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List of works by Carol A. Gross

A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S

scientific article

A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria

scientific article

A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

scientific article

A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation

scientific article

A chaperone network controls the heat shock response in E. coli

scientific article published on November 2004

A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli.

scientific article published on March 1989

A hydrophobic patch on the flap-tip helix of E.coli RNA polymerase mediates sigma(70) region 4 function

scientific article published in October 2004

A mutant sigma 32 with a small deletion in conserved region 3 of sigma has reduced affinity for core RNA polymerase ⬇️

scientific article published on August 1, 1992

A pause sequence enriched at translation start sites drives transcription dynamics in vivo

scientific article

Accumulation of secretory protein precursors in Escherichia coli induces the heat shock response

scientific article

Altered promoter recognition by mutant forms of the sigma 70 subunit of Escherichia coli RNA polymerase

scientific article published on 01 April 1989

Altering the interaction between sigma70 and RNA polymerase generates complexes with distinct transcription-elongation properties

scientific article

Amino-terminal amino acids modulate sigma-factor DNA-binding activity

scientific article published on 01 December 1993

An extra-cytoplasmic function sigma factor and anti-sigma factor control carotenoid biosynthesis in Azospirillum brasilense

scientific article

An open letter to Elias Zerhouni

scientific article published on 01 March 2005

Analysis of sigma32 mutants defective in chaperone-mediated feedback control reveals unexpected complexity of the heat shock response

scholarly article

Analyzing the interaction of RseA and RseB, the two negative regulators of the sigmaE envelope stress response, using a combined bioinformatic and experimental strategy

scientific article published on 22 December 2008

Assay of Escherichia coli RNA polymerase: sigma-core interactions

scientific article

Bacterial CRISPR screens for gene function

scientific article published on 04 December 2020

Bacterial CRISPR: accomplishments and prospects.

scientific article

Bacterial sigma factors: a historical, structural, and genomic perspective

scientific article published on 18 June 2014

Characterization of six lipoproteins in the sigmaE regulon

scientific article

Characterization of the termination phenotypes of rifampicin-resistant mutants

scientific article published on 01 July 1988

Conserved and variable functions of the sigmaE stress response in related genomes

scientific article

Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis

scientific article

Convergence of Molecular, Modeling, and Systems Approaches for an Understanding of the Escherichia coli Heat Shock Response ⬇️

scientific article (publication date: September 2008)

Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division

scientific article published on 7 May 2015

Correction: A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S

scientific article published on 21 July 2017

Covalent Intermediate in the Catalytic Mechanism of the Radical S-Adenosyl-l-methionine Methyl Synthase RlmN Trapped by Mutagenesis ⬇️

scientific article published on October 22, 2012

Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA

scientific article (publication date: April 2003)

DegS and YaeL participate sequentially in the cleavage of RseA to activate the sigma(E)-dependent extracytoplasmic stress response

scientific article published on August 2002

Depletion of Undecaprenyl Pyrophosphate Phosphatases Disrupts Cell Envelope Biogenesis in Bacillus subtilis.

scientific article

Design of orthogonal genetic switches based on a crosstalk map of σs, anti-σs, and promoters

scientific article published on 29 October 2013

Design principles of the proteolytic cascade governing the sigmaE-mediated envelope stress response in Escherichia coli: keys to graded, buffered, and rapid signal transduction.

scientific article published on January 2007

Directed evolution of substrate-optimized GroEL/S chaperonins

article

Discovery of the extracytoplasmic function σ factors

scientific article published on 17 June 2019

Dissection of recognition determinants of Escherichia coli sigma32 suggests a composite -10 region with an 'extended -10' motif and a core -10 element

scientific article published on 14 April 2009

DksA regulates RNA polymerase in Escherichia coli through a network of interactions in the secondary channel that includes Sequence Insertion 1

scientific article

DnaK, DnaJ, and GrpE are required for flagellum synthesis in Escherichia coli ⬇️

scientific article published on October 1, 1992

Dual Molecular Signals Mediate the Bacterial Response to Outer-Membrane Stress ⬇️

