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List of works by Laurent Kremer

1H-1,2,3-Triazole-Tethered Isatin–Ferrocene and Isatin–Ferrocenylchalcone Conjugates: Synthesis and in Vitro Antitubercular Evaluation

1H-1,2,3-triazole-tethered uracil-ferrocene and uracil-ferrocenylchalcone conjugates: Synthesis and antitubercular evaluation

scientific article published on 12 November 2016

1H-Benzo[d]Imidazole Derivatives Affect MmpL3 in Mycobacterium tuberculosis

scientific article published on 23 September 2019

4-Aminoquinoline-β-lactam conjugates: synthesis, antimalarial, and antitubercular evaluation

scientific article

7 Antibiotics and New Inhibitors of the Cell Wall

7-chloroquinoline-isatin conjugates: antimalarial, antitubercular, and cytotoxic evaluation

scientific article published on 14 March 2014

A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos

scientific article

A Simple and Rapid Gene Disruption Strategy in Mycobacterium abscessus: On the Design and Application of Glycopeptidolipid Mutants

scientific article published on 14 March 2018

A new dehydratase conferring innate resistance to thiacetazone and intra-amoebal survival of Mycobacterium smegmatis

scientific article

A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus.

scientific article

A piperidinol-containing molecule is active against Mycobacterium tuberculosis by inhibiting the mycolic acid flippase activity of MmpL3

scientific article published on 27 September 2019

A unique PE_PGRS protein inhibiting host cell cytosolic defenses and sustaining full virulence of Mycobacterium marinum in multiple hosts

scientific article published on 28 April 2016

A zebrafish model of Mycobacterium kansasii infection reveals large extracellular cord formation

scientific article published on 17 April 2020

AccD6, a key carboxyltransferase essential for mycolic acid synthesis in Mycobacterium tuberculosis, is dispensable in a nonpathogenic strain

scientific article published on 7 October 2011

Acetic Acid, the active component of vinegar, is an effective tuberculocidal disinfectant

scientific article (publication date: 25 February 2014)

Acid-Fast Positive and Acid-Fast Negative Mycobacterium tuberculosis: The Koch Paradox.

scientific article published on March 2017

Active Benzimidazole Derivatives Targeting the MmpL3 Transporter in Mycobacterium abscessus

scientific article published on 07 January 2020

Alkylated/aminated nitroimidazoles and nitroimidazole-7-chloroquinoline conjugates: Synthesis and anti-mycobacterial evaluation

scientific article published on 08 March 2018

Altered NADH/NAD+ ratio mediates coresistance to isoniazid and ethionamide in mycobacteria.

scientific article published on February 2005

An FHA phosphoprotein recognition domain mediates protein EmbR phosphorylation by PknH, a Ser/Thr protein kinase from Mycobacterium tuberculosis

scientific journal article

An improved method to unravel phosphoacceptors in Ser/Thr protein kinase-phosphorylated substrates

scientific journal article

Antimycobacterial Activity and Mechanism of Action of NAS-91

scientific article

Antitubercular activity of disulfiram, an antialcoholism drug, against multidrug- and extensively drug-resistant Mycobacterium tuberculosis isolates

scientific article

Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis

scientific article published on 16 June 2013

Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea.

scientific article published on 26 September 2016

Azide-alkyne cycloaddition en route to 4-aminoquinoline-ferrocenylchalcone conjugates: synthesis and anti-TB evaluation.

scientific article

Azide–alkynecycloadditionen route towards 1H-1,2,3-triazole-tethered β-lactam–ferrocene and β-lactam–ferrocenylchalcone conjugates: synthesis and in vitro anti-tubercular evaluation

scientific article published on 29 October 2012

B cells response directed against Cut4 and CFP21 lipolytic enzymes in active and latent tuberculosis infections.

scientific article

Base-Promoted Expedient Access to Spiroisatins: Synthesis and Antitubercular Evaluation of 1H-1,2,3-Triazole-Tethered Spiroisatin–Ferrocene and Isatin–Ferrocene Conjugates

Bedaquiline inhibits the ATP synthase in Mycobacterium abscessus and is effective in infected zebrafish

scientific article published on 14 August 2017

Binding of NADP+ triggers an open-to-closed transition in a mycobacterial FabG β-ketoacyl-ACP reductase

scientific article published on 26 January 2017

CR3-dependent negative regulation of human eosinophils by Mycobacterium bovis BCG lipoarabinomannan

scientific article published on 25 February 2012

Characterization of a mycobacterial cellulase and its impact on biofilm- and drug-induced cellulose production

scientific article

Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis

scientific article published in May 2002

Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis.

