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List of works by Rafael Esteban

1990-2010: two decades of interferon-based therapy

scientific article published on June 14, 2011

A comparative study of ultra-deep pyrosequencing and cloning to quantitatively analyze the viral quasispecies using hepatitis B virus infection as a model

scientific article published on 20 March 2013

A cost-effectiveness analysis of peginterferon alfa-2b plus ribavirin for the treatment of naive patients with chronic hepatitis C.

scientific article published in March 2003

Adding banding ligation is effective as rescue therapy to prevent variceal rebleeding in haemodynamic non-responders to pharmacological therapy ⬇️

scientific article published on September 3, 2011

Adherence to assigned dosing regimen and sustained virological response among chronic hepatitis C genotype 1 patients treated with boceprevir plus peginterferon alfa‐2b/ribavirin ⬇️

scientific article published on May 26, 2013

Alcohol consumption and risk of infection after a variceal bleeding in low-risk patients

scientific article published on 8 December 2015

Analysis of hepatitis B genotype changes in chronic hepatitis B infection: Influence of antiviral therapy

scientific article published on 6 May 2008

Analysis of hepatitis B virus preS1 variability and prevalence of the rs2296651 polymorphism in a Spanish population

scientific article published on 14 February 2018

Anti-hepatitis-A antibody in Spain

scientific article published on 01 September 1978

Applicability of real-time PCR combined with melting curve analysis for the study of hepatitis B virus genome mutations

scientific article published in February 2003

Are recipients of solid organ transplantation a high-risk population for hepatitis E virus infection?

scientific article published on 01 January 2010

Assessment of the PCR-Southern blot technique for the analysis of viremia in patients with acute hepatitis A

scientific article

Atrophy of mesenteric sympathetic innervation may contribute to splanchnic vasodilation in rat portal hypertension.

scientific article published on 30 November 2009

Baseline HCV-RNA levels in genotype 1 chronic hepatitis C patients: The role of different cut-off points

scientific article published on 11 March 2016

Blockage of the afferent sensitive pathway prevents sympathetic atrophy and hemodynamic alterations in rat portal hypertension.

scientific article published on 31 January 2012

Boceprevir for previously treated chronic HCV genotype 1 infection

scientific article

Can interferon prolong life?

scientific article published on 01 August 2003

Cardiac alterations in cirrhosis: reversibility after liver transplantation

scientific article published on 01 January 2005

Chronic delta infection in a patient without detectable HBsAg in serum

scientific article published on 01 July 1988

Cirrhosis, liver transplantation and HIV infection are risk factors associated with hepatitis E virus infection

scientific article

Clinical application of estimating hepatitis B virus quasispecies complexity by massive sequencing: correlation between natural evolution and on-treatment evolution

scientific article

Clinical impact and efficacy of lamivudine therapy in de novo hepatitis B infection after liver transplantation

scientific article published in October 2002

Clinical outcome of acute and chronic hepatitis delta over time: a long-term follow-up study

scientific article published on 01 June 2011

Clinical outcome of lamivudine-resistant chronic hepatitis B patients with compensated cirrhosis under adefovir salvage treatment. Importance of HCC surveillance.

scientific article published in September 2009

Combined treatment with pegylated interferon (alpha-2b) and ribavirin in the acute phase of hepatitis C virus recurrence after liver transplantation

scientific article published on 11 April 2005

Community-based seroepidemiological survey of hepatitis E virus infection in Catalonia, Spain

scientific article

Comparative analysis of serological markers of chronic delta infection: HDV-RNA, serum HDAg and anti-HD IgM

scientific article published on 01 December 1994

Complex Genotype Mixtures Analyzed by Deep Sequencing in Two Different Regions of Hepatitis B Virus

scientific article published on 29 December 2015

Consensus document of the Spanish Association for the Study of the Liver on the treatment of hepatitis B infection (2012)

scientific article published on 29 June 2012

Correction for Quer at al., High-Resolution Hepatitis C Virus Subtyping Using NS5B Deep Sequencing and Phylogeny, an Alternative to Current Methods

scientific article published on July 2016

Cost-effectiveness analysis of lamivudine and adefovir dipivoxil in the treatment of patients with HBeAg-negative chronic hepatitis B.

scientific article published in February 2006

Cost-effectiveness analysis of ledipasvir/sofosbuvir in patients with chronic hepatitis C: Treatment of patients with absence or mild fibrosis compared to patients with advanced fibrosis.

