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Authors whose works are in public domain in at least one jurisdiction

List of works by Przemyslaw Grudnik

1-27 of 27 results

T cell Activation Is Driven by an ADP-Dependent Glucokinase Linking Enhanced Glycolysis with Mitochondrial Reactive Oxygen Species Generation

scientific article published on November 15, 2012

Protein targeting by the signal recognition particle.

scientific article

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)

scientific article (publication date: 24 May 2016)

Structural basis for the molecular evolution of SRP-GTPase activation by protein

scientific article

Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1.

scientific article published on 14 June 2017

Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2.

scientific article published in August 2017

Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells.

scientific article published on 7 August 2017

Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.

scientific article

Insights into eukaryotic Rubisco assembly - crystal structures of RbcX chaperones from Arabidopsis thaliana

scientific article

Crystal structure of a low molecular weight activator Blm-pep with yeast 20S proteasome - insights into the enzyme activation mechanism

scientific article published on 21 July 2017

Structural Basis of GD2 Ganglioside and Mimetic Peptide Recognition by 14G2a Antibody.

scientific article

A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction

scientific article

Investigation of Serine-Proteinase-Catalyzed Peptide Splicing in Analogues of Sunflower Trypsin Inhibitor 1 (SFTI-1)

scientific article

Crystal structure of ADP-dependent glucokinase from Methanocaldococcus jannaschii in complex with 5-iodotubercidin reveals phosphoryl transfer mechanism

scientific article published on 20 January 2018

Structural analysis of PIM1 kinase complexes with ATP-competitive inhibitors

scientific article published on 17 October 2017

Structural basis for ADP-dependent glucokinase inhibition by 8-bromo-substituted adenosine nucleotide

scientific article published on 21 May 2018

Crystal structure of the FAS1 domain of the hyaluronic acid receptor stabilin-2

scientific article published on 27 June 2018

Atomic resolution crystal structure of HV-BBI protease inhibitor from amphibian skin in complex with bovine trypsin

scientific article

Human and mouse PD-L1: similar molecular structure, but different druggability profiles

scientific article published on 22 January 2021

Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase

scientific article published on 30 March 2020

Chromosomal localization of PemIK toxin-antitoxin system results in the loss of toxicity - Characterization of pemIKSa1-Sp from Staphylococcus pseudintermedius

scientific article published on 21 June 2020

Macrocyclic Peptide Inhibitor of PD‐1/PD‐L1 Immune Checkpoint

scientific article published on 18 November 2020

Molecular basis for the bifunctional Uba4-Urm1 sulfur-relay system in tRNA thiolation and ubiquitin-like conjugation

scientific article published on 09 September 2020

Crystal Structure of Mannose Specific IIA Subunit of Phosphotransferase System from Streptococcus pneumoniae

scientific article published on 12 October 2020

Development of a novel, high-affinity ssDNA trypsin inhibitor

article

Crystal Structure of Kluyveromyces lactis Glucokinase (KlGlk1)

scientific article published on 28 September 2019

Structural Characterization of Glycerol Kinase from the Thermophilic Fungus Chaetomium thermophilum

scientific article published on 16 December 2020