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List of works by Thomas F Patterson

1210A Phase 3, Randomized, Double-Blind, Non-inferiority Trial to Evaluate Efficacy and Safety of Isavuconazole versus Voriconazole in Patients with Invasive Mold Disease (SECURE): Outcomes in Neutropenic Patients.

scientific article

1954. In vivo Efficacy of Delayed Therapy with the Novel Inositol Acyltransferase Inhibitor Fosmanogepix (APX001) in a Murine Model of Candida auris Invasive Candidiasis ⬇️

scientific article published on 23 October 2019

A murine model of Cryptococcus gattii meningoencephalitis

scientific article

A noninvasive renal fungus ball caused by Rhizopus--a previously unreported manifestation of zygomycosis

scientific article published in September 2010

A randomized study of the use of fluconazole in continuous versus episodic therapy in patients with advanced HIV infection and a history of oropharyngeal candidiasis: AIDS Clinical Trials Group Study 323/Mycoses Study Group Study 40.

scientific article published on 12 October 2005

A reference laboratory experience of clinically achievable voriconazole, posaconazole, and itraconazole concentrations within the bloodstream and cerebral spinal fluid

scientific article published on 4 November 2013

APX001A Protects Immunosuppressed Mice from Rhizopus delemar Infection

scientific article

Antifungal combinations against Candida albicans biofilms in vitro ⬇️

scientific article published on November 2003

Antifungal resistance in pathogenic fungi

scientific article (publication date: November 2002)

Antifungal susceptibilities among different serotypes of Cryptococcus gattii and Cryptococcus neoformans

scientific article published on 27 October 2008

Antifungal susceptibility testing of micafungin against Candida glabrata isolates

scientific article published in April 2008

Antifungal therapy and length of hospitalization in transplant patients with invasive aspergillosis

scientific article published on 11 June 2012

Antifungal treatment affects the laboratory diagnosis of invasive aspergillosis

scientific article published on 02 November 2011

Application of the 2008 definitions for invasive fungal diseases to the trial comparing voriconazole versus amphotericin B for therapy of invasive aspergillosis: a collaborative study of the Mycoses Study Group (MSG 05) and the European Organization

scientific article published on 19 November 2014

Aspergillosis. Pathogenesis, clinical manifestations, and therapy

scientific article

Aspergillus Polymerase Chain Reaction: Systematic Review of Evidence for Clinical Use in Comparison With Antigen Testing

scientific article

Aspergillus fumigatus stimulates leukocyte adhesion molecules and cytokine production by endothelial cells in vitro and during invasive pulmonary disease

scientific article published on 19 May 2008

Assessment of Aspergillus fumigatus burden in pulmonary tissue of guinea pigs by quantitative PCR, galactomannan enzyme immunoassay, and quantitative culture

scientific article published on 12 May 2008

Assessment of Aspergillus fumigatus in guinea pig bronchoalveolar lavages and pulmonary tissue by culture and realtime polymerase chain reaction studies

scientific article

Assessment of serum (1->3)-beta-D-glucan concentration as a measure of disease burden in a murine model of invasive pulmonary aspergillosis.

scientific article

Blastomyces helicus, a New Dimorphic Fungus Causing Fatal Pulmonary and Systemic Disease in Humans and Animals in Western Canada and the United States

article

Blastomyces helicus, an Emerging Dimorphic Fungal Pathogen Causing Fatal Pulmonary and Disseminated Disease in Humans and Animals in Western Canada and United States.

scientific article published on 4 October 2017

Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus

scientific article

Candida glabrata is an emerging cause of oropharyngeal candidiasis in patients receiving radiation for head and neck cancer

scientific article

Candida glabrata oropharyngeal candidiasis in patients receiving radiation treatment for head and neck cancer

scientific article published on May 2002

Candida krusei sepsis secondary to oral colonization in a hemopoietic stem cell transplant recipient

scientific article published on 01 March 2007

Caspofungin dose escalation for invasive candidiasis due to resistant Candida albicans. ⬇️

scientific article published on 18 April 2011

Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt.

