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List of works by Lisa E. Gralinski

A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge ⬇️

scientific article published on September 21, 2011

A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice

scientific article published on 23 September 2020

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

scientific article published on 9 November 2015

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

scientific article published on 19 August 2020

A comprehensive collection of systems biology data characterizing the host response to viral infection.

scientific article

A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant

scientific article

A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures

scientific article published on 08 May 2020

A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

scientific article published on 27 August 2020

Acute SARS-CoV-2 Infection is Highly Cytopathic, Elicits a Robust Innate Immune Response and is Efficiently Prevented by EIDD-2801

scientific article published on 24 September 2020

Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice.

scientific article

An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19

scientific article published on 17 November 2020

Animal models for COVID-19

scientific article published on 23 September 2020

Annotation of long non-coding RNAs expressed in collaborative cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts

scientific article

Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity

scientific article published on 29 January 2014

Author Correction: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

scientific article published on 01 July 2020

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection

scientific article published on 21 September 2020

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.

scientific article

Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus

scientific article published on 30 April 2013

Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines

scholarly article by Vineet D. Menachery published in September 2018

Combination attenuation offers strategy for live-attenuated coronavirus vaccines

scholarly article published 28 April 2018

Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis

article

Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

scientific article published on 01 April 2020

Content and Performance of the MiniMUGA Genotyping Array, a New Tool To Improve Rigor and Reproducibility in Mouse Research

scientific article published on 16 October 2020

Contributions of E1A to mouse adenovirus type 1 pathogenesis following intranasal inoculation.

scientific article published on 7 September 2006

Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2

scientific article published on 31 October 2020

Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2

scientific article published on 12 August 2020

Erratum: Corrigendum: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

scientific article published on 01 April 2016

Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses

scientific article

Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice

scientific article published on February 2012

Genetic analysis of complex traits in the emerging Collaborative Cross

scientific article

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross

scientific article published on 9 October 2015

Genomic profiling of collaborative cross founder mice infected with respiratory viruses reveals novel transcripts and infection-related strain-specific gene and isoform expression

scientific article

Immune Predictors of Mortality After Ribonucleic Acid Virus Infection

scientific article published on 01 March 2020

Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection

scientific article published on 15 November 2011

MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis

scientific article published on 22 August 2017

MERS-CoV NSP16 necessary for IFN resistance and viral pathogenesis

MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape

scientific article published on 16 January 2018

Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury

scientific article published on 06 August 2013

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis

scientific article published on 15 November 2017

Modeling host genetic regulation of influenza pathogenesis in the collaborative cross

scientific article (publication date: February 2013)

Molecular pathology of emerging coronavirus infections

scientific article

Mouse adenovirus type 1 infection of natural killer cell-deficient mice

scientific article

Mouse adenovirus type 1-induced breakdown of the blood-brain barrier

scientific article

Mucin 4 Protects Female Mice from Coronavirus Pathogenesis

scientific article

Multi-omic network signatures of disease.

scientific article published on 07 January 2014

New Metrics for Evaluating Viral Respiratory Pathogenesis

scientific article published on 26 June 2015

Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses.

scientific article

Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody

scientific article published on 15 May 2020

Potently neutralizing and protective human antibodies against SARS-CoV-2

scientific article published on 15 July 2020

Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals

scientific article published on 22 May 2020

Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells

scientific article published on 30 January 2013

Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice

scientific article published on 07 July 2020

Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice

scientific article published on 28 April 2020

Research on HIV cure: Mapping the ethics landscape

scientific article

Return of the Coronavirus: 2019-nCoV

scientific article published on 24 January 2020

SARS-CoV-2 D614G Variant Exhibits Enhanced Replication ex vivo and Earlier Transmission in vivo

scientific article published on 29 September 2020

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

scientific article

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

scientific article published on 27 May 2020

SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801

scientific article

SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice

scientific article published in 2022

SARS-like WIV1-CoV poised for human emergence

scientific article published on 14 March 2016

Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice

scientific article

Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus

scientific article

The Mouse Universal Genotyping Array: From Substrains to Subspecies

scientific article published on 18 December 2015

The Role of EGFR in Influenza Pathogenicity: Multiple Network-Based Approaches to Identify a Key Regulator of Non-lethal Infections

scientific article published on 20 September 2019

The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus

scientific article

Transcriptional regulation of the mdm2 oncogene by p53 requires TRRAP acetyltransferase complexes

scientific article

Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection

scientific article published on 14 February 2020

Trypsin treatment unlocks barrier for zoonotic coronaviruses infection

scientific article published on 17 September 2019

Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling

scientific article

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