scientific article published on 8 March 2017

Cost-effectiveness of a hepatitis B virus screening strategy to prevent reactivation in patients with hematologic neoplasms.

scientific article

Cost-effectiveness of boceprevir in patients previously treated for chronic hepatitis C genotype 1 infection in the United States

scientific article published on September 2013

Cuantificación del antígeno de superficie del virus de la hepatitis B: implicaciones clínicas

scientific article published on 29 June 2011

Current trends in chronic hepatitis B management: results of a questionnaire.

scientific article published in October 2009

De novo nephrotic syndrome following pegylated interferon alfa 2b/ribavirin therapy for chronic hepatitis C infection.

scientific article published in January 2008

Delta agent in nondrug addicts

scientific article published on 01 May 1985

Detection of early portal hypertension with routine data and liver stiffness in patients with asymptomatic liver disease: a prospective study

scientific article

Detection of hepatitis B precore mutants by the fluorescent linear polymerase chain reaction sequencing method.

scientific article

Development of a clinical hepatic encephalopathy staging scale

scientific article published on 01 September 2007

Down-regulation of genes related to the adrenergic system may contribute to splanchnic vasodilation in rat portal hypertension.

scientific article published on 18 April 2008

Droxidopa, an oral norepinephrine precursor, improves hemodynamic and renal alterations of portal hypertensive rats

scientific article published on 14 October 2012

Drug-induced lupus-like reaction and captopril

scientific article published on 01 December 1993

Drugs in development for hepatitis B.

scientific article

Early Pleural Effusion in Histiocytosis X ⬇️

scientific article published on August 1, 1979

Effect of bottlenecking on evolution of the nonstructural protein 3 gene of hepatitis C virus during sexually transmitted acute resolving infection

scientific article

Effectiveness and Safety of Entecavir or Tenofovir in a Spanish Cohort of Chronic Hepatitis B Patients: Validation of the Page-B Score to Predict Hepatocellular Carcinoma

scientific article published on 11 January 2017

Effectiveness and safety of sofosbuvir-based regimens plus an NS5A inhibitor for patients with HCV genotype 3 infection and cirrhosis. Results of a multicenter real-life cohort

scientific article

Effectiveness of combined pharmacologic and ligation therapy in high-risk patients with acute esophageal variceal bleeding

scientific article published on 31 May 2011

Effects of Branched-Chain Amino Acids Supplementation in Patients With Cirrhosis and a Previous Episode of Hepatic Encephalopathy: A Randomized Study

article

Effects of different dose levels and vaccination schedules on immune response to a recombinant DNA hepatitis B vaccine in haemodialysis patients

scientific article published on 01 March 1990

Effects of intravenous albumin in patients with cirrhosis and episodic hepatic encephalopathy: a randomized double-blind study.

scientific article

Efficacy and safety of boceprevir plus peginterferon-ribavirin in patients with HCV G1 infection and advanced fibrosis/cirrhosis

scientific article

Efficacy and tolerance of a combination of tenofovir disoproxil fumarate plus emtricitabine in patients with chronic hepatitis B: a European multicenter study.

scientific article published on 13 July 2011

Efficacy of Sofosbuvir and Velpatasvir, With and Without Ribavirin, in Patients With Hepatitis C Virus Genotype 3 Infection and Cirrhosis

scientific article published on 27 June 2018

Efficacy of screening donors for antibodies to the hepatitis C virus to prevent transfusion-associated hepatitis: Final report of a prospective trial ⬇️

scientific article published on August 1, 1995

Epidemiology of hepatitis C virus infection

scientific article published on 01 January 1993

European collaborative study on factors influencing outcome after liver transplantation for hepatitis C. European Concerted Action on Viral Hepatitis (EUROHEP) Group.

scientific article published in September 1999

Evidence of an Exponential Decay Pattern of the Hepatitis Delta Virus Evolution Rate and Fluctuations in Quasispecies Complexity in Long-Term Studies of Chronic Delta Infection

scientific article

Extending combination therapy with peginterferon alfa-2b plus ribavirin for genotype 1 chronic hepatitis C late responders: A report of 9 cases ⬇️

scientific article published on May 1, 2003

Genetic alterations in the S gene of hepatitis B virus in patients with acute hepatitis B, chronic hepatitis B and hepatitis B liver cirrhosis before and after liver transplantation.