scientific article published on 13 September 2006

Combination therapy with terbinafine and amphotericin B in a rabbit model of experimental invasive aspergillosis

scientific article

Comparison of Nonculture Blood-Based Tests for Diagnosing Invasive Aspergillosis in an Animal Model

scientific article published on 20 January 2016

Comparison of lateral flow technology and galactomannan and (1->3)-beta-D-glucan assays for detection of invasive pulmonary aspergillosis

scientific article published on 30 September 2009

Cost advantage of voriconazole over amphotericin B deoxycholate for primary treatment of invasive aspergillosis

scientific article published in June 2005

Current Concepts and Future Directions in the Pharmacology and Treatment of Coccidioidomycosis

scientific article published on 01 February 2019

Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance

scientific article published on 14 December 2020

Defining responses to therapy and study outcomes in clinical trials of invasive fungal diseases: Mycoses Study Group and European Organization for Research and Treatment of Cancer consensus criteria

scientific article published on September 2008

Detection and measurement of fungal burden in a guinea pig model of invasive pulmonary aspergillosis by novel quantitative nested real-time PCR compared with galactomannan and (1,3)-β-D-glucan detection

scientific article published on 21 December 2011

Detection of urinary excreted fungal galactomannan-like antigens for diagnosis of invasive aspergillosis

scientific article

Development and evaluation of a calibrator material for nucleic acid-based assays for diagnosing aspergillosis

scientific article published on 24 April 2013

Development of caspofungin resistance following prolonged therapy for invasive candidiasis secondary to Candida glabrata infection. ⬇️

scientific article published on August 2008

Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production

scientific article

Early treatment of candidemia in adults: a review

scientific article published on 06 September 2010

Effect of Antifungal Treatment in a Diet-Based Murine Model of Disseminated Candidiasis Acquired via the Gastrointestinal Tract.

scientific article published on 29 August 2016

Efficacy and safety of caspofungin for treatment of invasive aspergillosis in patients refractory to or intolerant of conventional antifungal therapy

scientific article published on 9 November 2004

Efficacy of Delayed Therapy with Fosmanogepix (APX001) in a Murine Model of Candida auris Invasive Candidiasis ⬇️

scientific article published on 22 October 2019

Efficacy of caspofungin alone and in combination with voriconazole in a Guinea pig model of invasive aspergillosis

scientific article published on August 2002

Efficacy of liposomal amphotericin B and posaconazole in intratracheal models of murine mucormycosis

scientific article published on 06 May 2013

Efficacy of posaconazole as treatment and prophylaxis against Fusarium solani

scientific article published on 11 January 2010

Efficacy of ravuconazole (BMS-207147) in a guinea pig model of disseminated aspergillosis

scientific article published in February 2002

Efficacy of the investigational echinocandin ASP9726 in a guinea pig model of invasive pulmonary aspergillosis

scientific article published on 9 March 2015

Emergence of Azole Resistance in Aspergillus

scientific article published on 23 September 2015

Emergomyces canadensis, a Dimorphic Fungus Causing Fatal Systemic Human Disease in North America.

scientific article published in April 2018

Erratum for Mor et al., "Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids".

scientific article published on 13 March 2018

Evaluation of Etest method for determining isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans.

scientific article published on 16 June 2008

Evaluation of Sex Differences in Murine Diabetic Ketoacidosis and Neutropenic Models of Invasive Mucormycosis

scientific article published in 2021

Evaluation of an early step-down strategy from intravenous anidulafungin to oral azole therapy for the treatment of candidemia and other forms of invasive candidiasis: results from an open-label trial

scientific article

Executive Summary: Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America.

scientific article published on August 2016

Extended-Interval Dosing of Rezafungin against Azole-Resistant Aspergillus fumigatus

scientific article published on 23 September 2019

Factors associated with mortality in transplant patients with invasive aspergillosis

scientific article

Fosmanogepix (APX001) is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus

scientific article published on 23 March 2020

Fungal Infections Associated with Contaminated Methylprednisolone Injections ⬇️

scientific article published on October 19, 2012

Fungal Infections Potentiated by Biologics

scientific article published on 22 April 2020

Fungal Outbreak Update From IDWeek ⬇️

scientific article published on October 24, 2012

Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids

scientific article published on 23 June 2015

Imaging findings in acute invasive pulmonary aspergillosis: clinical significance of the halo sign

scientific article

Immune reconstitution inflammatory syndrome after cessation of the tumor necrosis factor alpha blocker adalimumab in cryptococcal pneumonia

scientific article published in July 2009

Impact of unresolved neutropenia in patients with neutropenia and invasive aspergillosis: a post hoc analysis of the SECURE trial

scientific article published on 29 November 2017

In Vivo Efficacy of VT-1129 against Experimental Cryptococcal Meningitis with the Use of a Loading Dose-Maintenance Dose Administration Strategy

article

In vitro Activity of Fosfomycin, Alone and Combined with Cefepime and Meropenem, Against Carbapenemase-Producing Gram-Negative Bacteria.