scientific article published on November 2005

Controlling Extra- and Intramacrophagic Mycobacterium abscessus by Targeting Mycolic Acid Transport

scientific article

Corrigendum to “Synthesis and in vitro antitubercular activity of ferrocene-based hydrazones” [Bioorg. Med. Chem. Lett. 21 (2011) 2866–2868]

scholarly article by Aman Mahajan et al published June 2011 in Bioorganic & Medicinal Chemistry Letters

Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus

scientific article published on 12 July 2019

Crystallization and preliminary X-ray diffraction data of Mycobacterium tuberculosis FbpC1 (Rv3803c).

scientific article

Current perspectives on the families of glycoside hydrolases of Mycobacterium tuberculosis: their importance and prospects for assigning function to unknowns

scientific article

Cyclipostins and Cyclophostin Analogues as Multitarget Inhibitors That Impair Growth of Mycobacterium abscessus

scientific article published on 25 July 2019

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis.

scientific article published on 18 September 2017

Cyclipostins and Cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo.

scientific article published on 4 January 2018

Cyclophostin and cyclipostins analogs, new promising molecules to treat mycobacterial-related diseases

scientific article published on 11 December 2017

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos

scientific article published on 9 September 2015

Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent

scientific article published on 06 July 2016

Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice

scientific journal article

Delineating the Physiological Roles of the PE and Catalytic Domains of LipY in Lipid Consumption in Mycobacterium-Infected Foamy Macrophages

scientific article published on 22 August 2018

Design, synthesis and docking studies of some novel (R)-2-(4'-chlorophenyl)-3-(4'-nitrophenyl)-1,2,3,5-tetrahydrobenzo[4,5] imidazo [1,2-c]pyrimidin-4-ol derivatives as antitubercular agents

scientific article published on 11 June 2014

Design, synthesis, anti-mycobacterial and cytotoxic evaluation of C-4 functionalized 1,8-naphthalimide-heterocyclic hydrazide conjugates

scientific article published on 07 March 2019

Detection of Mycobacterium tuberculosis in paucibacillary sputum: performances of the Xpert MTB/RIF ultra compared to the Xpert MTB/RIF, and IS6110 PCR

scientific article published on 21 February 2019

Dissecting erm(41)-Mediated Macrolide-Inducible Resistance in Mycobacterium abscessus

scientific article published on 27 January 2020

Dissecting the membrane lipid binding properties and lipase activity of Mycobacterium tuberculosis LipY domains

scientific article published on 16 May 2019

Division and cell envelope regulation by Ser/Thr phosphorylation: Mycobacterium shows the way.

scientific article published on March 2010

Dry-Powder Inhaler Formulation of Rifampicin: An Improved Targeted Delivery System for Alveolar Tuberculosis

scientific article published on 16 May 2017

Dual inhibition of mycobacterial fatty acid biosynthesis and degradation by 2-alkynoic acids

scientific article published on 01 March 2006

Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism

scientific article

Efficacy and Mode of Action of a Direct Inhibitor of Mycobacterium abscessus InhA

scientific article published on 15 September 2022

Efficacy of bedaquiline, alone or in combination with imipenem, against Mycobacterium abscessus in C3HeB/FeJ mice

scientific article published on 06 April 2020

EmbR2, a structural homologue of EmbR, inhibits the Mycobacterium tuberculosis kinase/substrate pair PknH/EmbR

scientific journal article

Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acids during mycobacterial growth in biofilms

scientific article

EthA, a common activator of thiocarbamide-containing drugs acting on different mycobacterial targets

scientific journal article

Experimental Models of Foamy Macrophages and Approaches for Dissecting the Mechanisms of Lipid Accumulation and Consumption during Dormancy and Reactivation of Tuberculosis

scientific article

Exposure of mycobacteria to cell wall-inhibitory drugs decreases production of arabinoglycerolipid related to Mycolyl-arabinogalactan-peptidoglycan metabolism

scientific article published on 7 February 2012

Exposure to a cutinase-like serine esterase triggers rapid lysis of multiple mycobacterial species

scientific article

Expression of OmpATb is dependent on small membrane proteins in Mycobacterium bovis BCG.