scientific article published in June 1999

Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients

scientific article

HBV core region variability: effect of antiviral treatments on main epitopic regions

scientific article published in January 2011

Hemodynamic response-guided therapy for prevention of variceal rebleeding: an uncontrolled pilot study

scientific article published on 01 October 2006

Hemoperitoneum as a first manifestation of hepatocellular carcinoma in western patients with liver cirrhosis: effectiveness of emergency treatment with transcatheter arterial embolization.

scientific article

Hepatitis B virus and hepatitis D virus replication in HBsAg-positive fulminant hepatitis.

scientific article

Hepatitis B virus genome variability and disease progression: the impact of pre-core mutants and HBV genotypes

scientific article

Hepatitis B virus genotypes and G1896A precore mutation in 486 Spanish patients with acute and chronic HBV infection.

scientific article published in May 2006

Hepatitis B virus polymerase variants associated with entecavir drug resistance in treatment-naive patients.

scientific article published in December 2007

Hepatitis B virus quasispecies evolution after liver transplantation in patients under long-term lamivudine prophylaxis with or without hepatitis B immune globulin

scientific article published on April 2015

Hepatitis B-associated membranous glomerulonephritis treated with adenine arabinoside monophosphate

scientific article published on 01 July 1986

Hepatitis C virus Core Antigen as a predictor of non-response in genotype 1 chronic hepatitis C patients treated with peginterferon alpha-2b plus ribavirin

scientific article published on March 2004

Hepatitis C virus genotype 3: a genotype that is not 'easy-to-treat'.

scientific article published on 15 September 2014

Hepatitis C virus genotype 4: Genotype 1's little brother.

scientific article published on December 2016

Hepatitis E infection in acute sporadic hepatitis in Spain

scientific article published in The Lancet

Hepatitis delta genotypes in chronic delta infection in the northeast of Spain (Catalonia)

article

Hepatocellular carcinoma and hepatitis B virus markers in Europe ⬇️

scientific article published on March 31, 1979

High-Dose interferon-alpha2b plus ribavirin for retreatment of interferon-nonresponsive patients infected with genotype 1 hepatitis C virus.

scientific article published in November 2001

High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods

scientific article

Hypercholesterolemia in long-term survivors of liver transplantation: a comparison between cyclosporine and FK 506

scientific article published on 01 June 1998

Immunogenicity of a yeast-derived hepatitis B vaccine in hemodialysis patients

Implementing universal vaccination programmes: Spain

scientific article published on 01 January 1995

Improved attachment of natural HCV isolate to Daudi cells upon elimination of immune complexes and close pH control

scientific article published on September 2005

Incidence and predictors of hepatocellular carcinoma in Caucasian chronic hepatitis B patients receiving entecavir or tenofovir

scientific article published on 06 September 2014

Increased tumour necrosis factor alpha production in mesenteric lymph nodes of cirrhotic patients with ascites

scientific article published on July 2003

Influence of human immunodeficiency virus infection on cell-mediated immunity in chronic D hepatitis.

scientific article published in June 1991

Infrequent detection of hepatitis E virus RNA in pregnant women with hepatitis E virus antibodies in Spain

scientific article published in November 2010

Inhibition of neuronal apoptosis and axonal regression ameliorates sympathetic atrophy and hemodynamic alterations in portal hypertensive rats

scientific article published on 6 January 2014

Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group

scientific article (publication date: 19 November 1998)

Interferon vs. adenine arabinoside 5'-monophosphate in patients with anti-HBe-positive chronic hepatitis

scientific article published on 01 August 1996

Interferon-free therapies for patients with chronic hepatitis C genotype 3 infection: A systematic review.

scientific article published on 07 December 2016

Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response.

scientific article

Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus

scientific article

Interleukin-6, nitric oxide, and the clinical and hemodynamic alterations of patients with liver cirrhosis

scientific article published on 01 January 1999

Introduction: thrombocytopenia in chronic liver disease -- treatment implications and novel approaches.

scientific article

Is hepatitis B virus subtype testing useful in predicting virological response and resistance to lamivudine?

scientific article published in March 2002

Is there a role for interferon in acute viral hepatitis?

scientific article

Letters to the Editor

scientific article published on 01 February 2000

Liver transplantation in HIV-HCV coinfected patients: a case-control study

scientific article published in February 2007

Long-term clearance of hepatitis C virus following interferon α-2b or peginterferon α-2b, alone or in combination with ribavirin.

scientific article published on 3 March 2013

Long-term clinical outcomes in patients with chronic hepatitis delta: the role of persistent viraemia

scientific article published on 13 November 2019

Long-term follow-up of hemodynamic responders to pharmacological therapy after variceal bleeding.