scientific article published on 4 October 2017

In vitro activity of caspofungin (MK-0991) against Candida albicans clinical isolates displaying different mechanisms of azole resistance

scientific article published on June 2002

In vitro activity of caspofungin against Candida albicans biofilms.

scientific article

In vitro activity of isavuconazole against Trichosporon, Rhodotorula, Geotrichum, Saccharomyces and Pichia species

scientific article published on 30 April 2009

In vitro interaction of caspofungin acetate with voriconazole against clinical isolates of Aspergillus spp.

scientific article published on September 2002

In vivo analysis of Aspergillus fumigatus developmental gene expression determined by real-time reverse transcription-PCR

scientific article published on 19 May 2008

Inhaled voriconazole for prevention of invasive pulmonary aspergillosis.

scientific article published on 16 March 2009

Interlaboratory and interstudy reproducibility of a novel lateral-flow device and influence of antifungal therapy on detection of invasive pulmonary aspergillosis.

scientific article published on 21 November 2012

Invasive Aspergillosis as an Under-recognized Superinfection in COVID-19

scientific article published on 19 June 2020

Invasive Aspergillosis: Current Strategies for Diagnosis and Management

scientific article published on March 2016

Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET).

scientific article published in April 2010

Invasive non-Aspergillus mold infections in transplant recipients, United States, 2001-2006.

scientific article published in October 2011

Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms

scientific article published in June 2002

Isavuconazole Is Effective for the Treatment of Experimental Cryptococcal Meningitis

scientific article published on 20 June 2016

Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3, randomised-controlled, non-inferiority trial

scientific article published on 9 December 2015

Limited activity of miltefosine in murine models of cryptococcal meningoencephalitis and disseminated cryptococcosis

scientific article published on 19 November 2012

Loss of in vitro resistance in Candida glabrata following discontinuation of fluconazole prophylaxis in a hematopoietic stem cell transplantation patient.

scientific article

Micafungin (FK463), alone or in combination with other systemic antifungal agents, for the treatment of acute invasive aspergillosis

scientific article published on 6 May 2006

Microbiology and epidemiology of oral yeast colonization in hemopoietic progenitor cell transplant recipients.

scientific article published on 9 January 2013

Modified release itraconazole amorphous solid dispersion to treat Aspergillus fumigatus: importance of the animal model selection.

scientific article

Molecular mechanisms of fluconazole resistance in Candida dubliniensis isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis

scientific article

Multicenter, noncomparative study of caspofungin in combination with other antifungals as salvage therapy in adults with invasive aspergillosis

scientific article published on 01 December 2006

Multiple Brain Abscesses Caused by Trichosporon inkin in a Patient with X-Linked Chronic Granulomatous Disease (CGD) Successfully Treated with Antifungal Therapy.

scientific article published on 11 July 2017

Multiple patterns of resistance to fluconazole in Candida glabrata isolates from a patient with oropharyngeal candidiasis receiving head and neck radiation

scientific article

New Concepts in Diagnostics for Invasive Mycoses: Non-Culture-Based Methodologies

article

New guinea pig model of Cryptococcal meningitis

scientific article published on 11 June 2007

New immunosuppressive agents and risk for invasive fungal infections

scientific article published on 01 November 2009

Nosocomial Outbreak ofExophiala jeanselmeiFungemia Associated with Contamination of Hospital Water

scientific article published in 2002

Open-Label Crossover Oral Bioequivalence PK Comparison for a 3-Day Loading Dose Regimen and 15-Day Steady-State Administration of SUBA™-Itraconazole and Conventional Itraconazole Capsules in Healthy Adults

scientific article published on 26 May 2020

Oral glucan synthase inhibitor SCY-078 is effective in an experimental murine model of invasive candidiasis caused by WT and echinocandin-resistant Candida glabrata ⬇️

scientific article published on 21 November 2017

Oropharyngeal candidiasis caused by non-albicans yeast in patients receiving external beam radiotherapy for head-and-neck cancer

scientific article published in September 2003

Oropharyngeal candidiasis in the era of antiretroviral therapy

scientific article

Phaeohyphomycosis in transplant recipients: Results from the Transplant Associated Infection Surveillance Network (TRANSNET).

scientific article published on 23 April 2015

Polymerase Chain Reaction Detection ofAspergillusDNA in Experimental Models of Invasive Aspergillosis

scientific article published on 01 April 2002

Posaconazole therapeutic drug monitoring: a reference laboratory experience

scientific article published on 2 March 2009

Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America

scientific article

Prolyl endopeptidase activity in bronchoalveolar lavage fluid: a novel diagnostic biomarker in a guinea pig model of invasive pulmonary aspergillosis

scientific article

Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.