scientific article published on 28 July 2011

Expression, purification and characterisation of soluble GlfT and the identification of a novel galactofuranosyltransferase Rv3782 involved in priming GlfT-mediated galactan polymerisation in Mycobacterium tuberculosis

scientific journal article

FTY720 controls disease severity and attenuates sciatic nerve damage in chronic experimental autoimmune neuritis

scholarly article by Laurent Kremer et al published 2 March 2019 in Journal of Neuroinflammation

Fast chemical force microscopy demonstrates that glycopeptidolipids define nanodomains of varying hydrophobicity on mycobacteria

scientific article published on 21 April 2020

Fatty acyl chains of Mycobacterium marinum lipooligosaccharides: structure, localization and acylation by PapA4 (MMAR_2343) protein

scientific article

From the characterization of the four serine/threonine protein kinases (PknA/B/G/L) of Corynebacterium glutamicum toward the role of PknA and PknB in cell division

scientific journal article

From the characterization of the four serine/threonine protein kinases (PknA/B/G/L) of Corynebacterium glutamicum toward the role of PknA and PknB inn cell division.

scientific article published in June 2009

Functional Characterization of the N-Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus

scientific article published on 04 November 2020

Functional role of the PE domain and immunogenicity of the Mycobacterium tuberculosis triacylglycerol hydrolase LipY.

scientific article

Glycopeptidolipids, a Double-Edged Sword of the Mycobacterium abscessus Complex.

scientific article published on 5 June 2018

GroEL1: a dedicated chaperone involved in mycolic acid biosynthesis during biofilm formation in mycobacteria.

scientific article published in December 2005

Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria.

scientific article published on 05 May 2008

Identification and characterisation of small-molecule inhibitors of Rv3097c-encoded lipase (LipY) of Mycobacterium tuberculosis that selectively inhibit growth of bacilli in hypoxia.

scientific article published on 14 May 2013

Identification and structural characterization of an unusual mycobacterial monomeromycolyl-diacylglycerol

scientific article published in August 2005

Identification by surface plasmon resonance of the mycobacterial lipomannan and lipoarabinomannan domains involved in binding to CD14 and LPS-binding protein

scientific article published on 02 March 2007

Identification of KasA as the cellular target of an anti-tubercular scaffold

scientific article

Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus.

scientific article published on 17 January 2018

Identification of inhibitors targeting Mycobacterium tuberculosis cell wall biosynthesis via dynamic combinatorial chemistry

scientific article published on 14 September 2017

Identification of the Mycobacterium marinum Apa antigen O-mannosylation sites reveals important glycosylation variability with the M. tuberculosis Apa homologue

scientific article published on 22 July 2012

Immune response induced by recombinant Mycobacterium bovis BCG producing the cholera toxin B subunit.

scientific article

Immunoregulatory functions of interleukin 18 and its role in defense against bacterial pathogens

scientific article (publication date: March 2002)

In vitro evaluation of a new drug combination against clinical isolates belonging to the Mycobacterium abscessus complex

scientific article published on 3 October 2014

In vivo assessment of drug efficacy against Mycobacterium abscessus using the embryonic zebrafish test system.

scientific article

Increased phagocytosis of Mycobacterium marinum mutants defective in lipooligosaccharide production: a structure-activity relationship study

scientific article

Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria

scientific article published on 24 March 2003

Inhibition of the β-Lactamase BlaMab by Avibactam Improves the In Vitro and In Vivo Efficacy of Imipenem against Mycobacterium abscessus

scientific article published on 17 January 2017

Insights into the smooth-to-rough transitioning in Mycobacterium bolletii unravels a functional Tyr residue conserved in all mycobacterial MmpL family members.

scientific article published on 20 November 2015

Keto-mycolic acid-dependent pellicle formation confers tolerance to drug-sensitive Mycobacterium tuberculosis.

scientific article published on 7 May 2013

Les cordes mycobactériennes

scientific article published on 01 May 2014

Lipomannan and lipoarabinomannan from a clinical isolate of Mycobacterium kansasii: novel structural features and apoptosis-inducing properties

scientific article (publication date: 19 September 2003)

Lipomannans, but not lipoarabinomannans, purified from Mycobacterium chelonae and Mycobacterium kansasii induce TNF-alpha and IL-8 secretion by a CD14-toll-like receptor 2-dependent mechanism

scientific article (publication date: 15 August 2003)

Looking through zebrafish to study host-pathogen interactions

scientific article

LosA, a key glycosyltransferase involved in the biosynthesis of a novel family of glycosylated acyltrehalose lipooligosaccharides from Mycobacterium marinum

scientific article published on 28 October 2005

Lsr2 Is an Important Determinant of Intracellular Growth and Virulence in

scientific article published on 30 April 2019

MAB_3551c encodes the primary triacylglycerol synthase involved in lipid accumulation in Mycobacterium abscessus.

