receptor (ER)-beta by acting through a methylation hotspot of the 0N promoter in prostate cancer cells

scientific article published on 21 May 2007

Activation of p53 by specific agents in potential cancer therapy.

scientific article

Bisphenol A (BPA) stimulates the interferon signaling and activates the inflammasome activity in myeloid cells

scientific article

Calcium phosphate-polymer hybrid nanoparticles for enhanced triple negative breast cancer treatment via co-delivery of paclitaxel and miR-221/222 inhibitors.

scientific article published on 9 August 2016

Cloning and characterization of chironomidae ferrochelatase: copper activation of the purified ferrochelatase.

scientific article published in July 2004

Comprehensive mapping of the methylation landscape of 16 CpG-dense regions in oral and pharyngeal squamous cell carcinoma

scientific article published on 19 June 2019

DNA methylome changes by estradiol benzoate and bisphenol A links early-life environmental exposures to prostate cancer risk

scientific article published on 14 July 2016

Data on spermatogenesis in rat males gestationally exposed to bisphenol A and high fat diets.

scientific article

Deciphering signaling control by phosphoproteome using mass spectrometry.

scientific article published on January 2006

Differential expression of estrogen receptor beta isoforms in prostate cancer through interplay between transcriptional and translational regulation

scientific article

Differential methylation values in differential methylation analysis

scientific article published on 01 April 2019

Does epigenetic drift contribute to age-related increases in breast cancer risk?

scientific article

Effects of High-Butterfat Diet on Embryo Implantation in Female Rats Exposed to Bisphenol A

scientific article

Endocrine disruption of the epigenome: a breast cancer link.

scientific article published on 12 March 2014

Environmental factors, epigenetics, and developmental origin of reproductive disorders

scientific article

Environmental manganese exposure in residents living near a ferromanganese refinery in Southeast Ohio: a pilot study

scientific article

Estrogen activates pyruvate kinase M2 and increases the growth of TSC2-deficient cells

scientific article published on 20 February 2020

Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signaling

scientific article

Estrogen receptor beta2 and beta5 are associated with poor prognosis in prostate cancer, and promote cancer cell migration and invasion.

scientific article

Estrogen receptor β isoform 5 confers sensitivity of breast cancer cell lines to chemotherapeutic agent-induced apoptosis through interaction with Bcl2L12.

scientific article

Estrogen receptor β: switching to a new partner and escaping from estrogen

scientific article

Estrogen receptor-beta and breast cancer: translating biology into clinical practice

scientific article

Estrogens and antiestrogens as etiological factors and therapeutics for prostate cancer.

scientific article published on November 2006

Estrogens and prostate cancer: etiology, mediators, prevention, and management.

scientific article

Evaluating endocrine disruption activity of deposits on firefighting gear using a sensitive and high throughput screening method

journal article published in 2015

Exposure of Human Prostaspheres to Bisphenol A Epigenetically Regulates SNORD Family Noncoding RNAs via Histone Modification

scientific article

Forkhead box protein 3 (FOXP3) hypermethylation is associated with diesel exhaust exposure and risk for childhood asthma

scientific article published on 20 December 2012

Herceptin conjugated PLGA-PHis-PEG pH sensitive nanoparticles for targeted and controlled drug delivery.

scientific article

High butter-fat diet and bisphenol A additively impair male rat spermatogenesis.

scientific article published on 19 September 2016

Hsa-miRNA-765 as a key mediator for inhibiting growth, migration and invasion in fulvestrant-treated prostate cancer

scientific article

ICI 182,780-regulated gene expression in DU145 prostate cancer cells is mediated by estrogen receptor-beta/NFkappaB crosstalk.

scientific article

Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort

scientific article published on 16 May 2018

In utero exposure of rats to high-fat diets perturbs gene expression profiles and cancer susceptibility of prepubertal mammary glands

scientific article published on 26 November 2015

Induction of UDP-glucuronosyltransferase 1A8 mRNA by 3-methylcholanthene in rat hepatoma cells

scientific journal article

Inhibition Role of Atherogenic Diet on Ethyl Carbamate Induced Lung Tumorigenesis in C57BL/6J Mice.

scientific article

Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer

scientific article published on 6 September 2017

Methylation of a single intronic CpG mediates expression silencing of the PMP24 gene in prostate cancer

scientific article published on May 2010

Modulation of reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by vitamin C-palmitate

scientific article published on 01 December 1999

NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries

scientific article published on 16 April 2019

Offspring sex impacts DNA methylation and gene expression in placentae from women with diabetes during pregnancy.

scientific article

Overexpression of cytochrome P450 1A1 and its novel spliced variant in ovarian cancer cells: alternative subcellular enzyme compartmentation may contribute to carcinogenesis.

scientific article

Phosphorylation of human estrogen receptor-beta at serine 105 inhibits breast cancer cell migration and invasion.

scientific article

Prostate Cancer Expression Profiles of Cytoplasmic ERβ1 and Nuclear ERβ2 are Associated with Poor Outcomes following Radical Prostatectomy.

scientific article published on 21 January 2016

Quantitative comparison and reproducibility of pathologist scoring and digital image analysis of estrogen receptor β2 immunohistochemistry in prostate cancer

scientific article

Sex-specific regulation of collagen I and III expression by 17β-Estradiol in cardiac fibroblasts: role of estrogen receptors

scientific article published on 01 February 2019

The transcriptional repressor ZBTB4 regulates EZH2 through a MicroRNA-ZBTB4-specificity protein signaling axis

scientific article

Transcriptional regulation of fosl-1 by licorice in rat Clone 9 cells.

scientific article published in October 2003

Unique bisphenol A transcriptome in prostate cancer: novel effects on ERbeta expression that correspond to androgen receptor mutation status

scientific article

oxBS-MLE: an efficient method to estimate 5-methylcytosine and 5-hydroxymethylcytosine in paired bisulfite and oxidative bisulfite treated DNA.

scientific article

List of works by Yuet-Kin Leung

A community survey on knowledge of the impact of environmental and epigenetic factors on health and disease

AP-2 regulates the transcription of estrogen receptor (ER)-beta by acting through a methylation hotspot of the 0N promoter in prostate cancer cells

Activation of p53 by specific agents in potential cancer therapy.

