List of works - Juan R Rodriguez-Madoz

A novel system for the production of high levels of functional human therapeutic proteins in stable cells with a Semliki Forest virus noncytopathic vector.

scientific article

A quick and efficient method to generate mammalian stable cell lines based on a novel inducible alphavirus DNA/RNA layered system.

scientific article published on 3 May 2014

Biodistribution and tumor infectivity of semliki forest virus vectors in mice: effects of re-administration.

scientific article

CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I

scientific article published in Nature Communications

Cryopreservation of microencapsulated murine mesenchymal stem cells genetically engineered to secrete erythropoietin.

scientific article published on 20 February 2015

DENV inhibits type I IFN production in infected cells by cleaving human STING

scientific article published on 4 October 2012

Dengue virus inhibits the production of type I interferon in primary human dendritic cells

scientific article published on 17 February 2010

Development of a new noncytopathic Semliki Forest virus vector providing high expression levels and stability.

scientific article

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

scientific article

Generation and characterization of human iPSC line generated from mesenchymal stem cells derived from adipose tissue.

scientific article published on 2 December 2015

Generation and characterization of human iPSC lines derived from a Primary Hyperoxaluria Type I patient with p.I244T mutation.

scientific article published on 28 December 2015

Generation of Macaca fascicularis iPS cell line ATCi-MF1 from adult skin fibroblasts using non-integrative Sendai viruses

scientific article

Increased efficacy and safety in the treatment of experimental liver cancer with a novel adenovirus-alphavirus hybrid vector.

scientific article published on February 2006

Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex

scientific article

Long-Term PEDF Release in Rat Iris and Retinal Epithelial Cells after Sleeping Beauty Transposon-Mediated Gene Delivery.

scientific article published on 12 August 2017

Neuregulin-1β induces mature ventricular cardiac differentiation from induced pluripotent stem cells contributing to cardiac tissue repair

scientific article

Preclinical Evaluation of a Cell-Based Gene Therapy Using the Sleeping Beauty Transposon System in Choroidal Neovascularization

scientific article published on 09 November 2019

Recombinant influenza A viruses with enhanced levels of PB1 and PA viral protein expression

scientific article published on 7 March 2012

Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome.

scientific article published on 27 December 2017

Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma.

scientific article published on 09 September 2009

Short-term intratumoral interleukin-12 expressed from an alphaviral vector is sufficient to induce an efficient antitumoral response against spontaneous hepatocellular carcinomas.

scientific article published on 7 January 2014

SimiC enables the inference of complex gene regulatory dynamics across cell phenotypes

scientific article published in 2022

Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12.

scientific article published on 19 December 2014

Treatment of chronic viral hepatitis in woodchucks by prolonged intrahepatic expression of interleukin-12.

scientific article published on 30 December 2008

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.

scientific article

List of works by Juan R Rodriguez-Madoz

A novel system for the production of high levels of functional human therapeutic proteins in stable cells with a Semliki Forest virus noncytopathic vector.

A quick and efficient method to generate mammalian stable cell lines based on a novel inducible alphavirus DNA/RNA layered system.

Biodistribution and tumor infectivity of semliki forest virus vectors in mice: effects of re-administration.

CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I

Cryopreservation of microencapsulated murine mesenchymal stem cells genetically engineered to secrete erythropoietin.

DENV inhibits type I IFN production in infected cells by cleaving human STING

Dengue virus inhibits the production of type I interferon in primary human dendritic cells

Development of a new noncytopathic Semliki Forest virus vector providing high expression levels and stability.

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

Generation and characterization of human iPSC line generated from mesenchymal stem cells derived from adipose tissue.

Generation and characterization of human iPSC lines derived from a Primary Hyperoxaluria Type I patient with p.I244T mutation.

Generation of Macaca fascicularis iPS cell line ATCi-MF1 from adult skin fibroblasts using non-integrative Sendai viruses

Increased efficacy and safety in the treatment of experimental liver cancer with a novel adenovirus-alphavirus hybrid vector.

Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex

Long-Term PEDF Release in Rat Iris and Retinal Epithelial Cells after Sleeping Beauty Transposon-Mediated Gene Delivery.

Neuregulin-1β induces mature ventricular cardiac differentiation from induced pluripotent stem cells contributing to cardiac tissue repair

Preclinical Evaluation of a Cell-Based Gene Therapy Using the Sleeping Beauty Transposon System in Choroidal Neovascularization

Recombinant influenza A viruses with enhanced levels of PB1 and PA viral protein expression

Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome.

Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma.

Short-term intratumoral interleukin-12 expressed from an alphaviral vector is sufficient to induce an efficient antitumoral response against spontaneous hepatocellular carcinomas.

SimiC enables the inference of complex gene regulatory dynamics across cell phenotypes

Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12.

Treatment of chronic viral hepatitis in woodchucks by prolonged intrahepatic expression of interleukin-12.

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.