List of works by Daniela Montesarchio

5‘-Modified G-Quadruplex Forming Oligonucleotides Endowed with Anti-HIV Activity: Synthesis and Biophysical Properties

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A first-in-class and a fished out anticancer platinum compound: cis-[PtCl2(NH3)2] and cis-[PtI2(NH3)2] compared for their reactivity towards DNA model systems

scientific article

A new competitive fluorescence assay for the detection of patulin toxin

scientific article published on 01 January 2007

A new design for nucleolipid-based Ru(III) complexes as anticancer agents

scientific article

A new solid-phase synthesis of oligonucleotides 3'-conjugated with peptides

scientific article published on 01 February 1999

An efficient and versatile solid-phase synthesis of 5'- and 3'-conjugated oligonucleotides

scientific article published on 01 October 2005

An efficient solid phase synthesis of 5'-phosphodiester and phosphoramidate monoester nucleoside analogues.

scientific article

An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies.

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Anti-HIV activity of new higher order G-quadruplex aptamers obtained from tetra-end-linked oligonucleotides.

scientific article published on 15 March 2018

Anti-VEGF DNA-based aptamers in cancer therapeutics and diagnostics

scientific article published on 10 October 2020

Anticancer Ruthenium(III) Complexes and Ru(III)-Containing Nanoformulations: An Update on the Mechanism of Action and Biological Activity

scientific article published on 26 September 2019

Anticancer cationic ruthenium nanovectors: from rational molecular design to cellular uptake and bioactivity.

scientific article

Antiproliferative effects of ruthenium-based nucleolipidic nanoaggregates in human models of breast cancer in vitro: insights into their mode of action.

scientific article published on 28 March 2017

Antitumour activity of resveratrol on human melanoma cells: A possible mechanism related to its interaction with malignant cell telomerase.

scientific article published on 2 August 2017

Automated solid phase synthesis of cyclic oligonucleotides: a further improvement

scientific article published on 01 October 1995

Benzodifuran Derivatives as Potential Antiproliferative Agents: Possible Correlation between Their Bioactivity and Aggregation Properties

scientific article published on 29 November 2016

Benzodifurans for biomedical applications: BZ4, a selective anti-proliferative and anti-amyloid lead compound

scientific article published on 25 February 2019

Breast Cancer Chemotherapeutic Options: A General Overview on the Preclinical Validation of a Multi-Target Ruthenium(III) Complex Lodged in Nucleolipid Nanosystems

scientific article published on 05 June 2020

Carbohydrate-based synthetic ion transporters.

scientific article

Controlled Pore Glass-based oligonucleotide affinity support: towards High Throughput Screening methods for the identification of conformation-selective G-quadruplex ligands

scientific article published on 03 May 2018

Cyclic Phosphate-Linked Oligosaccharides: Synthesis and Conformational Behavior of Novel Cyclic Oligosaccharide Analogues

scientific article published on 01 April 2006

Design, Synthesis and Characterization of Cyclic NU172 Analogues: A Biophysical and Biological Insight

scientific article published on 29 May 2020

Design, synthesis and characterisation of guanosine-based amphiphiles.

scientific article

Developing functionalized Fe3O4–Au nanoparticles: a physico-chemical insight

scientific article published in 2015

Dimeric and Multimeric DNA Aptamers for Highly Effective Protein Recognition

scientific article published on 10 November 2020

Discovery of novel anti-HIV active G-quadruplex-forming oligonucleotides.

scientific article

Effect of lengthening of peptide backbone by insertion of chiral beta-homo amino acid residues: conformational behavior of linear peptides containing alternating L-leucine and beta-homo L-leucine residues

scientific article published on 01 February 2000

Elucidating the reactivity of Pt(II) complexes with (O,S) bidentate ligands towards DNA model systems.

scientific article

Exploring cellular uptake, accumulation and mechanism of action of a cationic Ru-based nanosystem in human preclinical models of breast cancer

scientific article published on 07 May 2019

Fluorescence Sensing Using DNA Aptamers in Cancer Research and Clinical Diagnostics.

scientific article published on 20 December 2017

Fluorescence enhancement upon G-quadruplex folding: synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer.

scientific article published on 25 October 2013

Fluorescent thrombin binding aptamer-tagged nanoparticles for an efficient and reversible control of thrombin activity

scientific article

G-Quadruplex Forming Oligonucleotides as Anti-HIV Agents

scientific article published on 22 September 2015

G-Quadruplex on Oligo Affinity Support (G4-OAS): An Easy Affinity Chromatography-Based Assay for the Screening of G-Quadruplex Ligands

scientific article published on 14 April 2014

G-quadruplex nucleic acids.

scientific article published on 10 August 2010

G-quadruplex-based aptamers against protein targets in therapy and diagnostics.

scientific article

Guanine-based amphiphiles: synthesis, ion transport properties and biological activity.

scientific article published on 14 January 2015

Huntingtin protein: A new option for fixing the Huntington's disease countdown clock.

scientific article published on 8 March 2018

Insights into the G-rich VEGF-binding aptamer V7t1: when two G-quadruplexes are better than one!

scientific article published on 01 September 2019

Interaction of anticancer Ru(III) complexes with single stranded and duplex DNA model systems.