scientific article published on 26 June 2017

Prophylactic efficacy of single dose pulmonary administration of amphotericin B inhalation powder in a guinea pig model of invasive pulmonary aspergillosis

scientific article published on 11 January 2012

Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database.

scientific article

Proteinase detection, DNA typing and antimycotic susceptibility of Candida isolates from Colombian women with vulvovaginal candidiasis

scientific article

Pulmonary Aspergillosis: Recent Advances ⬇️

scientific article published on December 13, 2011

Pulmonary aspergillosis

scientific article published on 01 April 2008

Rapid emergence of echinocandin resistance in Candida glabrata resulting in clinical and microbiologic failure.

scientific article published on July 2013

Real-world experience in the midst of an Exserohilum meningitis outbreak

scientific article published in June 2013

Replacement of Candida albicans with C. dubliniensis in human immunodeficiency virus-infected patients with oropharyngeal candidiasis treated with fluconazole

scientific article

Repurposing auranofin as an antifungal: In vitro activity against a variety of medically important fungi.

scientific article published on 07 June 2016

Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion

scientific article published on 22 June 2020

Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/

scientific article published on June 2008

Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium

scientific article published on 05 December 2019

Screening a Repurposing Library for Inhibitors of Multidrug-Resistant Candida auris Identifies Ebselen as a Repositionable Candidate for Antifungal Drug Development

scientific article published on 24 September 2018

Screening for drug-resistant Candida yeasts with chromogenic agar

scientific article

Sequential or combination antifungal therapy with voriconazole and liposomal amphotericin B in a Guinea pig model of invasive aspergillosis

scientific article published on April 2006

Should the consensus guidelines' specific criteria for the diagnosis of invasive fungal infection be changed?

scientific article

Standardization of an experimental murine model of invasive pulmonary aspergillosis

scientific article

Strategy of following voriconazole versus amphotericin B therapy with other licensed antifungal therapy for primary treatment of invasive aspergillosis: impact of other therapies on outcome

scientific article published on 13 October 2005

The C-terminal antibody binding domain of Candida albicans mp58 represents a protective epitope during candidiasis

scientific article published in March 2004

The Carbohydrate Lectin Receptor Dectin-1 Mediates the Immune Response to Exserohilum rostratum.

scientific article

The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis

scientific article

The Changing Epidemiology of Oropharyngeal Candidiasis in Patients with HIV/AIDS in the Era of Antiretroviral Therapy

scientific article

The Emerging Threat of Antifungal Resistance in Transplant Infectious Diseases

scientific article published on 5 February 2018

The Fungal Cyp51 Inhibitor VT-1129 Is Efficacious in an Experimental Model of Cryptococcal Meningitis

scientific article published on 27 August 2018

The Fungal Cyp51-Specific Inhibitor VT-1598 Demonstrates and Activity against Candida auris

scholarly article by Nathan P Wiederhold et al published March 2019 in Antimicrobial Agents and Chemotherapy

The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii.

scientific article published on 19 January 2016

The Novel Arylamidine T-2307 Demonstrates In Vitro and In Vivo Activity against Candida auris

scientific article published on 21 February 2020

The Novel Fungal Cyp51 Inhibitor VT-1598 is Efficacious in Experimental Models of Central Nervous System Coccidioidomycosis Caused by Coccidioides posadasii and Coccidioides immitis.

scientific article published on 5 February 2018

The Orotomide Olorofim Is Efficacious in an Experimental Model of Central Nervous System Coccidioidomycosis

scientific article published on 27 August 2018

The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET).

scientific article

The investigational agent E1210 is effective in treatment of experimental invasive candidiasis caused by resistant Candida albicans ⬇️

scientific article

The novel arylamidine T-2307 demonstrates in vitro and in vivo activity against echinocandin-resistant Candida glabrata

scientific article published on 29 November 2015

The novel arylamidine T-2307 maintains in vitro and in vivo activity against echinocandin-resistant Candida albicans.

scientific article

Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America

scientific article

Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial

scientific article

Utility of CT assessment in hematology patients with invasive aspergillosis: a post-hoc analysis of phase 3 data

scientific article published on 28 May 2019

VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection

scientific article published on 14 September 2015

Voriconazole use and pharmacokinetics in combination with interferon-gamma for refractory cryptococcal meningitis in a patient receiving low-dose ritonavir

scientific article published in May 2010

Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis

scientific article (publication date: 8 August 2002)

What's new in antifungals: an update on the in-vitro activity and in-vivo efficacy of new and investigational antifungal agents.

scientific article published on 15 September 2015

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