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List of works by Jérôme Giustiniani

A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor ⬇️

scientific article

A soluble form of the MHC class I-specific CD160 receptor is released from human activated NK lymphocytes and inhibits cell-mediated cytotoxicity

scientific article

Anti-CD160, Alone or in Combination With Bevacizumab, Is a Potent Inhibitor of Ocular Neovascularization in Rabbit and Monkey Models

scientific article published on 01 June 2018

Autophagy is decreased in triple-negative breast carcinoma involving likely the MUC1-EGFR-NEU1 signalling pathway.

scientific article published in May 2015

CD160 Expression in Retinal Vessels Is Associated With Retinal Neovascular Diseases

scientific article published on 01 June 2018

CD160 signaling mediates PI3K-dependent survival and growth signals in chronic lymphocytic leukemia.

scientific article published on 17 February 2010

CD160: a unique activating NK cell receptor

scientific article published on 13 February 2011

Chemotherapy treatment induces an increase of autophagy in the luminal breast cancer cell MCF7, but not in the triple-negative MDA-MB231.

scientific article

Corrigendum: Minimizing the risk of allo-sensitization to optimize the benefit of allogeneic cardiac-derived stem/progenitor cells.

scientific article published on 16 March 2017

Corrigendum: Minimizing the risk of allo-sensitization to optimize the benefit of allogeneic cardiac-derived stem/progenitor cells.

scientific article published on 20 October 2017

Differential and tumor-specific expression of CD160 in B-cell malignancies ⬇️

scientific article published on June 28, 2011

Engagement of CD160 receptor by HLA-C is a triggering mechanism used by circulating natural killer (NK) cells to mediate cytotoxicity.

scientific article

Engagement of IL-1 receptor accessory protein (IL-1RAcP) with the monoclonal antibody AY19 provides co-activating signals and prolongs the CD2-induced proliferation of peripheral blood lymphocytes.

scientific article published on 11 May 2011

Human and mouse mast cells express and secrete the GPI-anchored isoform of CD160.

scientific article published on 30 December 2010

IL-17A and its homologs IL-25/IL-17E recruit the c-RAF/S6 kinase pathway and the generation of pro-oncogenic LMW-E in breast cancer cells

scientific article

IL-17A is produced by breast cancer TILs and promotes chemoresistance and proliferation through ERK1/2.

scientific article published on 09 December 2013

IL-17E synergizes with EGF and confers in vitro resistance to EGFR-targeted therapies in TNBC cells

scientific article published on 23 July 2016

Identification of CD245 as myosin 18A, a receptor for surfactant A: A novel pathway for activating human NK lymphocytes

scientific article published on 13 January 2016

Identification of a novel CD160+ CD4+ T-lymphocyte subset in the skin: a possible role for CD160 in skin inflammation

scientific article

Inhibition of CD39 enzymatic function at the surface of tumor cells alleviates their immunosuppressive activity

scientific article

Integrating longitudinal serum IL-17 and IL-23 follow-up, along with autoantibodies variation, contributes to predict bullous pemphigoid outcome

scientific article

Minimal residual disease detection with tumor-specific CD160 correlates with event-free survival in chronic lymphocytic leukemia.

scientific article

Minimizing the risk of allo-sensitization to optimize the benefit of allogeneic cardiac-derived stem/progenitor cells.

scientific article published on 24 January 2017

Possible Pathogenic Role of the Transmembrane Isoform of CD160 NK Lymphocyte Receptor in Paroxysmal Nocturnal Hemoglobinuria ⬇️

scientific article published on February 1, 2012

Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells

scientific article published on 29 June 2006

Targeting the Tumor Microenvironment: The Protumor Effects of IL-17 Related to Cancer Type

scientific article

The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway.

scientific article published on 6 December 2017

The co-expression of 2B4 (CD244) and CD160 delineates a subpopulation of human CD8+ T cells with a potent CD160-mediated cytolytic effector function

scientific article published on 01 September 2006

[A novel VEGF-independent antiangiogenic therapy targeting the CD160 receptor]

scientific article published on 27 January 2012

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