scientific article published on 11 August 2016

Mechanistic and Structural Insights Into the Unique TetR-Dependent Regulation of a Drug Efflux Pump in Mycobacterium abscessus

scientific article published on 5 April 2018

MgtC as a Host-Induced Factor and Vaccine Candidate against Mycobacterium abscessus Infection.

scientific article published on August 2016

MmPPOX inhibits Mycobacterium tuberculosis lipolytic enzymes belonging to the hormone-sensitive lipase family and alters mycobacterial growth

scientific article

MmpL8 controls virulence and production of a previously unknown glycolipid family

article published in the Proceedings of the National Academy of Sciences of the United States of America

Molecular structure of EmbR, a response element of Ser/Thr kinase signaling in Mycobacterium tuberculosis.

scholarly article

Montpellier Infectious Diseases (MID), 2nd annual meeting (2012).

scientific article published on 14 February 2013

Mutations in the MAB_2299c TetR regulator confer cross-resistance to clofazimine and bedaquiline in

article

Mutations in the MAB_2299c TetR regulator confer cross-resistance to clofazimine and bedaquiline in Mycobacterium abscessus

scholarly article by Matthias Richard et al published 15 October 2018 in Antimicrobial Agents and Chemotherapy

Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune response

scientific article

Mycobacterial lipolytic enzymes: A gold mine for tuberculosis research ⬇️

scientific article published on July 20, 2012

Mycobacterial lipomannan induces MAP kinase phosphatase-1 expression in macrophages

scientific article

Mycobacterial lipomannan induces granuloma macrophage fusion via a TLR2-dependent, ADAM9- and beta1 integrin-mediated pathway

Mycobacterial lipomannan induces matrix metalloproteinase-9 expression in human macrophagic cells through a Toll-like receptor 1 (TLR1)/TLR2- and CD14-dependent mechanism.

scientific article

Mycobacterium abscessus alkyl hydroperoxide reductase C promotes cell invasion by binding to tetraspanin CD81

scientific article published in 2023

Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation.

scientific article published on 24 February 2014

Mycobacterium abscessus-Induced Granuloma Formation Is Strictly Dependent on TNF Signaling and Neutrophil Trafficking.

scientific article

Mycobacterium bovis BCG producing interleukin-18 increases antigen-specific gamma interferon production in mice.

scientific article

Mycobacterium lutetiense sp. nov., Mycobacterium montmartrense sp. nov. and Mycobacterium arcueilense sp. nov., members of a novel group of non-pigmented rapidly growing mycobacteria recovered from a water distribution system

scientific article

Mycobacterium marinum MgtC plays a role in phagocytosis but is dispensable for intracellular multiplication.

scientific article

Mycobacterium marinum lipooligosaccharides are unique caryophyllose-containing cell wall glycolipids that inhibit tumor necrosis factor-alpha secretion in macrophages

scientific article published on 02 June 2009

Mycobacterium tuberculosis S-adenosyl-l-homocysteine hydrolase is negatively regulated by Ser/Thr phosphorylation.

scientific article

Mycobacterium tuberculosis lipolytic enzymes as potential biomarkers for the diagnosis of active tuberculosis

scientific article (publication date: 2011)

Mycobacterium tuberculosis maltosyltransferase GlgE, a genetically validated antituberculosis target, is negatively regulated by Ser/Thr phosphorylation

scientific article published on 22 April 2013

Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis

scientific journal article

Mycolic acid methyltransferase, MmaA4, is necessary for thiacetazone susceptibility in Mycobacterium tuberculosis

scientific article published on 15 January 2009

Natural and Synthetic Flavonoids as Potent Mycobacterium tuberculosis UGM Inhibitors.

scientific article published on 11 May 2017

Negative regulation by Ser/Thr phosphorylation of HadAB and HadBC dehydratases from Mycobacterium tuberculosis type II fatty acid synthase system

scientific article published on 27 July 2011

Neutrophil killing of Mycobacterium abscessus by intra- and extracellular mechanisms.

scientific article published on 19 April 2018

New therapeutic strategies for pulmonary diseases - untapping the mycolic acid pathway

scientific article published in 2023

Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria.