scientific article

Long-term safety and efficacy of nucleo(t)side analogue therapy in hepatitis B.

scientific article published in February 2018

Management of direct antiviral agent failures.

scientific article published on 25 December 2016

Management of direct-acting antiviral agent failures

scientific article published on 19 August 2015

Management of hepatitis C virus genotype 4: recommendations of an international expert panel.

scientific article published on 08 December 2010

Materno-fetal transmission of hepatitis A antibody

scientific article published on 01 July 1980

Modeling the cost-effectiveness of different oral antiviral therapies in patients with chronic hepatitis B.

scientific article

Molecular epidemiology and putative origin of hepatitis C virus in random volunteers from Argentina

scientific article published on September 2013

Mutations in the basic core promoter region of hepatitis B virus. Relationship with precore variants and HBV genotypes in a Spanish population of HBV carriers.

scientific article

Naturally occurring NS3-protease-inhibitor resistant mutant A156T in the liver of an untreated chronic hepatitis C patient

scientific article published on 19 November 2007

New hepatitis C virus genotype 1 subtype naturally harbouring resistance-associated mutations to NS5A inhibitors

scientific article published on 14 December 2017

New therapeutic perspectives in HBV: when to stop NAs.

scientific article published on February 2014

Nitric oxide may contribute to nocturnal hemodynamic changes in cirrhotic patients

scientific article published on 01 June 2000

Normal protein diet for episodic hepatic encephalopathy: results of a randomized study.

scientific article published in July 2004

Oral glutamine challenge and magnetic resonance spectroscopy in three patients with congenital portosystemic shunts.

scientific article

PAGE-B predicts the risk of developing hepatocellular carcinoma in Caucasians with chronic hepatitis B on 5-year antiviral therapy.

scientific article published on 8 December 2015

Patient experience in HCV therapy: what really matters.

scientific article published on 3 August 2016

Position paper of the Catalan Society of Gastroenterology: treatment of Genotype 1 Chronic Hepatitis C Virus with Triple Therapy

scientific article published on 3 May 2012

Predicting early mortality after acute variceal hemorrhage based on classification and regression tree analysis.

scientific article published on 21 August 2009

Preparing the patient for success: treat or wait?

scientific article published on September 2013

Quality of life in cirrhosis is related to potentially treatable factors

scientific article published in February 2010

Quantitative characterization of hepatitis delta virus genome edition by next-generation sequencing

scientific article published on 4 October 2017

Quantitative detection of hepatitis B virus DNA in serum by a new rapid real-time fluorescence PCR assay.

scientific article

Quantitative longitudinal evaluations of hepatitis delta virus RNA and hepatitis B virus DNA shows a dynamic, complex replicative profile in chronic hepatitis B and D.

scientific article published on 5 March 2010

Quasispecies dynamics in main core epitopes of hepatitis B virus by ultra-deep-pyrosequencing

scientific article

Randomized prospective study evaluating tenofovir disoproxil fumarate prophylaxis against hepatitis B virus reactivation in anti-HBc-positive patients with rituximab-based regimens to treat hematologic malignancies: The Preblin study.

scientific article published on 12 September 2017

Randomized trial of peginterferon alfa-2b and ribavirin for 48 or 72 weeks in patients with hepatitis C virus genotype 1 and slow virologic response

scientific article published on October 2010

Rapid liver and spleen stiffness improvement in compensated advanced chronic liver disease patients treated with oral antivirals

scientific article

Redetection of HBV lamivudine-resistant mutations in a patient under entecavir therapy, who had been treated sequentially with nucleos(t)ide analogues

scientific article published in November 2007

Relevance of a full-length genomic RNA standard and a thermal-shock step for optimal hepatitis delta virus quantification

scientific article published on 2 July 2014

Reply to: "The importance of prognostic factors in cirrhosis".

scientific article published on 28 February 2014

Ribavirin therapy in chronic delta hepatitis.

scientific article published in September 1993

Role of screening in prevention and treatment.