scientific article published on May 17, 2013

Editorial overview: Cell regulation: when you think you know it all, there is another layer to be discovered

scientific article

Effects of the mutant sigma allele rpoD800 on the synthesis of specific macromolecular components of the Escherichia coli K12 cell

scientific article published on 01 January 1984

Enabling genetic analysis of diverse bacteria with Mobile-CRISPRi

scientific article published on 07 January 2019

Expansion and re-classification of the extracytoplasmic function (ECF) σ factor family

scientific article published on 04 January 2021

Fine-tuning of the Escherichia coli sigmaE envelope stress response relies on multiple mechanisms to inhibit signal-independent proteolysis of the transmembrane anti-sigma factor, RseA.

scientific article published on November 2004

From the regulation of peptidoglycan synthesis to bacterial growth and morphology.

scientific article

Genes and enzymes of azetidine-2-carboxylate metabolism: detoxification and assimilation of an antibiotic

scientific article

Genetic interaction mapping informs integrative structure determination of protein complexes

scientific article published on 01 December 2020

Global analysis of translation termination in E. coli.

scientific article

Heat shock transcription factor σ32 co-opts the signal recognition particle to regulate protein homeostasis in E. coli

scientific article

Hfq modulates the sigmaE-mediated envelope stress response and the sigma32-mediated cytoplasmic stress response in Escherichia coli

scientific article

High-throughput bacterial functional genomics in the sequencing era

scientific article published on 31 August 2015

High-throughput, quantitative analyses of genetic interactions in E. coli

scientific article

How a mutation in the gene encoding sigma 70 suppresses the defective heat shock response caused by a mutation in the gene encoding sigma 32.

scientific article

Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component.

scientific article

Identification of the binding sites of regulatory proteins in bacterial genomes

scientific article

Identification of the sigma E subunit of Escherichia coli RNA polymerase: a second alternate sigma factor involved in high-temperature gene expression

scientific article published in September 1989

Impact of genomic technologies on studies of bacterial gene expression

scientific article

Insights into transcriptional regulation and sigma competition from an equilibrium model of RNA polymerase binding to DNA

scholarly article

Involvement of the DnaK-DnaJ-GrpE chaperone team in protein secretion in Escherichia coli

scientific article published on June 1996

Isolation and characterization of Escherichia coli mutants that lack the heat shock sigma factor sigma 32.

scientific article

Lack of a robust unfoldase activity confers a unique level of substrate specificity to the universal AAA protease FtsH.

scientific article

Mapping and sequencing of mutations in the Escherichia colirpoB gene that lead to rifampicin resistance

scientific article (publication date: July 1988)

Marine Mammal Microbiota Yields Novel Antibiotic with Potent Activity Against Clostridium difficile. ⬇️

scientific article published on 18 October 2017

MicL, a new σE-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein

scientific article (publication date: 15 July 2014)

Minimal machinery of RNA polymerase holoenzyme sufficient for promoter melting

scientific article

Mismatch-CRISPRi Reveals the Co-varying Expression-Fitness Relationships of Essential Genes in Escherichia coli and Bacillus subtilis

scientific article published on 15 October 2020

Module-based analysis of robustness tradeoffs in the heat shock response system

scientific article published on 13 April 2006

Multiple Sigma Subunits and the Partitioning of Bacterial Transcription Space ⬇️

scientific article published on January 1, 2003

MurJ and a novel lipid II flippase are required for cell wall biogenesis in Bacillus subtilis.

scientific article published on 27 April 2015

Mutational analysis of Escherichia coli sigma28 and its target promoters reveals recognition of a composite -10 region, comprised of an 'extended -10' motif and a core -10 element.

scientific article published on 14 April 2009

Mutations in rpoD that increase expression of genes in the mal regulon of Escherichia coli K-12

scientific article published on 01 September 1988

OMP peptide signals initiate the envelope-stress response by activating DegS protease via relief of inhibition mediated by its PDZ domain

scientific article

Operon mRNAs are organized into ORF-centric structures that predict translation efficiency.