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Investigating the ruthenium metalation of proteins: X-ray structure and Raman microspectroscopy of the complex between RNase A and AziRu

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Ionophores at work: Exploring the interaction of guanosine-based amphiphiles with phospholipid membranes.

scientific article published on 7 September 2017

N(3)-protection of thymidine with Boc for an easy synthetic access to sugar-alkylated nucleoside analogs

scientific article published on 01 March 2012

Nanostructuring of CyPLOS (Cyclic Phosphate-Linked OligoSaccharides), novel saccharide-based synthetic ion transporters

scientific article published on 02 November 2010

New solid supports linking nucleoside scaffolds.

scientific article published in May 2003

Not unusual, just different! Chemistry, biology and applications of G-quadruplex nucleic acids

scientific article published on 01 May 2017

Novel amphiphilic cyclic oligosaccharides: synthesis and self-aggregation properties.

scientific article published on 8 November 2007

Nucleolipid nanovectors as molecular carriers for potential applications in drug delivery.

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Oligonucleotides containing a lysine residue as 3'-3' junction for alternate strand triple helix formation.

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On the interaction of an anticancer trisubstituted naphthalene diimide with G-quadruplexes of different topologies: a structural insight

scientific article published on 10 November 2020

On the mechanism of ion transport through lipid membranes mediated by PEGylated cyclic oligosaccharides (CyPLOS): an ESR study.

scientific article published on 26 May 2013

On the pH-Modulated Ru-Based Prodrug Activation Mechanism

scientific article published on 07 January 2019

Phosphocholine-decorated superparamagnetic iron oxide nanoparticles: defining the structure and probing in vivo applications.

scientific article published on 11 January 2016

Polyvalent nucleic acid aptamers and modulation of their activity: a focus on the thrombin binding aptamer.

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Ruthenium-based complex nanocarriers for cancer therapy.

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Solid-phase synthesis of cyclic PNA and PNA-DNA chimeras

scientific article published on 01 May 2006

Stability Is Not Everything: The Case of the Cyclisation of a Thrombin-Binding Aptamer

scientific article published on 14 May 2019

Synthesis and DNA binding properties of DNA-PNA chimeras.

scientific article published on May 2003

Synthesis and biophysical characterization of G-rich oligonucleotides conjugated with sugar-phosphate tails.

scientific article published in January 2007

Synthesis and preliminary biological evaluation of a new pyridocarbazole derivative covalently linked to a thymidine nucleoside as a potential targeted antitumoral agent. I.

scientific article published in August 2003

Synthesis of a cholesteryl-HEG phosphoramidite derivative and its application to lipid-conjugates of the anti-HIV 5'TGGGAG³' Hotoda's sequence.

scientific article

Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes

scientific article published on 30 September 2020

Synthesis, biophysical characterization, and anti-HIV activity of glyco-conjugated G-quadruplex-forming oligonucleotides.

scientific article published on 7 February 2008

Synthesis, self-aggregation and bioactivity properties of a cationic aminoacyl surfactant, based on a new class of highly functionalized nucleolipids.

scientific article

Tailoring a lead-like compound targeting multiple G-quadruplex structures

scientific article published on 27 November 2018

Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.

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Targeting duplex DNA with DNA-PNA chimeras? Physico-chemical characterization of a triplex DNA-PNA/DNA/DNA.

scientific article published on March 2004

The role of G-quadruplex structures of LIGS-generated aptamers R1.2 and R1.3 in IgM specific recognition

scientific article published on 22 April 2019

Trifunctionalized Naphthalene Diimides and Dimeric Analogues as G-Quadruplex-Targeting Anticancer Agents Selected by Affinity Chromatography

scientific article published on 13 March 2020

Tuning the Polymorphism of the Anti-VEGF G-rich V7t1 Aptamer by Covalent Dimeric Constructs

scientific article published on 13 March 2020

“Dressing up” an Old Drug: An Aminoacyl Lipid for the Functionalization of Ru(III)-Based Anticancer Agents

scientific article published on 11 December 2017