scientific article

Safety and efficacy of an 8-week regimen of grazoprevir plus ruzasvir plus uprifosbuvir compared with grazoprevir plus elbasvir plus uprifosbuvir in participants without cirrhosis infected with hepatitis C virus genotypes 1, 2, or 3 (C-CREST-1 and C

scientific article published on 9 August 2017

Safety and efficacy of boceprevir/peginterferon/ribavirin for HCV G1 compensated cirrhotics: meta-analysis of 5 trials

scientific article

Serum hepatitis B core-related antigen is more accurate than hepatitis B surface antigen to identify inactive carriers, regardless of hepatitis B virus genotype

scientific article published on 10 March 2017

Severe anaemia related to oseltamivir during treatment of chronic hepatitis C: a new drug interaction? ⬇️

scientific article published on January 1, 2012

Sexual transmission of hepatitis C virus from a patient with chronic disease to his sex partner after removal of an intrauterine device

scientific article published in May 2003

Sofosbuvir and daclatasvir in mono- and HIV-coinfected patients with recurrent hepatitis C after liver transplant

article

Sofosbuvir and ribavirin in HCV genotypes 2 and 3.

scientific article published on 4 May 2014

Sporadic cases of acute autochthonous hepatitis E in Spain

scientific article published on July 2004

Study of hepatitis B virus replication and infection by other hepatitis viruses in patients with chronic hepatitis B virus infection

scientific article published in May 2002

Successful use of entecavir for a severe case of reactivation of hepatitis B virus following polychemotherapy containing rituximab

scientific article published on 30 July 2009

Tenofovir Alafenamide Fumarate: A New Tenofovir Prodrug for the Treatment of Chronic Hepatitis B Infection

scientific article

Tenofovir discontinuation after long-term viral suppression in HBeAg negative chronic hepatitis B. Can HBsAg levels be useful?

scientific article published on 8 May 2015

The development of low-grade cerebral edema in cirrhosis is supported by the evolution of (1)H-magnetic resonance abnormalities after liver transplantation.

scientific article

The renal effects of droxidopa are maintained in propranolol treated cirrhotic rats

scientific article published on 12 February 2014

The risk of hepatocellular carcinoma is decreasing after the first 5 years of entecavir or tenofovir in Caucasians with chronic hepatitis B.

scientific article published on 16 June 2017

The state of hepatitis B and C in the Mediterranean and Balkan countries: report from a summit conference.

scientific article published in August 2013

The value of quantiative detection of HBV-DNA amplified by PCR in the study of hepatitis B infection

scientific article published on 01 June 1996

Therapy for hepatitis C genotype 3: moving forward.

scientific article published on 13 May 2015

Therapy with direct-acting antivirals for genotype 3 patients: interferon's last gasp?

scientific article published on 25 September 2015

Thrombocytopenia associated with chronic liver disease

scientific article

Transient emergence of hepatitis B variants in a patient with chronic hepatitis B resistant to lamivudine ⬇️

scientific article published on March 1, 1998

Transmission of hepatitis B virus by transplantation of livers from donors positive for antibody to hepatitis B core antigen.

scientific article published in September 1999

Triple therapy for HCV genotype 1 infection: telaprevir or boceprevir? ⬇️

scientific article published on February 1, 2012

Triple therapy with boceprevir or telaprevir for treatment naïve HCV patients ⬇️

scientific article published on August 1, 2012

Twelve-week posttreatment follow-up to predict sustained virologic response for recurrent hepatitis C infection in liver recipients

scientific article published on February 2012

Tyrosine kinase inhibition ameliorates the hyperdynamic state and decreases nitric oxide production in cirrhotic rats with portal hypertension and ascites ⬇️

scientific article published on August 1, 1997

Ultra-deep pyrosequencing analysis of the hepatitis B virus preCore region and main catalytic motif of the viral polymerase in the same viral genome

scientific article published on 8 July 2011

Ultra-deep pyrosequencing detects conserved genomic sites and quantifies linkage of drug-resistant amino acid changes in the hepatitis B virus genome

scientific article

Use of the novel INNO-LiPA line probe assay for detection of hepatitis B virus variants that confer resistance to entecavir therapy

scientific article published on 3 December 2008

Usefulness of dried blood samples for quantification and molecular characterization of HBV-DNA.

scientific article published in July 2004

Usefulness of magnetic resonance spectroscopy for diagnosis of hepatic encephalopathy in a patient with relapsing confusional syndrome

scientific article published on November 1, 2001

Utility of week-4 viral response to tailor treatment duration in hepatitis C virus genotype 3/HIV co-infected patients

scientific article published in February 2007

Validity of the Spanish version of the Chronic Liver Disease Questionnaire (CLDQ) as a standard outcome for quality of life assessment

article

[Risk of transmission of HIV or hepatitis B or C viruses from an infected physician. Preventive measures]

scientific article published on 01 September 2007

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