scientific article published on 31 January 2017

Partial loss of function mutations in DnaK, the Escherichia coli homologue of the 70-kDa heat shock proteins, affect highly conserved amino acids implicated in ATP binding and hydrolysis ⬇️

scientific article published on August 1, 1992

Phenotypic landscape of a bacterial cell

scientific article

Physiological effects of the fructose-1,6-diphosphate aldolase ts8 mutation on stable RNA synthesis in Escherichia coli ⬇️

scientific article published on October 1, 1991

Predicting the strength of UP-elements and full-length E. coli σE promoters

scientific article published on 8 December 2011

Promoter melting by an alternative σ, one base at a time

scientific article published on April 2014

Promoter strength properties of the complete sigma E regulon of Escherichia coli and Salmonella enterica

scientific article published on 25 September 2009

Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources

scientific article

Reduced capacity of alternative sigmas to melt promoters ensures stringent promoter recognition

scientific article published on October 2009

Regulation of peptidoglycan synthesis by outer-membrane proteins

scientific article published on December 2010

Regulation of the Escherichia coli sigma-dependent envelope stress response

scientific article published on May 2004

Regulation of the alternative sigma factor sigma(E) during initiation, adaptation, and shutoff of the extracytoplasmic heat shock response in Escherichia coli

scientific article

Regulon and promoter analysis of the E. coli heat-shock factor, sigma32, reveals a multifaceted cellular response to heat stress

scientific article

Resistance to serine in Bacillus subtilis: Identification of the serine transporter YbeC and of a metabolic network that links serine and threonine metabolism

scientific article published on 02 August 2020

Rewiring the specificity of extracytoplasmic function sigma factors

scientific article published on 14 December 2020

Ribosomal Architecture: Constraints Imposed by the Need for Self-Production.

scientific article

Selective ribosome profiling reveals the cotranslational chaperone action of trigger factor in vivo

scientific article

Signal integration by DegS and RseB governs the σ E-mediated envelope stress response in Escherichia coli

scientific article

Small RNAs endow a transcriptional activator with essential repressor functions for single-tier control of a global stress regulon

scientific article (publication date: 2 August 2011)

Stress-induced remodeling of the bacterial proteome

scientific article published on May 2014

Stringent response in Escherichia coli induces expression of heat shock proteins

scientific article published on 01 November 1985

Structure and Function of the Transmembrane Domain of NsaS, an Antibiotic Sensing Histidine Kinase in Staphylococcus aureus.

scientific article

The 2000 Thomas Hunt Morgan Medal. Evelyn M. Witkin

scientific article (publication date: February 2001)

The Escherichia coli ts8 mutation is an allele of fda, the gene encoding fructose-1,6-diphosphate aldolase

scientific article published on October 1991

The crystal structure Escherichia coli Spy ⬇️

scientific article published on November 1, 2010

The crystal structure of the periplasmic domain ofVibrio parahaemolyticusCpxA

scientific article

The htpR gene product of E. coli is a sigma factor for heat-shock promoters

scientific article published on 01 September 1984

The sigma subunit of Escherichia coli RNA polymerase senses promoter spacing

scientific article published on August 1996

Three-dimensional biofilm colony growth supports a mutualism involving matrix and nutrient sharing

scientific article published on 17 February 2021

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs

scientific article published on 13 January 2020

Topoisomerase IV can functionally replace all type 1A topoisomerases in Bacillus subtilis.

scientific article

Transcription from a heat-inducible promoter causes heat shock regulation of the sigma subunit of E. coli RNA polymerase

scientific article published on 01 September 1984

Unexpected Stress-Reducing Effect of PhaP, a Poly(3-Hydroxybutyrate) Granule-Associated Protein, in Escherichia coli ⬇️

scientific article published on July 22, 2011

Using DNA microarrays to assay part function

scientific article

Views of transcription initiation

scientific article

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