scientific article

Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus

scientific article published on 21 February 2020

Oleic acid biosynthesis in Plasmodium falciparum: characterization of the stearoyl-CoA desaturase and investigation as a potential therapeutic target

scientific article published on 3 September 2009

Optimized Lysis-Extraction Method Combined With -Amplification for Detection of in Paucibacillary Sputum Specimens

scientific article published on 25 September 2018

Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis

scientific article published in October 2002

Overexpression of the KdpF membrane peptide in Mycobacterium bovis BCG results in reduced intramacrophage growth and altered cording morphology

scientific article

Overexpression of the Salmonella KdpF membrane peptide modulates expression of kdp genes and intramacrophage growth

scientific article published on 8 September 2014

Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis

scientific article

Phosphorylation of KasB regulates virulence and acid-fastness in Mycobacterium tuberculosis

scientific article (publication date: May 2014)

Phosphorylation of mycobacterial PcaA inhibits mycolic acid cyclopropanation: consequences for intracellular survival and for phagosome maturation block

scientific article

Phosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesis

scientific journal article

Point mutations within the fatty acid synthase type II dehydratase components HadA or HadC contribute to isoxyl resistance in Mycobacterium tuberculosis

scientific article published on 31 October 2012

Polysaccharide structural variability in mycobacteria: identification and characterization of phosphorylated mannan and arabinomannan

scientific article

Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis

scientific journal article

Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity

scientific article

Protein PknE, a novel transmembrane eukaryotic-like serine/threonine kinase from Mycobacterium tuberculosis

scientific journal article

Re-emergence of tuberculosis: strategies and treatment

scholarly article by Gurdyal Besra & Laurent Kremer published February 2002 in Expert Opinion on Investigational Drugs

Resistance to Thiacetazone Derivatives Active against Mycobacterium abscessus Involves Mutations in the MmpL5 Transcriptional Repressor MAB_4384.

scientific article

Rifabutin is bactericidal against intracellular and extracellular forms of Mycobacterium abscessus

scientific article published on 17 August 2020

Self-control of vitamin K2 production captured in the crystal

scientific article published on 01 March 2020

Severe inhibition of lipooligosaccharide synthesis induces TLR2-dependent elimination of Mycobacterium marinum from THP1-derived macrophages

scientific article

Structural analysis of an unusual bioactive N-acylated lipo-oligosaccharide LOS-IV in Mycobacterium marinum

scientific article published on 21 October 2010

Structural analysis of the N-acetyltransferase Eis1 from Mycobacterium abscessus reveals the molecular determinants of its incapacity to modify aminoglycosides

scientific article published on 28 August 2020

Structural determination and Toll-like receptor 2-dependent proinflammatory activity of dimycolyl-diarabino-glycerol from Mycobacterium marinum

scientific article

Structural rearrangements occurring upon cofactor binding in the Mycobacterium smegmatis β-ketoacyl-acyl carrier protein reductase MabA.

scientific article

Structural study of lipomannan and lipoarabinomannan from Mycobacterium chelonae. Presence of unusual components with alpha 1,3-mannopyranose side chains

scientific article (publication date: 23 August 2002)

Structure ofMycobacterium tuberculosismtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT)

scientific article

Structure-Based Design and Synthesis of Piperidinol-Containing Molecules as New Mycobacterium abscessus Inhibitors

scientific article published on 20 March 2020

Synergistic interactions of indole-2-carboxamides and β-lactam antibiotics against Mycobacterium abscessus

scientific article published on 10 February 2020

Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives

scientific article published on 22 December 2010

Synthesis and in vitro anti-tubercular evaluation of 1,2,3-triazole tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone chimeric scaffolds

scientific article published on 3 April 2012

Synthesis and in vitro antitubercular activity of ferrocene-based hydrazones.

scientific article

Synthesis, antitubercular activity and mechanism of resistance of highly effective thiacetazone analogues

scientific article

Synthesis, characterization and in vitro anti-Trypanosoma cruzi and anti-Mycobacterium tuberculosis evaluations of cyrhetrenyl and ferrocenyl thiosemicarbazones

scholarly article by Rodrigo Arancibia et al published April 2014 in Journal of Organometallic Chemistry

TLR2-dependent eosinophil interactions with mycobacteria: role of alpha-defensins

scientific article published on 31 October 2008

Targeting Mycolic Acid Transport by Indole-2-carboxamides for the Treatment of Mycobacterium abscessus Infections.

