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List of works by Hans-Gottfried Genieser

(Rp)- and (Sp)-8-piperidino-adenosine 3',5'-(cyclic)thiophosphates discriminate completely between site A and B of the regulatory subunits of cAMP-dependent protein kinase type I and II

scientific article published on 01 May 1994

(Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor.

scientific article published on October 1994

8-pCPT-2'-O-Me-cAMP-AM: an improved Epac-selective cAMP analogue.

scientific article

A chemical proteomics approach to identify c-di-GMP binding proteins in Pseudomonas aeruginosa

article by Juliane Düvel et al published February 2012 in Journal of Microbiological Methods

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

scientific article

Activation of PDE10 and PDE11 Phosphodiesterases ⬇️

scientific article published on November 21, 2011

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

scientific article published on December 2010

Activation of cGMP-dependent protein kinase Iα and cAMP-dependent protein kinase A isoforms by cyclic nucleotides.

scientific article published in August 2011

Activation of protein kinase A (PKA) by 8-Cl-cAMP as a novel approach for antileukaemic therapy.

scientific article published in July 2004

Activation profile of cGMP-dependent protein kinase Iα

scientific article published on 29 August 2013

Analysis of substrate specificity and kinetics of cyclic nucleotide phosphodiesterases with N'-methylanthraniloyl-substituted purine and pyrimidine 3',5'-cyclic nucleotides by fluorescence spectrometry

scientific article published in 2013

Application of Synthetic Peptide Arrays To Uncover Cyclic Di-GMP Binding Motifs

scientific article published on 31 August 2015

Binding of Regulatory Subunits of Cyclic AMP-Dependent Protein Kinase to Cyclic CMP Agarose ⬇️

scientific article (publication date: 2012)

Bioactivatable, Membrane-Permeant Analogs of Cyclic Nucleotides as Biological Tools for Growth Control of C6 Glioma Cells ⬇️

scientific article published on September 1, 2003

Biochemical characterization and cellular imaging of a novel, membrane permeable fluorescent cAMP analog

scientific article

CREB phosphorylation and melatonin biosynthesis in the rat pineal gland: Involvement of cyclic AMP dependent protein kinase type II

scientific article published on 01 October 1999

Chemical tools selectively target components of the PKA system

scientific article published on 12 February 2009

Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration.

scientific article published on 12 March 2018

Cyclic AMP induces IPC leukemia cell apoptosis via CRE-and CDK-dependent Bim transcription

scientific journal article

Cyclic CMP and cyclic UMP: new (old) second messengers.

scientific article published in August 2011

Cyclic nucleotide analogs as probes of signaling pathways.

scientific article

Cyclic nucleotides as affinity tools: phosphorothioate cAMP analogues address specific PKA subproteomes.

scientific article

DNA catabolites in triathletes: effects of supplementation with an aronia–citrus juice (polyphenols-rich juice)

scientific article published on 01 April 2016

Derivatives of 1-beta-D-ribofuranosylbenzimidazole 3',5'-phosphate that mimic the actions of adenosine 3',5'-phosphate (cAMP) and guanosine 3',5'-phosphate (cGMP)

scientific article published on 01 October 1992

Effect of cGMP analogues and protein kinase G blocker on secretory activity, apoptosis and the cAMP/protein kinase A system in porcine ovarian granulosa cells in vitro

scientific article published on 01 September 2000

Effect of elite physical exercise by triathletes on seven catabolites of DNA oxidation

scientific article published on 8 April 2015

Effect of four cGMP analogues with different mechanisms of action on hormone release by porcine ovarian granulosa cells in vitro.

scientific article published in January 2000

Effect of restricted food intake on production, catabolism, and effects of IGF-I and cyclic nucleotides in cultured ovarian tissue of domestic nutria (Myocastor coypus).

scientific article

Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.

scientific article

Facilitation of ß-cell K(ATP) channel sulfonylurea sensitivity by a cAMP analog selective for the cAMP-regulated guanine nucleotide exchange factor Epac.

scientific article published on March 2010

Fast-atom bombardment tandem mass spectrometry of cyclic nucleotide analogues used as site-selective activators of cyclic nucleotide-dependent protein kinases

scientific article published on 01 January 1998

Glucose-dependent potentiation of mouse islet insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM.

scientific article published on November 2009

Kinetics and nucleotide specificity of a surface cAMP binding site in , which is not down-regulated by cAMP

scientific article published on 15 July 1991

Mapping of the epitope/paratope interactions of a monoclonal antibody directed against adenosine 3',5'-monophosphate ⬇️

scientific article published on July 1, 1992

Medicinal Chemistry of the Noncanonical Cyclic Nucleotides cCMP and cUMP.

scientific article published on 29 November 2016

Melatonin and hydroxytyrosol-rich wines influence the generation of DNA oxidation catabolites linked to mutagenesis after the ingestion of three types of wine by healthy volunteers.

scientific article published on 24 November 2016

Membrane-permeant derivatives of cyclic AMP optimized for high potency, prolonged activity, or rapid reversibility.

scientific article published on October 1994

Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells.

scientific article published on 19 July 2011

New cGMP analogues restrain proliferation and migration of melanoma cells.

scientific article published on 25 December 2017

New dimeric cGMP analogues reduce proliferation in three colon cancer cell lines

scientific article

Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans ⬇️

scientific article published on May 1, 2011

Preparations of Rp-cyclic adenosine 3',5'-phosphorothioate (Rp-cAMPS) can contain biologically active amounts of adenosine.

scientific article published in March 1993

Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates.

scientific article published on June 1990

Quantification of cAMP and cGMP analogs in intact cells: pitfalls in enzyme immunoassays for cyclic nucleotides ⬇️

scientific article published on June 29, 2011

Quantification of cAMP and cGMP analogs in intact cells: pitfals in enzyme immunoassays for cyclic nucleotides.

scientific article published in August 2011

Regulation of olfactory signalling via cGMP-dependent protein kinase

scientific article published on 01 March 1996

Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes

scientific journal article

Starfish oocyte maturation: evidence for a cyclic AMP-dependent inhibitory pathway

scientific article published on 01 May 1989

Stimulation of proglucagon gene expression by human GPR119 in enteroendocrine L-cell line GLUTag.

scientific article published on 24 June 2013

Structure-guided design of selective Epac1 and Epac2 agonists

scientific article

Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel ⬇️

scientific article published on February 1, 1998

Systematic interpretation of cyclic nucleotide binding studies using KinetXBase

scientific article published in March 2008

The Chemistry of the Noncanonical Cyclic Dinucleotide 2'3'-cGAMP and Its Analogs.

scientific article

Unhydrolyzable analogues of adenosine 3':5'-monophosphate demonstrating growth inhibition and differentiation in human cancer cells ⬇️

scientific article published on May 1, 1992

cAMP signaling regulates histone H3 phosphorylation and mitotic entry through a disruption of G2 progression.

scientific article published on 8 July 2008

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