Bisphenol A (BPA) stimulates the interferon signaling and activates the inflammasome activity in myeloid cells

Calcium phosphate-polymer hybrid nanoparticles for enhanced triple negative breast cancer treatment via co-delivery of paclitaxel and miR-221/222 inhibitors.

Cloning and characterization of chironomidae ferrochelatase: copper activation of the purified ferrochelatase.

Comprehensive mapping of the methylation landscape of 16 CpG-dense regions in oral and pharyngeal squamous cell carcinoma

DNA methylome changes by estradiol benzoate and bisphenol A links early-life environmental exposures to prostate cancer risk

Data on spermatogenesis in rat males gestationally exposed to bisphenol A and high fat diets.

Deciphering signaling control by phosphoproteome using mass spectrometry.

Differential expression of estrogen receptor beta isoforms in prostate cancer through interplay between transcriptional and translational regulation

Differential methylation values in differential methylation analysis

Does epigenetic drift contribute to age-related increases in breast cancer risk?

Effects of High-Butterfat Diet on Embryo Implantation in Female Rats Exposed to Bisphenol A

Endocrine disruption of the epigenome: a breast cancer link.

Environmental factors, epigenetics, and developmental origin of reproductive disorders

Environmental manganese exposure in residents living near a ferromanganese refinery in Southeast Ohio: a pilot study

Estrogen activates pyruvate kinase M2 and increases the growth of TSC2-deficient cells

Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signaling

Estrogen receptor beta2 and beta5 are associated with poor prognosis in prostate cancer, and promote cancer cell migration and invasion.

Estrogen receptor β isoform 5 confers sensitivity of breast cancer cell lines to chemotherapeutic agent-induced apoptosis through interaction with Bcl2L12.

Estrogen receptor β: switching to a new partner and escaping from estrogen

Estrogen receptor-beta and breast cancer: translating biology into clinical practice

Estrogens and antiestrogens as etiological factors and therapeutics for prostate cancer.

Estrogens and prostate cancer: etiology, mediators, prevention, and management.

Evaluating endocrine disruption activity of deposits on firefighting gear using a sensitive and high throughput screening method

Exposure of Human Prostaspheres to Bisphenol A Epigenetically Regulates SNORD Family Noncoding RNAs via Histone Modification

Forkhead box protein 3 (FOXP3) hypermethylation is associated with diesel exhaust exposure and risk for childhood asthma

Herceptin conjugated PLGA-PHis-PEG pH sensitive nanoparticles for targeted and controlled drug delivery.

High butter-fat diet and bisphenol A additively impair male rat spermatogenesis.

Hsa-miRNA-765 as a key mediator for inhibiting growth, migration and invasion in fulvestrant-treated prostate cancer

ICI 182,780-regulated gene expression in DU145 prostate cancer cells is mediated by estrogen receptor-beta/NFkappaB crosstalk.

Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort

In utero exposure of rats to high-fat diets perturbs gene expression profiles and cancer susceptibility of prepubertal mammary glands

Induction of UDP-glucuronosyltransferase 1A8 mRNA by 3-methylcholanthene in rat hepatoma cells

Inhibition Role of Atherogenic Diet on Ethyl Carbamate Induced Lung Tumorigenesis in C57BL/6J Mice.

Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer

Methylation of a single intronic CpG mediates expression silencing of the PMP24 gene in prostate cancer

Modulation of reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by vitamin C-palmitate

NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries

Offspring sex impacts DNA methylation and gene expression in placentae from women with diabetes during pregnancy.

Overexpression of cytochrome P450 1A1 and its novel spliced variant in ovarian cancer cells: alternative subcellular enzyme compartmentation may contribute to carcinogenesis.

Phosphorylation of human estrogen receptor-beta at serine 105 inhibits breast cancer cell migration and invasion.

Prostate Cancer Expression Profiles of Cytoplasmic ERβ1 and Nuclear ERβ2 are Associated with Poor Outcomes following Radical Prostatectomy.

Quantitative comparison and reproducibility of pathologist scoring and digital image analysis of estrogen receptor β2 immunohistochemistry in prostate cancer

Sex-specific regulation of collagen I and III expression by 17β-Estradiol in cardiac fibroblasts: role of estrogen receptors

The transcriptional repressor ZBTB4 regulates EZH2 through a MicroRNA-ZBTB4-specificity protein signaling axis

Transcriptional regulation of fosl-1 by licorice in rat Clone 9 cells.

Unique bisphenol A transcriptome in prostate cancer: novel effects on ERbeta expression that correspond to androgen receptor mutation status

oxBS-MLE: an efficient method to estimate 5-methylcytosine and 5-hydroxymethylcytosine in paired bisulfite and oxidative bisulfite treated DNA.