scientific article

Temperature-dependent regulation of mycolic acid cyclopropanation in saprophytic mycobacteria: role of the Mycobacterium smegmatis 1351 gene (MSMEG_1351) in CIS-cyclopropanation of alpha-mycolates

scientific article published on 10 May 2010

Temperature-induced changes in the cell-wall components of Mycobacterium thermoresistibile

scientific article published in October 2002

The C-Terminal Domain of the Virulence Factor MgtC Is a Divergent ACT Domain

scientific article

The Diverse Cellular and Animal Models to Decipher the Physiopathological Traits of Mycobacterium abscessus Infection.

scientific article published on 04 April 2017

The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

scientific article published on 11 December 2008

The Molecular Genetics of Mycolic Acid Biosynthesis

scientific article published on August 2014

The Mycobacterium tuberculosis FAS-II condensing enzymes: their role in mycolic acid biosynthesis, acid-fastness, pathogenesis and in future drug development

scientific article

The Mycobacterium tuberculosis GroEL1 chaperone is a substrate of Ser/Thr protein kinases

scientific article published on 06 February 2009

The Mycobacterium tuberculosis Ser/Thr Kinase Substrate Rv2175c Is a DNA-binding Protein Regulated by Phosphorylation

scientific article published on 17 July 2009

The Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III activity is inhibited by phosphorylation on a single threonine residue

scientific article

The Mycobacterium tuberculosis serine/threonine kinase PknL phosphorylates Rv2175c: mass spectrometric profiling of the activation loop phosphorylation sites and their role in the recruitment of Rv2175c

scientific journal article

The Mycobacterium tuberculosis transcriptional repressor EthR is negatively regulated by Serine/Threonine phosphorylation

scientific article published on 22 March 2014

The N-terminal domain of OmpATb is required for membrane translocation and pore-forming activity in mycobacteria

scientific article

The TetR Family Transcription Factor MAB_2299c Regulates the Expression of Two Distinct MmpS-MmpL Efflux Pumps Involved in Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus

scientific article published on 23 September 2019

The condensing activities of the Mycobacterium tuberculosis type II fatty acid synthase are differentially regulated by phosphorylation

scientific journal article

The crystal structure of the mycobacterial trehalose monomycolate transport factor A, TtfA, reveals an atypical fold

scientific article published on 12 December 2019

The distinct fate of smooth and rough Mycobacterium abscessus variants inside macrophages.

scientific article

The diverse family of MmpL transporters in mycobacteria: from regulation to antimicrobial developments.

scientific article published on 24 March 2017

The endogenous galactofuranosidase GlfH1 hydrolyzes mycobacterial arabinogalactan

scientific article published on 27 February 2020

The influence of AccD5 on AccD6 carboxyltransferase essentiality in pathogenic and non-pathogenic Mycobacterium

scientific article published on 16 February 2017

The methyl-branched fortifications of Mycobacterium tuberculosis

scientific article

The roles of tetraspanins in bacterial infections

scientific article published on 09 September 2020

The structure of Mycobacterium tuberculosis MPT51 (FbpC1) defines a new family of non-catalytic alpha/beta hydrolases

scientific article

The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds.

scientific article

Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria

scientific article

Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans

scientific article published in April 2004

Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid.

scientific article published on 13 August 2006

Use of the Salmonella MgtR peptide as an antagonist of the Mycobacterium MgtC virulence factor.

scientific article published on 5 February 2016

Variedly connected 1,8-naphthalimide-7-chloroquinoline conjugates: Synthesis, anti-mycobacterial and cytotoxic evaluation

scientific article published on 04 September 2019

Verapamil Improves the Activity of Bedaquiline against Mycobacterium abscessus In Vitro and in Macrophages

scientific article published on 23 August 2019

X-Ray Crystal Structure of Mycobacterium tuberculosis β-Ketoacyl Acyl Carrier Protein Synthase II (mtKasB)

scientific article

[New hopes for the treatment of persistent Mycobacterium abscessus infections?]

scientific article published on 21 August 2020

[The most ancestral mycobacterial ESX-4 secretion system is essential for intracellular growth of Mycobacterium abscessus within environmental and human phagocytes]

scientific article published on 01 October 2018

pETPhos: a customized expression vector designed for further characterization of Ser/Thr/Tyr protein kinases and their substrates

scientific article published in July 2008

pH-dependent pore-forming activity of OmpATb from Mycobacterium tuberculosis and characterization of the channel by peptidic dissection

scientific journal article

β-Lactamase inhibition by avibactam in Mycobacterium abscessus

scientific article published on 18 December 2014

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